Influence of toll-like receptor 4 gene variants and plasma fatty acid profile on systemic inflammation: A population-based cross-sectional study

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Erica Oki ◽  
Antonio A.F. Carioca ◽  
Inar A. Castro ◽  
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Lorraine Brennan ◽  
Breige A. McNulty ◽  
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pp. 659-666 ◽  
Author(s):  
Marina Maintinguer Norde ◽  
Erica Oki ◽  
Antonio Augusto Ferreira Carioca ◽  
Nágila Raquel Teixeira Damasceno ◽  
Regina Mara Fisberg ◽  
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Nutrition ◽  
2016 ◽  
Vol 32 (1) ◽  
pp. 88-94 ◽  
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Erica Oki ◽  
Marina M. Norde ◽  
Antônio A.F. Carioca ◽  
Renata E. Ikeda ◽  
José M.P. Souza ◽  
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PLoS ONE ◽  
2013 ◽  
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pp. e67270 ◽  
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Karina Standahl Olsen ◽  
Christopher Fenton ◽  
Livar Frøyland ◽  
Marit Waaseth ◽  
Ruth H. Paulssen ◽  
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BMJ Open ◽  
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Vol 11 (2) ◽  
pp. e041755
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Srinivas Marmamula ◽  
Satya Brahmanandam Modepalli ◽  
Thirupathi Reddy Kumbham ◽  
Rajesh Challa ◽  
Jill E Keeffe

ObjectivesTo assess the prevalence of disabilities (vision, hearing, mobility, cognitive, self-care and communication) and non-communicable diseases (NCDs) among the elderly population in two districts in Telangana, India.DesignPopulation-based cross-sectional study using a cluster random sampling method to select the study clusters.SettingElderly population in Khammam and Warangal districts were recruited. Detailed interviews were conducted by trained community health workers. Personal and demographic information such as age, gender, level of education and a self-report of NCDs was collected. The Washington Disability Questionnaire was administered to assess the presence of disabilities.Participants1821 participants aged ≥60 years, 54.5% were women, and 73.3% had no education.Primary outcome measurePrevalence of disabilities and NCDs.ResultsOverall, the prevalence of at least disability was 20.3% (95% CI 16.3 to 24.9). The prevalence of self- reported disabilities were: seeing (5.9%; 95% CI 4.4 to 7.8), mobility (12.8%; 95% CI 9.7 to 16.8), hearing (3.6%; 95% CI 2.7 to 4.8), cognition (4.8%; 95% CI 3.5 to 6.7), self-care (3.3%; 95% CI 2.3 to 4.7) and communication (1.8%; 95% CI 1.2 to 2.6). Overall, the prevalence of at least one NCD was 34.2% (95% CI 30.9 to 37.7). Hypertension was the most common systemic condition (25.4%; 95% CI 22.4 to 28.7), followed by diabetes (9.0%; 95% CI 7.3 to 11.0), and body pains (muscle-skeletal) (9.9%; 95% CI 8.1 to 12.2).ConclusionEvery fifth elderly person in the districts of Khammam and Warangal in Telangana had at least one self-reported disability. Besides, a third of the elderly had at least one NCD. There is a definite need to develop comprehensive public health strategies to address disabilities and NCDs in Telangana.


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