PP104. Pregnancy-induced hypertension is a strong risk factor for hypertension just 5 years after delivery: A double cohort study at the National Center for Child Health and Development and Showa University Hospital, Tokyo

Abstract Objective The objective of this study was to assess the effect of pregnancy-induced hypertension on adverse maternal outcomes in Tigray Regional State, Ethiopia. A prospective cohort study was conducted on a total sample of 782 pregnant women attending antenatal care in hospitals of Tigray regional state, Ethiopia. Data were collected using interviewer-administered questionnaire and review of their medical records from February 1, 2018, to February 30, 2019. Data analysis was performed using Stata version 14.0.Results The overall adverse maternal outcome was 67.7% among women with pregnancy-induced hypertension and 25.1% among normotensive women. Specifically women with pregnancy-induced hypertension were at higher risk of developing Antepartum hemorrhage (Adjusted RR=1.4(1.1,2.5)), postpartum hemorrhage (RR=2.6(1.3,4.9)), induction of labor (RR=5.9(4.0,8.7)) and delivering by cesarean section (RR=2.1(1.6,2.8)) compared to normotensive women.

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Diabetes Mellitus as a Risk Factor for Drug Resistance Tuberculosis: A Retrospective Cohort Study at King Abdul Aziz University, Jeddah

Journal of Advances in Medicine and Medical Research ◽

10.9734/jammr/2021/v33i2031115 ◽

2021 ◽

pp. 136-145

Author(s):

Sumyia Mehrin M. D. Abulkalam ◽

Mai Kadi ◽

Mahmoud A. Gaddoury ◽

Wallaa Khalid Albishi

Keyword(s):

Diabetes Mellitus ◽

Drug Resistance ◽

Risk Factor ◽

Cohort Study ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

University Hospital ◽

P Value ◽

Baseline Characteristic ◽

Drug Resistant

Background: The association between tuberculosis (TB) and diabetes mellitus (DM) is re-emerging with the epidemic of type II diabetes. Both TB and DM were of the top 10 causes of death.[1] This study explores diabetes mellitus as a risk factor for developing the different antitubercular drug-resistant (DR) patterns among TB patients. Methods: A retrospective cohort study has been conducted on all TB cases reported to the King Abdul Aziz University Hospital, Jeddah, between January 2012 to January 2021. All culture-confirmed and PCR-positive TB cases were included in this study. Categorical baseline characteristic of TB patient has been compared with DM status by using Fisher's exact and Pearson chi-square test. The univariable and multivariable logistic regression model was used to estimate the association between DM and different drug resistance patterns. Results: Of the total 695 diagnosed TB patients, 92 (13.24%) are resistant to 1st line anti TB drugs. Among 92 DR-TB patients, 36 (39.13%) are diabetic. The percentage of different patterns of DR-TB with DM, in the case of mono DR (12.09%), poly DR (4.19%) MDR (0.547%). As a risk factor, DM has a significant association with DR-TB, mono drug-resistant, and pyrazinamide-resistant TB (P-value <0.05). The MDR and PDR separately do not show any significant association with DM, but for further analysis, it shows a significant association with DM when we combined. Conclusion: Our study identified diabetes mellitus as a risk factor for developing DR-TB. Better management of DM and TB infection caring programs among DM patients might improve TB control and prevent DR-TB development in KSA.

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Intra-Abdominal Hypertension is a Risk Factor for Increased VAP Incidence: A Prospective Cohort Study in the ICU of a Tertiary Hospital

Journal of Intensive Care Medicine ◽

10.1177/0885066618779369 ◽

2018 ◽

Vol 35 (7) ◽

pp. 700-707 ◽

Cited By ~ 1

Author(s):

Eleni Papakrivou ◽

Demosthenes Makris ◽

Efstratios Manoulakas ◽

Marios Karvouniaris ◽

Epaminondas Zakynthinos

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Cohort Study ◽

Cox Regression ◽

Tertiary Hospital ◽

University Hospital ◽

Chronic Obstructive ◽

Obstructive Pulmonary Disease ◽

Cox Regression Analysis ◽

Abdominal Hypertension

Background: Ventilator-associated pneumonia (VAP) might be increased in cases with intra-abdominal hypertension (IAH). However, despite animal experimentation and physiological studies on humans in favor of this hypothesis, there is no definitive clinical data that IAH is associated with VAP. We therefore aimed to study whether IAH is a risk factor for increased incidence of VAP in critical care patients. This 1-center prospective observational cohort study was conducted in the intensive care unit of the University Hospital of Larissa, Greece, during 2013 to 2015. Consecutive patients were recruited if they presented risk factors for IAH at admission and were evaluated systematically for IAH and VAP for a 28-day period. Results: Forty-five (36.6%) of 123 patients presented IAH and 45 (36.6%) presented VAP; 24 patients presented VAP following IAH. Cox regression analysis showed that VAP was independently associated with IAH (1.06 [1.01-1.11]; P = .053), while there was an indication for an independent association between VAP and abdominal surgery (1.62 [0.87-3.03]; P = .11] and chronic obstructive pulmonary disease (1.79 [0.96-3.37]; P = .06). Conclusions: Intra-abdominal hypertension is an independent risk factor for increased VAP incidence in critically ill patients who present risk factors for IAH at admission to the ICU.

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Maternal toenail manganese and pregnancy-induced hypertension in the New Hampshire Birth Cohort Study

Environmental Epidemiology ◽

10.1097/01.ee9.0000607584.58816.e8 ◽

2019 ◽

Vol 3 ◽

pp. 164

Author(s):

Howe C ◽

Baker E ◽

Chen Y ◽

Karagas M ◽

Farzan S

Keyword(s):

Cohort Study ◽

Birth Cohort ◽

New Hampshire ◽

Birth Cohort Study ◽

Pregnancy Induced Hypertension ◽

Induced Hypertension

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PREGNANCY INDUCED HYPERTENSION;

The Professional Medical Journal ◽

10.29309/tpmj/2014.21.03.2125 ◽

2014 ◽

Vol 21 (03) ◽

Author(s):

Asghar Khan ◽

Amin Fahim ◽

Aneela Qureshi ◽

Ghulam Shah Nizamani ◽

Mohammad Ahmed Azmi

Keyword(s):

University Hospital ◽

Control Group ◽

P Value ◽

Pregnancy Induced Hypertension ◽

Severity Of Disease ◽

Induced Hypertension ◽

Mild Preeclampsia ◽

Group 3 ◽

Group 2 ◽

Group 1

Objective: To assess the early detection of thrombocytopenia in womenpresenting with varying degree of pregnancy induced hypertension (PIH). Study Design: A casecontrol study. Place of Study: Hematology laboratory Isra University Hospital Hyderabad.Duration of Study: From July 2009 to December 2010. Materials and Methods: Total 130pregnant women were included in this study. The subjects were divided into three groups asGroup 1 with pre-eclampsia, Group 2 with eclampsia and Group 3 with normotensive pregnantwomen as control group. The Group 1 was further divided into two sub groups such as Subgroup1a with mild preeclampsia and Sub-group 2b with severe pre-eclampsia. Results:Anticoagulated whole blood samples (5cc) from all subjects were analyzed for the detection ofthrombocytopenia for the possible involvement of pregnancy induced hypertension. It was notedthat out of total subjects, 33(25.39%) had mild pre-eclampsia, 17(13.07%) had severe preeclampsia,15(11.54%) had eclampsia and 65 (50.0%) were normotensive pregnant women.Based on the comparative findings, the results showed significant differences between group 3and group 1a (p-value 0.001), group 3 and group 1b (p-value 0.001), group 2 and group 3 alsoshowed same results (p-value 0.001) but the subjects of group 1a and 1b when compared,showed non-significant findings (p value 0.955). Conclusion: The results suggested that earlydetection of platelet count provide significant role for the assessment of severity of disease inwomen with pregnancy induced hypertension when compared with normotensive pregnantwomen.

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Risk factors for necrotizing enterocolitis in neonates:a prospective study

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20192762 ◽

2019 ◽

Vol 6 (4) ◽

pp. 1598

Author(s):

Manas Ranjan Sahoo ◽

Pydi Nagasree ◽

Lanka Swetha ◽

Arigela Vasundhara

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Prospective Study ◽

Necrotizing Enterocolitis ◽

Neonatal Intensive Care ◽

Ductus Arteriosus ◽

Pregnancy Induced Hypertension ◽

Mortality And Morbidity ◽

Maternal Risk ◽

Induced Hypertension

Background: Necrotizing enterocolitis (NEC) is mostly limited to preterm babies due to immaturity of gut. NEC is one of important cause of neonatal mortality and morbidity in the neonatal intensive care units all over the world.Aim of study is to find the antenatal and post-natal risk factors associated with necrotizing enterocolitis in neonates admitted to NICU.Methods: A prospective study was conducted on 45 neonates with necrotizing enterocolitis fulfilling the predetermined inclusion criteria. A detailed antenatal history including all maternal risk factors, birth history including the need for resuscitation and type of resuscitation was recorded. The gestational assessment was done by the New Ballard Score.Results: Pregnancy induced hypertension accounts as a risk factor to most of the cases of NEC 18 (40%), followed by setting for sepsis 12 (26.6%), least being gestational diabetes mellitus 1 (2.2%).Conclusions: Prematurity is found to be the most common risk factor followed by patent ductus arteriosus and sepsis. Most common antenatal risk factor was PIH (Pregnancy induced hypertension).

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