scholarly journals Differential anti-inflammatory biomarkers of the desert truffles Terfezia claveryi and Tirmania nivea revealed via UPLC-QqQ-MS-based metabolomics combined to chemometrics

LWT ◽  
2021 ◽  
pp. 111965
Author(s):  
Reham S. Darwish ◽  
Eman Shawky ◽  
Khallad M. Nassar ◽  
Ramez M. Rashad ElSayed ◽  
Dalia E. Hussein ◽  
...  
Keyword(s):  
Inflammatory Biomarkers ◽  
Anti Inflammatory ◽  
Terfezia Claveryi ◽  
Desert Truffles

Inflammatory Biomarkers in Atrial Fibrillation

2019 ◽  
Vol 26 (5) ◽  
pp. 837-854 ◽  
Author(s):  
Effimia Zacharia ◽  
Nikolaos Papageorgiou ◽  
Adam Ioannou ◽  
Gerasimos Siasos ◽  
Spyridon Papaioannou ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Plasma Levels ◽  
Large Scale ◽  
Inflammatory Biomarkers ◽  
Inflammatory Pathways ◽  
Inflammatory State ◽  
Anti Inflammatory ◽  
Underlying Mechanisms

During the last few years, a significant number of studies have attempted to clarify the underlying mechanisms that lead to the presentation of atrial fibrillation (AF). Inflammation is a key component of the pathophysiological processes that lead to the development of AF; the amplification of inflammatory pathways triggers AF, and, in tandem, AF increases the inflammatory state. Indeed, the plasma levels of several inflammatory biomarkers are elevated in patients with AF. In addition, the levels of specific inflammatory biomarkers may provide information regarding to the AF duration. Several small studies have assessed the role of anti-inflammatory treatment in atrial fibrillation but the results have been contradictory. Large-scale studies are needed to evaluate the role of inflammation in AF and whether anti-inflammatory medications should be routinely administered to patients with AF.

scholarly journals The 3-Year Effect of the Mediterranean Diet Intervention on Inflammatory Biomarkers Related to Cardiovascular Disease

Biomedicines ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 862
Author(s):  
Mireia Urpi-Sarda ◽  
Rosa Casas ◽  
Emilio Sacanella ◽  
Dolores Corella ◽  
Cristina Andrés-Lacueva ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Mediterranean Diet ◽  
Virgin Olive Oil ◽  
Extra Virgin Olive Oil ◽  
Inflammatory Biomarkers ◽  
Year Effect ◽  
Tnf Α ◽  
The Mediterranean ◽  
Anti Inflammatory

The intervention with the Mediterranean diet (MD) pattern has evidenced short-term anti-inflammatory effects, but little is known about its long-term anti-inflammatory properties at molecular level. This study aims to investigate the 3-year effect of MD interventions compared to low-fat diet (LFD) on changes on inflammatory biomarkers related to atherosclerosis in a free-living population with a high-risk of cardiovascular disease (CD). Participants (n = 285) in the PREDIMED trial were randomly assigned into three intervention groups: MD with extra-virgin olive oil (EVOO) or MD-Nuts, and a LFD. Fourteen plasma inflammatory biomarkers were determined by Luminex assays. An additional pilot study of gene expression (GE) was determined by RT-PCR in 35 participants. After 3 years, both MDs showed a significant reduction in the plasma levels of IL-1β, IL-6, IL-8, TNF-α, IFN-γ, hs-CRP, MCP-1, MIP-1β, RANTES, and ENA78 (p < 0.05; all). The decreased levels of IL-1β, IL-6, IL-8, and TNF-α after MD significantly differed from those in the LFD (p < 0.05). No significant changes were observed at the gene level after MD interventions, however, the GE of CXCR2 and CXCR3 tended to increase in the control LFD group (p = 0.09). This study supports the implementation of MD as a healthy long-term dietary pattern in the prevention of CD in populations at high cardiovascular risk.

scholarly journals Seasonal dynamics of the phenolic constituents of the cones and leaves of oriental Thuja (Platycladus orientalis L.) reveal their anti-inflammatory biomarkers

RSC Advances ◽  
2021 ◽  
Vol 11 (40) ◽  
pp. 24624-24635
Author(s):  
Reham S. Darwish ◽  
Hala M. Hammoda ◽  
Doaa A. Ghareeb ◽  
Ali S. A. Abdelhamid ◽  
Fathallah M. Harraz ◽  
...  
Keyword(s):  
Seasonal Dynamics ◽  
Inflammatory Biomarkers ◽  
Inflammatory Activity ◽  
Platycladus Orientalis ◽  
Phenolic Constituents ◽  
Anti Inflammatory

In this study, the seasonal dynamics of the flavonoids in the cones and leaves of oriental Thuja (Platycladus orientalis L. Franco) as well as the in vitro anti-inflammatory activity of their extracts were investigated.

In Inflamation Dietary Inflammatory Index and the Role of Different Diet Types

2020 ◽  
pp. 169-201
Author(s):  
Ramazan Mert Atan ◽  
Uğur Günşen
Keyword(s):  
Chronic Diseases ◽  
Inflammatory Cytokines ◽  
Scientific Evidence ◽  
Inflammatory Biomarkers ◽  
Dietary Inflammatory Index ◽  
Food Groups ◽  
Negative Effects ◽  
Inflammatory Index ◽  
Anti Inflammatory

Inflammation usually occurs as a result of imbalances between pro-inflammatory and anti-inflammatory cytokines. Diet is one of the factors that play a role in their development and prevent them from developing. Therefore, it is important to determine the pro- and anti-inflammatory properties of foods. Diet is an important and modifiable determinant of chronic diseases. There is a lot of scientific evidence to support the fact that foods consumed have positive and negative effects on individuals' health. In addition to being effective whole of diet, it is seen that the food groups contained in the diet affect the inflammatory biomarkers separately. This section provides information about dietary inflammatory index (DII) and diets that are effective on inflammation.

Effet des conditions de culture sur la mycorhization de l’Helianthemum guttatum par trois espèces de terfez des genres Terfezia et Tirmania d'Algérie

1992 ◽  
Vol 70 (12) ◽  
pp. 2453-2460 ◽  
Author(s):  
Zohra Fortas ◽  
Gérard Chevalier
Keyword(s):  
Key Words ◽  
Nutritive Solution ◽  
Mycorrhizal Synthesis ◽  
Terfezia Arenaria ◽  
Axenic Conditions ◽  
Terfezia Claveryi ◽  
Desert Truffles

Three species of edible desert truffles, Terfezia arenaria, Terfezia claveryi, and Tirmania pinoyi associated with Helianthemum guttatum in Algeria were examined in this study. The mycorrhizal synthesis between the three species of desert truffles and Helianthemum guttatum was carried out with two different methods: (i) under axenic conditions on perlite permeated by a nutritive solution, by inoculating the seedlings with mycelial fragments; (ii) under gnotoxenic conditions on natural substrates, by inoculating plants with spore suspensions. The method of synthesis did not have any influence on the type of mycorrhizae. The desert truffles formed two types of mycorrhizae according to the fertility of the substrate: ectomycorrhizae without sheath, in the phosphorus rich substrates, or ectendomycorrhizae, also without sheath, in the phosphorus deficient substrates. Primordial ascomata were obtained in the syntheses involving polysporous inocula. Key words: ectomycorrhizae, ectendomycorrhizae, Helianthemum guttatum, Terfezia, Tirmania.

Olive Oil-related Anti-inflammatory Effects on Atherosclerosis: Potential Clinical Implications

2017 ◽  
Vol 18 (1) ◽  
pp. 51-62 ◽  
Author(s):  
Tanakal Wongwarawipat ◽  
Nikolaos Papageorgiou ◽  
Dimitrios Bertsias ◽  
Gerasimos Siasos ◽  
Dimitris Tousoulis
Keyword(s):  
Secondary Prevention ◽  
Randomized Controlled Trials ◽  
Olive Oil ◽  
Inflammatory Biomarkers ◽  
Cochrane Library ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Incidence And Mortality ◽  
Cardioprotective Effects ◽  
Anti Inflammatory

Background and Objective: Atherosclerosis is characterized by a chronic low-grade inflammatory process which can result in atherothrombosis and a number of cardiovascular diseases (CVD). It is believed to be caused by multiple processes that involve inflammation and immunity. Mediterranean Diet (MedD) has been discovered to possess anti-inflammatory properties and associated with a reduction in the CVD risk and mortality. Its main component, extra-virgin olive oil (EVOO), is believed to be largely responsible for these effects and therefore, has been investigated in various studies. The present review article aims to summarize the available literature on the antiinflammatory and cardio-protective effects of EVOO. Methods: A search based on the key concepts “olive oil”, “atherosclerosis”, “inflammation” and “cardiovascular disease” was performed to retrieve relevant studies and articles on the association between the consumption of EVOO and the levels of inflammatory biomarkers as well as CVD incidence and mortality from online databases; Pubmed, Embase and Cochrane Library. Results: Consumption of EVOO is associated with a reduction in inflammatory biomarkers and molecules implicated in atherosclerosis as well as CVD incidence and mortality as well as other complications such as heart failure and atrial fibrillation. Moreover, these anti-inflammatory and cardioprotective effects of EVOO are mostly attributable to its high content of polyphenol molecules. Conclusion: Currently available evidence supports the anti-inflammatory and cardio-protective roles of EVOO. However, there is limited amount of available randomized controlled trials especially lacking those investigating the use of EVOO as secondary prevention, heterogeneity of study design, limited generalization to wide population groups, and inability to determine the minimum intake of EVOO required to clinically achieve the anti-inflammatory and cardioprotective effects. Therefore, more highquality randomized controlled trials still need to be carried out to overcome these challenges to further assess the health benefits of EVOO consumption and potentially translate it into clinical practice as primary or secondary prevention of atherosclerosis-related conditions.

scholarly journals Cytokine response during non-cerebral and cerebral malaria: evidence of a failure to control inflammation as a cause of death in African adults

2016 ◽  
Author(s):  
Yakhya Dieye ◽  
Babacar Mbengue ◽  
Shobha Dagamajalu ◽  
Mouhamadou M Fall ◽  
Mun Fai Loke ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Growth Factors ◽  
Cerebral Malaria ◽  
Inflammatory Cytokines ◽  
Serum Levels ◽  
Organ Damage ◽  
Inflammatory Biomarkers ◽  
Immune Mediators ◽  
Anti Inflammatory ◽  
Almost All

Background. With 214 million cases and 438,000 deaths in 2015, malaria remains one of the deadliest infectious diseases in tropical countries. Several species of the protozoan Plasmodium cause malaria. However, almost all the fatalities are due to Plasmodium falciparum, a species responsible for the severest cases including cerebral malaria. Immune response to Plasmodium falciparum infection is mediated by the production of pro-inflammatory cytokines, chemokines and growth factors whose actions are crucial for the control of the parasites. Following this response, the induction of anti-inflammatory immune mediators downregulates the inflammation thus preventing its adverse effects such as damages to various organs and death. Methods. We performed a retrospective, nonprobability sampling study using clinical data and sera samples from patients, mainly adults, suffering of non-cerebral or cerebral malaria in Dakar, Sénégal. Healthy individuals residing in the same area were included as controls. We measured the serum levels of 29 biomarkers including growth factors, chemokines, inflammatory and anti-inflammatory cytokines. Results. We found an induction of both pro- and anti-inflammatory immune mediators during malaria. The levels of pro-inflammatory biomarkers were higher in the cerebral malaria than in the non-cerebral malaria patients. In contrast, the concentrations of anti-inflammatory cytokines were comparable in these two groups or lower in CM patients. Additionally, four pro-inflammatory biomarkers were significantly increased in the deceased of cerebral malaria compared to the survivors. Regarding organ damage, kidney failure was significantly associated with death in adults suffering of cerebral malaria. Conclusions. Our results suggest that a poorly controlled inflammatory response determines a bad outcome in African adults suffering of cerebral malaria.

Sign in / Sign up

Export Citation Format

Share Document