scholarly journals Corrigendum to “The relationship between Chlamydia pneumoniae infection and CD4/CD8 ratio, lymphocyte subsets in middle-aged and elderly individuals” [Microb. Pathog. 149 (2020) 104541]

2021 ◽  
pp. 105090
Author(s):  
Xiao-Qing Quan ◽  
Chang Xu ◽  
Run-Chang Wang ◽  
Cun-Tai Zhang ◽  
Qing Zhang ◽  
...  
Keyword(s):  
Chlamydia Pneumoniae ◽  
Lymphocyte Subsets ◽  
Middle Aged ◽  
Elderly Individuals ◽  
The Relationship

The relationship between Chlamydia pneumoniae infection and CD4/CD8 ratio, lymphocyte subsets in middle-aged and elderly individuals

2020 ◽  
Vol 149 ◽  
pp. 104541
Author(s):  
Xiao-Qing Quan ◽  
Chang Xu ◽  
Run-Chang Wang ◽  
Cun-Tai Zhang ◽  
Qing Zhang ◽  
...  
Keyword(s):  
Chlamydia Pneumoniae ◽  
Lymphocyte Subsets ◽  
Middle Aged ◽  
Elderly Individuals ◽  
The Relationship

scholarly journals Role of Socioeconomic Status in Hypertension among Chinese Middle-Aged and Elderly Individuals

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Xinyi Wu ◽  
Zhonghua Wang
Keyword(s):  
Socioeconomic Status ◽  
Logistic Regression ◽  
Concentration Index ◽  
Health Concern ◽  
Multivariate Logistic Regression ◽  
Middle Aged ◽  
Elderly Individuals ◽  
Income Groups ◽  
The Relationship

Hypertension is an important global health concern. The relationship between hypertension and socioeconomic status (SES) has been extensively studied. However, the role of SES in hypertension is still controversial, and this kind of study is sorely lacking among Chinese middle-aged and elderly individuals. The data of this study come from the China Health and Retirement Longitudinal Survey (CHARLS) released in May 2017. A total of 21,126 people from all around China, with ages older than 45 years, were enrolled in the questionnaire survey. Hypertension was determined according to the entry in CHARLS (“Do you have doctor-diagnosed hypertension?”), and 17,676 people responded to this entry. The basic demographic and SES information were collected. Multivariate logistic regression was used to evaluate the risk factors of hypertension. Concentration index was used to measure inequality of hypertension incidence. Among the investigated middle-aged and elderly individuals, 5,177/17,676 (29.3%) had doctor-diagnosed hypertension. Multivariate logistic regression implied that individuals older than 55 years (OR 1.436, 95% CI 1.085–1.900 for age interval of 55–64 years; OR 2.032, 95% CI 1.455–2.839 for age interval of 65–74 years; OR 1.672, 95% CI 1.031–2.714 for age interval of older than 75 years), male (OR 0.038, 95% CI 0.595–0.986), overweight (OR 2.47, 95% CI 1.462–4.183), and diabetes (OR 3.159, 95% CI 2.129–4.687) were associated with hypertension. For society support, individuals in the lowest quintile were more likely to suffer hypertension. Concentration index results suggested that different income groups did not show inequality on hypertension incidence. Elder age, male, overweight, diabetes, and poor society support were suggested to be associated with hypertension incidence among middle-aged and elderly individuals in China. Our study provides implications for controlling and managing hypertension.

scholarly journals Circulating levels of IGF1 are associated with muscle strength in middle-aged- and oldest-old women

2011 ◽  
Vol 164 (2) ◽  
pp. 189-196 ◽  
Author(s):  
Diana G Taekema ◽  
Carolina H Y Ling ◽  
Gerard Jan Blauw ◽  
Carel G Meskers ◽  
Rudi G J Westendorp ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Physical Performance ◽  
Handgrip Strength ◽  
Oldest Old ◽  
Muscle Growth ◽  
Serum Levels ◽  
Middle Aged ◽  
Cross Sectional ◽  
The Relationship ◽  
Circulating Levels

ObjectiveIn aging populations, poor handgrip strength has been associated with physical disability and mortality. IGF1 is an important mediator of muscle growth and regeneration affecting muscle function. We studied the relationship between circulating levels of IGF1, its binding protein 3 (IGFBP3), and handgrip strength and physical performance in middle-aged- and oldest-old subjects.DesignCross-sectional analysis in two different cohorts composed of middle-aged- (n=672, mean 63.9±6.7 years) and oldest-old subjects (n=272, all 89 years).MethodsHandgrip strength, functional performance and ability, and serum levels of IGF1 and IGFBP3 were measured in all subjects and analyzed by linear regression for men and women separately.ResultsIGF1 and IGFBP3 levels declined with chronological age and were positively associated with handgrip strength in middle-aged- and oldest-old women (both, P<0.05), but not in men of either age group. Furthermore, higher serum levels of IGF1 were associated with slower walking speed in oldest-old men (P=0.012), and serum levels of IGFBP3 were positively associated with activities of daily living in the oldest-old women (P=0.002).ConclusionThe significant relationship between IGF1 levels and muscle strength found in women but not in men suggests a gender-specific influence of IGF1 on muscle strength. Further studies are necessary to test the relationship with physical performance.

scholarly journals Modifiers of cognitive function and brain structure in middle-aged and elderly individuals with type 2 diabetes mellitus

2009 ◽  
Vol 1280 ◽  
pp. 186-194 ◽  
Author(s):  
Hannah Bruehl ◽  
Oliver T. Wolf ◽  
Victoria Sweat ◽  
Aziz Tirsi ◽  
Stephen Richardson ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cognitive Function ◽  
Brain Structure ◽  
Middle Aged ◽  
Elderly Individuals

Effect of older adults in the family on the sandwich generation's pursuit of entrepreneurship: evidence from China

2021 ◽  
pp. 1-20
Author(s):  
Yiwei Liu ◽  
Wenjing Wang ◽  
Zhen Cong ◽  
Zhirui Chen
Keyword(s):  
Older Adults ◽  
Family Members ◽  
Mediating Effect ◽  
Entrepreneurial Activity ◽  
Basic Unit ◽  
Instrumental Support ◽  
Middle Aged ◽  
Social Wellbeing ◽  
The Relationship ◽  
Elderly Family

Abstract Household entrepreneurship is a basic unit of entrepreneurial activity, and a crucial aspect of connecting personal and social wellbeing. This study examines the relationship between the proportion of elderly family members and household entrepreneurship. This study also assesses the mediating effect of the middle-aged generation's support to their parents and the moderating effect of the parents’ support with respect to the proportion of elderly family members and entrepreneurship. We use data from the China Family Panel Studies. We adopt the instrumental variable method to deal with endogeneity, robustness and credibility of the estimation results. The results show that a higher proportion of elderly family members impedes household entrepreneurship. Moreover, the financial and instrumental support provided by the middle-aged generation to their parents significantly mediates the relationship between the proportion of elderly family members and household entrepreneurship. In turn, parents’ financial support to the middle-aged generation moderates the focal relationship; however, parents’ instrumental support does not moderate the focal relationship. These findings emphasise the need to develop a comprehensive social security network for older adults that will indirectly promote household entrepreneurship, and improve personal and social wellbeing.

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