Contributions of Indian Council of Medical Research (ICMR) in the area of Medicinal plants/Traditional medicine

Abstract: The study were conducted at Dilla University, College of Natural Sciences, Biological Sciences laboratories. Background: Ethiopia is a country with many ethnic groups, cultures and beliefs which in turn have contributed to the high diversity of traditional health care knowledge and practices of traditional medicine from local growth plants, animals and minerals for various physical and mental disorders of human and livestock population that passed from generation to generation for centuries. Medicinal plants contributors to pharmaceutical, agricultural and food industries in the world. The use of medicinal plants in the industrialized societies has been traced to extraction and development of several drugs used in order to heel some diseases having inhibiting effect against pathogenic microorganism. Objective: The main objective of this study was Extraction and Phytochemicals determination of traditional medicinal plants for anti microbial susceptibility test. Methodology: The extraction and identification of some phytochemicals crude compound which used for antimicrobial susceptibility test from plant sample such as Ocimum lamiifolium (OL), Croton maerosth (Cm) and Ruta chalepesis (RC) were conducted. Plant samples are collected, powdered using mortal and pistil and extracted using ethanol and some susceptibility tests were performed to identify some phytochemicals compound. Result: The main result of Antimicrobial activity test showed that the crude extract of OL has the highest zone of inhibition. The highest yield of crude extract (38.21%) was obtained from Croton maerosth (CM) which followed by Ruta chalepesis (RC) (32.43%). However, the lowest yield (28.37%) was obtained from Oscpmum lamifolium (OL). Conclusion: Traditional Medicine is used by many people to managing numerous conditions; it’s accessible and effective on antimicrobial activity. Therefore, it plays a significant role by reducing life-threatening ailments of people and other animals.

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Pemanfaatan Tumbuhan Obat Tradisional oleh Etnis Sangihe di Kepulauan Sangihe Bagian Selatan, Sulawesi Utara (The Usage of Traditional Medicinal Plants by Sangihe Ethnic in the Southern Sangihe Islands, North Sulawesi)

JURNAL BIOS LOGOS ◽

10.35799/jbl.8.2.2018.21446 ◽

2018 ◽

Vol 8 (2) ◽

pp. 45

Author(s):

Chrisye Yustitia Pelokang ◽

Roni Koneri ◽

Deidy Katili

Keyword(s):

Medicinal Plants ◽

Traditional Medicine ◽

Plant Species ◽

Structured Interviews ◽

Active Components ◽

Plant Materials ◽

Medical Practitioners ◽

North Sulawesi ◽

Traditional Medicinal Plants ◽

Plant Families

Abstrak Tumbuhan obat merupakan tumbuhan yang menghasilkan satu atau lebih komponen aktif yang dipercaya oleh penduduk berkhasiat obat sehingga dimanfaatkan dalam pengobatan tradisional. Penelitian ini bertujuan untuk mengidentifikasi dan mengkaji spesies tumbuhan yang digunakan sebagai obat tradisional oleh Etnis Sangihe di Kepulauan Sangihe bagian Selatan, Sulawesi Utara. Pengambilan data dilakukan melalui wawancara terstruktur yang diajukan kepada pengobat tradisional. Hasil penelitian menunjukkan adanya 38 spesies dari 25 famili tumbuhan yang dimanfaatkan sebagai tumbuhan obat oleh Etnis Sangihe bagian Selatan. Herba merupakan habitus tumbuhan yang banyak dimanfaatkan untuk bahan pengobatan. Bagian tumbuhan yang paling banyak digunakan sebagai obat yaitu daun. Cara pengolahan yang paling banyak digunakan adalah direbus. Jenis penyakit yang dapat diobati dengan tumbuhan obat sebanyak 22 jenis penyakit. Kata kunci: tumbuhan obat, obat tradisional, habitus, Kepulauan Sangihe Bagian Selatan Abstract Medicinal plants are plants that produce one or more active components that are believed by local people as medicinal plants for traditional medicine practices. This study aimed to identify and to assess the plant species that used as traditional medicine by the Sangihe Ethnic in the Southern Sangihe Islands, North Sulawesi. Data collection was conducted by structured interviews to the indigenous medical practitioners. The results showed that 38 plant species from 25 plant families were used as medicinal plants by the Southern Sangihe Ethnic people. Herbs were plant habitus that were widely used for medicinal ingredients. The leaves were widely used as medicinal plant materials. Boiling was the most processing method for preparing medicinal herbs. There were 22 types of diseases that could be treated using medicinal plants. Keywords: medicinal plants, traditional medicine, habitus, Southern Sangihe Islands

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The Current Outbreak of COVID-19 with reference to India

Coronaviruses ◽

10.2174/2666796701999201026203911 ◽

2020 ◽

Vol 01 ◽

Author(s):

Harshita Gupta

Keyword(s):

Medical Research ◽

Preventive Measures ◽

Antiviral Drug ◽

Treatment Strategies ◽

Highly Pathogenic ◽

Indian Council ◽

Current Outbreak ◽

Novel Coronavirus ◽

Bat Coronavirus ◽

Viral Outbreak

Abstract:: This review summarizes the outbreak of viruses causing the fatal disease which is highly pathogenic and human to human transmittable and it first emerges in Wuhan, China and now this epidemic situation becomes worldwide. A novel coronavirus (2019-nCoV) or severe acute respiratory syndrome coronavirus(SARS-CoV)-2 belongs to β-coronavirus genera which were originated in bats due to highly identical genome with bat coronavirus. This review highlights the Indian Council of Medical Research, India study which determined the detection of pathogenic coronavirus in two species of Indian bats. Indian Council of Medical Research, India has successfully isolated the COVID-19 virus strain which was the first step towards diagnosis and the development of vaccines in the country. The outbreaks of coronavirus received worldwide attention for overcoming the challenges faced during this current pandemic as there is no clinically approved antiviral drug or vaccine available, however, preventive measures and different treatments were taken to cope with this viral outbreak. In response to this global outbreak, this review tries to explain the Virology, Epidemiology, pathogenesis, and discusses the Diagnosis, treatment strategies of COVID-19. This review emphasizes the current update of knowledge about COVID-19.

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Validation of Indian Council of Medical Research Neurocognitive Tool Box in Diagnosis of Mild Cognitive Impairment in India: Lessons from a Harmonization Process in a Linguistically Diverse Society

Dementia and Geriatric Cognitive Disorders ◽

10.1159/000512393 ◽

2021 ◽

pp. 1-10

Author(s):

Ramshekhar N. Menon ◽

Feba Varghese ◽

Avanthi Paplikar ◽

Shailaja Mekala ◽

Suvarna Alladi ◽

...

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Medical Research ◽

Sensitivity And Specificity ◽

Linguistically Diverse ◽

Z Score ◽

Indian Languages ◽

Test Protocol ◽

Indian Council ◽

Multiple Domain

Background/Aims: In a linguistically diverse country such as India, challenges remain with regard to diagnosis of early cognitive decline among the elderly, with no prior attempts made to simultaneously validate a comprehensive battery of tests across domains in multiple languages. This study aimed to determine the utility of the Indian Council of Medical Research-Neurocognitive Tool Box (ICMR-NCTB) in the diagnosis of mild cognitive impairment (MCI) and its vascular subtype (VaMCI) in 5 Indian languages. Methods: Literate subjects from 5 centers across the country were recruited using a uniform process, and all subjects were classified based on clinical evaluations and a gold standard test protocol into normal cognition, MCI, and VaMCI. Following adaptation and harmonization of the ICMR-NCTB across 5 different Indian languages into a composite Z score, its test performance against standards, including sensitivity and specificity of the instrument as well as of its subcomponents in diagnosis of MCI, was evaluated in age and education unmatched and matched groups. Results: Variability in sensitivity-specificity estimates was noted between languages when a total of 991 controls and 205 patients with MCI (157 MCI and 48 VaMCI) were compared due to a significant impact of age, education, and language. Data from a total of 506 controls, 144 patients with MCI, and 46 patients with VaMCI who were age- and education-matched were compared. Post hoc analysis after correction for multiple comparisons revealed better performance in controls relative to all-cause MCI. An optimum composite Z-score of −0.541 achieved a sensitivity of 81.1% and a specificity of 88.8% for diagnosis of all-cause MCI, with a high specificity for diagnosis of VaMCI. Using combinations of multiple-domain 2 test subcomponents retained a sensitivity and specificity of >80% for diagnosis of MCI. Conclusions: The ICMR-NCTB is a “first of its kind” approach at harmonizing neuropsychological tests across 5 Indian languages for the diagnosis of MCI due to vascular and other etiologies. Utilizing multiple-domain subcomponents also retains the validity of this instrument, making it a valuable tool in MCI research in multilingual settings.

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Ethnobotanical survey of an -diabe c plants applied in West of Algeria

South Asian Journal of Experimental Biology ◽

10.38150/sajeb.8(2).p57-62 ◽

2019 ◽

Vol 8 (2) ◽

pp. 57-62

Author(s):

W Kouadri Boudjelthia ◽

K Hammadi ◽

M Kouidri ◽

A Noui ◽

N Djebli

Keyword(s):

Medicinal Plants ◽

Traditional Medicine ◽

Data Base ◽

Broad Spectrum ◽

Western Region ◽

Ethnobotanical Survey ◽

Valuable Data ◽

Berberis Vulgaris ◽

Aerial Parts ◽

Set Up

This study was carried out in order to set up an inventory list of medicinal plants used in traditional medicine to treat diabetes for which an ethnobotanical test was carried out on 670 diabe c subjects in the Western region of Algeria (Chlef, Mostaganem, Mascara, Oran, Sidi-bel-Abbes, Saida and Tiaret) using a survey. 24 an hyperglycemic medicinal plants were listed of which Berberis vulgaris, Zygophyllum geslini, Erythraea centaurium and Olea eu- ropea represented a broad spectrum of use. Likewise, the an hyperglycemic recipes were prepared mainly in decoc on (45.37%) and infusion (39.62%), and from leaves (42%) and aerial parts (16%). A very valuable data base has been reported for further research, especially for some elds such as phytochemistry and phytopharmacology that aim to identify new natural principles.

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