scholarly journals Risk factors for necrotizing enterocolitis in neonates:a prospective study

2019 ◽  
Vol 6 (4) ◽  
pp. 1598
Author(s):  
Manas Ranjan Sahoo ◽  
Pydi Nagasree ◽  
Lanka Swetha ◽  
Arigela Vasundhara
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Prospective Study ◽  
Necrotizing Enterocolitis ◽  
Neonatal Intensive Care ◽  
Ductus Arteriosus ◽  
Pregnancy Induced Hypertension ◽  
Mortality And Morbidity ◽  
Maternal Risk ◽  
Induced Hypertension

Background: Necrotizing enterocolitis (NEC) is mostly limited to preterm babies due to immaturity of gut. NEC is one of important cause of neonatal mortality and morbidity in the neonatal intensive care units all over the world.Aim of study is to find the antenatal and post-natal risk factors associated with necrotizing enterocolitis in neonates admitted to NICU.Methods: A prospective study was conducted on 45 neonates with necrotizing enterocolitis fulfilling the predetermined inclusion criteria. A detailed antenatal history including all maternal risk factors, birth history including the need for resuscitation and type of resuscitation was recorded. The gestational assessment was done by the New Ballard Score.Results: Pregnancy induced hypertension accounts as a risk factor to most of the cases of NEC 18 (40%), followed by setting for sepsis 12 (26.6%), least being gestational diabetes mellitus 1 (2.2%).Conclusions: Prematurity is found to be the most common risk factor followed by patent ductus arteriosus and sepsis. Most common antenatal risk factor was PIH (Pregnancy induced hypertension).

scholarly journals Morbidity and mortality profile of preterm neonates admitted in neonatal intensive care unit of a tertiary care centre in Western Uttar Pradesh, India

2019 ◽  
Vol 6 (5) ◽  
pp. 1859
Author(s):  
Najia Hassan ◽  
Sujaya Mukhopadhyay ◽  
Sneha Mohan
Keyword(s):  
Risk Factors ◽  
Neonatal Intensive Care ◽  
Tertiary Care ◽  
Preterm Neonates ◽  
Pregnancy Induced Hypertension ◽  
Care Centre ◽  
Maternal Risk Factors ◽  
Tertiary Care Centre ◽  
Maternal Risk ◽  
Induced Hypertension

Background: Preterm birth is a major cause of mortality and morbidity for newborns. Complications of prematurity are becoming more common as more survivors are spending time in Neonatal intensive care unit.Methods: A retrospective hospital based clinical observational study was conducted in NICU in Sharda hospital, a tertiary care centre in Greater Noida. Data regarding neonates′ age, sex, clinical presentation, maternal risk factors, complications and outcome were recorded.Results: A total of 133 preterm neonates were enrolled in the study. Maternal risk factors like Pregnancy induced hypertension (PIH) was seen in 19.5% cases, Urinary tract infection in 15% and Antepartum haemorrhage in 14.2% cases. Among the complications of prematurity, RDS was noted in 38.3% cases, Hyperbilirubinemia in 16.5% and feed intolerance in 15% cases. Sepsis was present in 3% of the preterm. Mortality rate was 7.5%. Most common cause of death was RDS.Conclusions: Pregnancy induced hypertension and Antepartum haemorrhage were important maternal risk factors for prematurity. Respiratory distress syndrome and perinatal asphyxia were the important causes of mortality in the present study.

scholarly journals Maternal Risk Factors and Morbidity Pattern of Very Low Birth Weight Infants: A NICU Based Study at Eastern Nepal

2009 ◽  
Vol 29 (2) ◽  
pp. 59-66 ◽  
Author(s):  
Prakash Poudel ◽  
Sunil Budhathoki ◽  
Manoj Kumar Shrivastava
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Ductus Arteriosus ◽  
Pregnancy Induced Hypertension ◽  
Maternal Risk Factors ◽  
Maternal Risk ◽  
Factors Associated ◽  
Induced Hypertension

Background: Preterm deliveries of babies weighing less than 1500 grams (VLBW, very low birth weight) are of major concern because of maximum perinatal morbidity and mortality found in this group. VLBW babies overload the neonatal intensive care unit (NICU) and their mortality contributes significantly to neonatal and infant mortality. Objectives: To study the common maternal risk factors associated with VLBW births. To study the morbidity and mortality patterns of VLBW babies. Methods: This was a hospital based retrospective study done in NICU of BP Koirala Institute of Health Sciences. Data were collected from medical records of VLBW babies admitted in NICU over a period of three years (13 April 2005 to 12 April 2008). Data were analyzed with SPSS 10.0 software. Results: Data of 140 VLBW babies were analyzed. Mean birth weight was 1188.9 (±212.78), 10.7% were home deliveries, 24.3% were twins, 31.4% required active resuscitation at birth and 46.4% were exposed to antenatal steroid. Common maternal risk factors associated with premature deliveries were inadequate antenatal check up (ANC) visits (95.7%), twin pregnancy (24.3%), antepartum hemorrhage (APH, 28.6%), premature rupture of membrane (23.6%), pregnancy induced hypertension (12.9%), bad obstetric history (12.9%) and maternal age less than 20 years (8.6%). Common morbidities among VLBW babies were clinical sepsis (77.1%), non physiological hyperbilirubinemia (73.6%), apnea (48.6%), shock (42.9%), hypoglycemia(39.3%), anemia (29.3%), hyaline membrane disease (HMD, 21.4%), patent ductus arteriosus (15.0%), severe hypothermia (12.1%), culture proven sepsis (15.7%), retinopathy of prematurity (5.7%), and bronchopulmonary dysplasia (3.6%). Overall survival was 54.3% and major causes of death were HMD (51.0%) and sepsis (34.7%). Median durations of hospital stay were 17.5 days for survivors and five days for expired cases.Conclusion: Increasing the coverage of ANC visits, early diagnosis and treatment of APH and pregnancy induced hypertension, discouraging the childbirth at too young age, early diagnosis and treatment of acute infections and chronic medical diseases in mothers are important measures to decrease the burden of VLBW births. Common morbidities in VLBW babies are sepsis, HMD, apnea, hyperbilirubinemia, patent ductus arteriosus, shock, anemia, hypoglycemia, hypothermia and hypocalcemia. Common causes death of VLBW babies are HMD and sepsis. Overall survival of VLBW babies in our settings is less. More numbers of well equipped NICUs and services like surfactant therapy are needed to improve survival of VLBW infants in our set up. Key words: Maternal risk factors, Morbidity, Mortality, Very low birth weight.   doi: 10.3126/jnps.v29i2.2040 J. Nepal Paediatr. Soc. Vol 29, No. 2, pp.59-66

The Chasm in Neonatal Outcomes in Relation to Time of Birth in Lebanon

2007 ◽  
Vol 26 (2) ◽  
pp. 97-102 ◽  
Author(s):  
Lina Kurdahi Badr ◽  
Bahia Abdallah ◽  
Sossi Balian ◽  
Hala Tamim ◽  
Mirvat Hawari
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Intensive Care ◽  
Neonatal Intensive Care ◽  
Night Shift ◽  
Neonatal Intensive Care Units ◽  
Maternal Risk Factors ◽  
Mortality And Morbidity ◽  
Maternal Risk ◽  
The Relationship

Purpose:The purpose of this study was to investigate the relationship between the time of birth and the mortality and morbidity of infants admitted to neonatal intensive care units.Design:This prospective, cohort study examined the records of women and infants admitted to the NICUs of four hospitals in Beirut, Lebanon, between July 1, 2002, and June 30, 2003. The hospitals selected were university affiliated and had a large number of deliveries (5,152 total for the year 2002–2003).Main Outcome Variables:Neonatal mortality and morbidity for infants admitted to the NICU were evaluated in relation to time of birth.Results:For the whole sample, mortality was higher for infants born during the night shift than for those born during the day shift. Mortality, morbidity, and brain asphyxia rates were also higher for infants born during the night shift and admitted to the NICU. Maternal risk factors and delivery complications were not consistently higher on the night shift.

scholarly journals THREE YEARS PROSPECTIVE STUDY OF NECROTIZING ENTEROCOLITIS

2003 ◽  
Vol 42 (149) ◽  
pp. 312-4
Author(s):  
Neeraj Jain ◽  
V Mangal
Keyword(s):  
Intensive Care Unit ◽  
Risk Factor ◽  
Necrotizing Enterocolitis ◽  
Neonatal Intensive Care ◽  
Intestinal Wall ◽  
Common Risk Factor ◽  
Newborn Period ◽  
Mortality And Morbidity ◽  
The Common ◽  
High Index Of Suspicion

Necrotizing Enterocolitis (NEC) is a major cause of mortality and morbidity in the newborn period. Toknow the incidence of NEC at our Neonatal Intensive Care Unit (NICU). Over a 3 year period (Prospectivestudy) ,510 cases were studied for NEC. Incidence was 5.3%, mortality due to NEC was 22%, Asphyxia,Prematurity and enteral feeding were the common risk factor. Abdominal distention, blood in stool and airin intestinal wall were the main clinical features. Prevention and high index of suspicion are important tolimit the morbidity and mortality.Key Words: Necrotizing enterocolitis, Low birth weight.

scholarly journals Necrotizing enterocolitis in term neonates: Possible risk factors

2020 ◽  
Vol 9 ◽  
pp. 22
Author(s):  
Ayman Elhosny ◽  
Corné De Vos ◽  
Behrouz Banieghbal
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Necrotizing Enterocolitis ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Term Neonates ◽  
Maternal Risk ◽  
Premature Neonates ◽  
Study Results ◽  
Neonatal Risk Factors

Background: Necrotizing enterocolitis (NEC) is a common surgical disease in premature neonates, however, it may occasionally occur in term neonates. The etiology of NEC in prematurity is multifactorial but is still not well understood in term neonates. In this study, the maternal and neonatal risk factors, along with underlying pathology that may precipitate NEC in term neonates are investigated.  Methods: A retrospective study investigating the maternal and neonatal risk factors for NEC in term neonates (G.A ≥37 weeks) was performed over an 8-years period (January 2009 to March 2017). We used the second group of healthy term neonates over the same period as a control group. The data were collected from medical records. Term babies with the primary diagnosis of NEC were included in the review. Premature neonates (G.A <37 weeks) and NEC secondary to intestinal obstruction (e.g. Hirschsprung’s disease) were excluded from the study. Results: Of 194 babies with NEC, 14 were term neonates. Maternal risk factors: maternal age, Rhesus status, nicotine use, medication use, chronic and gestational illness were not found to be significant, however, maternal methamphetamine (MA) abuse was found to be a significant risk factor. Neonatal risk factors: genetic disorder, mode of delivery, type of milk, and invasive procedure were not found to be significant, but the presence of congenital heart disease (CHD) was a significant risk factor. Three neonates with CHD (3/4) in the group of term neonates with NEC also had maternal MA use. Conclusion: NEC in term neonates is rarely encountered. CHD is well known to precipitate the disease in premature or full-term neonates, as also noted in this cohort. MA usage was also noted as a possible underlying cause.

scholarly journals Low birth weight at term and maternal contributing factors in community based hospital Korangi, Karachi.

2020 ◽  
Vol 27 (02) ◽  
pp. 324-329
Author(s):  
Saba Pario ◽  
Haniyah Qamar ◽  
Rozina Mustafa
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Risk Factor ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Diabetes ◽  
Pregnancy Induced Hypertension ◽  
Fetal Gender ◽  
Induced Hypertension ◽  
History Of

Low birth weight is a key determinant of infant survival, health and development. Low birth weight infants are at a greater risk of morbidity and mortality than an infant of normal birth weight and create a substantial strain on the healthcare system. Objectives: To determine the frequency of low birth weight at term and maternal contributing risk factors in women attending antenatal clinic at Creek General Hospital Korangi, Karachi. Study Design: Descriptive cross sectional study. Setting: Department of Obstetrics and Gynecology of Creek General Hospital, United Medical and Dental College Karachi. Period: From May 2017 to April 2018. Material & Methods: Those women who gave birth to babies with less than 2500gm at term, were included in the study to ascertain the frequency and risk factors of low birth weight including age, parity, booking status for antenatal care, pre-pregnancy BMI, history of tobacco intake, medical disorders arising in pregnancy like anemia, pregnancy induced hypertension and gestational diabetes mellitus, birth weight and fetal gender. The data was analyzed on SPSS software. Results: The prevalence of term low birth weight was 22%. Percentage of low birth weight babies among teenage mothers was 72.8%, among the studied mothers 67.4% were primipara, 91.5% had standard antenatal care, Pre-pregnancy BMI was found to be normal in 93% of mothers, 9 mothers (7%) had history of tobacco/ betel nut chewing habit. In this study, iron deficiency anemia was found to be most significant factor leading to LBW babies (62 %). 12% and 8% of mothers were diagnosed with Pregnancy induced Hypertension and Gestational Diabetes mellitus respectively. Regarding fetal gender, 68 were females (52.7%) and 61 (47.3%) were males. Conclusion: Low Birth Weight is an important contributing risk factor for perinatal mortality and morbidity in Pakistan. Anemia was found to be most significant risk factor leading to Low birth weight in our study.

scholarly journals Work-Related Maternal Risk Factors and the Risk of Pregnancy Induced Hypertension and Preeclampsia during Pregnancy. The Generation R Study

PLoS ONE ◽  
2012 ◽  
Vol 7 (6) ◽  
pp. e39263 ◽  
Author(s):  
Jaap Jan Nugteren ◽  
Claudia A. Snijder ◽  
Albert Hofman ◽  
Vincent W. V. Jaddoe ◽  
Eric A. P. Steegers ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pregnancy Induced Hypertension ◽  
Maternal Risk Factors ◽  
Maternal Risk ◽  
Work Related ◽  
Induced Hypertension

scholarly journals Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register Study

2021 ◽  
Vol 18 (11) ◽  
pp. 5865
Author(s):  
Salma Younes ◽  
Muthanna Samara ◽  
Rana Al-Jurf ◽  
Gheyath Nasrallah ◽  
Sawsan Al-Obaidly ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hospital Mortality ◽  
Gestational Age ◽  
Neonatal Intensive Care ◽  
Population Based ◽  
Incidence Rates ◽  
Large For Gestational Age ◽  
Mortality And Morbidity ◽  
Early Term ◽  
Incidence Risk

Preterm birth (PTB) and early term birth (ETB) are associated with high risks of perinatal mortality and morbidity. While extreme to very PTBs have been extensively studied, studies on infants born at later stages of pregnancy, particularly late PTBs and ETBs, are lacking. In this study, we aimed to assess the incidence, risk factors, and feto-maternal outcomes of PTB and ETB births in Qatar. We examined 15,865 singleton live births using 12-month retrospective registry data from the PEARL-Peristat Study. PTB and ETB incidence rates were 8.8% and 33.7%, respectively. PTB and ETB in-hospital mortality rates were 16.9% and 0.2%, respectively. Advanced maternal age, pre-gestational diabetes mellitus (PGDM), assisted pregnancies, and preterm history independently predicted both PTB and ETB, whereas chromosomal and congenital abnormalities were found to be independent predictors of PTB but not ETB. All groups of PTB and ETB were significantly associated with low birth weight (LBW), large for gestational age (LGA) births, caesarean delivery, and neonatal intensive care unit (NICU)/or death of neonate in labor room (LR)/operation theatre (OT). On the other hand, all or some groups of PTB were significantly associated with small for gestational age (SGA) births, Apgar <7 at 1 and 5 minutes and in-hospital mortality. The findings of this study may serve as a basis for taking better clinical decisions with accurate assessment of risk factors, complications, and predictions of PTB and ETB.

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