New insights into the role of molecular structures on the fate and behavior of antibiotics in an osmotic membrane bioreactor

2022 ◽  
Vol 423 ◽  
pp. 127040
Author(s):  
Yu-Xiang Lu ◽  
Hai-Liang Song ◽  
Hameer Chand ◽  
You Wu ◽  
Yu-Li Yang ◽  
...  
2000 ◽  
Vol 42 (12) ◽  
pp. 173-179 ◽  
Author(s):  
S. Matsui ◽  
H. Takigami ◽  
T. Matsuda ◽  
N. Taniguchi ◽  
J. Adachi ◽  
...  

The yeast estrogen screen was applied to sewage treatment process waters to identify the presence of estrogenic activity and to investigate the fate and behavior of estrogenic substances through treatment. Hydrophobic fractions in the water phase were extracted and concentrated using C18 cartridges for the effective extraction of 17β-estradiol (E2) and other estrogen mimics. Clear dose-dependent elevation in the synthesis of β-galactosidase in the yeast screen was observed with all the samples tested, demonstrating that these samples were estrogenic. However, estrogenic activity tended to reduce during the treatment, especiallyiin the biological process. Quantification results of the yeast estrogen screen in terms of E2 equivalent were compared with actual E2 concentrations measured by an ELISA. E2 occupied 34% of the whole estrogenicity in the raw sewage, while almost 100% in the final effluent. The analyses of the sewage treatment process waters revealed that human estrogens are major causative substances in terms of estrogenic activity in sewage and its treated effluent. Although findings of possible correlation of environmental estrogens with the real impact on human health and the ecosystem are still the focus of scientific debate and investigation, proper management should be established in the sewage treatment process which receives various environmental contaminants.


2017 ◽  
Vol 25 (5) ◽  
pp. 4289-4302 ◽  
Author(s):  
Dongqing Zhang ◽  
Antoine Prandota Trzcinski ◽  
Jinxue Luo ◽  
David C. Stuckey ◽  
Soon Keat Tan

2019 ◽  
Author(s):  
Barbara Pem ◽  
Igor M Pongrac ◽  
Lea Ulm ◽  
Ivan Pavičić ◽  
Valerije Vrček ◽  
...  

Improvement in nanosafety is one of the major tasks for innovation force of nanotechology, which may be accomplished by design and development of biocompatible nanomaterials. Biocompatibility assessment demands investigation of nano-bio interactions that affect behavior and fate of nanoparticles in biological systems. Metallic nanoparticles (NPs) are particularly prone to interact with endogenous biothiols like cysteine and glutathione. This study was designed to evaluate intimate interactions between cysteine and glutathione with biomedically relevant metallic NPs, i.e. silver (AgNPs) and gold (AuNPs). Systematic and comprehensive analysis revealed that preparation of AgNPs and AuNPs in the presence of biothiols lead to stable NPs stabilized with oxidized forms of biothiols. Their biocompatibility was tested by evaluation of cell viability, ROS production, apoptosis induction and DNA damage in murine fibroblast cells (L929), while ecotoxicity was tested using aquatic model organism Daphnia magna. The toxicity of these NPs was considerably lower compared to the ionic metal forms. Comparison with data published on polymer-coated NPs evidenced that surface modification with biothiols made them safer for the environment, but more toxic for use in humans. These results represent significant contribution to the collection of knowledge on the role of biothiols on the fate and behavior of metal-based nanomaterials.


2014 ◽  
Vol 35 (2) ◽  
pp. 111-118
Author(s):  
Daniel J. Howard ◽  
Roger A. Kerin

The name similarity effect is the tendency to like people, places, and things with names similar to our own. Although many researchers have examined name similarity effects on preferences and behavior, no research to date has examined whether individual differences exist in susceptibility to those effects. This research reports the results of two experiments that examine the role of self-monitoring in moderating name similarity effects. In the first experiment, name similarity effects on brand attitude and purchase intentions were found to be stronger for respondents high, rather than low, in self-monitoring. In the second experiment, the interactive effect observed in the first study was found to be especially true in a public (vs. private) usage context. These findings are consistent with theoretical expectations of name similarity effects as an expression of egotism manifested in the image and impression management concerns of high self-monitors.


2018 ◽  
Vol 2 (1) ◽  
pp. 33
Author(s):  
Abd Rachim AF,

One of the environmental problems in urban areas is the pollution caused by garbage. The waste problem is caused by various factors such as population growth, living standards changes, lifestyles and behavior, as well as how the waste management system. This study aims to determine how the role of society to levy payments garbage in Samarinda. This research was descriptive; where the data is collected then compiled, described and analyzed used relative frequency analysis. The participation of the public to pay a "levy junk", which stated to pay 96.67%, for each month and the rates stated society cheap, moderate and fairly, respectively 46.08%, 21.21%, 21.04%. Base on the data , the role of the community to pay "levy junk" quite high.


2020 ◽  
Author(s):  
Marc Philipp Bahlke ◽  
Natnael Mogos ◽  
Jonny Proppe ◽  
Carmen Herrmann

Heisenberg exchange spin coupling between metal centers is essential for describing and understanding the electronic structure of many molecular catalysts, metalloenzymes, and molecular magnets for potential application in information technology. We explore the machine-learnability of exchange spin coupling, which has not been studied yet. We employ Gaussian process regression since it can potentially deal with small training sets (as likely associated with the rather complex molecular structures required for exploring spin coupling) and since it provides uncertainty estimates (“error bars”) along with predicted values. We compare a range of descriptors and kernels for 257 small dicopper complexes and find that a simple descriptor based on chemical intuition, consisting only of copper-bridge angles and copper-copper distances, clearly outperforms several more sophisticated descriptors when it comes to extrapolating towards larger experimentally relevant complexes. Exchange spin coupling is similarly easy to learn as the polarizability, while learning dipole moments is much harder. The strength of the sophisticated descriptors lies in their ability to linearize structure-property relationships, to the point that a simple linear ridge regression performs just as well as the kernel-based machine-learning model for our small dicopper data set. The superior extrapolation performance of the simple descriptor is unique to exchange spin coupling, reinforcing the crucial role of choosing a suitable descriptor, and highlighting the interesting question of the role of chemical intuition vs. systematic or automated selection of features for machine learning in chemistry and material science.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 796-806
Author(s):  
Sana M Kamal ◽  
Ali Al-Samydai ◽  
Rudaina Othman Yousif ◽  
Talal Aburjai

COVID-19 pandemic has spread across the world, which considered a relative of the severe acute respiratory syndrome (SARS), with possibility of transmission from animals to human and effect each of health and economic. Several preventative strategies and non-pharmaceutical interventions have been used to slow down the spread of COVID-19. The questionnaire contained 36 questions regarding the impact of COVID-19 quarantine on children`s behaviors and language have been distributed online (Google form). Data collected after asking parents about their children behavior during quarantine, among the survey completers (n=469), 42.3% were female children, and 57.7 were male children. Results showed that quarantine has an impact on children`s behaviors and language, where stress and isolationism has a higher effect, while social relations had no impact. The majority of the respondents (75.0%) had confidence that community pharmacies can play an important role in helping families in protection their children`s behaviors and language as they made the highest contact with pharmacists during quarantine. One of the main recommendations that could be applied to help parents protection and improvement their children`s behaviors and language in quarantine condition base on simple random sample opinion is increasing the role of community pharmacies inpatient counseling and especially towards children after giving courses to pharmacists in child psychology and behavior. This could be helpful to family to protect their children, from any changing in them behaviors and language in such conditions in the future if the world reface such the same problem.


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