scholarly journals Organic dots (O-dots) for theranostic applications: preparation and surface engineering

RSC Advances ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 2253-2291
Author(s):  
Amin Shiralizadeh Dezfuli ◽  
Elmira Kohan ◽  
Sepand Tehrani Fateh ◽  
Neda Alimirzaei ◽  
Hamidreza Arzaghi ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Photodynamic Therapy ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Surface Engineering ◽  
Graphene Quantum Dots ◽  
Carbon Quantum Dots ◽  
Cargo Delivery ◽  
Bio Imaging ◽  
Theranostic Applications

Organic dots is a term used to represent materials including graphene quantum dots and carbon quantum dots because they rely on the presence of other atoms (O, H, and N) for their photoluminescence or fluorescence properties. Cargo delivery, bio-imaging, photodynamic therapy and photothermal therapy are major biomedical applications of organic dots.

Synthesis of carbon quantum dots from cabbage with down- and up-conversion photoluminescence properties: excellent imaging agent for biomedical applications

2015 ◽  
Vol 17 (7) ◽  
pp. 3791-3797 ◽  
Author(s):  
Al-Mahmnur Alam ◽  
Byung-Yong Park ◽  
Zafar Khan Ghouri ◽  
Mira Park ◽  
Hak-Yong Kim
Keyword(s):  
Quantum Dots ◽  
Biomedical Applications ◽  
Carbon Quantum Dots ◽  
Imaging Agent ◽  
Photoluminescence Properties ◽  
Bio Imaging

The synthesis of luminescent and biocompatible carbon quantum dots is demonstrated from cabbage, a new carbonaceous biomaterial, for bio-imaging.

scholarly journals Multifunctional graphene quantum dots for combined photothermal and photodynamic therapy coupled with cancer cell tracking applications

RSC Advances ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. 5251-5261 ◽  
Author(s):  
Mukeshchand Thakur ◽  
Mukesh Kumar Kumawat ◽  
Rohit Srivastava
Keyword(s):  
Quantum Dots ◽  
Photodynamic Therapy ◽  
Carbon Source ◽  
Cancer Cell ◽  
Biomedical Applications ◽  
Cell Tracking ◽  
Graphene Quantum Dots ◽  
Green Factory ◽  
Fig Tree

An Indian fig tree serves as a green factory by providing withered leaves as a carbon source for graphene quantum dots synthesis. The quantum dots are multi-functional and have tremendous theranostic biomedical applications.

scholarly journals N-Doped Carbon Quantum Dots as Fluorescent Bioimaging Agents

Crystals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 789
Author(s):  
Shih-Fu Ou ◽  
Ya-Yun Zheng ◽  
Sin-Jen Lee ◽  
Shyi-Tien Chen ◽  
Chien-Hui Wu ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Carbon Nanomaterials ◽  
Graphene Quantum Dots ◽  
Carbon Quantum Dots ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Negative ◽  
Gram Positive Bacteria ◽  
Fluorescence Characteristics ◽  
And Staphylococcus Aureus

Graphene quantum dots, carbon nanomaterials with excellent fluorescence characteristics, are advantageous for use in biological systems owing to their small size, non-toxicity, and biocompatibility. We used the hydrothermal method to prepare functional N-doped carbon quantum dots (N-CQDs) from 1,3,6-trinitropyrene and analyzed their ability to fluorescently stain various bacteria. Our results showed that N-CQDs stain the cell septa and membrane of the Gram-negative bacteria Escherichia coli, Salmonellaenteritidis, and Vibrio parahaemolyticus and the Gram-positive bacteria Bacillus subtilis, Listeria monocytogenes, and Staphylococcus aureus. The optimal concentration of N-CQDs was approximately 500 ppm for Gram-negative bacteria and 1000 ppm for Gram-positive bacteria, and the exposure times varied with bacteria. N-Doped carbon quantum dots have better light stability and higher photobleaching resistance than the commercially available FM4-64. When excited at two different wavelengths, N-CQDs can emit light of both red and green wavelengths, making them ideal for bioimaging. They can also specifically stain Gram-positive and Gram-negative bacterial cell membranes. We developed an inexpensive, relatively easy, and bio-friendly method to synthesize an N-CQD composite. Additionally, they can serve as a universal bacterial membrane-staining dye, with better photobleaching resistance than commercial dyes.

scholarly journals Influence of Graphene Quantum Dots Surface Charge on their Uptake and Clearance in Melanoma Cells

2021 ◽  
Author(s):  
Lakshmi Narashimhan Ramana ◽  
Le N.M. Dinh ◽  
Vipul Agarwal
Keyword(s):  
Quantum Dots ◽  
Surface Charge ◽  
Biomedical Applications ◽  
Graphene Quantum Dots ◽  
Melanoma Cells ◽  
Rapid Clearance

Graphene quantum dots (GQDs) continue to draw interest in biomedical applications. However, their efficacy gets compromised due to their rapid clearance from body. On one side, rapid clearance is desired...

Facile and simultaneous synthesis of graphene quantum dots and reduced graphene oxide for bio-imaging and supercapacitor applications

2016 ◽  
Vol 40 (11) ◽  
pp. 9111-9124 ◽  
Author(s):  
A. Muthurasu ◽  
P. Dhandapani ◽  
V. Ganesh
Keyword(s):  
Quantum Dots ◽  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Graphene Quantum Dots ◽  
Reduced Graphene ◽  
Bio Imaging ◽  
Simultaneous Synthesis ◽  
Supercapacitor Applications

A simple and facile method for the simultaneous preparation of graphene quantum dots (GQDs) having different emission colours, viz., yellow, green and blue, and reduced graphene oxide (RGO) utilized respectively for bio-imaging and supercapacitor applications is demonstrated.

Two-Photon Fluorescence and MR Bio-imaging of Endogenous H2O2 in Tumor Microenvironment by a Dual-Mode Nanoprobe

2021 ◽  
Author(s):  
Hongmei Zhong ◽  
Shengrong Yu ◽  
Bingqian Li ◽  
Kangdi He ◽  
Dian Li ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Tumor Microenvironment ◽  
Mr Imaging ◽  
High Selectivity ◽  
Carbon Quantum Dots ◽  
Dual Mode ◽  
Two Photon ◽  
Bio Imaging ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

Dual-mode bio-imaging nanoprobe TP-CQDs@MnO2, based two-photon carbon quantum dots and MnO2, has been developed for two-photon fluorescence and MR imaging of endogenous H2O2 in tumor microenvironment, which achieved high selectivity,...

scholarly journals Carbon Based Nanodots in Early Diagnosis of Cancer

2021 ◽  
Vol 9 ◽  
Author(s):  
Gurpal Singh ◽  
Harinder Kaur ◽  
Akanksha Sharma ◽  
Joga Singh ◽  
Hema Kumari Alajangi ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Early Stage ◽  
Imaging Techniques ◽  
Graphene Quantum Dots ◽  
Carbon Quantum Dots ◽  
Diagnostic Methods ◽  
Early Diagnosis Of Cancer ◽  
Successful Treatment Outcome ◽  
Wide Range ◽  
Carbon Based

Detection of cancer at an early stage is one of the principal factors associated with successful treatment outcome. However, current diagnostic methods are not capable of making sensitive and robust cancer diagnosis. Nanotechnology based products exhibit unique physical, optical and electrical properties that can be useful in diagnosis. These nanotech-enabled diagnostic representatives have proved to be generally more capable and consistent; as they selectively accumulated in the tumor site due to their miniscule size. This article rotates around the conventional imaging techniques, the use of carbon based nanodots viz Carbon Quantum Dots (CQDs), Graphene Quantum Dots (GQDs), Nanodiamonds, Fullerene, and Carbon Nanotubes that have been synthesized in recent years, along with the discovery of a wide range of biomarkers to identify cancer at early stage. Early detection of cancer using nanoconstructs is anticipated to be a distinct reality in the coming years.

Synthesis and Surface Engineering of Carbon Quantum Dots by Electrical Discharges Generated Inside and in Contact with Liquid

2021 ◽  
Vol MA2021-01 (23) ◽  
pp. 898-898
Author(s):  
Natalie Tarasenka ◽  
Alena Nevar ◽  
Mikhail Nedelko ◽  
Nikolai Tarasenko
Keyword(s):  
Quantum Dots ◽  
Surface Engineering ◽  
Carbon Quantum Dots ◽  
Electrical Discharges

scholarly journals Graphene Quantum Dots as Flourishing Nanomaterials for Bio-Imaging, Therapy Development, and Micro-Supercapacitors

Micromachines ◽  
2020 ◽  
Vol 11 (9) ◽  
pp. 866
Author(s):  
Merve Kortel ◽  
Bhargav D. Mansuriya ◽  
Nicole Vargas Santana ◽  
Zeynep Altintas
Keyword(s):  
Quantum Dots ◽  
Structural Properties ◽  
Edge Effects ◽  
Quantum Confinement ◽  
Review Paper ◽  
Graphene Quantum Dots ◽  
Heteroatom Doping ◽  
Size Dependent ◽  
Bio Imaging ◽  
Therapy Development

Graphene quantum dots (GQDs) are considerably a new member of the carbon family and shine amongst other members, thanks to their superior electrochemical, optical, and structural properties as well as biocompatibility features that enable us to engage them in various bioengineering purposes. Especially, the quantum confinement and edge effects are giving GQDs their tremendous character, while their heteroatom doping attributes enable us to specifically and meritoriously tune their prospective characteristics for innumerable operations. Considering the substantial role offered by GQDs in the area of biomedicine and nanoscience, through this review paper, we primarily focus on their applications in bio-imaging, micro-supercapacitors, as well as in therapy development. The size-dependent aspects, functionalization, and particular utilization of the GQDs are discussed in detail with respect to their distinct nano-bio-technological applications.

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