Construction and evaluation of tumor nucleus-targeting nanocomposite for cancer dual-mode imaging – Guiding photodynamic therapy/photothermal therapy

Photodynamic therapy (PDT) and photothermal therapy (PTT) are well-developed light therapy methods for cancer; however, both have a few areas that need improvement.

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Organic dots (O-dots) for theranostic applications: preparation and surface engineering

RSC Advances ◽

10.1039/d0ra08041a ◽

2021 ◽

Vol 11 (4) ◽

pp. 2253-2291

Author(s):

Amin Shiralizadeh Dezfuli ◽

Elmira Kohan ◽

Sepand Tehrani Fateh ◽

Neda Alimirzaei ◽

Hamidreza Arzaghi ◽

...

Keyword(s):

Quantum Dots ◽

Photodynamic Therapy ◽

Photothermal Therapy ◽

Biomedical Applications ◽

Surface Engineering ◽

Graphene Quantum Dots ◽

Carbon Quantum Dots ◽

Cargo Delivery ◽

Bio Imaging ◽

Theranostic Applications

Organic dots is a term used to represent materials including graphene quantum dots and carbon quantum dots because they rely on the presence of other atoms (O, H, and N) for their photoluminescence or fluorescence properties. Cargo delivery, bio-imaging, photodynamic therapy and photothermal therapy are major biomedical applications of organic dots.

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Chlorin e6-Coated Superparamagnetic Iron Oxide Nanoparticle (SPION) Nanoclusters as a Theranostic Agent for Dual-Mode Imaging and Photodynamic Therapy

Scientific Reports ◽

10.1038/s41598-019-39036-1 ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 23

Author(s):

Ahmad Amirshaghaghi ◽

Lesan Yan ◽

Joann Miller ◽

Yonathan Daniel ◽

Joel M. Stein ◽

...

Keyword(s):

Photodynamic Therapy ◽

Iron Oxide ◽

Superparamagnetic Iron Oxide ◽

Chlorin E6 ◽

Iron Oxide Nanoparticle ◽

Dual Mode ◽

Theranostic Agent ◽

Oxide Nanoparticle ◽

Superparamagnetic Iron Oxide Nanoparticle

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Design and Synthesis of a Lead Sulfide Based Nanotheranostic Agent for Computer Tomography/Magnetic Resonance Dual-Mode-Bioimaging-Guided Photothermal Therapy

ACS Applied Nano Materials ◽

10.1021/acsanm.8b00359 ◽

2018 ◽

Vol 1 (5) ◽

pp. 2294-2305 ◽

Cited By ~ 14

Author(s):

Yibiao Zou ◽

Honglin Jin ◽

Fei Sun ◽

Xiaomeng Dai ◽

Zushun Xu ◽

...

Keyword(s):

Magnetic Resonance ◽

Computer Tomography ◽

Lead Sulfide ◽

Photothermal Therapy ◽

Dual Mode ◽

Design And Synthesis

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Phototherapy and multimodal imaging of cancers based on perfluorocarbon nanomaterials

Journal of Materials Chemistry B ◽

10.1039/d1tb00554e ◽

2021 ◽

Author(s):

Zhaoguo Han ◽

xianshuang tu ◽

Lina Qiao ◽

Yige Sun ◽

Zibo Li ◽

...

Keyword(s):

Photodynamic Therapy ◽

Side Effects ◽

Cancer Treatment ◽

Photothermal Therapy ◽

Multimodal Imaging

Phototherapy, such as photodynamic therapy (PDT) and photothermal therapy (PTT) possesses unique characteristics of non-invasiveness and minimal side effects in cancer treatment, compared with conventional therapies. However, the ubiquitous tumor...

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Photo-Based Nanomedicines Using Polymeric Systems in the Field of Cancer Imaging and Therapy

Biomedicines ◽

10.3390/biomedicines8120618 ◽

2020 ◽

Vol 8 (12) ◽

pp. 618

Author(s):

Patihul Husni ◽

Yuseon Shin ◽

Jae Chang Kim ◽

Kioh Kang ◽

Eun Seong Lee ◽

...

Keyword(s):

Photodynamic Therapy ◽

Optical Imaging ◽

Photothermal Therapy ◽

Cancer Imaging ◽

Polymeric Systems ◽

Therapeutic Applications ◽

Shed Light

The use of photo-based nanomedicine in imaging and therapy has grown rapidly. The property of light in converting its energy into different forms has been exploited in the fields of optical imaging (OI) and phototherapy (PT) for diagnostic and therapeutic applications. The development of nanotechnology offers numerous advantages to overcome the challenges of OI and PT. Accordingly, in this review, we shed light on common photosensitive agents (PSAs) used in OI and PT; these include fluorescent and bioluminescent PSAs for OI or PT agents for photodynamic therapy (PDT) and photothermal therapy (PTT). We also describe photo-based nanotechnology systems that can be used in photo-based diagnostics and therapies by using various polymeric systems.

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