scholarly journals Detection of possible Nipah virus infection in Rousettus leschenaultii and Pipistrellus pipistrellus bats in Maharashtra, India

2021 ◽  
Author(s):  
M.D. Gokhale ◽  
M. Sreelekshmy ◽  
A.B. Sudeep ◽  
A. Shete ◽  
R. Jain ◽  
...  
Keyword(s):  
Virus Infection ◽  
Nipah Virus ◽  
Pipistrellus Pipistrellus

Histopathologic and Immunohistochemical Characterization of Nipah Virus Infection in the Guinea Pig

2008 ◽  
Vol 45 (4) ◽  
pp. 576-585 ◽  
Author(s):  
F. J. Torres-Velez ◽  
W.-J. Shieh ◽  
P. E. Rollin ◽  
T. Morken ◽  
C. Brown ◽  
...  
Keyword(s):  
Virus Infection ◽  
Guinea Pig ◽  
Nipah Virus

scholarly journals Chloroquine Administration Does Not Prevent Nipah Virus Infection and Disease in Ferrets

2009 ◽  
Vol 83 (22) ◽  
pp. 11979-11982 ◽  
Author(s):  
Jackie Pallister ◽  
Deborah Middleton ◽  
Gary Crameri ◽  
Manabu Yamada ◽  
Reuben Klein ◽  
...  
Keyword(s):  
Virus Infection ◽  
Nipah Virus ◽  
Disease Outbreaks ◽  
Mortality Rates ◽  
Hendra Virus ◽  
Malaria Therapy ◽  
Sporadic Disease

ABSTRACT Hendra virus and Nipah virus, two zoonotic paramyxoviruses in the genus Henipavirus, have recently emerged and continue to cause sporadic disease outbreaks in humans and animals. Mortality rates of up to 75% have been reported in humans, but there are presently no clinically licensed therapeutics for treating henipavirus-induced disease. A recent report indicated that chloroquine, used in malaria therapy for over 70 years, prevented infection with Nipah virus in vitro. Chloroquine was assessed using a ferret model of lethal Nipah virus infection and found to be ineffective against Nipah virus infection in vivo.

scholarly journals Nipah virus infection among abattoir workers in Malaysia, 1998–1999

2001 ◽  
Vol 30 (5) ◽  
pp. 1017-1020 ◽  
Author(s):  
Mazrura Sahani ◽  
Umesh D Parashar ◽  
Roslinah Ali ◽  
Premalatha Das ◽  
MS Lye ◽  
...  
Keyword(s):  
Virus Infection ◽  
Nipah Virus ◽  
Abattoir Workers

scholarly journals A Mathematical Model for Nipah Virus Infection

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Assefa Denekew Zewdie ◽  
Sunita Gakkhar
Keyword(s):  
Virus Infection ◽  
Reproduction Number ◽  
Initial Conditions ◽  
Nipah Virus ◽  
Virus Transmission ◽  
Globally Asymptotically Stable ◽  
Dead Bodies ◽  
Manifold Theory ◽  
The Impact ◽  
The Given

It has been reported that unprotected contact with the dead bodies of infected individuals is a plausible way of Nipah virus transmission. An SIRD model is proposed in this paper to investigate the impact of unprotected contact with dead bodies of infected individuals before burial or cremation and their disposal rate on the dynamics of Nipah virus infection. The model is analyzed, and the reproduction number is computed. It is established that the disease-free state is globally asymptotically stable when the reproduction number is less than unity and unstable if it is greater than unity. By using the central manifold theory, we observe that the endemic equilibrium is locally stable near to unity. It is concluded that minimizing unsafe contact with the infected dead body and/or burial or cremation as fast as possible contributes positively. Further, the numerical simulations for the given choice of data and initial conditions illustrate that the endemic state is stable and the disease persists in the community when the reproduction number is greater than one.

scholarly journals Nipah virus infection: current scenario

2013 ◽  
Vol 24 (3) ◽  
pp. 398-408 ◽  
Author(s):  
D. D. Kulkarni ◽  
C. Tosh ◽  
G. Venkatesh ◽  
D. Senthil Kumar
Keyword(s):  
Virus Infection ◽  
Nipah Virus ◽  
Current Scenario

Seroprevalence of Nipah Virus Infection in Peninsular Malaysia

2020 ◽  
Vol 221 (Supplement_4) ◽  
pp. S370-S374
Author(s):  
Ming-Yen Yong ◽  
Soo-Ching Lee ◽  
Romano Ngui ◽  
Yvonne Ai-Lian Lim ◽  
Maude E Phipps ◽  
...  
Keyword(s):  
Virus Infection ◽  
Immunosorbent Assay ◽  
Indigenous Population ◽  
Nipah Virus ◽  
Peninsular Malaysia ◽  
Natural Host ◽  
Enzyme Linked Immunosorbent Assay ◽  
N Protein ◽  
Reservoir Species ◽  
Host Reservoir

Abstract Nipah virus (NiV) outbreak occurred in Malaysia in 1998. The natural host reservoir for NiV is Pteropus bats, which are commonly found throughout Malaysia. Humans become infected when NiV spills over from the reservoir species. In this study, NiV serosurveillance in Peninsular Malaysia, particularly among the indigenous population, was performed. The collected samples were tested for presence of NiV antibodies using a comparative indirect enzyme-linked immunosorbent assay based on the recombinant NiV nucleocapsid (rNiV-N) protein. We found that 10.73% of the participants recruited in this study had antibodies against rNiV-N, suggesting possible exposure to NiV.

scholarly journals Changing Contact Patterns Over Disease Progression: Nipah Virus as a Case Study

2020 ◽  
Vol 222 (3) ◽  
pp. 438-442
Author(s):  
Kyu Han Lee ◽  
Birgit Nikolay ◽  
Hossain M S Sazzad ◽  
M Jahangir Hossain ◽  
A K M Dawlat Khan ◽  
...  
Keyword(s):  
Virus Infection ◽  
Disease Progression ◽  
Disease Transmission ◽  
Nipah Virus ◽  
Risk Of Infection ◽  
Course Of Illness ◽  
Bodily Fluids ◽  
Contact Patterns

Abstract Contact patterns play a key role in disease transmission, and variation in contacts during the course of illness can influence transmission, particularly when accompanied by changes in host infectiousness. We used surveys among 1642 contacts of 94 Nipah virus case patients in Bangladesh to determine how contact patterns (physical and with bodily fluids) changed as disease progressed in severity. The number of contacts increased with severity and, for case patients who died, peaked on the day of death. Given transmission has only been observed among fatal cases of Nipah virus infection, our findings suggest that changes in contact patterns during illness contribute to risk of infection.

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