Vaccine roll-out around the world

2021 ◽  
Vol 249 (3317) ◽  
pp. 9
Keyword(s):  
The World ◽  
Roll Out

scholarly journals Rapid isolation and resolution immune evasion and viral fitness across contemporary SARS-CoV-2 variants

2022 ◽  
Author(s):  
Anupriya Aggarwal ◽  
Alberto Stella ◽  
Anouschka Akerman ◽  
Gregory Walker ◽  
Vanessa Milogiannakis ◽  
...  
Keyword(s):  
Mortality Rates ◽  
Viral Fitness ◽  
Neutralising Antibodies ◽  
Viral Isolation ◽  
Rapid Isolation ◽  
The World ◽  
Developed World ◽  
Late Stages ◽  
Rapid Emergence ◽  
Roll Out

Abstract From late 2020 the world observed the rapid emergence of many distinct SARS-CoV-2 variants. At the same time, pandemic responses coalesced into significant global vaccine roll-out that have now significantly lowered Covid-19 hospital and mortality rates in the developed world. Over this period, we developed a rapid platform (R-20) for viral isolation and characterisation using primary remnant diagnostic swabs. This combined with quarantine testing and genomics surveillance, enabled the rapid isolation and characterisation of all major SARS-CoV-2 variants (all variants of concern and 6 variants of interest) globally with a 4-month period. This platform facilitated viral variant isolation and enabled rapid resolution of variant phenotype by allowing determining end point viral titers from primary nasopharyngeal swabs and through ranking of evasion of neutralising antibodies. In late 2021, when the Delta variant was dominating, Omicron rapidly emerged. Using this platform, we isolated and tested the first cases of this variant within Australia. In this setting we observed Omicron to diverge from other variants at two levels: Firstly, it ranks at the mots evasive to neutralisation antibodies compared to all VOCs and major VUIs. Secondly, it no longer engages TMPRSS2 during the late stages of fusion.

East and West will divide over new Bosnian viceroy

2021 ◽  
Keyword(s):  
World Bank ◽  
Common Interest ◽  
Content Type ◽  
The World Bank ◽  
The World ◽  
East And West ◽  
Dayton Agreement ◽  
Negative Behaviour ◽  
Roll Out ◽  
The Eu

Significance The summit’s avowed aim was to renew the EU-US ‘Transatlantic partnership’, including committing to upholding the international rules-based order built around the UN. It called for cooperation with Russia in areas of common interest despite its repeated “negative behaviour”. Such strains include Russia’s opposition to appointing a new high representative for Bosnia. Impacts Vucic’s call for regular reports from the high representative recognises his legitimacy while asserting Serbian interest in BiH. Croatian President Zoran Milanovic’s support for the 1995 Dayton agreement weakens outside backing for Bosnian Croat separatism. The World Bank has left its growth forecast for BiH unchanged from January, provided vaccine roll-out accelerates.

scholarly journals Challenges in Vaccine Acceptance– A Framework & Toolkit for the COVID -19 Battle

2021 ◽  
Vol 33 (2) ◽  
pp. 239-241
Author(s):  
Thanjavur S Ravikumar ◽  
Rakesh Kakkar ◽  
Vinoth Kumar Kalidoss
Keyword(s):  
Public Health ◽  
Moving Average ◽  
Relative Performance ◽  
Reverse Direction ◽  
World Population ◽  
Vaccine Acceptance ◽  
The Poor ◽  
The World ◽  
Roll Out

During the first wave of this COVID-19 pandemic, India’s performance was relatively superior among the countries that had their first cases in January 2020. We grouped these countries as ‘January Cohort’ and analysed their relative performance (IJCH, April 2020), supporting India’s management. Fast forward to the present, India’s performance is woefully lacking, accounting for 30% of daily cases and 31% daily deaths with 18% of the world population [Worldometer Coronavirus database, June1,2021). On this same day, 50% of the countries worldwide (110 of 222) reported no deaths and 25% (57) without any daily new cases. Thus, we have faltered with a series of public health missteps despite a good start. The latest and the most remarkable failure of India is the vaccination, despite being the world’s foremost producer. Many of the poor performers initially in the January Cohort, such as UK and USA, focused on ‘vaccinating their way out of the pandemic’ since the roll out of vaccines in December2020. The results are in display starting February 2021- to date, with cases/ deaths on decline in these countries, while India is in a reverse direction. On June 1st, UK reported no COVID-19 deaths and USA had about 31% decline of 14-day moving average.

scholarly journals Trends of industry-leading biotechnology stocks during COVID-19

2021 ◽  
Vol 10 (3) ◽  
Author(s):  
Navia Zhang ◽  
Meredith Haskins
Keyword(s):  
Stock Prices ◽  
Stock Price ◽  
Blood Clotting ◽  
New Technologies ◽  
Share Prices ◽  
The World ◽  
Biotechnology Companies ◽  
Pandemic Vaccine ◽  
Biotechnology Sector ◽  
Roll Out

The 2019-nCoV coronavirus has significantly impacted the macroeconomic outlook for countries across the world. The biotechnology sector experienced a relatively positive stock price outlook, which corroborates the trends exhibited by biotechnology stocks in previous pandemics such as SARS (2003) and AH1N1 (2009). During the COVID-19 pandemic, vaccine roll-out rates have been more efficient than in any other pandemic, as companies today are more experienced in combating the time constraint to create vaccines. Gilead Sciences Inc. saw its shares rise 18% after developing the first FDA-approved COVID-19 vaccine, 'remdesivir'. In contrast, AstraZeneca's shares fell 2.28% in 2021 after its vaccine underwent investigations into blood-clotting side effects and subsequent suspension from several countries. Companies developing mRNA vaccines like Moderna, BioNTech, and Pfizer witnessed surges in share prices ranging from 10% to 20%. Many newer biotech companies such as Genexie, Sanovi, OnoSec, and Vaxart have also developed vaccines for COVID-19. Share prices are more volatile for these less established companies. This paper observes how developing new technologies, staging clinical trials, obtaining FDA approvals, gaining publicity, and several other complex factors have profound impacts on the stock prices of these biotechnology companies.

Central America’s vaccine efforts face mixed prospects

2021 ◽  
Keyword(s):  
United States ◽  
Central America ◽  
The United States ◽  
Central American ◽  
World Health ◽  
Business Travel ◽  
Content Type ◽  
The World ◽  
Health Organization ◽  
Roll Out

Significance Elsewhere in the region, only Panama has so far received a first vaccine shipment, suggesting roll-outs initially will be patchy. Central American governments are sourcing their vaccines either through direct purchases from manufacturers or through programmes run by the World Health Organization (WHO). Impacts A black market is likely to emerge both for vaccines and vaccination certificates. Poorer countries will receive more vaccine support once roll-outs have advanced in wealthier countries globally, but this may take time. Vaccine roll-out in the United States will benefit Central America in terms of tourism, business travel and investment recovery.

scholarly journals What can we learn from Israel’s rapid roll out of COVID 19 vaccination?

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Martin McKee ◽  
Selina Rajan
Keyword(s):  
Public Health ◽  
Health Workers ◽  
Vaccination Program ◽  
The Political ◽  
Young Population ◽  
Disadvantaged Groups ◽  
Public Health Infrastructure ◽  
Health Infrastructure ◽  
The World ◽  
Roll Out

AbstractIsrael has led the world in rolling out its COVID-19 vaccination program. This experience provides lessons that others can learn from. It is, however, necessary to consider some national specificities, including the small size of the country, its young population, and the political imperative to drive this program forward. Israel also has a number of other advantages, including a strong public health infrastructure. The lessons that can be learnt include the importance of coordinating delivery mechanisms with the inevitable prioritisation of groups within the population, timely deployment of a skilled cadre of health workers, a recognition that not everyone in the population shares in the benefits of digital connectedness, the need to reach out to disadvantaged groups, based on an understanding of the barriers that they face, and the importance of placing COVID-19 vaccination within a comprehensive response to the pandemic.

scholarly journals Transfers and Implementations of a Swedish Manual Work Program: Sloyd and Entrepreneurial Power

2018 ◽  
Vol 40 (1) ◽  
pp. 29-48
Author(s):  
Martin Lawn
Keyword(s):  
19Th Century ◽  
Manual Work ◽  
Work Program ◽  
The Us ◽  
The World ◽  
The Uk ◽  
The 19Th Century ◽  
Roll Out

Sloyd, a Swedish handwork programme for schools, beginning in the late years of the 19th century, was influential in Sweden but almost immediately it began to influence teachers and educators from other countries. This influence is explored in this paper. Using transnational historiography, the sites of influence, and the flow of people and texts, is explored. The focus here is on the circulations of ideas and practices between states, and in particular, between Sweden, the US, the UK and India, and the particular ways in which this flow and embedding of Sloyd occurred.The paper is about Sloyd and about the conditions underlying its influence in other countries, broadly from the 1890s to the 1930s, although its effects continued to roll out across the world after this period.

Sustainability in the Context of Event Management

2021 ◽  
Author(s):  
Ljubomir Janjusevic ◽  
Mohamed Salama
Keyword(s):  
Event Management ◽  
The World ◽  
Planning Tools ◽  
Key Factor ◽  
Global Tourism ◽  
The Impact ◽  
Near Future ◽  
Roll Out ◽  
Factor Input

Enormous numbers of different type of events are taking place all around the world, impacting the environment and consuming a wider range of resources. For most businesses and organisations, the impact their activities have on the environment and sustainability is becoming a key factor input when planning and organizing events of all kinds. Festivals and events, in general, are important components of the tour- ism industry. With worldwide growth of festivals and events and global tourism set to reach 1.6 billion arrivals by in the near future, it is important to develop planning tools to facilitate the roll out of sustainably man- aged events. Festivals and events create significant impacts both positive and negative on the environment, society, and the economy. Therefore, sustainable event management is gaining attraction and is, in many cases, demanded as it provides an opportunity to manage these impacts while improving the quality of events.

Revisiting the Use of Cash Rewards in the Workplace: Evidence of Their Differential Impact on Employees’ Experiences in Three Samples Using Self-Determination Theory

2019 ◽  
Vol 51 (3) ◽  
pp. 92-111
Author(s):  
Anaïs Thibault Landry ◽  
Jacques Forest ◽  
Drea Zigarmi
Keyword(s):  
Self Determination Theory ◽  
Psychological Needs ◽  
Self Determination ◽  
Practical Relevance ◽  
Differential Impact ◽  
Three Samples ◽  
The World ◽  
Roll Out

Using self-determination theory, this research sheds light on the role of different subjective, or functional, meanings of cash rewards on employees’ functioning. Based on three samples of workers from across the world in a variety of industries, the current research provides empirical evidence that cash rewards perceived as having an informative meaning positively contribute to their psychological needs, which leads to better functioning, whereas cash rewards perceived as having a controlling meaning negatively contributed to their psychological needs, which is then associated with suboptimal functioning. These findings highlight the theoretical and practical relevance of considering employees’ perceptions to understand the influence of cash reward programs on their commitment, quality of motivation and behaviors in the workplace as well as to better design these programs, including their roll out strategies, if organizations set those in place to drive healthier forms of motivation and commitment.

scholarly journals Strategies for COVID-19 vaccination under a shortage scenario: a geo-stochastic modelling approach

2021 ◽  
Author(s):  
N. L. Barreiro ◽  
C. I. Ventura ◽  
T. Govezensky ◽  
M. Núñez ◽  
P. G. Bolcatto ◽  
...  
Keyword(s):  
Stochastic Model ◽  
Stochastic Modelling ◽  
World Health ◽  
Open Problems ◽  
Vaccination Strategies ◽  
The World ◽  
Health Organization ◽  
Vaccination Campaigns ◽  
Roll Out ◽  
Modelling Approach

ABSTRACTIn a world being hit by waves of COVID-19, vaccination is a light on the horizon. However, the roll-out of vaccination strategies and their influence on the pandemic are still open problems. In order to compare the effect of various strategies proposed by the World Health Organization and other authorities, a previously developed SEIRS stochastic model of geographical spreading of the virus is extended by adding a compartment for vaccinated people. The parameters of the model were fitted to describe the pandemic evolution in Argentina, Mexico and Spain to analyze the effect of the proposed vaccination strategies. The mobility parameters allow to simulate different social behaviors (e.g. lock-down interventions). Schemes in which vaccines are applied homogeneously in all the country, or limited to the most densely-populated areas, are simulated and compared. The second strategy is found to be more effective. Moreover, under the current global shortage of vaccines, it should be remarked that immunization is enhanced when mobility is reduced. Additionally, repetition of vaccination campaigns should be timed considering the immunity lapse of the vaccinated (and recovered) people. Finally, the model is extended to include the effect of isolation of detected positive cases, shown to be important to reduce infections.

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