pH sensitive composite hydrogels based on gelatin and reinforced with cellulose microcrystals: In depth physicochemical and microstructural analyses for controlled release of vitamin B2

2021 ◽  
Vol 27 ◽  
pp. 102334
Author(s):  
Soumaya Boughriba ◽  
Nabil Souissi ◽  
Rim Nasri ◽  
Moncef Nasri ◽  
Suming Li
Keyword(s):  
Controlled Release ◽  
Ph Sensitive ◽  
Vitamin B2 ◽  
Composite Hydrogels

Preparation and characterization of a novel pH-sensitive Salecan-g-poly(acrylic acid) hydrogel for controlled release of doxorubicin

2015 ◽  
Vol 3 (13) ◽  
pp. 2685-2697 ◽  
Author(s):  
Xinyu Hu ◽  
Wei Wei ◽  
Xiaoliang Qi ◽  
Hao Yu ◽  
Liandong Feng ◽  
...  
Keyword(s):  
Controlled Release ◽  
Acrylic Acid ◽  
Ph Sensitive ◽  
Swelling Behaviour ◽  
Poly Acrylic Acid

The pH-sensitive swelling behaviour and DOX release of Salecan-g-PAA hydrogels are discussed.

P(VPBA-DMAEA) as a pH-sensitive nanovalve for mesoporous silica nanoparticles based controlled release

2015 ◽  
Vol 26 (10) ◽  
pp. 1203-1208 ◽  
Author(s):  
Yu-Jie Chang ◽  
Xi-Zhen Liu ◽  
Qing Zhao ◽  
Xiao-Hai Yang ◽  
Ke-Min Wang ◽  
...  
Keyword(s):  
Controlled Release ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Ph Sensitive

scholarly journals ATRP-based synthesis of a pH-sensitive amphiphilic block polymer and its self-assembled micelles with hollow mesoporous silica as DOX carriers for controlled drug release

RSC Advances ◽  
2021 ◽  
Vol 11 (48) ◽  
pp. 29986-29996
Author(s):  
Xiuxiu Qi ◽  
Hongmei Yan ◽  
Yingxue Li
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Self Assembly ◽  
Drug Loading ◽  
Controlled Drug Release ◽  
Ph Sensitive ◽  
Core Shell ◽  
Assembly Process ◽  
Block Polymer ◽  
Hollow Mesoporous Silica

A pH-sensitive core–shell nanoparticle (HMS@C18@PSDMA-b-POEGMA) was developed via a self-assembly process as the carrier of anticancer drug doxorubicin (DOX) for drug loading and controlled release.

scholarly journals Plasma Deposition and UV Light Induced Surface Grafting Polymerization of NIPAAm on Stainless Steel for Enhancing Corrosion Resistance and Its Drug Delivery Property

Polymers ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1009 ◽  
Author(s):  
Ko-Shao Chen ◽  
Shu-Ju Chang ◽  
Chi-Kuang Feng ◽  
Win-Li Lin ◽  
Shu-Chuan Liao
Keyword(s):  
Drug Delivery ◽  
Stainless Steel ◽  
Corrosion Resistance ◽  
Uv Light ◽  
Plasma Deposition ◽  
Ph Sensitive ◽  
Fixed Temperature ◽  
Composite Hydrogels ◽  
Polarization Dynamic ◽  
Silicone Film

When stainless steel is implanted in human bodies, the corrosion resistance and biocompatibility must be considered. In this study, first, a protective organic silicone film was coated on the surface of stainless steel by a plasma deposition technique with a precursor of hexamethyldisilazane (HMDSZ). Then, ultraviolet (UV) light-induced graft polymerization of N-isopropylacrylamide (NIPAAm) and acrylic acid (AAc) in different molar ratios were applied onto the organic silicone film in order to immobilize thermos-/pH-sensitive composite hydrogels on the surface. The thermo-/pH-sensitive composite hydrogels were tested at pH values of 4, 7.4 and 10 of a phosphate buffer saline (PBS) solution at a fixed temperature of 37 °C to observe the swelling ratio and drug delivery properties of caffeine which served as a drug delivery substance. According to the results of Fourier Transformation Infrared (FTIR) spectra and a potential polarization dynamic test, the silicone thin film formed by plasma deposition not only improved the adhesion ability between the substrate and hydrogels but also exhibited a high corrosion resistance. Furthermore, the composite hydrogels have an excellent release ratio of up to 90% of the absorbed amount after 8h at a pH of 10. In addition, the results of potential polarization dynamic tests showed that the corrosion resistance of stainless steel could be improved by the HMDSZ plasma deposition.

Electrospun poly(NVCL-co-AA) fibers as potential thermo-and pH-sensitive agents for controlled release of hydrophobic drugs

2022 ◽  
Vol 276 ◽  
pp. 115531
Author(s):  
Marwa Sta ◽  
Dayane B. Tada ◽  
Simone F. Medeiros ◽  
Amilton M. Santos ◽  
Nicole R. Demarquette
Keyword(s):  
Controlled Release ◽  
Ph Sensitive ◽  
Hydrophobic Drugs
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