Radiation Therapy: A Primary Treatment Modality for Seminoma

1980 ◽  
Vol 7 (3) ◽  
pp. 757-764
Author(s):  
Ray E. Stutzman ◽  
David G. McLeod
Keyword(s):  
Radiation Therapy ◽  
Treatment Modality ◽  
Primary Treatment ◽  
Primary Treatment Modality

scholarly journals Role of Adjuvant Radiosurgery after Thoracoscopic Microsurgical Resection of a Spinal Schwannoma

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Toba N. Niazi ◽  
Christian A. Bowers ◽  
Meic H. Schmidt
Keyword(s):  
Stereotactic Radiosurgery ◽  
Treatment Modality ◽  
Surgical Excision ◽  
Primary Treatment ◽  
Benign Tumors ◽  
Noninvasive Treatment ◽  
Thoracic Spinal ◽  
Primary Treatment Modality ◽  
Microsurgical Resection ◽  
Spinal Schwannoma

Stereotactic radiosurgery to benign tumors of the spine has not been advocated as a primary treatment modality because of the favorable prognosis for these lesions after gross-total resection. There is even less evidence regarding its use as an adjuvant to neurosurgical resection of benign recurrent spinal disease. We describe the case of a 30-year-old man with a thoracic spinal schwannoma who had an interval increase of his lesion five months after thoracoscopic microsurgical resection. The patient opted for noninvasive stereotactic radiosurgery in lieu of additional surgical excision and has had stable disease 15 months after radiosurgical treatment with the linear accelerator (LINAC) system. In this setting, stereotactic radiosurgery provided a useful adjunct to thoracoscopic microsurgical resection. Future Class I and II evidence should be sought to evaluate the utility of stereotactic radiosurgery as a primary treatment modality or as an adjuvant for microneurosurgical resection of benign spinal lesions in patients who want noninvasive treatment after disease recurrence or who harbor medical comorbidities that would preclude them from being safe surgical candidates.

Glossopharyngeal Neuralgia

2019 ◽  
pp. 23-30
Author(s):  
Oren Sagher
Keyword(s):  
Weight Loss ◽  
Trigeminal Neuralgia ◽  
Microvascular Decompression ◽  
Medical Management ◽  
Treatment Modality ◽  
Primary Treatment ◽  
Glossopharyngeal Neuralgia ◽  
Pain Condition ◽  
Primary Treatment Modality ◽  
Posterior Tongue

Glossopharyngeal neuralgia is an uncommon, but devastating pain condition. It shares many features with trigeminal neuralgia, but predominantly affects the posterior tongue and pharynx. Since glossopharyngeal neuralgia pain is frequently triggered by swallowing or movement of the tongue, patients frequently present with weight loss and dehydration. This chapter describes the classic features of this condition, including its association with syncope. The medical management of glossopharyngeal neuralgia is outlined as a primary treatment modality. Surgical considerations are also described, including microvascular decompression or sectioning of the glossopharyngeal nerve. Surgical pearls for both of these procedures are outlined, as well as strategies for complication avoidance and management.

Symptom burden among head and neck cancer patients in the first year after diagnosis: Association with primary treatment modality

Oral Oncology ◽  
2019 ◽  
Vol 99 ◽  
pp. 104434 ◽  
Author(s):  
Catherine O. Allen-Ayodabo ◽  
Antoine Eskander ◽  
Laura E. Davis ◽  
Haoyu Zhao ◽  
Alyson L. Mahar ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Treatment Modality ◽  
Symptom Burden ◽  
Primary Treatment ◽  
First Year ◽  
Primary Treatment Modality

Utility of prostate multiparametric MRI (mpMRI) for recurrent prostate cancer after radiation therapy and cryotherapy.

2016 ◽  
Vol 34 (2_suppl) ◽  
pp. 71-71
Author(s):  
Evan Kovac ◽  
Andrei Purysko ◽  
J. Stephen Jones ◽  
Cristina Magi-Galluzzi ◽  
Eric A. Klein ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radiation Therapy ◽  
Prostate Biopsy ◽  
Prostate Volume ◽  
Univariate Analysis ◽  
Primary Treatment ◽  
Recurrent Prostate Cancer ◽  
Positive Biopsy ◽  
Primary Treatment Modality ◽  
Locally Recurrent

71 Background: We evaluated the accuracy of mpMRI for identifying locally recurrent prostate cancer after primary radiotherapy and cryotherapy. Methods: Between 2009-2015, 61 patients with evidence of rising PSA after external-beam radiotherapy (EBRT) (N = 33), brachytherapy (N = 6), and cryotherapy (N = 22) were evaluated for locally recurrent prostate cancer with mpMRI and prostate biopsy. Of these patients, 6 (10%) received androgen deprivation therapy (ADT) in combination with EBRT for a median of 24 months. Three of the cryotherapy patients received prior EBRT. Patients were identified from a prospective mpMRI database. All patients with a lesion of interest (LOI) underwent a ≥ 12-core, post-mpMRI cognitive fusion prostate biopsy. We excluded 16 patients with mpMRI who did not undergo prostate biopsy (5 positive, 11 negative). Results: Median age was 70 (IQR: 64-77). The median time from primary treatment to mpMRI was 5 years (IQR: 3-9) and the median PSA at mpMRI was 3.6 ng/mL (IQR: 2.1-5.5). Median prostate volume was 18.8 cc (IQR: 11.0-28.0 cc). mpMRI revealed lesions of interest (LOI) in 39 (64%) and 41 (67%) had biopsy-proven local recurrence. Of the 22 patients with negative mpMRI, 8 (36%) had a positive biopsy, with a median prostate volume of 19 cc, median maximum cancer length of 5 mm, median PSA of 2.5 and biopsy Gleason scores 3+3 (N = 1), 4+3 (N=2), 5+4 (N = 1), 5+5 (N = 1) and ungraded due to treatment effect (N = 3). Of the 39 patients with LOI on mpMRI, 33 (85%) had a positive biopsy. Table 1 summarizes the mpMRI and biopsy results. The sensitivity, specificity, PPV and NPV of mpMRI to predict cancer diagnosis at biopsy was 80.5%, 70.0%, 84.6% and 63.6%, respectively. On univariate analysis, gland size (p=0.367), PSA (p=0.872), biopsy Gleason score (p=0.892) and primary treatment modality (p=0.177) did not significantly predict discrepancy between mpMRI and biopsy findings. Conclusions: mpMRI reliably identifies prostate cancer recurrence after primary radiation therapy and cryoablation. [Table: see text]

Juvenile Nasopharyngeal Angiofibroma

1978 ◽  
Vol 87 (5) ◽  
pp. 630-632 ◽  
Author(s):  
Hugh F. Biller
Keyword(s):  
Surgical Resection ◽  
Clinical Examination ◽  
Adjunctive Therapy ◽  
Treatment Modality ◽  
Primary Treatment ◽  
Juvenile Nasopharyngeal Angiofibroma ◽  
X Rays ◽  
Arterial Ligation ◽  
Nasopharyngeal Angiofibroma ◽  
Primary Treatment Modality

The diagnosis of angiofibroma can be suspected in most cases by clinical examination, supplemented by routine x-rays and tomograms and is confirmed by angiography. Adjunctive therapy including embolization, estrogens, cryotherapy and arterial ligation is discussed. Surgical resection is the preferred treatment. Radiotherapy as the primary treatment modality is contra-indicated except in select cases.

scholarly journals Role of punctal plugs as a primarily treatment modality in moderate to severe dry eye

2020 ◽  
Vol 7 (2) ◽  
pp. 72
Author(s):  
Sonali V. Kumar
Keyword(s):  
Dry Eye ◽  
Treatment Modality ◽  
Primary Treatment ◽  
Punctal Plugs ◽  
Primary Treatment Modality ◽  
Staining Score ◽  
Group A ◽  
Eye Symptoms ◽  
Group B ◽  
Dry Eye Symptoms

<p class="abstract"><strong>Background:</strong> In dry eye syndrome tear film disrupts which lead to ocular discomfort. Treatment of dry eye is very challenging and time consuming. Multiple treatment options are available for treating dry eye and one of them is punctal plugs. It blocks the drainage of tear by occluding puncta which helps in the preservation of natural tears on the ocular surface and relieve dry eye symptoms. This study was conducted to assess the safety and efficacy of punctal plugs as a primary treatment modality in moderate to severe dry eye.</p><p class="abstract"><strong>Methods:</strong> Fifty patients were included in this study and they were divided into two groups. In group A which included 25 patients punctal plugs were inserted and in group B (25 patients or 50 eyes) artificial tear drop was prescribed. The primary treatment outcome was the improvement in dry eye symptoms and secondary outcome was Schirmer test score, tear break up time and rose bengal staining score.</p><p class="abstract"><strong>Results:</strong> There was drastic improvement in dry eye symptoms in group A (punctal plugs) compared to group B (artificial tear group). Schirmer test score, tear break up and rose bengal staining score also improved in punctal plug group.</p><p class="abstract"><strong>Conclusions: </strong>This study has shown that punctal plug can be used as a primary treatment modality in moderate to severe dry eye as it improves greater symptomatic relief and also improves the condition of damaged ocular surface.</p>

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