Blood types in Bengal cats in the UK

2009 ◽  
Vol 11 (10) ◽  
pp. 826-828 ◽  
Author(s):  
Danièlle A. Gunn-Moore ◽  
Kerry E. Simpson ◽  
Michael J. Day
Keyword(s):  
Blood Sample ◽  
Type A ◽  
Blood Type ◽  
Type B ◽  
Microtitre Plate ◽  
Blood Typing ◽  
Blood Samples ◽  
Microtitre Plate Assay ◽  
The Uk ◽  
Type Ab

Blood samples from 100 adult Bengal cats from the UK were submitted for assessment of blood type using RapidVet-H Feline blood typing cards (dms Laboratories), with further assessment by standard blood typing in a microtitre plate assay when card typing was inconclusive or revealed blood type B or AB. Ninety-eight cats were found to be type A when assessed using the blood typing cards. One cat initially tested as type AB but was found to be type A on testing a second blood sample using the blood typing cards. One cat initially tested as type B but was found to be type A when a second sample was tested by standard blood typing assay. Finding that 100% of the cats were blood type A is in contrast with previous studies that reported 10 Bengal cats to be type A, four to be type AB and one to be type B.

scholarly journals Signalment and Blood Types in Cats Being Evaluated as Blood Donors at Two Italian University Blood Banks

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Eva Spada ◽  
Arianna Miglio ◽  
Daniela Proverbio ◽  
Maria Teresa Antognoni ◽  
Giada Bagnagatti De Giorgi ◽  
...  
Keyword(s):  
Blood Donors ◽  
Type A ◽  
Blood Type ◽  
Transfusion Reaction ◽  
Type B ◽  
Blood Typing ◽  
Blood Types ◽  
Blood Banks ◽  
Type Ab ◽  
Transfusion Reactions

Data from potential feline blood donors presented at two university blood banks in Italy were recorded. Blood typing was performed using an immunochromatographic method. Over the three years of the study 357 cats representing 15 breeds, 45.3% female and 54.7% male, with a mean age of 3.8 years were evaluated. Of these 90.5% were blood type A, 5.6% type B, and 3.9% type AB. The majority of the cats (54.6%) were European DSH (92.3% were type A, 5.1% type B, and 2.6% type AB), and 21% were Maine Coon (MCO) cats (100% blood type A). The estimated frequencies of transfusion reactions following an unmatched transfusion between DSH (donors and recipients), MCO (donor and recipients), DSH donors and MCO recipients, and MCO donors and DSH recipients were 4.8%, 0%, 0%, and 5.1% for major reactions and 7.2%, 0%, 7.7%, and 0% for minor transfusions reactions, respectively. In a population of blood donors that includes DSH and MCO the risk of transfusion reaction is between 5% and 8% if typing is not performed on donor and recipient blood. Blood typing should therefore be performed before transfusion to remove the risk of transfusion reactions due to blood type incompatibilities.

scholarly journals Prevalence of Blood Types and Alloantibodies of the AB Blood Group System in Non-Pedigree Cats from Northern (Lombardy) and Southern (Sicily) Italy

Animals ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1129 ◽  
Author(s):  
Eva Spada ◽  
Roberta Perego ◽  
Luciana Baggiani ◽  
Elisabetta Salatino ◽  
Vito Priolo ◽  
...  
Keyword(s):  
Blood Group ◽  
Southern Italy ◽  
Type A ◽  
Regional Studies ◽  
Blood Group System ◽  
Type B ◽  
Blood Typing ◽  
Blood Types ◽  
Significant Difference ◽  
Type Ab

The aims of this study were to determine the prevalence of A, B and AB blood types and alloantibodies in non-pedigree cats from two regions, one in Northern and one in Southern Italy (Lombardy and Sicily, respectively). A total of 448 samples (52.0% from Northern and 48.0% from Southern Italy) were blood typed. The prevalence of A, B and AB blood types in northern and southern cats were 91.0%, 5.2%, 3.8%, and 77.2%, 12.1% and 10.7%, respectively. The prevalence of type-A blood in southern cats was significantly lower (p = 0.0001) than in northern cats, while type-B and AB blood were significantly higher (p = 0.0085 and p = 0.0051, respectively) in Southern compared to Northern Italian cats. Alloantibodies against type-A blood were found in 94.1% of type-B cats, 11.2% of type-A cats had alloantibodies against type-B blood, while no type-AB cats had alloantibodies with no significant difference between the two Italian populations. Type-AB prevalence in non-pedigree cats in Southern Italy was the highest reported in Europe. Italian type-A cats had the lowest worldwide prevalence of alloantibodies against type-B blood. These results highlight the usefulness of regional studies to report different prevalences in feline blood types and reinforce the importance of blood typing cats before transfusions and mating.

scholarly journals Assessment of risks of feline mismatched transfusion and neonatal isoerythrolysis in the Lyon (France) area

2019 ◽  
Vol 5 (2) ◽  
pp. 205511691986317 ◽  
Author(s):  
Alexandra Nectoux ◽  
Maryline Guidetti ◽  
Anthony Barthélemy ◽  
Céline Pouzot-Nevoret ◽  
Guillaume L Hoareau ◽  
...  
Keyword(s):  
Relative Frequency ◽  
Blood Type ◽  
Transfusion Reaction ◽  
Type B ◽  
Immunochromatographic Strip ◽  
Blood Typing ◽  
Blood Samples ◽  
Blood Types ◽  
Study Population ◽  
A Minor

Objectives The aims of this study were to update the prevalence of different feline blood types in the Lyon (France) area, as well as to determine the risk of mismatched transfusion (MT) and neonatal isoerythrolysis (NI) in kittens with parents of unknown blood type. Methods Blood samples were obtained from blood donor cats and cats admitted to an intensive care unit in Lyon. AB blood typing was performed using an immunochromatographic strip. The risk of MT was estimated by adding the risk of a major transfusion reaction and the risk of a minor transfusion reaction. The risk of NI was estimated according the equation (p²)(q²) + 2pq(q²), with q being the b allele frequency and p = 1 – q. The results were analysed by absolute and relative frequency analysis and multivariate analysis. Results The cohort study population included 320 non-pedigree cats and 37 pedigree cats. The prevalence of blood types A, B and AB was 84.3%, 14.0% and 1.7%, respectively. Considering non-pedigree cats, the prevalence of types A, B and AB was 83.7%, 14.4% and 1.9%, respectively. There were no significant differences of blood type distribution by sex ( P = 0.73) or by breed ( P = 0.90). Based on these percentages, the risks of MT and NI in non-pedigree cats were 24.3% and 12.3%, respectively. Conclusions and relevance The prevalence of type B cats is high in the Lyon area and associated with high risks of MT and NI. These results confirm the importance of performing blood typing prior to any blood transfusion or mating.

scholarly journals N-glycolylneuraminic acid and N-acetylneuraminic acid define feline blood group A and B antigens

Blood ◽  
1992 ◽  
Vol 79 (9) ◽  
pp. 2485-2491 ◽  
Author(s):  
GA Andrews ◽  
PS Chavey ◽  
JE Smith ◽  
L Rich
Keyword(s):  
Membrane Protein ◽  
Blood Group ◽  
Type A ◽  
Blood Type ◽  
Blood Group Antigens ◽  
Type B ◽  
Western Blots ◽  
Acetylneuraminic Acid ◽  
Group A ◽  
Type Ab

Abstract Blood group incompatibility causes transfusion reactions and neonatal isoerythrolysis in cats. We investigated the molecular nature of the blood group antigens from cats that had blood type A, B, and AB erythrocytes. Naturally occurring anti-type B antibodies, Triticum vulgaris lectin, monoclonal antibody (MoAb) 32–27, and MoAb R-24 were used in agglutination tests, Western blots, and thin-layer chromatography (TLC) enzyme immunostaining. Type A erythrocytes had NeuGc-NeuGc-Galactose-Glucose-Ceramide ([NeuGc]2GD3) where NeuGc represents N-glycolylneuraminic acid, and NeuAc-NeuGc-GD3, where NeuAc represents N-acetylneuraminic acid, and may have [NeuGc]2 disialylparagloboside and NeuAc-NeuGc-disialylparagloboside. Type B erythrocytes only had [NeuAc]2GD3. Type AB erythrocytes had [NeuGc]2GD3, NeuAc-NeuGc-GD3, and [NeuAc]2GD3. Blood group antigens were also found on a 50-Kd membrane protein. We conclude that type B erythrocytes are characterized by [NeuAc]2GD3 as the only form of this ganglioside and the presence of NeuAc on a 50-Kd membrane protein. NeuGc is the major determinant of the A antigen; specifically, [NeuGc]2GD3 is the major glycolipid form. The A antigen is also present on a 50-Kd membrane protein.

scholarly journals Frequencies of feline blood types in Hungary

2001 ◽  
Vol 49 (4) ◽  
pp. 369-375 ◽  
Author(s):  
Nóra Bagdi ◽  
Melinda Magdus ◽  
E. Leidinger ◽  
Judith Leidinger ◽  
K. Vörös
Keyword(s):  
Blood Transfusion ◽  
Blood Group ◽  
Diagnostic Method ◽  
Type A ◽  
Blood Groups ◽  
Blood Type ◽  
Type B ◽  
Blood Types ◽  
Type Ab ◽  
Transfusion Reactions

Feline blood group determination is done as a routine diagnostic method in numerous countries. Blood transfusion reactions and feline neonatal isoerythrolysis (FNI) can be avoided with the identification of different feline blood groups. The present study is the first investigation in Hungary during which 100 cats have been examined from all over the country. These cats were out of six breeds: European domestic shorthair, Persian mix, Persian, Abyssinian, Siamese and British shorthair. In the Hungarian feline population European domestic shorthair are most common but other breeds also occur. European domestic shorthair, Persian mix, Abyssinian, Siamese and British shorthair individuals all belonged to blood type A (100%). Blood type B was found very rarely and only in Persian cats. One-third of the Persian cats were categorised into blood type B, whilst type AB was not found during the study.

Titres of alloantibodies against A and B blood types in non-pedigree domestic cats in Turkey: Assessing the transfusion reaction risk

2005 ◽  
Vol 7 (5) ◽  
pp. 301-305 ◽  
Author(s):  
Mehmet Gurkan ◽  
Şevket Arikan ◽  
Ebru Ozaytekin ◽  
Tamer Dodurka
Keyword(s):  
Type A ◽  
Blood Type ◽  
Severe Reaction ◽  
Red Cell ◽  
Transfusion Reaction ◽  
Type B ◽  
Domestic Cats ◽  
Cell Destruction ◽  
Type Ab ◽  
Transfusion Reactions

The severity of a transfusion reaction depends on alloantibody titres within the recipients' blood. Determination of an agglutination titre of naturally occurring alloantibody may help to assess the risk of transfusion reactions following an unmatched transfusion in a cat population. In this group of 312 cats 227 had blood type A, 78 had blood type B, and seven had type AB blood. All type B cats tested showed gross evidence of agglutinating anti-A antibody with plasma titres ranging from 2 to 256. Among the 227 type A domestic cats tested for plasma anti-B alloantibody titres, 70% had gross agglutination with titres ranging from 2 to 16, while 17.6% had microscopic agglutination. The remaining 12.4% of the type A cats were negative for both gross and microscopic agglutination. Based on agglutinating titres, the relative risk of a transfusion reaction when type A or AB blood was given to a type B cat was 6.4% with acute severe reaction, acute mild reactions in 85.9% and premature red cell destruction in 7.7%. On the other hand, transfusion of type AB blood or type B blood to type A cats carries a potential risk of acute mild transfusion reaction in 4.4% and premature red cell destruction in 83.3%. Transfusion of type A or B blood to type AB cats results in no apparent clinical transfusion reactions.

scholarly journals N-glycolylneuraminic acid and N-acetylneuraminic acid define feline blood group A and B antigens

Blood ◽  
1992 ◽  
Vol 79 (9) ◽  
pp. 2485-2491 ◽  
Author(s):  
GA Andrews ◽  
PS Chavey ◽  
JE Smith ◽  
L Rich
Keyword(s):  
Membrane Protein ◽  
Blood Group ◽  
Type A ◽  
Blood Type ◽  
Blood Group Antigens ◽  
Type B ◽  
Western Blots ◽  
Acetylneuraminic Acid ◽  
Group A ◽  
Type Ab

Blood group incompatibility causes transfusion reactions and neonatal isoerythrolysis in cats. We investigated the molecular nature of the blood group antigens from cats that had blood type A, B, and AB erythrocytes. Naturally occurring anti-type B antibodies, Triticum vulgaris lectin, monoclonal antibody (MoAb) 32–27, and MoAb R-24 were used in agglutination tests, Western blots, and thin-layer chromatography (TLC) enzyme immunostaining. Type A erythrocytes had NeuGc-NeuGc-Galactose-Glucose-Ceramide ([NeuGc]2GD3) where NeuGc represents N-glycolylneuraminic acid, and NeuAc-NeuGc-GD3, where NeuAc represents N-acetylneuraminic acid, and may have [NeuGc]2 disialylparagloboside and NeuAc-NeuGc-disialylparagloboside. Type B erythrocytes only had [NeuAc]2GD3. Type AB erythrocytes had [NeuGc]2GD3, NeuAc-NeuGc-GD3, and [NeuAc]2GD3. Blood group antigens were also found on a 50-Kd membrane protein. We conclude that type B erythrocytes are characterized by [NeuAc]2GD3 as the only form of this ganglioside and the presence of NeuAc on a 50-Kd membrane protein. NeuGc is the major determinant of the A antigen; specifically, [NeuGc]2GD3 is the major glycolipid form. The A antigen is also present on a 50-Kd membrane protein.

scholarly journals Molecular characterization of cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) gene and frequency of blood types in stray cats of İzmir, Turkey

BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Hüseyin Can ◽  
Sedef Erkunt Alak ◽  
Ahmet Efe Köseoğlu ◽  
Umut Şahar ◽  
Berna Bostanbaş ◽  
...  
Keyword(s):  
Type A ◽  
Type B ◽  
Exon 2 ◽  
Blood Types ◽  
Acetylneuraminic Acid ◽  
Stray Cats ◽  
High Prevalence ◽  
Heterozygous Form ◽  
Type Ab ◽  
First Time

Abstract Background Cytidine monophospho-n-acetylneuraminic acid hydroxylase (CMAH) gene associated with blood groups in cats encodes CMAH enzyme that converts Neu5Ac to Neu5Gc. Although variations in CMAH gene of pedigree cats have been revealed, the presence/lack of them in non-pedigree stray cats is unknown. Therefore, the present study aimed to investigate the variations in CMAH gene and the quantity of Neu5Ac and Neu5Gc on erythrocytes of non-pedigree stray cats (n:12) living in İzmir, Turkey. Also, the frequency of blood types was determined in 76 stray cats including 12 cats that were used for CMAH and Neu5A/Neu5Gc analysis. Results In total, 14 SNPs were detected in 5’UTR as well as in exon 2, 4, 9, 10, 11 and 12 of CMAH gene. Among these SNPs, -495 C > T in 5’UTR was detected for the first time as heterozygous in type A and AB cats, and homozygous and heterozygous in type B cats. The remaining 13 that have been detected in previous studies were also found as homozygous or heterozygous. Both Neu5Gc and Neu5Ac were detected in type A and AB cats. In type B cats, only Neu5Ac was detected. Among two type AB cats, the level of Neu5Ac was found higher in cat carrying heterozygous form (T/C) of 1392T > C. The prevalence of type B cats (67.1 %) was higher than others. Conclusions The presence of a new SNP as well as previous SNPs indicates that more variations can be found in stray cats with a more comprehensive study in the future. Also, the high prevalence of type B cats demonstrates the possible risk of neonatal isoerythrolysis among stray cats living in İzmir, Turkey.

Ab Initio Simulations on the Carbonated Apatite Structure

2012 ◽  
Vol 529-530 ◽  
pp. 1-6 ◽  
Author(s):  
Fu Zeng Ren ◽  
Yang Leng ◽  
Xiong Lu
Keyword(s):  
Ab Initio ◽  
Type A ◽  
Hydroxyl Group ◽  
Type B ◽  
Carbonate Group ◽  
Stable Type ◽  
Carbonated Apatite ◽  
Carbonate Ions ◽  
Compensation Mechanisms ◽  
Type Ab

ab initio simulations were employed to investigate the crystal structure of carbonated apatite (CAp). Two possible sites for the carbonate ions in the apatite lattice were considered: carbonate substituting for OH-ion (type-A) and for PO43-ion (type-B). A combined type-AB substitution was also proposed and numerous possible charge compensation mechanisms were treated. The results show that the most stable type-A CAp had its carbonate triangular plane almost parallel to c-axis, making an angle of about 2° at z = 0.46. In the most stable type-B CAp structure, the nearest Ca (2) ion was replaced by a sodium ion and the carbonate group was lying almost flat inb/c-plane. Of all the models considered, mixed substitution type-AB where two carbonate ions replacing one phosphate group and one hydroxyl group shows the most stable structure.

scholarly journals ABO blood type and risk of porcine bioprosthetic aortic valve degeneration: SWEDEHEART observational cohort study

BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e029109 ◽  
Author(s):  
Michael Persson ◽  
Gustaf Edgren ◽  
Magnus Dalén ◽  
Natalie Glaser ◽  
Martin L Olsson ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cohort Study ◽  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Type A ◽  
Blood Type ◽  
Type B ◽  
Structural Valve Deterioration ◽  
Abo Blood Type

ObjectiveBlood type A antigen on porcine aortic bioprostheses might initiate an immune reaction leading to an increased frequency of structural valve deterioration in patients with blood type B or O. The aim was to analyse the association between ABO blood type and porcine bioprosthetic aortic valve degeneration.DesignObservational nationwide cohort study.SettingSwedish population-based study.ParticipantsAdult patients (n=3417) who underwent surgical aortic valve replacement and received porcine bioprosthetic aortic valves between 1995 and 2012 from the Swedish Web system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies register. The study database was enriched with information from other national registers.ExposureThe patients were categorised into type A/AB and type B/O blood groups.Primary and secondary outcome measuresPrimary outcome measure was aortic valve reoperation, and secondary outcomes were heart failure and all-cause mortality. We report risk estimates that account for the competing risk of death.ResultsIn total, 3417 patients were identified: 1724 (50.5%) with blood type A/AB and 1693 (49.5%) with blood type B/O. Both groups had similar baseline characteristics. The cumulative incidence of aortic valve reoperation was 3.4% (95% CI 2.5% to 4.4%) and 3.6% (95% CI 2.6% to 4.6%) in the type B/O and the A/AB group, respectively, at 15 years of follow-up (absolute risk difference: −0.2% (95% CI −1.5% to 1.2%)). There was no significantly increased risk for aortic valve reoperation in patients with blood type B/O compared with type A/AB (HR 0.95, 95% CI 0.62 to 1.45). There was no significant difference in absolute or relative risk of heart failure or death between the groups.ConclusionsWe found no significant association between patient blood type and clinical manifestations of structural valve deterioration following porcine aortic valve replacement. Our findings suggest that it is safe to use porcine bioprosthetic valves without consideration of ABO blood type in the recipient.Trial registration numberNCT02276950

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