Fr281 IMPACT OF LIXISENATIDE ON MYOELECTRIC GASTRIC ACTIVITY ASSESSED BY ELECTROGASTROGRAPHY IN EXPERIMENTAL PIGS

Aggression seen on mixing of young pigs is a major welfare concern in modern farming. One solution may be to reduce the likelihood of aggression within a group by using combinations of individuals that facilitate rapid integration. This idea has been investigated by Mendl and Erhard (1997) using pigs with various levels of aggressiveness. An attack latency test was used to measure individual aggressiveness. Experimental pigs were placed in a familiar pen with an unfamiliar pig and the time taken to attack (i.e. attempt to fight) the intruder measured. In a substantial number of tests (e.g. 61% in the present study) no attack occurs in the time allowed (5 minutes) These pigs vary in their interactions with the intruder, ranging from no interest at all to persistent interest with isolated aggressive acts but no escalation to fighting (personal observation). The aim of this study was to investigate social behaviour throughout the test, thereby allowing a more detailed analysis of aggressiveness to be made.

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Evaluation of an enzymatically treated soya protein in the diet of weaned pigs

Proceedings of the British Society of Animal Production (1972) ◽

10.1017/s0308229600027057 ◽

1994 ◽

Vol 1994 ◽

pp. 160-160

Author(s):

C A Weeks ◽

BG Miller ◽

L Green ◽

S Rizvi ◽

C Beck ◽

...

Keyword(s):

Milk Proteins ◽

Protein Isolate ◽

Soya Protein ◽

Test Diet ◽

Soya Protein Isolate ◽

Commercial Farms ◽

Main Protein ◽

Soya Proteins ◽

Set Up ◽

Experimental Pigs

Soya proteins can provoke an immune response and cause diarrhoea in pigs weaned at 3 weeks of age. An enzymatically treated soya protein isolate (NURISH protein) did not have these effects in isolator reared experimental pigs (Miller et al 1992). A blind trial on 4 commercial farms was set up to evaluate NURISH as an alternative to conventional protein sources.On each farm 120 pigs (in 2 or 3 replicates) were fed either a typical commercial weaner diet containing cereals, fishmeal, milk proteins and full fat soya (the control) or a test diet matched for protein (22% CP), lysine (1.6%) and energy (DE 15.1 MJ/kg) with NURISH as the main protein source. Prophylactic antibiotics were not used.

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Inhaled Feed Particles in Experimental Pigs with and without Vitamin A Deficiency

Veterinary Pathology ◽

10.1177/0300985875012005-00608 ◽

1975 ◽

Vol 12 (5-6) ◽

pp. 415-427

Author(s):

K. W. F. Jericho

Keyword(s):

Vitamin A ◽

Salivary Glands ◽

Giant Cell ◽

Respiratory Disease ◽

Alveolar Macrophages ◽

Vitamin A Deficiency ◽

Respiratory Epithelium ◽

Dust Exposure ◽

Distinguishing Features ◽

Experimental Pigs

An attempt was made to experimentally reproduce an unusual respiratory disease of pigs fed a dusty mixture of finely ground peas, wheat, and barley. Groups of vitamin-A-deficient piglets from this herd were either given dry feed and daily exposure to dust from the feed or were given wet feed. Vitamin-A-fortified pigs of another stock were also given the dry feed and dust exposure. The upper and lower respiratory tracts, renal pelves, and interlobular ducts of salivary glands were studied histologically. The distinguishing features of lungs were starch particles from feed (up to 31.2 μm in diameter) in all lungs (but more in lungs of pigs given dry feed), free alveolar macrophages, giant cell formations, and mild degenerative processes of respiratory epithelium. The epithelium of most renal pelves was marked by mucinous degeneration.

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Sa1339 Effect of Different Doses of Atropine on the Gastric Myoelectric Activity in Experimental Pigs

Gastroenterology ◽

10.1016/s0016-5085(14)60941-0 ◽

2014 ◽

Vol 146 (5) ◽

pp. S-267 ◽

Cited By ~ 1

Author(s):

Jan Bures ◽

Jaroslav Kvetina ◽

Michal Pavlik ◽

Martin Kunes ◽

Kamil Kuca ◽

...

Keyword(s):

Myoelectric Activity ◽

Gastric Myoelectric Activity ◽

Different Doses ◽

Experimental Pigs

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Improved myocardial performance induced by dofibrate during reperfusion after acute myocardial infarction

Canadian Journal of Physiology and Pharmacology ◽

10.1139/y88-248 ◽

1988 ◽

Vol 66 (12) ◽

pp. 1518-1523 ◽

Cited By ~ 15

Author(s):

M. Renuka Prasad ◽

Ronald Clement ◽

Hajime Otani ◽

Randall Jones ◽

Dipak K. Das ◽

...

Keyword(s):

Fatty Acids ◽

Myocardial Injury ◽

Left Ventricular ◽

Ischemia And Reperfusion ◽

Cardioplegic Arrest ◽

Beneficial Effects ◽

Hypolipidemic Drug ◽

And Control ◽

Experimental Pigs

The increase of cellular fatty acids appears to be one of the causes of the myocardial injury during ischemia and reperfusion. This study was designed to examine whether a hypolipidemic drug such as clofibrate can reduce the myocardial injury during ischemia and reperfusion. Clofibrate was fed to experimental pigs for 9 days. Isolated in situ hearts from both experimental and control pigs were subjected to 60 min of regional ischemia induced by occluding the left anterior descending coronary artery, followed by 60 min of global ischemia by hypothermic cardioplegic arrest and 60 min of reperfusion. The clofibrate feeding resulted in the better cardiac performance as judged by increased coronary blood flow, improved left ventricular function, and reduced myocardial injury as judged by creatine kinase release. Although the clofibrate-fed animals contained higher levels of thiobarbituric reactive materials, the free fatty acid levels of plasma and myocardium were much lower compared with control animals. The clofibrate feeding was also associated with increased peroxisomal catalase and (β-oxidation of fatty acids. These results suggest that decreased levels of free fatty acids in the plasma and the myocardium and increased catalase activity induced by antilipolytic therapy appear to provide beneficial effects to the myocardium during ischemia and reperfusion.

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Age-Appropriateness of Porcine Models Used for Cell Transplantation

Cell Transplantation ◽

10.1177/0963689718817477 ◽

2018 ◽

Vol 28 (2) ◽

pp. 224-228 ◽

Cited By ~ 5

Author(s):

Shugo Tohyama ◽

Eiji Kobayashi

Keyword(s):

Body Size ◽

Animal Models ◽

Cell Therapy ◽

Cell Transplantation ◽

Preclinical Trials ◽

Experimental Pigs

Pigs have traditionally been used for preclinical experiments, and body size-matching is important for cell therapy in animal models used for preclinical trials. It has been shown that the efficacy of the transplanted cells is dependent on the response of the host heart and the age of experimental pigs.

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