Why have ovarian cancer mortality rates declined? Part III. Prospects for the future

2015 ◽  
Vol 138 (3) ◽  
pp. 757-761 ◽  
Author(s):  
Victoria Sopik ◽  
Barry Rosen ◽  
Vasily Giannakeas ◽  
Steven A. Narod
1994 ◽  
Vol 23 (6) ◽  
pp. 1133-1136 ◽  
Author(s):  
ELLEN SCHNEIDER LEFKOWITZ ◽  
CEDRIC F GARLAND

2015 ◽  
Vol 138 (3) ◽  
pp. 741-749 ◽  
Author(s):  
Victoria Sopik ◽  
Javaid Iqbal ◽  
Barry Rosen ◽  
Steven A. Narod

2020 ◽  
Vol 9 (10) ◽  
pp. e5749108828
Author(s):  
Lander dos Santos ◽  
Igor Roszkowski ◽  
Amanda de Carvalho Dutra ◽  
Adriana Cunha Vargas Tomas ◽  
Fernando Castilho Pelloso ◽  
...  

Ovarian cancer is the eighth cause of death by cancer in women worldwide. The objective of this study was to analyze trends in the Brazilian ovarian cancer mortality and the relation to age, schooling, and race. Data was collected in the Brazilian Mortality Information System (SIM), from 2006 to 2016. The polynomial regression model was used for the trends analysis, a significant trend was considered when the estimated model obtained a p-value <0.05. Ovarian Cancer caused 34,003 deaths in Brazilian women in this period, the mortality rate (MR) was 0.46 per 100.000 women aged less than 40; 4.2 in women aged between 40 – 59; 12.2 in women aged between 60 – 79 and 19.4 in women 80 years old or more. About Race, 65% were White, others were declared as Black, Asian, Mixed-race, or Indigenous. Only 26% had 8 years or more of schooling. Mortality rates from ovarian cancer seemed to be rising in Brazil, the major increase happened in the South, the Southeast, and the Middle-West Regions. Women aged between 40 to 59 had the most significant increase. Politics are needed to facilitate the Brazilian population's access to health services, consequently minimizing the time to diagnose and start the treatment. Research about mortality rates could help health workers identify gaps in knowledge and consequently decrease the magnitude of the disease.


Medicina ◽  
2020 ◽  
Vol 56 (7) ◽  
pp. 347
Author(s):  
Rūta Everatt ◽  
Birutė Intaitė

Background: The corpus uteri and ovarian cancers burden in Lithuania has remained high. The aim of this study was to investigate time trends in mortality rates of corpus uteri and ovarian cancer in Lithuania across age groups and time periods over a 30-year time span. Materials and Methods: Data on numbers of deaths from corpus uteri cancer during the period 1987–2016 and ovarian cancer during the period 1993–2016 were obtained from the WHO mortality database. Trends in age-standardized mortality rates (ASR, world standard), and age-specific rates were analyzed by calculating annual percentage change using Joinpoint regression. In addition, age–period–cohort analysis was performed for each cancer type. Results: Mortality from corpus uteri cancer decreased by −1.2% (95% CI: −1.8; −0.7) annually from 1987 to 2016. Decrease was most pronounced in youngest age group of 40–49 years; annual percentage change was −2.4 (95% CI: −4.0; −0.9). Mortality rates for ovarian cancers decreased by −1.2% (95% CI: −1.6; −0.8) annually from 1993 to 2016. Corpus uteri and ovarian cancer ASRs in 2016 were 3.5/100,000 and 7.4/100,000, respectively. The age–period–cohort analysis suggests that temporal trends in corpus uteri cancer mortality rates could be attributed to period and cohort effects. Conclusion: A reduction in mortality rate was observed for corpus uteri and ovarian cancer over the entire study period. Similar decreasing pattern for corpus uteri and ovarian cancer mortality indicate effect of shared factors.


2013 ◽  
Vol 130 (1) ◽  
pp. e14-e15
Author(s):  
A. Melamed ◽  
J. Rauh-Hain ◽  
R. Clark ◽  
L. Bradford ◽  
A. Goodman ◽  
...  

2015 ◽  
Vol 138 (3) ◽  
pp. 750-756 ◽  
Author(s):  
Victoria Sopik ◽  
Javaid Iqbal ◽  
Barry Rosen ◽  
Steven A. Narod

2010 ◽  
Vol 28 (15) ◽  
pp. 2625-2634 ◽  
Author(s):  
Malcolm A. Smith ◽  
Nita L. Seibel ◽  
Sean F. Altekruse ◽  
Lynn A.G. Ries ◽  
Danielle L. Melbert ◽  
...  

Purpose This report provides an overview of current childhood cancer statistics to facilitate analysis of the impact of past research discoveries on outcome and provide essential information for prioritizing future research directions. Methods Incidence and survival data for childhood cancers came from the Surveillance, Epidemiology, and End Results 9 (SEER 9) registries, and mortality data were based on deaths in the United States that were reported by states to the Centers for Disease Control and Prevention by underlying cause. Results Childhood cancer incidence rates increased significantly from 1975 through 2006, with increasing rates for acute lymphoblastic leukemia being most notable. Childhood cancer mortality rates declined by more than 50% between 1975 and 2006. For leukemias and lymphomas, significantly decreasing mortality rates were observed throughout the 32-year period, though the rate of decline slowed somewhat after 1998. For remaining childhood cancers, significantly decreasing mortality rates were observed from 1975 to 1996, with stable rates from 1996 through 2006. Increased survival rates were observed for all categories of childhood cancers studied, with the extent and temporal pace of the increases varying by diagnosis. Conclusion When 1975 age-specific death rates for children are used as a baseline, approximately 38,000 childhood malignant cancer deaths were averted in the United States from 1975 through 2006 as a result of more effective treatments identified and applied during this period. Continued success in reducing childhood cancer mortality will require new treatment paradigms building on an increased understanding of the molecular processes that promote growth and survival of specific childhood cancers.


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