The plasma antioxidant vitamin status of the INTAPP cohort examined: the unsuspected importance of β-carotene and γ-tocopherol in preeclampsia

Author(s):  
Jean-François Bilodeau ◽  
Amélie Gagné ◽  
Karine Greffard ◽  
François Audibert ◽  
William D Fraser ◽  
...  
2017 ◽  
Vol 36 (1) ◽  
pp. 209-217 ◽  
Author(s):  
Marcela Guerendiain ◽  
Jordi Mayneris-Perxachs ◽  
Rosa Montes ◽  
Gemma López-Belmonte ◽  
Miguel Martín-Matillas ◽  
...  

2009 ◽  
Vol 107 (1) ◽  
pp. 54-62 ◽  
Author(s):  
S. R. Zwart ◽  
G. E. Crawford ◽  
P. L. Gillman ◽  
G. Kala ◽  
A. S. Rodgers ◽  
...  

Spaceflight and bed rest models of microgravity have profound effects on physiological systems, including the cardiovascular, musculoskeletal, and immune systems. These effects can be exacerbated by suboptimal nutrient status, and therefore it is critical to monitor nutritional status when evaluating countermeasures to mitigate negative effects of spaceflight. As part of a larger study to investigate the usefulness of artificial gravity as a countermeasure for musculoskeletal and cardiovascular deficits during bed rest, we tested the hypothesis that artificial gravity would have an effect on some aspects of nutritional status. Dietary intake was recorded daily before, during, and after 21 days of bed rest with artificial gravity ( n = 8) or bed rest alone ( n = 7). We examined body composition, hematology, general blood chemistry, markers of oxidative damage, and blood levels of selected vitamins and minerals before, during, and after the bed rest period. Several indicators of vitamin status changed in response to diet changes: serum α- and γ-tocopherol and urinary 4-pyridoxic acid decreased ( P < 0.001) and plasma β-carotene increased ( P < 0.001) in both groups during bed rest compared with before bed rest. A decrease in hematocrit ( P < 0.001) after bed rest was accompanied by a decrease in transferrin (P < 0.001), but transferrin receptors were not changed. These data provide evidence that artificial gravity itself does not negatively affect nutritional status during bed rest. Likewise, artificial gravity has no protective effect on nutritional status during bed rest.


2009 ◽  
Vol 12 (12) ◽  
pp. 2438-2447 ◽  
Author(s):  
Allison M Hodge ◽  
Julie A Simpson ◽  
Masha Fridman ◽  
Kevin Rowley ◽  
Dallas R English ◽  
...  

AbstractObjectiveTo evaluate FFQ estimates of dietary intake of individual antioxidants, fruit and vegetables in comparison to plasma concentrations of each antioxidant, and to determine which individual foods are associated with plasma antioxidant concentrations.DesignDietary (α-carotene, β-carotene, β-cryptoxanthin, lutein/zeaxanthin, lycopene, retinol, and vitamin E) intakes over 12 months were estimated from a 121-item FFQ. Correlation coefficients, corrected for within-person variability in diet and plasma antioxidants, were used to examine associations between antioxidant concentrations in diet and plasma.SettingMelbourne Collaborative Cohort Study (MCCS).SubjectsMen and women (n3110) who were randomly selected from the MCCS. Participants were aged 36–72 years and were born in Australia, Greece, Italy or the UK.ResultsCorrelation coefficients for the carotenoids ranged from 0·28 for lycopene to 0·46 for β-cryptoxanthin. There was no association between dietary and plasma retinol or dietary vitamin E with plasma α- and γ-tocopherol. Individual plasma carotenoid concentrations were associated with intakes of fruit and vegetables.ConclusionsOur data suggest that the FFQ provides useful information on intakes of each of the carotenoids: α-carotene, β-carotene, β-cryptoxanthin, lycopene and lutein/zeaxanthin. There was no association between diet and plasma markers of retinol or vitamin E; this may reflect the importance of factors other than intake in modifying circulating levels of these nutrients.


2003 ◽  
Vol 28 (1) ◽  
pp. 79-92 ◽  
Author(s):  
Carole Groussard ◽  
Guillaume Machefer ◽  
Françoise Rannou ◽  
Henri Faure ◽  
Hassane Zouhal ◽  
...  

We tested seven physical education students whether 30-s sprint anaerobic exercise (Wingate test) would result in oxidative stress (evaluated by lipid radical levels) sufficient to alter plasma non-enzymatic antioxidant status (plasma uric acid, ascorbic acid, α-tocopherol, β-carotene). This study demonstrates that 1) Wingate test increases plasma uric and ascorbic acid concentrations (p < .05), and decreases plasma α-tocopherol and β-carotene levels (p < .05); 2) lipid radical levels at rest and sprint performance are negatively correlated with resting plasma uric acid and α-tocopherol concentrations (p < .05). In conclusion, this study 1) demonstrates that a 30-s sprint anaerobic exercise is associated with acute changes in plasma non-enzymatic antioxidant status, 2) indicates that the subjects with largest leg peak power are those who exhibit the lowest plasma antioxidant status at rest (uric acid and α-tocopherol), 3) and suggests that antioxidant intake by maintaining plasma antioxidant concentration at rest in the normal range might protect athletes against oxidative stress induced by exercise. Key words: ascorbic acid, α-tocopherol, β-carotene, uric acid, oxidative stress


2002 ◽  
Vol 33 (3) ◽  
pp. 276-280 ◽  
Author(s):  
Giyasettin Baydas ◽  
Fikret Karatas ◽  
M.Ferit Gursu ◽  
H.Ayse Bozkurt ◽  
Nevin Ilhan ◽  
...  

2020 ◽  
Vol 20 (1) ◽  
pp. 287-298 ◽  
Author(s):  
Aneta Brodziak ◽  
Jolanta Król ◽  
Joanna Barłowska ◽  
Zygmunt Litwińczuk ◽  
Anna Teter ◽  
...  

AbstractThe aim of the study was to compare the content of selected bioactive whey proteins and lipophilic vitamins, which largely determine the bioactive status of milk, in milk obtained from local breeds of cows raised in Poland (Polish Red, White-Backed and Simmental) and Polish Holstein-Friesian cows. Basic chemical composition and content of selected bioactive compounds (β-lactoglobulin, α-lactalbumin, lactoferrin, bovine serum albumin, and vitamins: E, A, D3 and β-carotene) in 550 milk samples were analysed. The milk produced by local breeds proved to be a more valuable source of whey proteins and lipophilic vitamins than that of the Polish Holstein-Friesians. It was distinguished by its content of all bioactive compounds, including those with antioxidant properties, i.e. vitamins E, A and D3 and β-lactoglobulin, and antimicrobial properties, mainly lactoferrin. Therefore, the milk of cows of local breeds should be considered a valuable material for processing, especially at the level of the farm or small local processing plant, to produce products that are richer in health-promoting compounds. The promotion of milk from local breeds can therefore be an opportunity for the farms that raise them.


2006 ◽  
Vol 96 (S1) ◽  
pp. S38-S41 ◽  
Author(s):  
Josep Tur-Marí ◽  
Antoni Sureda ◽  
Antoni Pons

Antioxidants have shown beneficial effects in several biological systems, in which they were able to prevent oxidative stress-associated damage. Vitamins C and E are key antioxidants in man. Dietary intake cannot accurately reflect plasma vitamin levels. However, the plasma levels of antioxidant vitamins could also reflect the acute assimilation of these vitamins. It has been pointed out that antioxidant vitamin blood contents reach a saturation level by intake of dietary supplements. Antioxidant vitamin plasma levels are the parameter most used to determine antioxidant status. However, the vitamin plasma levels may not reflect the nutritional status of vitamins. It has been pointed out that the vitamin E in adipose tissue can be used as a measure of vitamin E status. To determinate antioxidant vitamin contents in lymphocytes and neutrophils after exercise is a useful tool to assess the functional status of antioxidant vitamins.


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