scholarly journals Risk factors associated with postoperative morbidity and mortality in D2 radical gastrectomy for gastric cancer

2021 ◽  
Author(s):  
O.R. Paredes-Torres ◽  
L. García-Ruiz ◽  
J. Luna-Abanto ◽  
K. Meza-García ◽  
I. Chávez- Passiuri ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Postoperative Morbidity ◽  
Morbidity And Mortality ◽  
Radical Gastrectomy ◽  
Factors Associated

Risk factors associated with early postoperative complications following laparoscopic total gastrectomy: Experience from the Chinese Laparoscopic Gastrointestinal Surgery Study (CLASS) group.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e15544-e15544
Author(s):  
Jingdong Liu ◽  
Haojie Li ◽  
Gang Zhao ◽  
Zekuan Xu ◽  
Guoxin Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Postoperative Complications ◽  
Total Gastrectomy ◽  
Multivariable Analysis ◽  
Laparoscopic Total Gastrectomy ◽  
Morbidity And Mortality ◽  
Reconstruction Method ◽  
Factors Associated ◽  
Early Postoperative Complications

e15544 Background: The incidence rate of proximal gastric cancer has been rising steadily, and laparoscopic total gastrectomy (LTG) has been widely adopted. However, the safety of LTG still lacks solid evidence to prove. The aim of this study was to evaluate morbidity and mortality of LTG, and determine the risk factors associated with early postoperative complications. Methods: A retrospective multicenter study was carried out in China, and medical records of 109 gastric cancer patients receiving LTG during September 2014 and June 2016 were retrieved from the database. Patient characteristics, surgical outcomes, and postoperative morbidities and mortalities were analyzed. Results: Morbidity and mortality rates were 22.0% and 0% respectively. Pulmonary infection (13.8%, n = 15) was the most common complication. Most complications were grade II (15.5%, n = 17) according to the Clavien-Dindo classification. Multivariable analysis identified comorbidity, type of reconstruction method (TLTG) were independent risk factors of early postoperative complications. Comorbidity was the only independent risk factor of complications graded more than II. Diabetes mellitus was found correlated with surgical complication in subgroup analysis. Conclusions: LTG is safe and technically feasible in treating gastric cancer. Careful selection of patients without comorbidity and applying laparoscopy-assisted total gastrectomy instead of totally laparoscopic total gastrectomy may decrease postoperative complications.

Risk Factors for Reoperation Following Radical Gastrectomy in Gastric Cancer Patients

2021 ◽  
pp. 000313482110508
Author(s):  
Dong-Hwan Kim ◽  
Ji-Ho Park ◽  
Tae Han Kim ◽  
Eun-Jung Jung ◽  
Chi-Young Jeong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Small Bowel ◽  
Small Bowel Obstruction ◽  
Bowel Obstruction ◽  
Radical Gastrectomy ◽  
Factors Associated ◽  
Abdominal Bleeding ◽  
Independent Risk Factors ◽  
Gastric Cancer Patients

Background Reoperation due to elective surgery complications is very mentally, physically, and economically detrimental to patients. This study investigated the potential risk factors associated with early reoperation after radical gastrectomy in gastric cancer patients and included an in-depth analysis of these risk factors. Methods This retrospective study reviewed 1568 patients with gastric cancer. Grade 3 or greater complications were defined as severe. Any factors related to reoperation after radical gastrectomy were analyzed in patients with severe local complications. Results Among 1537 patients undergoing radical gastrectomy, 115 (7.5%) patients had severe postoperative complications, 98 (6.38%) of whom experienced severe local complications. The most common local complication was anastomotic leakage (31, 2.02%), followed by intra-abdominal abscess (30, 1.95%), pancreatic leakage (22, 1.43%), duodenal stump leakage (18, 1.17%), intra-abdominal bleeding (12, .78%), intraluminal bleeding (8, .52%), small bowel obstruction (5, .32%), and chyle leakage (3, .19%). Of these patients, 26 (1.69%) underwent reoperation, and 6 (.39%) died. In the univariate analysis of clinical factors related to reoperation, intra-abdominal bleeding and small bowel obstruction were risk factors for reoperation, and intra-abdominal bleeding (odds ratio [OR] = 9.57, confidence interval [CI] = 2.65-40.20, P < .001) and small bowel obstruction (OR = 19.14, CI = 2.60-390.13, P = .011) were independent risk factors associated with reoperation in the multivariate analysis. Conclusion Intra-abdominal bleeding and small bowel obstruction are independent risk factors for reoperation following radical gastrectomy. Patients with postoperative intra-abdominal bleeding and small bowel obstruction need to be warned about reoperation.

scholarly journals Analysis of postoperative morbidity and mortality following surgery for gastric cancer. Surgeon volume as the most significant prognostic factor

2017 ◽  
Vol 3 ◽  
pp. 215-221 ◽  
Author(s):  
Maciej Ciesielski ◽  
Wiesław J. Kruszewski ◽  
Jakub Walczak ◽  
Mariusz Szajewski ◽  
Jarosław Szefel ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Prognostic Factor ◽  
Postoperative Morbidity ◽  
Surgeon Volume ◽  
Morbidity And Mortality ◽  
Significant Prognostic Factor

scholarly journals Risk factors associated with the development of gastric cancer — case-control study

2018 ◽  
Vol 64 (7) ◽  
pp. 611-619 ◽  
Author(s):  
Marcus Fernando Kodama Pertille Ramos ◽  
Ulysses Ribeiro Júnior ◽  
Juliana Kodaira Yukari Viscondi ◽  
Bruno Zilberstein ◽  
Ivan Cecconello ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Cancer Case ◽  
Gastric Cancer Case ◽  
Factors Associated ◽  
Control Study ◽  
Development Of Gastric Cancer

scholarly journals Preoperative leukocytosis and the resection severity index are independent risk factors for survival in patients with intrahepatic cholangiocarcinoma

2020 ◽  
Vol 405 (7) ◽  
pp. 977-988
Author(s):  
Oliver Beetz ◽  
Clara A. Weigle ◽  
Sebastian Cammann ◽  
Florian W. R. Vondran ◽  
Kai Timrott ◽  
...  
Keyword(s):  
Risk Factors ◽  
Prognostic Factors ◽  
Postoperative Complications ◽  
Intrahepatic Cholangiocarcinoma ◽  
Postoperative Morbidity ◽  
Severity Index ◽  
The Body ◽  
Morbidity And Mortality ◽  
Independent Risk Factors ◽  
Risk Factors For Survival

Abstract Purpose The incidence of intrahepatic cholangiocarcinoma is increasing worldwide. Despite advances in surgical and non-surgical treatment, reported outcomes are still poor and surgical resection remains to be the only chance for long-term survival of affected patients. The identification and validation of prognostic factors and scores, such as the recently introduced resection severity index, for postoperative morbidity and mortality are essential to facilitate optimal therapeutic regimens. Methods This is a retrospective analysis of 269 patients undergoing resection of histologically confirmed intrahepatic cholangiocarcinoma between February 1996 and September 2018 at a tertiary referral center for hepatobiliary surgery. Regression analyses were performed to evaluate potential prognostic factors, including the resection severity index. Results Median postoperative follow-up time was 22.93 (0.10–234.39) months. Severe postoperative complications (≥ Clavien-Dindo grade III) were observed in 94 (34.9%) patients. The body mass index (p = 0.035), the resection severity index (ASAT in U/l divided by Quick in % multiplied by the extent of liver resection graded in points; p = 0.006), additional hilar bile duct resection (p = 0.005), and number of packed red blood cells transfused during operation (p = 0.036) were independent risk factors for the onset of severe postoperative complications. Median Kaplan-Meier survival after resection was 27.63 months. Preoperative leukocytosis (p = 0.003), the resection severity index (p = 0.005), multivisceral resection (p = 0.001), and T stage ≥ 3 (p = 0.013) were identified as independent risk factors for survival. Conclusion Preoperative leukocytosis and the resection severity index are useful variables for preoperative risk stratification since they were identified as significant predictors for postoperative morbidity and mortality, respectively.

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