scholarly journals Balancing proportions of competing omega-3 and omega-6 highly unsaturated fatty acids (HUFA) in tissue lipids

Author(s):  
Doug Bibus ◽  
Bill Lands
2012 ◽  
Vol 90 (1) ◽  
pp. 55-73 ◽  
Author(s):  
Heinz Rupp ◽  
Thomas P. Rupp ◽  
Peter Alter ◽  
Bernhard Maisch

The causes of reduced levels of omega-3 and omega-6 highly unsaturated fatty acids (“HUFA deficiency”) in heart failure remain unresolved. HUFA profiles were examined in the serum of 331 patients with failing versus nonfailing heart disease. Arachidonic acid was positively correlated (P < 0.001) with eicosapentaenoic acid (EPA) (r = 0.40) and docosahexaenoic acid (DHA) (r = 0.53) and negatively with palmitic (r = 0.42), palmitoleic (r = 0.38), and oleic acid (r = 0.48). Delta-5 desaturase activity was reduced (P < 0.01) in heart failure patients with low ejection fraction, dilatation, increased wall stress, and reduced heart rate variability (SDNN). In these patients, the reduced (P < 0.01) HUFA and increased palmitic (P < 0.01) and oleic acid (P = 0.05) arose from separate influences involving reduced cardiac contractility (arachidonic acid and palmitic acid predicted by ejection fraction) and chamber dilatation (DHA and oleic acid predicted by end-diastolic diameter). A low DHA (0.2%–0.9% versus 1.4%–3.1%) was associated (P < 0.025) with atrial dilatation (44 ± 8 mm versus 40 ± 8 mm). Equidirectional but less pronounced effects on HUFA were induced by sympathetic activation and (or) insulin resistance (fat and sugar fed to deoxycorticosterone acetate (DOCA)-salt rats) but not by compensated cardiac overload alone (DOCA-salt or aortic constriction), or reduced fatty acid oxidation (CPT-1 inhibition). Based on administration of omega-3 HUFA (OMACOR), dilatation is identified as a target for 1–2 g omega-3 HUFA·day–1. Interventions for reduced arachidonic acid remain to be explored.


2014 ◽  
Vol 4 (1) ◽  
pp. 31-39
Author(s):  
Siwitri Kadarsih

The objective was to get beef that contain unsaturated fatty acids (especially omega 3 and 6), so as to improve intelligence, physical health for those who consume. The study design using CRD with 3 treatments, each treatment used 4 Bali cattle aged approximately 1.5 years. Observations were made 8 weeks. Pasta mixed with ginger provided konsentrat. P1 (control); P2 (6% saponification lemuru fish oil, olive oil 1%; rice bran: 37.30%; corn: 62.70%; KLK: 7%, ginger paste: 100 g); P3 (lemuru fish oil saponification 8%, 2% olive oil; rice bran; 37.30; corn: 62.70%; KLK: 7%, ginger paste: 200 g). Konsentrat given in the morning as much as 1% of the weight of the cattle based on dry matter, while the grass given a minimum of 10% of the weight of livestock observation variables include: fatty acid composition of meat. Data the analyzies qualitative. The results of the study showed that the composition of saturated fatty acids in meat decreased and an increase in unsaturated fatty acids, namely linoleic acid (omega 6) and linolenic acid (omega 3), and deikosapenta deikosaheksa acid.Keywords : 


2019 ◽  
Vol 20 (2) ◽  
pp. 120-131
Author(s):  
Settings Anang Suhardianto ◽  
Ariyanti Hartari

This study aims to determine the effect of stocking density on the nutrient content of catfish that is maintained with biofloc technology. Nutrients observed: 1) water content, 2) protein, 3) carbohydrates, 4) total fat, 5) saturated fatty acids / SFA, 6) monounsaturated fatty acids/ MUFA, 7) plural unsaturated fatty acids / PUFA , 8) omega-3, 9) omega-6, and 10) omega 9. Statistical tests on the 10 variables showed that stocking density did not have a significant effect on the 10 variables at a 5% confidence interval. Stocking density of treatment is 1000 heads/pond (T1), 2000 heads/pond (T2), 3000 heads/pond (T3), with a pond size of 2.0 m x height 1.0 m. Research results: 1. The average water content is 69.40–71.47% and the highest T3. 2. The protein content is 14.70-15.90%, the highest T2. 3. Carbohydrate content of 5.16-5.50%, the highest T2. 4. The average total fat content of 6.73-7.78%, the highest T1. 5. SFA content is around 43%, PUFA around 23%, and MUFA around 32%. 6. The highest omega-3 content is T3, then T1, and T2. Omega-6 and 9 sequence contents are T1, T2, and T3. It was concluded, the treatment of biofloc catfish stocking densities at a 5% confidence interval did not have a significant effect on the specified nutrient content. Penelitian ini bertujuan untuk menentukan pengaruh padat tebar terhadap kandungan zat gizi ikan lele yang dipelihara dengan teknologi bioflok. Zat gizi yang diamati: 1) kandungan air, 2) protein, 3) karbohidrat, 4) lemak total, 5) asam lemak jenuh/SFA, 6) asam lemak tak jenuh tunggal/MUFA, 7) asam lemak tak jenuh jamak/PUFA, 8) omega-3, 9) omega 6, dan 10) omega 9. Uji statistik terhadap ke-10 variabel menunjukkan padat tebar tidak memberikan pengaruh nyata terhadap ke-10 variabel pada selang kepercayaan 5%.  Padat tebar perlakuan adalah 1000 ekor/kolam (T1),  2000 ekor/kolam (T2), 3000 ekor/kolam (T3), dengan ukuran kolam diameter 2,0 m x tinggi 1,0 m. Hasil penelitian: 1. Rata-rata kandungan air 69,40–71,47% dan T3 tertinggi. 2. Kandungan protein 14,70–15,90%, T2 tertinggi. 3. Kandungan karbohidrat 5,16–5,50%, T2 tertinggi. 4. Rata-rata kandungan lemak total 6,73–7,98%, T1 tertinggi. 5. Kandungan SFA sekitar 43%, PUFA sekitar 23%, dan MUFA sekitar 32%. 6. Kandungan omega-3 tertinggi T3, kemudian T1, dan T2. Omega-6 dan 9 urutan kandungannya T1, T2, dan T3.  Disimpulkan, perlakuan padat tebar lele bioflok pada selang kepercayaan 5% tidak memberikan pengaruh yang nyata terhadap kandungan zat gizi yang ditentukan.


2017 ◽  
Vol 221 (3) ◽  
pp. jeb165373 ◽  
Author(s):  
Cornelia W. Twining ◽  
Peter Lawrence ◽  
David W. Winkler ◽  
Alexander S. Flecker ◽  
J. Thomas Brenna

2017 ◽  
Vol 68 (3) ◽  
pp. 507-509 ◽  
Author(s):  
Dana Copolovici ◽  
Simona Bungau ◽  
Rica Boscencu ◽  
Delia Mirela Tit ◽  
Lucian Copolovici

The fatty acids composition and antioxidant activity have been determinate for cold press walnut oil. It has been found that the total saturated fatty acids have been 8.8 % while poly unsaturated fatty acids have been 72.84 %. The ratio between omega-6 and omega-3 has been determined as 5.06 which could help in human healthy diet. On the same side, the antioxidant activity of the oil is very high at a level of 3.65 mmol L-1 and a ratio between lipophilic and hydrophilic fractions of 9.45.


2013 ◽  
Vol 48 (5) ◽  
pp. 553-558 ◽  
Author(s):  
Luis Fernando Glasenapp de Menezes ◽  
Luciane Rumpel Segabinazzi ◽  
João Restle ◽  
Leandro da Silva Freitas ◽  
Ivan Luiz Brondani ◽  
...  

The objective of this work was to evaluate the meat lipid profile from Devon beef steers finished in pearl millet (Pennisetum americanum) pasture and fed at different rates of concentrate supplementary diet. Twelve steers weighing 270 kg, at 12‑month‑average initial age, were randomly distributed into three treatments: pearl millet pasture; and pearl millet pasture plus a concentrate equivalent at 0.5 or 1.0% of body weight, with two replicates. Total contents of saturated and unsaturated fatty acids, the polyunsaturated:saturated ratio and other relevant fatty acids as the vaccenic acid, conjugated linoleic acid, omega‑3, and omega‑6 were not affected by the consumption of a concentrate supplement at 0.5 or 1.0% live weight. However, the 0.5% supplementation level reduced the concentration of dihomo‑γ‑linolenic fatty acid (C20: 3 n‑6), while the 1.0% supplementation level elevated the content of docosahexaenoic (DHA) (C22: 6 n‑3) fatty acid, and the omega‑6:omega‑3 ratio in meat. Consumption of up to 1.0% energy supplementation increases the omega‑6:omega‑3 ratio in meat from Devon steers grazing on pearl millet pasture.


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