MP69-04 IDENTIFICATION OF MODIFIABLE RISK FACTORS ASSOCIATED WITH PATIENT-REPORTED ERECTILE DYSFUNCTION TO ENHANCE PATIENT HEALTH COUNSELING AND SEXUAL QUALITY OF LIFE

Aim.To assess the depressive symptoms status of chronic kidney diseases in Nantong, China, with type 2 diabetes and to identify factors associated with depressive symptoms.Methods.In this cross-sectional analytic study, 210 type 2 diabetic patients were recruited from the Second Affiliated Hospital of Nantong University. Depressive symptoms were assessed with the depression subscale of the Hospital Anxiety and Depression Scale (HAD-D). The quality of life was measured with the RAND 36-Item Health Survey (SF-36). And the independent risk factors of depressive symptoms were assessed by using a stepwise forward model of logistic regression analysis.Results.The mean age of the study subjects was 57.66 years (SD: 11.68). Approximately 21.4% of subjects reported depressive symptoms (n=45). Forward stepwise logistic regression analysis showed that female gender (P=0.010), hypertension (P=0.022), Stage IV (P=0.003), and Stage V (P<0.001) were significant risk factors for depressive symptoms. The quality of life of individuals with HAD-D score <11 was significantly better compared with individuals with HAD-D score ≥ 11.Conclusions.These results indicate that clinicians should be aware that female patients with chronic kidney diseases with T2DM in their late stage with hypertension are at a marked increased risk of depressive symptoms. Providing optimal care for the psychological health of this population is vital.

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Prevalence and factors associated with erectile dysfunction among adult men in Moshi municipal, Tanzania: community-based study

10.21203/rs.2.22030/v1 ◽

2020 ◽

Author(s):

KENAN BOSCO NYALILE ◽

Emmanuel HP Mushi ◽

Epiphania Moshi ◽

Beatrice J. Leyaro ◽

Sia E Msuya ◽

...

Keyword(s):

Quality Of Life ◽

Erectile Dysfunction ◽

Lifestyle Modification ◽

Negative Impact ◽

Screening Program ◽

Community Based ◽

Cross Sectional ◽

Factors Associated ◽

Adult Men

Abstract Background: Erectile dysfunction (ED) has a negative impact on ones’ relationships with poor quality of life as inevitable result. Men’s sexual health has been forgotten in most developing countries and therefore the burden of ED and associated risk factors are not known in these settings. This study aimed to determine the prevalence and factors associated with erectile dysfunction among adult men in Moshi municipality, northern Tanzania. Methodology: A community based cross-sectional study was conducted in July 2019. Multi stage sampling technique was used to enroll men aged 18 years and above infour wards of Moshi municipality. The 5-item version of the International Index of Erectile Function (IIEF-5) scale was used to assess erectile dysfunction. Multivariate logistic regression was done to get factors associated with ED. Results: The mean age of the 381 men was 39.6 (SD ±16.8) years. Theoverall prevalence of ED on this study was 29.7%. The severity of ED among study participants was 13.4 % (51), 9.7 % (37), 3.7 % (14), 2.9% (11) participants had mild, mild to moderate, moderate and severe erectile dysfunction respectively. Age, tobacco use, overweight, hypertension and diabetes all showed significance association with ED. However, in multivariate logistic analysis only age ≥40 years and hypertension remain statistically significant associated with ED [(OR 5.2, 95% CI 2.68-10.21, P<0.001), (OR 11.5, 95% CI 5.8-22.76, P<0.001) and (OR 2.5, 95% CI 1.06-5.86, P=0.035) ] respectively. Conclusion: About one in three men in Moshi municipal had ED. High prevalence of ED among hypertensive individuals suggest a need to establish ED screening program during their routine clinic for early detection and treatment. Furthermore, education should be given on lifestyle modification to prevent hypertension and diabetes in the community. The outcome will be improvement of patient’s quality of life. Key words: Erectile dysfunction, Diabetes mellitus, Hypertension, Physical activities, Prevalence, Predictors, Tanzania

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Risk factors associated with peripheral neuropathy among diabetic individuals: a case control study

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20210236 ◽

2021 ◽

Vol 8 (2) ◽

pp. 768

Author(s):

Christa Kingston ◽

Aravindan J. ◽

Srikumar Walsalam

Keyword(s):

Quality Of Life ◽

Risk Factors ◽

Diabetic Neuropathy ◽

Case Control Study ◽

Case Control ◽

Diabetic Patients ◽

Factors Associated ◽

History Of ◽

Control Study

Background: Diabetic neuropathy is one among the most common complication in diabetes mellitus. Diabetic peripheral neuropathy hinders the quality of life causing morbidity and mortality. The purpose of this study was to find the risk factors associated with diabetic neuropathy.Methods: This case control study involved 100 diabetic patients attending the Dohnavur fellowship hospital, Dohnavur from October 2019 to March 2020. Sociodemographic profile and diabetic characteristics of the study group were obtained and analysed. Diagnosis of Diabetic Neuropathy was done by using the diagnostic method proposed by American Diabetic Association.Results: Of the total study population with mean age 59.43 years, 63% had family history of diabetes. Almost 70% had poor diabetic control. Statistically significant relationships were found between neuropathy and duration of diabetes, glycaemic control, history of hypertension, monofilament test and pinprick sensation.Conclusions: In this study, glycemic control, dyslipidemia and hypertension were modifiable risk factors for diabetic neuropathy. Early interventional programs to sensitize diabetics on these factors could improve the quality of life of Diabetic patients.

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Long-Term Patient Satisfaction and Quality of Life After Breast-Conserving Therapy: A Prospective Study Using the BREAST-Q

Annals of Surgical Oncology ◽

10.1245/s10434-021-10377-4 ◽

2021 ◽

Author(s):

Ilona Stolpner ◽

Jörg Heil ◽

Fabian Riedel ◽

Markus Wallwiener ◽

Benedikt Schäfgen ◽

...

Keyword(s):

Quality Of Life ◽

Risk Factors ◽

Patient Satisfaction ◽

Repeated Measures ◽

Aesthetic Surgery ◽

Well Being ◽

Breast Conserving Therapy ◽

Patient Reported

Abstract Background Poor patient-reported satisfaction after breast-conserving therapy (BCT) has been associated with impaired health-related quality of life (HRQOL) and subsequent depression in retrospective analysis. This prospective cohort study aimed to assess the HRQOL of patients who have undergone BCT using the BREAST-Q, and to identify clinical risk factors for lower patient satisfaction. Methods Patients with primary breast cancer undergoing BCT were asked to complete the BREAST-Q preoperatively (T1) for baseline evaluation, then 3 to 4 weeks postoperatively (T2), and finally 1 year after surgery (T3). Clinicopathologic data were extracted from the patients’ charts. Repeated measures analysis of variance (ANOVA) was used to determine significant differences in mean satisfaction and well-being levels among the test intervals. Multiple linear regression was used to evaluate risk factors for lower satisfaction. Results The study enrolled 250 patients. The lowest baseline BREAST-Q score was reported for “satisfaction with breast” (mean, 61 ± 19), but this increased postoperatively (mean, 66 ± 18) and was maintained at the 1 year follow-up evaluation (mean, 67 ± 21). “Physical well-being” decreased from T1 (mean, 82 ± 17) to T2 (mean, 28 ± 13) and did not recover much by T3 (mean, 33 ± 13), being the lowest BREAST-Q score postoperatively and in the 1-year follow-up evaluation. In multiple regression, baseline psychosocial well-being, body mass index (BMI), and type of incision were risk factors for lower “satisfaction with breasts.” Conclusion Both the aesthetic/surgery-related and psychological aspects are equally important with regard to “satisfaction with breasts” after BCT. The data could serve as the benchmark for future studies.

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Vardenafil improves sexual quality of life (QOL) in both men with erectile dysfunction and their partners,

Inpharma Weekly ◽

10.2165/00128413-200514800-00029 ◽

2005 ◽

Vol &NA; (1480-1481) ◽

pp. 15

Author(s):

&NA;

Keyword(s):

Quality Of Life ◽

Erectile Dysfunction ◽

Sexual Quality Of Life

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Hydroxycarbamide Plus Aspirin Versus Aspirin Alone in Patients With Essential Thrombocythemia Age 40 to 59 Years Without High-Risk Features

Journal of Clinical Oncology ◽

10.1200/jco.2018.78.8414 ◽

2018 ◽

Vol 36 (34) ◽

pp. 3361-3369 ◽

Cited By ~ 10

Author(s):

Anna L. Godfrey ◽

Peter J. Campbell ◽

Cathy MacLean ◽

Georgina Buck ◽

Julia Cook ◽

...

Keyword(s):

Quality Of Life ◽

Risk Factors ◽

Platelet Count ◽

High Risk ◽

Vascular Events ◽

End Point ◽

High Risk Factors ◽

Patient Reported

Purpose Cytoreductive therapy is beneficial in patients with essential thrombocythemia (ET) at high risk of thrombosis. However, its value in those lacking high-risk features remains unknown. This open-label, randomized trial compared hydroxycarbamide plus aspirin with aspirin alone in patients with ET age 40 to 59 years and without high-risk factors or extreme thrombocytosis. Patients and Methods Patients were age 40 to 59 years and lacked a history of ischemia, thrombosis, embolism, hemorrhage, extreme thrombocytosis (platelet count ≥ 1,500 × 109/L), hypertension, or diabetes requiring therapy. In all, 382 patients were randomly assigned 1:1 to hydroxycarbamide plus aspirin or aspirin alone. The composite primary end point was time to arterial or venous thrombosis, serious hemorrhage, or death from vascular causes. Secondary end points were time to first arterial or venous thrombosis, first serious hemorrhage, death, incidence of transformation, and patient-reported quality of life. Results After a median follow-up of 73 months and a total follow-up of 2,373 patient-years, there was no significant difference between the arms in the likelihood of patients reaching the primary end point (hazard ratio, 0.98; 95% CI, 0.42 to 2.25; P = 1.0). The incidence of significant vascular events was low, at 0.93 per 100 patient-years (95% CI, 0.61 to 1.41). There were also no differences in overall survival; in the composite end point of transformation to myelofibrosis, acute myeloid leukemia, or myelodysplasia; in adverse events; or in patient-reported quality of life. Conclusion In patients with ET age 40 to 59 years and lacking high-risk factors for thrombosis or extreme thrombocytosis, preemptive addition of hydroxycarbamide to aspirin did not reduce vascular events, myelofibrotic transformation, or leukemic transformation. Patients age 40 to 59 years without other clinical indications for treatment (such as previous thrombosis or hemorrhage) who have a platelet count < 1,500 × 109/L should not receive cytoreductive therapy.

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