Daily uptake of mycotoxins – TDI might not be protective for nursed infants

2017 ◽  
Vol 277 ◽  
pp. 69-75 ◽  
Author(s):  
G.H. Degen ◽  
F. Partosch ◽  
K. Muñoz ◽  
U. Gundert-Remy
Keyword(s):  
Daily Uptake

Mineral Composition of Drinking Water and Daily Uptake

2019 ◽  
pp. 25-32
Author(s):  
Bengt Nihlgård ◽  
Ingegerd Rosborg ◽  
Margherita Ferrante
Keyword(s):  
Drinking Water ◽  
Mineral Composition ◽  
Daily Uptake

Uptake by man of aluminium in a public water supply

1998 ◽  
Vol 17 (6) ◽  
pp. 296-301 ◽  
Author(s):  
N D Priest ◽  
R J Talbot ◽  
D Newton ◽  
J P Day ◽  
S J King ◽  
...  
Keyword(s):  
Gamma Ray ◽  
Tap Water ◽  
Young Male ◽  
Gamma Ray Spectrometry ◽  
Public Water Supply ◽  
Intestinal Uptake ◽  
Blood Samples ◽  
Al Content ◽  
Daily Uptake ◽  
Overnight Fasting

1 After overnight fasting, two young male adults each received a single oral dose of 100 Bq 26Al in tap water. Coincidence gamma-ray spectrometry and accelerator mass spectrometry were used to determine the 26Al content of excretion collections and of blood samples. 2 Close to 100% of the intake was recovered in faeces during the first 7 days. Gastro-intestinal uptake, determined by comparing urinary excretion with patterns previously established following intravenous administration of 26Al, averaged 0.22% in the two subjects. 3 Uptake fractions based on comparisons of blood concentration following ingestion and injection were much lower, but were judged to be unreliable. It is concluded that aluminium present in most water supplies is unlikely to contribute as much as 1% of a typical daily uptake of 10 mg from food.

Ontogenetic development of nutrient transporters in bullfrog intestine

1990 ◽  
Vol 258 (5) ◽  
pp. G760-G769 ◽  
Author(s):  
E. M. Toloza ◽  
J. M. Diamond
Keyword(s):  
Molecular Weight ◽  
Amino Acid ◽  
Daily Intake ◽  
Shift Function ◽  
Dietary Carbohydrate ◽  
Uptake Capacity ◽  
Protein Ratio ◽  
Intestinal Brush Border ◽  
Daily Uptake ◽  
Thin Walled

The ratio of intestinal glucose (Glc) to amino acid (AA) transporter activity rises with age in animals of species in which the ratio of dietary carbohydrate to protein also rises. Does this shift function to match transporter activity to current dietary substrate levels or to the high AA requirements of young growing animals? We compared intestinal brush-border uptake of Glc and the AA proline (Pro) in adult and tadpole bullfrogs, since with age this species changes from an herbivore to a carnivore and hence its dietary carbohydrate-to-protein ratio decreases rather than increases. Like typical adult herbivores, tadpoles have a long, highly coiled, narrow-bore, thin-walled intestine with a long, heavy colon, whereas adult bullfrogs have a short, wide-bore, thick-walled intestine typical of carnivores. The ratio of Glc to Pro uptake capacity is essentially the same in adults as in larval tadpoles and is typical of carnivores but unprecedently low for herbivores. This suggests that both functions proposed for developmental shifts of Glc and AA transport in other species are significant and that their effects cancel each other in bullfrogs. Transporter kinetic constants vary predictably with developmental stage. Intestinal daily uptake capacity is comparable to actual daily intake for Glc in adults and for Pro in both tadpoles and adults but is much lower than intake for Glc in tadpoles, probably because most carbohydrate ingested by tadpoles is in the form of high molecular weight polymers that are not utilized.

scholarly journals Daily Uptake of Biotin by the Hen’s Egg

1948 ◽  
Vol 27 (6) ◽  
pp. 823-825 ◽  
Author(s):  
J.R. Couch ◽  
W.W. Cravens ◽  
C.A. Elvehjem ◽  
J.G. Halpin
Keyword(s):  
Hen’S Egg ◽  
Daily Uptake

scholarly journals Mobile Biomonitoring of Atmospheric Pollution: A New Perspective for the Moss-Bag Approach

Plants ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 2384
Author(s):  
Maria Cristina Sorrentino ◽  
Fiore Capozzi ◽  
Karen Wuyts ◽  
Steven Joosen ◽  
Valentine K. Mubiana ◽  
...  
Keyword(s):  
Previous Experiment ◽  
Mobile System ◽  
Element Fluxes ◽  
Green Route ◽  
Icp Ms ◽  
Daily Uptake ◽  
New Perspective ◽  
Pm2.5 And Pm10 ◽  
First Time ◽  
Moss Bags

In this work the potential of moving moss-bags, fixed to bicycles, to intercept particulate matter (PM) and linked metal(loid)s was tested for the first time. Seven volunteers carried three moss-bags for fifty days while commuting by bicycle in the urban area of Antwerp, Belgium. Moreover, one bike, equipped with mobile PM samplers, travelled along four routes: urban, industrial, green route and the total path, carrying three moss-bags at each route. The saturation isothermal remanent magnetization (SIRM) signal and chemical composition (assessed by HR-ICP-MS) of the moss samples indicated that the industrial route was the most polluted. Element fluxes (i.e., the ratio between element daily uptake and the specific leaf area) could discriminate among land uses; particularly, they were significantly higher in the industrial route for Ag, As, Cd and Pb; significantly lowest in the green route for As and Pb; and comparable for all accumulated elements along most urban routes. A comparison with a previous experiment carried out in the same study area using similar moss-bags at static exposure points, showed that the element fluxes were significantly higher in the mobile system. Finally, PM2.5 and PM10 masses measured along the four routes were consistent with element fluxes.

Synthesis of deoxynivalenol-3-ß-D-O-glucuronide for its use as biomarker for dietary deoxynivalenol exposure

2012 ◽  
Vol 5 (2) ◽  
pp. 127-132 ◽  
Author(s):  
P. Fruhmann ◽  
B. Warth ◽  
C. Hametner ◽  
F. Berthiller ◽  
E. Horkel ◽  
...  
Keyword(s):  
Glucuronic Acid ◽  
Animal Health ◽  
Acid Methyl Ester ◽  
Direct Determination ◽  
Fungal Species ◽  
Acid Methyl ◽  
Average Intake ◽  
Metabolic Products ◽  
Daily Uptake ◽  
Uptake Measurement

Trichothecene mycotoxins are prevalent toxic secondary metabolic products of several fungal species and pose a serious threat to human and animal health. Deoxynivalenol (DON) is known to undergo rapid metabolisation after uptake. The formed glucuronides are urinary excreted and could therefore serve as possible biomarkers for daily uptake measurement. So far human exposure to the major toxin DON was estimated from dietary average intake or by measurement of the parent toxin after hydrolysis. These approaches are indirect and time-consuming. Due to the clear demand for a direct determination method and lack of an available reference substance we synthesised DON-3-O-ö-D-glucuronide. The Königs-Knorr procedure using acetobromo-α-D-glucuronic acid methyl ester as glucuronyl-donor was optimised to produce the target compound in mg scale allowing subsequent characterisation via nuclear magnetic resonance and LC-MS/MS.

Mineral Composition of Drinking Water and Daily Uptake

2014 ◽  
pp. 25-31
Author(s):  
Ingegerd Rosborg ◽  
Bengt Nihlgård ◽  
Margherita Ferrante
Keyword(s):  
Drinking Water ◽  
Mineral Composition ◽  
Daily Uptake

scholarly journals Optimizing Water-Based Extraction of Bioactive Principles of Hawthorn: From Experimental Laboratory Research to Homemade Preparations

Molecules ◽  
2019 ◽  
Vol 24 (23) ◽  
pp. 4420 ◽  
Author(s):  
Phu Cao Ngoc ◽  
Laurent Leclercq ◽  
Jean-Christophe Rossi ◽  
Isabelle Desvignes ◽  
Jasmine Hertzog ◽  
...  
Keyword(s):  
Cyclotron Resonance ◽  
High Performance ◽  
Laboratory Research ◽  
Ion Cyclotron Resonance ◽  
Active Components ◽  
Water Infusion ◽  
Water Based ◽  
Daily Uptake ◽  
Experimental Laboratory ◽  
Kinetics Of

Hawthorn (Crataegus) is used for its cardiotonic, hypotensive, vasodilative, sedative, antiatherosclerotic, and antihyperlipidemic properties. One of the main goals of this work was to find a well-defined optimized extraction protocol usable by each of us that would lead to repeatable, controlled, and quantified daily uptake of active components from hawthorn at a drinkable temperature (below 60 °C). A thorough investigation of the extraction mode in water (infusion, maceration, percolation, ultrasounds, microwaves) on the yield of extraction and the amount of phenolic compounds, flavonoids, and proanthocyanidin oligomers as well as on the Ultra High Performance Liquid Chromatography (UHPLC) profiles of the extracted compounds was carried out. High-resolution Fourier transform ion cyclotron resonance mass spectrometry was also implemented to discriminate the different samples and conditions of extraction. The quantitative and qualitative aspects of the extraction as well as the kinetics of extraction were studied, not only according to the part (flowers or leaves), the state (fresh or dried), and the granulometry of the dry plant, but also the stirring speed, the temperature, the extraction time, the volume of the container (cup, mug or bowl) and the use of infusion bags.

scholarly journals Prophylactic Effect of Dietary Seaweed Fucoidan against Enteral Prion Infection

2007 ◽  
Vol 51 (6) ◽  
pp. 2274-2277 ◽  
Author(s):  
Katsumi Doh-ura ◽  
Tomoko Kuge ◽  
Miyuki Uomoto ◽  
Keiko Nishizawa ◽  
Yuri Kawasaki ◽  
...  
Keyword(s):  
Prion Diseases ◽  
Dose Range ◽  
Maximum Level ◽  
Prophylactic Effect ◽  
Prion Infection ◽  
Daily Uptake

ABSTRACT Dietary seaweed fucoidan delays the onset of disease of enterally infected mice with scrapie when given orally for 6 days after infection, but not when given before the infection. This effect was not modified at a tested fucoidan dose range and appeared to reach the maximum level at a concentration of 2.5% or less in feed. Daily uptake of fucoidan might be prophylactic against prion diseases caused by ingestion of prion-contaminated materials, although further evaluation of its pharmacology remains to be done.

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