Self-regulation of stress-related large-scale brain network balance using real-time fMRI Neurofeedback

It has recently been shown that acute stress affects the allocation of neural resources between large-scale brain networks, and the balance between the executive control network and the salience network in particular. Maladaptation of this dynamic resource reallocation process is thought to play a major role in stress-related psychopathology, suggesting that stress resilience may be determined by the retained ability to adaptively reallocate neural resources between these two networks. Actively training this ability could hence be a potentially promising way to increase resilience in individuals at risk for developing stress-related symptomatology. Using real-time functional Magnetic Resonance Imaging, the current study investigated whether individuals can learn to self-regulate stress-related large-scale network balance. Participants were engaged in a bidirectional and implicit real-time fMRI neurofeedback paradigm in which they were intermittently provided with a visual representation of the difference signal between the average activation of the salience and executive control networks, and tasked with attempting to self-regulate this signal. Our results show that, given feedback about their performance over three training sessions, participants were able to (1) learn strategies to differentially control the balance between SN and ECN activation on demand, as well as (2) successfully transfer this newly learned skill to a situation where they (a) did not receive any feedback anymore, and (b) were exposed to an acute stressor in form of the prospect of a mild electric stimulation. The current study hence constitutes an important first successful demonstration of neurofeedback training based on stress-related large-scale network balance - a novel approach that has the potential to train control over the central response to stressors in real-life and could build the foundation for future clinical interventions that aim at increasing resilience.

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Network dynamics with BrainX3: a large-scale simulation of the human brain network with real-time interaction

Frontiers in Neuroinformatics ◽

10.3389/fninf.2015.00002 ◽

2015 ◽

Vol 9 ◽

Cited By ~ 30

Author(s):

Xerxes D. Arsiwalla ◽

Riccardo Zucca ◽

Alberto Betella ◽

Enrique Martinez ◽

David Dalmazzo ◽

...

Keyword(s):

Human Brain ◽

Real Time ◽

Large Scale ◽

Network Dynamics ◽

Brain Network ◽

Large Scale Simulation ◽

Time Interaction

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Methods for the Quantification of Salivary Cortisol and of a-amylase in Biosensors and Portable Devices

Revista de Chimie ◽

10.37358/rc.17.12.5994 ◽

2018 ◽

Vol 68 (12) ◽

pp. 2857-2859

Author(s):

Cristina Mihaela Ghiciuc ◽

Andreea Silvana Szalontay ◽

Luminita Radulescu ◽

Sebastian Cozma ◽

Catalina Elena Lupusoru ◽

...

Keyword(s):

Real Time ◽

Medical Practice ◽

Salivary Cortisol ◽

Clinical Studies ◽

Large Scale ◽

Psychological Research ◽

Portable Devices ◽

Salivary Amylase ◽

Specificity And Sensitivity

There is an increasing interest in the analysis of salivary biomarkers for medical practice. The objective of this article was to identify the specificity and sensitivity of quantification methods used in biosensors or portable devices for the determination of salivary cortisol and salivary a-amylase. There are no biosensors and portable devices for salivary amylase and cortisol that are used on a large scale in clinical studies. These devices would be useful in assessing more real-time psychological research in the future.

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A Model-Based Real-Time Intrusion Detection System for Large Scale Heterogeneous Networks

10.21236/ada420824 ◽

2003 ◽

Cited By ~ 1

Author(s):

Richard A. Kemmer ◽

Giovanni Vigna

Keyword(s):

Intrusion Detection ◽

Real Time ◽

Heterogeneous Networks ◽

Intrusion Detection System ◽

Large Scale ◽

Detection System ◽

Model Based

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BattleNet: Capturing Advantageous Battlefield in RTS Games (Student Abstract)

Proceedings of the AAAI Conference on Artificial Intelligence ◽

10.1609/aaai.v34i10.7197 ◽

2020 ◽

Vol 34 (10) ◽

pp. 13849-13850

Author(s):

Donghyeon Lee ◽

Man-Je Kim ◽

Chang Wook Ahn

Keyword(s):

Artificial Intelligence ◽

Decision Making ◽

Real Time ◽

Large Scale ◽

Outcome Predictor ◽

Short Term ◽

Rts Game

In a real-time strategy (RTS) game, StarCraft II, players need to know the consequences before making a decision in combat. We propose a combat outcome predictor which utilizes terrain information as well as squad information. For training the model, we generated a StarCraft II combat dataset by simulating diverse and large-scale combat situations. The overall accuracy of our model was 89.7%. Our predictor can be integrated into the artificial intelligence agent for RTS games as a short-term decision-making module.

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A new method to predict anomaly in brain network based on graph deep learning

Reviews in the Neurosciences ◽

10.1515/revneuro-2019-0108 ◽

2020 ◽

Vol 31 (6) ◽

pp. 681-689

Author(s):

Jalal Mirakhorli ◽

Hamidreza Amindavar ◽

Mojgan Mirakhorli

Keyword(s):

Deep Learning ◽

Large Scale ◽

Brain Plasticity ◽

Brain Network ◽

High Order ◽

Brain Diseases ◽

Simultaneous Occurrence ◽

Generative Adversarial Network ◽

The Brain ◽

Brain Connections

AbstractFunctional magnetic resonance imaging a neuroimaging technique which is used in brain disorders and dysfunction studies, has been improved in recent years by mapping the topology of the brain connections, named connectopic mapping. Based on the fact that healthy and unhealthy brain regions and functions differ slightly, studying the complex topology of the functional and structural networks in the human brain is too complicated considering the growth of evaluation measures. One of the applications of irregular graph deep learning is to analyze the human cognitive functions related to the gene expression and related distributed spatial patterns. Since a variety of brain solutions can be dynamically held in the neuronal networks of the brain with different activity patterns and functional connectivity, both node-centric and graph-centric tasks are involved in this application. In this study, we used an individual generative model and high order graph analysis for the region of interest recognition areas of the brain with abnormal connection during performing certain tasks and resting-state or decompose irregular observations. Accordingly, a high order framework of Variational Graph Autoencoder with a Gaussian distributer was proposed in the paper to analyze the functional data in brain imaging studies in which Generative Adversarial Network is employed for optimizing the latent space in the process of learning strong non-rigid graphs among large scale data. Furthermore, the possible modes of correlations were distinguished in abnormal brain connections. Our goal was to find the degree of correlation between the affected regions and their simultaneous occurrence over time. We can take advantage of this to diagnose brain diseases or show the ability of the nervous system to modify brain topology at all angles and brain plasticity according to input stimuli. In this study, we particularly focused on Alzheimer’s disease.

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Impacts of real-time information levels in public transport: A large-scale case study using an adaptive passenger path choice model

Transportation Research Part A Policy and Practice ◽

10.1016/j.tra.2021.03.011 ◽

2021 ◽

Vol 148 ◽

pp. 155-182

Author(s):

Mads Paulsen ◽

Thomas Kjær Rasmussen ◽

Otto Anker Nielsen

Keyword(s):

Real Time ◽

Public Transport ◽

Large Scale ◽

Choice Model ◽

Real Time Information ◽

Time Information

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Modeling Fused Filament Fabrication using Artificial Neural Networks

Production Engineering ◽

10.1007/s11740-021-01020-y ◽

2021 ◽

Author(s):

Paul Oehlmann ◽

Paul Osswald ◽

Juan Camilo Blanco ◽

Martin Friedrich ◽

Dominik Rietzel ◽

...

Keyword(s):

Real Time ◽

Large Scale ◽

Cost Effective ◽

Print Quality ◽

Ann Model ◽

Production Environment ◽

Fused Filament Fabrication ◽

Artificial Neural ◽

Using Data ◽

Artificial Neural Network Ann

AbstractWith industries pushing towards digitalized production, adaption to expectations and increasing requirements for modern applications, has brought additive manufacturing (AM) to the forefront of Industry 4.0. In fact, AM is a main accelerator for digital production with its possibilities in structural design, such as topology optimization, production flexibility, customization, product development, to name a few. Fused Filament Fabrication (FFF) is a widespread and practical tool for rapid prototyping that also demonstrates the importance of AM technologies through its accessibility to the general public by creating cost effective desktop solutions. An increasing integration of systems in an intelligent production environment also enables the generation of large-scale data to be used for process monitoring and process control. Deep learning as a form of artificial intelligence (AI) and more specifically, a method of machine learning (ML) is ideal for handling big data. This study uses a trained artificial neural network (ANN) model as a digital shadow to predict the force within the nozzle of an FFF printer using filament speed and nozzle temperatures as input data. After the ANN model was tested using data from a theoretical model it was implemented to predict the behavior using real-time printer data. For this purpose, an FFF printer was equipped with sensors that collect real time printer data during the printing process. The ANN model reflected the kinematics of melting and flow predicted by models currently available for various speeds of printing. The model allows for a deeper understanding of the influencing process parameters which ultimately results in the determination of the optimum combination of process speed and print quality.

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