P-230 Gender Difference of Cardiometabolic Risk and Role of Adiponectin in Visceral Fat Obesity with Normal Waist Circumference

Abstract Background Cardiometabolic risk is increased in severe mental disorders (SMDs), and there appears to be a relationship between childhood trauma and cardiometabolic risk, possibly related to adverse health behavior. The current study examined the association between childhood trauma and serum lipids and adiposity in SMDs and the potential mediating role of cognitive and personality characteristics. Methods Participants with schizophrenia and bipolar spectrum disorders (N = 819) were included, cardiometabolic risk factors (serum lipids, body mass index, and waist circumference) were measured, and history of childhood trauma was assessed by the Childhood Trauma Questionnaire. Cognitive and personality characteristics were available in subsamples, with assessments of cognitive control, impulsiveness, self-esteem, and affective lability. Linear regressions and mediation analyses with Hayes’ PROCESS were performed, adjusting for age, sex, antipsychotic agent propensity of metabolic side-effect, and diagnostic group. Results Experience of three or more subtypes of childhood trauma was positively associated with waist circumference in patients with SMDs (p = 0.014). There were no other significant associations between trauma variables and lipid or adiposity measures in the total sample. Cognitive control was a significant mediator between experience of one or two subtypes of childhood trauma and waist circumference. Conclusions The results indicate childhood trauma as a predisposing factor for increased waist circumference in individuals with SMDs. Poorer cognitive control, suggestive of adverse health behavior, might be a mediating factor of the association, and the findings indicate the potential importance of increased focus on these factors in prevention and treatment regimens targeting cardiometabolic health.

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Superior Role of Waist Circumference to Body-Mass Index in the Prediction of Cardiometabolic Risk in Dyslipidemic Patients

Physiological Research ◽

10.33549/physiolres.934176 ◽

2019 ◽

pp. 931-938

Author(s):

Ľ. Cibičková ◽

K. Langová ◽

H. Vaverková ◽

J. Lukeš ◽

N. Cibiček

Keyword(s):

Insulin Resistance ◽

Metabolic Syndrome ◽

Body Mass Index ◽

Waist Circumference ◽

Lipid Profile ◽

Body Mass ◽

Cardiometabolic Risk ◽

Predictive Values ◽

High Bmi

Coronary risk evaluation by conventional factors (age, gender, smoking, blood pressure and cholesterol) may further be specified by facets of the metabolic syndrome, namely insulin resistance, hypertriglyceridemia and obesity. Although obesity is usually defined as elevated body mass index (BMI), recent data indicate a superior role of waist circumference or hypertri-glyceridemic waist (HTGW) over BMI in the assessment of cardiometabolic risk. In dyslipidemic patients, the specific contributions of risky waist, HTGW or BMI have not been evaluated as yet. 686 dyslipidemic subjects (322 males and 364 females) were enrolled into a cross-sectional study. In each subject basic antropometry (i.e. waist circumference, HTGW, BMI) and laboratory parameters of lipid profile and insulin resistance were determined. Cardiometabolic risk was given by fulfilling the criteria (harmonized definition) of metabolic syndrome. The significance of risky waist, HTGW and BMI were assessed by comparing the respective predictive values for the presence of metabolic syndrome. Dyslipidemic patients with risky waist, HTGW or high BMI have a more atherogenic lipid profile and higher insulin resistance compared to those without risky waist, HTGW or high BMI. Risky waist is stronger predictor of metabolic syndrome (PPV 66 %, NPV 90 %) and thus posesa greater cardiometabolic risk than higher BMI per se does (PPV 42 %, NPV 97 %). The contribution of triglycerides (i.e. HTGW) to these predictive values is marginal (PPV 66 %, NPV 92 %). The present results highlight the superior role of waist circumference as a screening tool over BMI for the evaluation of cardiometabolic risk in dyslipidemic subjects. HTGW brings little additional benefit in risk stratification. Lower BMI proved to be optimal for identifying the subjects with inferior risk.

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Alteration of the growth hormone axis, visceral fat dysfunction, and early cardiometabolic risk in adults: the role of the visceral adiposity index

Endocrine ◽

10.1007/s12020-014-0471-z ◽

2014 ◽

Vol 49 (2) ◽

pp. 492-502 ◽

Cited By ~ 8

Author(s):

Carolina Di Somma ◽

Alessandro Ciresi ◽

Marco C. Amato ◽

Silvia Savastano ◽

Maria Cristina Savanelli ◽

...

Keyword(s):

Growth Hormone ◽

Visceral Fat ◽

Cardiometabolic Risk ◽

Visceral Adiposity ◽

Visceral Adiposity Index ◽

Adiposity Index

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1962-P: Role of Transcription Factor TCF21 in Adipocyte Progenitor Cells of Visceral Fat

Diabetes ◽

10.2337/db20-1962-p ◽

2020 ◽

Vol 69 (Supplement 1) ◽

pp. 1962-P

Author(s):

TAKUYA MINAMIZUKA ◽

YOSHIRO MAEZAWA ◽

HARUHIDE UDAGAWA ◽

YUSUKE BABA ◽

MASAYA KOSHIZAKA ◽

...

Keyword(s):

Transcription Factor ◽

Progenitor Cells ◽

Visceral Fat

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Combination of sleep duration, TV time and body mass index is associated with cardiometabolic risk moderated by age in youth

Journal of Pediatric Endocrinology and Metabolism ◽

10.1515/jpem-2020-0399 ◽

2020 ◽

Vol 0 (0) ◽

Author(s):

Ana P. Sehn ◽

Anelise R. Gaya ◽

Caroline Brand ◽

Arieli F. Dias ◽

Roya Kelishadi ◽

...

Keyword(s):

Body Mass Index ◽

Risk Factor ◽

Sleep Duration ◽

Body Mass ◽

Cardiometabolic Risk ◽

High Systolic Blood Pressure ◽

Television Time ◽

The Relationship ◽

Moderating Role

AbstractObjectivesThe combination of sleep duration, television (TV) time and body mass index (BMI) may be related to the alteration of cardiometabolic risk. However, there are few studies that use these variables grouped, and showing the moderating role of age. This study aimed to verify if the combination of sleep duration, TV time and BMI is associated with cardiometabolic risk and the moderating role of age in this relationship in youth.MethodsCross-sectional study conducted with 1411 adolescents (611 male), aged 10–17 years. Sleep duration, TV time and BMI were assessed and grouped into eight categories. Cardiometabolic risk was assessed by a continuous metabolic risk score, including the following variables: low HDL-cholesterol, elevated triglycerides, dysglycemia, high systolic blood pressure, high waist circumference and low cardiorespiratory fitness. Generalized linear models were used to test moderation of age in the relationship between the eight categories of sleep duration/television time/BMI with cardiometabolic risk.ResultsCardiometabolic risk factor showed association with all overweight or obesity independent of sleep time and TV time. Age moderated the relationship between sleep duration/television time/BMI with cardiometabolic risk. This association was stronger in younger adolescents (11 and 13 years), indicating that individuals with inadequate sleep, prolonged TV time and overweight/obesity present higher cardiometabolic risk values when compared to 15-year-old adolescents.ConclusionOverweight/obesity, independently of sleep duration and TV time, is the main risk factor for cardiometabolic disorders in adolescence. When moderated by age, younger adolescents that presented the combination of risk factors had higher cardiometabolic risk.

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Associations of Body Mass Index, Visceral Fat Area, Waist Circumference, and Waist-to-Hip Ratio with Cognitive Function in Western China: Results from WCHAT Study

The journal of nutrition health & aging ◽

10.1007/s12603-021-1642-2 ◽

2021 ◽

Author(s):

X. Liu ◽

X. Chen ◽

L. Hou ◽

X. Xia ◽

F. Hu ◽

...

Keyword(s):

Body Mass Index ◽

Cognitive Function ◽

Waist Circumference ◽

Body Mass ◽

Visceral Fat ◽

Western China ◽

Visceral Fat Area ◽

Waist To Hip Ratio

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Examining the Role of Power-Control Theory and Self-Control to Account for Computer Hacking

Crime & Delinquency ◽

10.1177/0011128720981892 ◽

2020 ◽

pp. 001112872098189

Author(s):

Thomas J. Holt ◽

Kevin F. Steinmetz

Keyword(s):

Gender Difference ◽

Control Theory ◽

Power Control ◽

Gender Disparity ◽

Criminological Theory ◽

Self Control ◽

Self Report ◽

Computer Hacking ◽

Using Data

Criminological inquiry consistently identifies a gender difference in offending rates, which are also evident among certain forms of cybercrime. The gender difference in cybercrime offending is particularly large within computer hacking, though few have specifically addressed this issue through applications of criminological theory. The current study attempted to account for the gender disparity in hacking through a test of power-control theory, which considers the role of class and family structure. This analysis also incorporated an extension of power-control theory through the influence of low self-control. Using data from the Second International Self-Report of Delinquency study (ISRD-2), logistic regression analyses were estimated, producing partial support for both theories to account for hacking. Implications for theory and research were explored in detail.

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Mental Health Among Employed Family Caregivers: A Gender-Based Analysis on the Role of Workplace Support

Innovation in Aging ◽

10.1093/geroni/igaa057.242 ◽

2020 ◽

Vol 4 (Supplement_1) ◽

pp. 74-74

Author(s):

Lun Li ◽

Yeonjung Lee ◽

Daniel W L Lai

Keyword(s):

Mental Health ◽

Gender Difference ◽

Family Caregivers ◽

Moderated Mediation ◽

Moderating Effect ◽

Workplace Support ◽

Employment Adjustment ◽

Different Types ◽

The Impact

Abstract Compared to men, women undertake more family caregiving responsibilities, and thus take more toll in health and wellbeing when they are employed. The current study examined the gender difference in mental health among employed family caregivers, focusing on the role of workplace support in balancing work and caregiving roles. Guided by the social role theory and the moderated-mediation model of employment adjustment and mental health, we analyzed a nationally representative data from the 2012 Canada General Social Survey - Caregiving and Care Receiving with a sample of 2,426 participants selected. Moderated-mediation analysis based on the SPSS macro PROCESS 3.3 was used. Women employed family caregivers are more likely to undertake higher intensive caregiving, make more employment adjustment, and further report worse mental health status than their men counterparts. Gender difference was apparent in regards to the workplace support. For women, the moderating effect of workplace support is significant only when there are at least 5 different types of workplace support available at their workplaces, while for men, the moderating effect is significant when there are at least 2-3 different types of workplace support available. Women employed family caregivers experience worse mental health when employment adjustment is needed for their care responsibility. Findings have implications for providing workplace support for family caregivers given that women benefit less from workplace support compared to men. Further study is needed to explore the impact of various types of workplace support for women employed family caregivers, and to provide tailored support to them.

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