Vaccine initiation and 3-dose series completion of 4vHPV vaccine among US insured males 2012–2016

Vaccine ◽  
2021 ◽  
Author(s):  
Kandace L. Amend ◽  
Bruce Turnbull ◽  
Li Zhou ◽  
Morgan A. Marks ◽  
Christine Velicer ◽  
...  
Keyword(s):  
Vaccine Initiation ◽  
Series Completion

Outreach and Reminders to Improve Human Papillomavirus Vaccination in an Integrated Primary Care System

2018 ◽  
Vol 57 (13) ◽  
pp. 1523-1531 ◽  
Author(s):  
Nora B. Henrikson ◽  
Weiwei Zhu ◽  
Lauren Baba ◽  
Matthew Nguyen ◽  
Heidi Berthoud ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Health System ◽  
Hpv Vaccine ◽  
Hpv Vaccination ◽  
Intervention Group ◽  
Human Papillomavirus Vaccination ◽  
Vaccine Initiation ◽  
Series Completion ◽  
And Control ◽  
The Impact

This study evaluated the impact of health system–based outreach and reminders on human papillomavirus (HPV) vaccine series initiation and completion. Parents of 10 to 12 year olds (n = 1805) were randomized to receive either (1) an outreach letter and brochure recommending HPV vaccination followed by automated HPV vaccine reminders or (2) usual care. We interviewed a subset of 50 parents to assess program acceptability. Outcomes were HPV vaccine initiation during the study period and on-time series completion. Rates of HPV vaccine initiation during the study period (July 2015 to August 2016) were similar between the intervention and control groups, but initiation within 120 days of randomization was higher in the intervention group (23.6% and 18.8%, P = .04) as was completion during the study period (10.3% vs 6.8%, P = .04). Reminders for doses 2 and 3 did not affect completion. The program was acceptable to parents. This study provides evidence that health system–based outreach and reminders can improve HPV vaccination.

HPV Vaccine Initiation and Completion Among Native Hawaiian and Pacific Islander Adults, United States, 2014

2021 ◽  
pp. 101053952110274
Author(s):  
Sameer Vali Gopalani ◽  
Amanda E. Janitz ◽  
Sydney A. Martinez ◽  
Janis E. Campbell ◽  
Sixia Chen
Keyword(s):  
United States ◽  
Logistic Regression ◽  
Vaccination Coverage ◽  
Hpv Vaccine ◽  
Regression Models ◽  
Insurance Coverage ◽  
Hpv Vaccination ◽  
Pacific Islander ◽  
Logistic Regression Models ◽  
Vaccine Initiation

Native Hawaiian and Pacific Islander (NHPI) adults bear a disproportionate burden of certain human papillomavirus (HPV)-associated cancers. In 2015, data from the National Health Interview Survey (NHIS) showed vaccination coverage among adults by racial and ethnic groups; however, coverage data for NHPI adults were unavailable. In this study, we estimated the initiation and completion of HPV vaccination and assessed the factors associated with vaccination among NHPI adults aged 18 to 26 years in the United States. We analyzed public data files from the 2014 NHPI NHIS (n = 1204). We specified sampling design parameters and fitted weighted logistic regression models to calculate the odds of HPV vaccine initiation. We developed a directed acyclic graph to identify a minimally sufficient set for adjustment and adjusted for insurance coverage (for education and ethnicity) and doctor visit (for insurance coverage, earnings, ethnicity, and sex). Overall, 24.9% and 11.5% of NHPI adults had initiated and completed the HPV vaccination series, respectively. Weighted logistic regression models elucidated that the odds of HPV vaccine initiation were higher for females (weighted odds ratio = 5.4; 95% confidence interval = 2.8-10.4) compared with males. Low vaccination coverage found among NHPI adults provides an opportunity for targeted programs to reduce the burden of HPV-associated cancers.

Vaccine Initiation Rate and Volatility in the International Stock Market during COVID-19

2021 ◽  
Author(s):  
Bao Cong Nguyen To ◽  
Bao Khac Quoc Nguyen ◽  
Tam Van Thien Nguyen ◽  
Phuong Thi Minh Nguyen
Keyword(s):  
Stock Market ◽  
Initiation Rate ◽  
Vaccine Initiation

scholarly journals Effectiveness of CoronaVac, ChAdOx1, BNT162b2 and Ad26.COV2.S among individuals with prior SARS-CoV-2 infection in Brazil

2021 ◽  
Author(s):  
Thiago Cerqueira-Silva ◽  
Jason R Andrews ◽  
Viviane S Boaventura ◽  
Otavio T Ranzani ◽  
Vinicius de Araujo Oliveira ◽  
...  
Keyword(s):  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Case Control ◽  
Rt Pcr ◽  
Symptomatic Infection ◽  
Series Completion ◽  
Negative Controls ◽  
Prior Infection ◽  
Control Study ◽  
Dose Vaccine

Background. COVID-19 vaccines have proven highly effective among SARS-CoV-2 naive individuals, but their effectiveness in preventing symptomatic infection and severe outcomes among individuals with prior infection is less clear. Methods. Utilizing national COVID-19 notification, hospitalization, and vaccination datasets from Brazil, we performed a case-control study using a test-negative design to assess the effectiveness of four vaccines (CoronaVac, ChAdOx1, Ad26.COV2.S and BNT162b2) among individuals with laboratory-confirmed prior SARS-CoV-2 infection. We matched RT-PCR positive, symptomatic COVID-19 cases with RT-PCR-negative controls presenting with symptomatic illnesses, restricting both groups to tests performed at least 90 days after an initial infection. We used multivariable conditional logistic regression to compare the odds of test positivity, and the odds of hospitalization or death due to COVID-19, according to vaccination status and time since first or second dose of vaccines. Findings. Among individuals with prior SARS-CoV-2 infection, vaccine effectiveness against symptomatic infection ≥ 14 days from vaccine series completion was 39.4% (95% CI 36.1-42.6) for CoronaVac, 56.0% (95% CI 51.4-60.2) for ChAdOx1, 44.0% (95% CI 31.5-54.2) for Ad26.COV2.S, and 64.8% (95% CI 54.9-72.4) for BNT162b2. For the two-dose vaccine series (CoronaVac, ChAdOx1, and BNT162b2), effectiveness against symptomatic infection was significantly greater after the second dose compared with the first dose. Effectiveness against hospitalization or death ≥ 14 days from vaccine series completion was 81.3% (95% CI 75.3-85.8) for CoronaVac, 89.9% (95% CI 83.5-93.8) for ChAdOx1, 57.7% (95% CI -2.6-82.5) for Ad26.COV2.S, and 89.7% (95% CI 54.3-97.7) for BNT162b2.

scholarly journals Effect of a Community-Based Hepatitis B Virus Infection Detection Combined with Vaccination Program in China

Vaccines ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 19
Author(s):  
Xinyao Liu ◽  
Wuqi Qiu ◽  
Yan Liang ◽  
Wei Zhang ◽  
Qian Qiu ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Vaccination Rate ◽  
Hepatitis B Vaccine ◽  
Hepatitis B Vaccination ◽  
Control Groups ◽  
Community Based ◽  
B Virus ◽  
Series Completion ◽  
And Control

Evidence on the effectiveness of hepatitis B virus (HBV) infection screening and vaccination programs remains rare in China. We used a quasi-experimental method, propensity score matching, to evaluate the effects of a community-based HBV infection detection combined with vaccination (HBVIDV) program in a pilot. Data were retrieved from the HBVIDV program implemented between July 2019 and June 2020. Outcomes were the difference between the treatment and control groups in hepatitis B vaccination (≥1 dose), hepatitis B vaccine series completion (≥3 doses), and serologic evidence of vaccine-mediated immunity. Altogether, 26,180 individuals were included, where 6160 (23.5%) individuals were assigned to the treatment group, and 20,020 (76.5%) individuals were assigned to the control group. After propensity score matching, 5793 individuals were matched. The rates of hepatitis B vaccination, hepatitis B vaccine series completion, and prevalence of vaccine-mediated immunity in the treatment and control groups were 29.0% vs. 17.8%, 22.1% vs. 13.1%, and 38.2% vs. 27.6%, respectively. The HBVIDV program was significantly associated with increased hepatitis B vaccination rate (OR, 1.884, 95% CI 1.725–2.057), hepatitis B vaccine series completion rate (OR, 1.872, 95% CI 1.696–2.065), and prevalence of vaccine-mediated immunity (OR, 1.623, 95% CI 1.501–1.755). The greater magnitude of association between HBVIDV program and outcomes was observed among adults aged 35–54 years and adults who live in rural areas. The HBVIDV program was effective in increasing the hepatitis B vaccination rate, hepatitis B vaccine series completion rate, and prevalence of vaccine-mediated immunity among adults in the pilot. Further focusing the program on special populations and regions may produce more effective results.

scholarly journals Personalized Reminders for Immunization Using Short Messaging Systems to Improve Human Papillomavirus Vaccination Series Completion: Parallel-Group Randomized Trial

10.2196/26356 ◽  
2021 ◽  
Vol 9 (12) ◽  
pp. e26356
Author(s):  
Chelsea S Wynn ◽  
Marina Catallozzi ◽  
Chelsea A Kolff ◽  
Stephen Holleran ◽  
Dodi Meyer ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Hpv Vaccine ◽  
Text Message ◽  
Text Messages ◽  
Completion Rates ◽  
Minority Adolescents ◽  
Group Randomized Trial ◽  
Series Completion ◽  
Historical Controls ◽  
Educational Information

Background Completion rates among adolescents who initiate the human papillomavirus (HPV) vaccine 3-dose series are low. SMS text message vaccine reminders are effective, but less is known about the best types for HPV series completion or the ability to assess and target vaccine decision-making stage. Objective The aim of this study is to compare the effectiveness of HPV vaccine series completion in minority adolescents who received precision and educational versus conventional SMS text message reminders. Methods Enrolled parents of adolescents aged 9-17 years who received the first HPV vaccine dose at 1 of the 4 academic-affiliated community health clinics in New York City were randomized 1:1 to 1 of the 2 parallel, unblinded arms: precision SMS text messages (which included stage-targeted educational information, next dose due date, and site-specific walk-in hours) or conventional SMS text messages without educational information. Randomization was stratified according to gender, age, and language. The primary outcome was series completion within 12 months. In post hoc analysis, enrollees were compared with concurrent nonenrollees and historical controls. Results Overall, 956 parents were enrolled in the study. The precision (475 families) and conventional (481 families) SMS text message arms had similarly high series completion rates (344/475, 72.4% vs 364/481, 75.7%). A total of 42 days after the first dose, two-thirds of families, not initially in the preparation stage, moved to preparation or vaccinated stage. Those in either SMS text message arm had significantly higher completion rates than nonenrollees (708/1503, 47.1% vs 679/1503, 45.17%; P<.001). Even after removing those needing only 2 HPV doses, adolescents receiving any SMS text messages had higher completion rates than historical controls (337/2823, 11.93% vs 981/2823, 34.75%; P<.001). A population-wide effect was seen from 2014 to 2016, above historical trends. Conclusions SMS text message reminders led to timely HPV vaccine series completion in a low-income, urban, minority study population and also led to population-wide effects. Educational information did not provide an added benefit to this population. Trial Registration ClinicalTrials.gov NCT02236273; https://clinicaltrials.gov/ct2/show/NCT02236273

scholarly journals Word Embeddings as Metric Recovery in Semantic Spaces

2016 ◽  
Vol 4 ◽  
pp. 273-286 ◽  
Author(s):  
Tatsunori B. Hashimoto ◽  
David Alvarez-Melis ◽  
Tommi S. Jaakkola
Keyword(s):  
Random Walks ◽  
Manifold Learning ◽  
State Of The Art ◽  
Inductive Reasoning ◽  
Semantic Space ◽  
Word Embedding ◽  
Word Embeddings ◽  
Recovery Algorithm ◽  
Series Completion ◽  
Semantic Spaces

Continuous word representations have been remarkably useful across NLP tasks but remain poorly understood. We ground word embeddings in semantic spaces studied in the cognitive-psychometric literature, taking these spaces as the primary objects to recover. To this end, we relate log co-occurrences of words in large corpora to semantic similarity assessments and show that co-occurrences are indeed consistent with an Euclidean semantic space hypothesis. Framing word embedding as metric recovery of a semantic space unifies existing word embedding algorithms, ties them to manifold learning, and demonstrates that existing algorithms are consistent metric recovery methods given co-occurrence counts from random walks. Furthermore, we propose a simple, principled, direct metric recovery algorithm that performs on par with the state-of-the-art word embedding and manifold learning methods. Finally, we complement recent focus on analogies by constructing two new inductive reasoning datasets—series completion and classification—and demonstrate that word embeddings can be used to solve them as well.

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