Australine and related alkaloids: easy structural confirmation by 13C NMR spectral data and biological activities

The present work is a review of the literature of clerodane diterpenes from Croton species. It contains a compilation of 13C NMR data of 83 of these diterpenoids and their biological activities. This review covers a period from 1969 to October 2005 and 224 references are cited.

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Heliannuol: Distribution, Biological Activities, 1H and 13C-NMR Spectral Data

Mini-Reviews in Organic Chemistry ◽

10.2174/1570193x16666190405102658 ◽

2020 ◽

Vol 17 (3) ◽

pp. 309-322 ◽

Cited By ~ 1

Author(s):

Carlos Magno Rocha Ribeiro ◽

Thiago Silva Galvão de Souza ◽

Karinne Canevalli de Almeida ◽

Karen Danielle Borba Dutra ◽

Alessandra Leda Valverde

Keyword(s):

Biological Activity ◽

Helianthus Annuus ◽

Spectral Data ◽

13C Nmr ◽

Biological Activities ◽

Rapid Identification ◽

Routine Analysis ◽

Important Class ◽

1H And 13C Nmr ◽

Crude Extracts

: Heliannuols are an important class of compounds isolated from Helianthus annuus, a common sunflower, with allelopathic properties. Interestingly, two of these fourteen compounds have been isolated from a gorgonian, Pseudopterogorgia rigida. This review compiles data on the isolation and biological activity of heliannuols described in the literature and briefly reports the papers describing their syntheses. This review could stimulate research into other natural species and syntheses. Further, it describes the 1H and 13C-NMR spectral data described in the literature for the 14 heliannuols already isolated and correlates them with their respective structures. Therefore, we believe that these searchable data enable a rapid identification in routine analysis of the crude extracts of sunflowers or gorgonians.

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Synthesis and Spectral Characterization of New S-Alkylated 1,2,4-Triazoles as Potential Biological Agents

Revista de Chimie ◽

10.37358/rc.17.10.5900 ◽

2017 ◽

Vol 68 (10) ◽

pp. 2436-2439

Author(s):

Stefania Felicia Barbuceanu ◽

Laura Ileana Socea ◽

Constantin Draghici ◽

Elena Mihaela Pahontu ◽

Theodora Venera Apostol ◽

...

Keyword(s):

Mass Spectrometry ◽

Spectral Data ◽

1H Nmr ◽

Elemental Analysis ◽

13C Nmr ◽

Ethyl Bromide ◽

Spectral Characterization ◽

Basic Medium ◽

Phenacyl Bromide

In the work we presented the behavior of 5-(4-(4-X-phenylsulfonyl)phenyl)-4-(n-propyl)-2H-1,2,4-triazole-3(4H)-thiones (X= Cl or Br) with some alkylation agents. Thus, new S-alkylated 1,2,4-triazole derivatives were synthesized by reaction of the corresponding 1,2,4-triazole-3-thione derivatives with different �-halogenated compounds (ethyl bromide, ethyl chloroacetate or phenacyl bromide), in basic medium. The structures of synthesized compounds were elucidated by spectral data (1H-NMR, 13C-NMR, mass spectrometry) and elemental analysis.

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8-Acyl-7-phenylbicyclo[2.2.2]-2,6-diones by rearrangement of 3-acyloxy-5-(2-phenylethenyl)-2-cyclohexen-1-ones. 1H and 13C NMR spectral evidence of their structure

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc19901208 ◽

1990 ◽

Vol 55 (5) ◽

pp. 1208-1215 ◽

Cited By ~ 1

Author(s):

Pavel Hrnčiar ◽

Tibor Liptay ◽

Ján Šraga

Keyword(s):

Double Bond ◽

Spectral Data ◽

13C Nmr ◽

1H And 13C Nmr ◽

Spectral Evidence ◽

C Nmr

3-Acyloxy-5-(2-phenylethenyl)-2-cyclohexen-1-ones II were prepared by O-acylation of 5-(2-phenylethenyl)-1,3-cycloxanedione (I). Treatment of II with AlCl3 resulted in rearrangement of the acyl group to the double bond of the phenylethenyl grouping followed by cyclization to 8-acyl-7-phenylbicyclo[2.2.2]octane-2,6-diones III. Their structure was evidenced by analysis of the 1H and 13C NMR spectral data.

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Green Synthetic Protocol for (E)-1-Aryl-3-(2-morpholinoquinolin- 3-yl)prop-2-en-1-ones and Their Antimicrobial Activity

Asian Journal of Chemistry ◽

10.14233/ajchem.2019.21968 ◽

2019 ◽

Vol 31 (9) ◽

pp. 1895-1898

Author(s):

Relangi Siva Subrahmanyam ◽

Venkateswara Rao Anna

Keyword(s):

Antimicrobial Activity ◽

Spectral Data ◽

1H Nmr ◽

13C Nmr ◽

Mass Spectral Data ◽

In Vitro Antimicrobial Activity ◽

Mass Spectral ◽

Fungal Organisms

We report here an easy, efficient and green synthetic protocol for the (E)-1-aryl-3-(2-morpholinoquinolin-3-yl)prop-2-en-1-ones by the Claisen-Schmidt condensation of 2-morpholinoquinoline-3-carbaldehyde and different substituted acetophenones by using 1-butyl-3-methylimidazolium tetrafluoroborate (Bmim)BF4. The compounds were characterized by using 1H NMR, 13C NMR and mass spectral data and screened there in vitro antimicrobial activity against different bacterial and fungal organisms.

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Natural products isolated from Casimiroa

Open Chemistry ◽

10.1515/chem-2020-0128 ◽

2020 ◽

Vol 18 (1) ◽

pp. 778-797

Author(s):

Khun Nay Win Tun ◽

Nanik Siti Aminah ◽

Alfinda Novi Kristanti ◽

Hnin Thanda Aung ◽

Yoshiaki Takaya

Keyword(s):

Natural Products ◽

Spectral Data ◽

Aromatic Compounds ◽

Biological Activities ◽

Chemical Constituents ◽

Quinoline Alkaloids

AbstractAbout 140 genera and more than 1,600 species belong to the Rutaceae family. They grow in temperate and tropical zones on both hemispheres, as trees, shrubs, and herbs. Casimiroa is one of the genera constituting 13 species, most of which are found in tropical and subtropical regions. Many chemical constituents have been derived from this genus, including quinoline alkaloids, flavonoids, coumarins, and N-benzoyltyramide derivatives. This article reviews different studies carried out on aromatic compounds of genus Casimiroa; their biological activities; the different skeletons of coumarins, alkaloids, flavonoids, and others; and their characteristic NMR spectral data.

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N-(2-(1H-Indol-3-yl)ethyl)-2-(6-methoxynaphthalen-2-yl)propanamide

Molbank ◽

10.3390/m1187 ◽

2021 ◽

Vol 2021 (1) ◽

pp. M1187

Author(s):

Stanimir Manolov ◽

Iliyan Ivanov ◽

Dimitar Bojilov

Keyword(s):

Spectral Data ◽

13C Nmr ◽

Title Compound ◽

High Yield ◽

Mass Spectral Data ◽

Mass Spectral

The title compound was obtained in high yield in the reaction between tryptamine and naproxen. The newly synthesized naproxen derivative was fully analyzed and characterized via 1H, 13C-NMR, UV, IR, and mass spectral data.

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(1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-Methyl-1H-tetrazol-5-yl)thio)Cyclopent-2-en-1-ol

Molbank ◽

10.3390/m1199 ◽

2021 ◽

Vol 2021 (2) ◽

pp. M1199

Author(s):

Milene A. G. Fortunato ◽

Filipa Siopa ◽

Carlos A. M. Afonso

Keyword(s):

Spectral Data ◽

13C Nmr ◽

Ring Opening ◽

Environmentally Friendly ◽

Mass Spectral Data ◽

Mass Spectral ◽

Excellent Yield ◽

Ring Opening Reaction ◽

Nucleophilic Ring Opening

Using environmentally friendly conditions, the nucleophilic ring-opening reaction of 6-azabicyclo[3.1.0]hex-3-en-2-ol with 1-methyl-1H-tetrazole-5-thiol provided a novel thiol-incorporated aminocyclopentitol, (1R,4S,5S)-5-((3-hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol, in excellent yield (95%). The newly synthesized compound was analyzed and characterized via 1H, 13C-NMR, HSQC, and mass spectral data.

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Some complexes of N-aryl furfural nitrones with Co (II), Ni (II), Cu (II), Zn (II) and Cd (II) chlorides

International Journal of Advanced Chemistry ◽

10.14419/ijac.v4i1.6086 ◽

2016 ◽

Vol 4 (1) ◽

pp. 10

Author(s):

Amer A. Taqa

Keyword(s):

Spectral Data ◽

General Formula ◽

Elemental Analysis ◽

13C Nmr ◽

High Frequency ◽

Metal Ion ◽

Uv Spectroscopy ◽

Active Atom ◽

Tetrahedral Complexes

Some new metal(II) dichloride complexes with the ligands substituted nitrones of the general formula [ML2Cl2], where M= Co(II), Ni(II), Cu(II), Zn(II) and Cd(II), L=OCH=CHCH=C-CH=N(O)C6H4X (X=H,p-CH3,CH3O,CH3CO,F,Cl,and Br) have been prepared and characterized by elemental analysis, IR,1H,13C NMR and Vis/Uv spectroscopy. The IR spectral data showed that the nitrone ligands coordinated with the metal ion through the most active atom of the N-oxide to give square planner coordinate (Cu,Ni,) complexes and (Zn,Cd,Co) tetrahedral complexes. No correlation was observed between the N-O vibrations stretching high frequency ν (N-O) of the complexes and the Hammet (σ) constants.

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Synthesis of New Furothiazolo Pyrimido Quinazolinones from Visnagenone or Khellinone and Antimicrobial Activity

Molecules ◽

10.3390/molecules23112793 ◽

2018 ◽

Vol 23 (11) ◽

pp. 2793 ◽

Cited By ~ 7

Author(s):

Ameen Abu-Hashem

Keyword(s):

Antimicrobial Activity ◽

Growth Inhibition ◽

Spectral Data ◽

Elemental Analysis ◽

13C Nmr ◽

Heterocyclic Compounds ◽

Gram Negative Bacteria ◽

Gram Negative ◽

Bacteria And Fungi ◽

New Compounds

Substituted-6-methyl-1-thioxo-1,2-dihydro-3H-furo[3,2-g]pyrimido[1,6-a]quinazolin-3-ones (5a,b) were synthesized from condensation of visnagenone (2a) or khellinone (2b) with 6-amino-thiouracil (3) in dimethylformamide or refluxing of (4a) or (4b) in dimethylformamide. Hence, compounds (5a,b) were used as the starting materials for preparing many new heterocyclic compounds such as; furo[3,2-g]pyrimido[1,6-a]quinazoline (6a,b), furo[3,2-g]thiazolo[2′,3′:2,3]pyrimido[1,6-a]quinazolinone (7a,b), substituted-benzylidene-furo[3,2-g]thiazolo[2′,3′:2,3]pyrimido[1,6-a]quinazoline-3,5-dione (8a–f), 3-oxo-furo[3,2-g]pyrimido[1,6-a]quinazoline-pentane-2,4-dione (9a,b), 1-(pyrazole)-furo[3,2-g]pyrimido[1,6-a]quinazolinone (10a,b), 2-(oxo or thioxo)-pyrimidine-furo[3,2-g]pyrimido[1,6-a]quinazolinone (11a–d), 1-(methylthio)-furo[3,2-g]pyrimido[1,6-a]quinazolinone (12a,b), 1-(methyl-sulfonyl)-furo[3,2-g]pyrimido[1,6-a]quinazolinone (13a,b) and 6-methyl-1-((piperazine) or morpholino)-3H-furo[3,2-g]pyrimido[1,6-a]quinazolin-3-one (14a–d). The structures of the prepared compounds were elucidated on the basis of spectral data (IR, 1H-NMR, 13C-NMR, MS) and elemental analysis. Antimicrobial activity was evaluated for the synthesized compounds against Gram-positive, Gram-negative bacteria and fungi. The new compounds, furothiazolo pyrimido quinazolines 8a–f and 11a–d displayed results excellent for growth inhibition of bacteria and fungi.

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