A Year in the Life of a Contaminated Heater-Cooler Unit With Mycobacterium chimaera?

2017 ◽  
Vol 38 (06) ◽  
pp. 705-711 ◽  
Author(s):  
Mark I. Garvey ◽  
Craig W. Bradley ◽  
Jimmy Walker
Keyword(s):  
United Kingdom ◽  
Water Samples ◽  
Membrane Filtration ◽  
Microbial Load ◽  
Water Sampling ◽  
University Hospitals ◽  
The Past ◽  
The United Kingdom ◽  
Wide Range ◽  
Number Of Microorganisms

OBJECTIVE Heater-cooler units (HCUs) have been shown to be a source of Mycobacterium chimaera infections. For the past year, weekly water samples have been taken from HCUs used at University Hospitals Birmingham (UHB) NHS Foundation Trust. We report the microbial contamination of the HCUs over a year detailing the decontamination regimes applied at UHB to reduce the microbial load. DESIGN Observational study SETTING UHB is a tertiary referral teaching hospital in Birmingham, United Kingdom, that provides clinical services to nearly 1 million patients every year. The UHB Cardiac department is one of the largest in the United Kingdom and provides treatment for adult patients with a wide range of cardiac diseases. METHODS Water samples taken from HCUs used at UHB for cardiopulmonary bypass surgery were sampled over a year to determine the number of microorganisms by membrane filtration. Various decontamination processes were employed throughout the year. RESULTS Varying total viable counts containing a wide variety of microorganisms were obtained from water inside the HCUs. No M. chimaera were isolated after replacement of the HCU internal tubing. Stringent decontamination regimes resulted in degradation of the HCUs and increased TVCs after several months. CONCLUSION More work is required to ensure effective decontamination processes to reduce the microbial load within the HCUs. Our studies indicate that weekly water sampling for TVC will be required indefinitely to monitor the water quality in these units as well as regular replacement of the tubing to control the build-up of biofilm. Infect Control Hosp Epidemiol 2017;38:705–711

An Improved Membrane Filtration Method for Enumeration of Faecal Coliforms and E. Coli by a Fluorogenic β-Glucuronidase Assay

1993 ◽  
Vol 27 (3-4) ◽  
pp. 267-270 ◽  
Author(s):  
M. T. Augoustinos ◽  
N. A. Grabow ◽  
B. Genthe ◽  
R. Kfir
Keyword(s):  
Escherichia Coli ◽  
Water Samples ◽  
Membrane Filtration ◽  
Faecal Coliforms ◽  
Environmental Waters ◽  
Filtration Method ◽  
E Coli ◽  
Wide Range ◽  
Pure Cultures ◽  
Glucuronidase Assay

A fluorogenic β-glucuronidase assay comprising membrane filtration followed by selective enumeration on m-FC agar at 44.5°C and further confirmation using tlie 4-metliylumbelliferyl-β-D-glucuronide (MUG) containing medium was evaluated for the detection of Escherichia coli in water. A total of 200 typical blue and non-typical blue colonies were isolated from sea and fresh water samples using initial selective enumeration on m-FC agar. Pure cultures of the selected colonies were further tested using the MUG assay and identified using the API 20E method. Of the colonies tested which were shown to be positive using the MUG assay 99.4% were Escherichia coli. The results of this study indicate the combination of the m-FC method followed by the MUG assay to be highly efficient for the selection and confirmation of E. coli from a wide range of environmental waters.

scholarly journals Are public service media distinctive from the market? Interpreting the political information environments of BBC and commercial news in the United Kingdom

2021 ◽  
pp. 026732312110121
Author(s):  
Stephen Cushion
Keyword(s):  
United Kingdom ◽  
Public Service ◽  
Television News ◽  
Information Environment ◽  
Political Information ◽  
The Political ◽  
The United Kingdom ◽  
Wide Range ◽  
International Issues ◽  
Market Driven

Public service media face an existential crisis. Many governments are cutting their budgets, while questioning the role and value of public service broadcasting because many citizens now have access to a wide range of media. This raises the question – do public service media supply a distinctive and informative news service compared to market-led media? Drawing on the concept of political information environment, this study makes an intervention into debates by carrying out a comparative content analysis of news produced by UK public service broadcasters and market-driven media across television, radio and online outlets (N = 1065) and interviewing senior editors about the routine selection of news. It found that almost all BBC news and commercial public service media platforms reported more news about politics, public affairs and international issues than entirely market-driven outlets. Online BBC news reported more informative topics than market-based media, which featured more entertainment and celebrity stories. The value of public service media was demonstrated on the United Kingdom’s nightly television news bulletins, which shone a light on the world not often reported, especially BBC News at Ten. Most market-driven media reported through a UK prism, excluding many countries and international issues. Overall, it is argued that the influence of public service media in the United Kingdom helps shape an information environment with informative news. The focus of the study is on UK media, but the conceptual application of intepreting a political information environment is designed to be relevant for scholars internationally. While communication studies have sought to advance more cross-national studies in recent years, this can limit how relevant studies are for debates in national political information environments. This study concludes by recommending more scholarly attention should be paid to theorising national policy dynamics that shape the political information environments of media systems within nations.

Waking Up in the Poll Booth

2009 ◽  
Vol 7 (4) ◽  
pp. 901-910
Author(s):  
Robert E. Goodin ◽  
James Mahmud Rice
Keyword(s):  
United States ◽  
United Kingdom ◽  
Panel Data ◽  
The United States ◽  
Election Campaign ◽  
Individual Level ◽  
The Past ◽  
The United Kingdom ◽  
General Elections ◽  
Waking Up

Judging from Gallup Polls in the United States, the United Kingdom, and Australia, opinion often changes during an election campaign. Come election day itself, however, opinion often reverts back nearer to where it was before the campaign began. That that happens even in Australia, where voting is compulsory and turnout is near-universal, suggests that differential turnout among those who have and have not been influenced by the campaign is not the whole story. Inspection of individual-level panel data from 1987 and 2005 British General Elections confirms that between 3 and 5 percent of voters switch voting intentions during the campaign, only to switch back toward their original intentions on election day. One explanation, we suggest, is that people become more responsible when stepping into the poll booth: when voting they reflect back on the government's whole time in office, rather than just responding (as when talking to pollsters) to the noise of the past few days' campaigning. Inspection of Gallup Polls for UK snap elections suggests that this effect is even stronger in elections that were in that sense unanticipated.

School Reform and Parental Engagement Learning in the United Kingdom

2021 ◽  
Author(s):  
Janet Goodall
Keyword(s):  
United Kingdom ◽  
School Improvement ◽  
School Reform ◽  
21St Century ◽  
Parental Engagement ◽  
Reform Movements ◽  
Early 21St Century ◽  
The United Kingdom ◽  
Wide Range ◽  
Per Se

Parental engagement in children and young people’s learning has been shown to be an important lever for school improvement and young people’s outcomes. However, parents are rarely involved in school reform movements. These reform movements are generally centered on the school rather than on improvement of learning per se. Shifting the focus away from the school and to learning as an overarching aim requires the inclusion of and partnership with parents. This is a new way of understanding school reform but has the best chance of supporting all students, including those not best served by the schooling systems in the early 21st century. The reforms here are chiefly concerned with U.K. schooling systems, but could be more widely applicable, and call on a wide range of evidence, from the United Kingdom and beyond.

A Baby at All Costs? Exploring the Use and Provision of Unproven Adjuvant Treatments in the Context of IVF

2021 ◽  
Author(s):  
Georgina L. Jones ◽  
Victoria Lang ◽  
Nicky Hudson
Keyword(s):  
Reproductive Technologies ◽  
Patient Survey ◽  
Fertility Treatment ◽  
Vitro Fertilization ◽  
The Past ◽  
The United Kingdom ◽  
Wide Range ◽  
National Patient ◽  
Psychosocial Perspective

AbstractThe year 2018 marked 40 years since the birth of Louise Brown, the first baby born as a result of pioneering in vitro fertilization (IVF) treatment. Since then, advances have seen a wide range of reproductive technologies emerge into clinical practice, including adjuvant treatments often referred to as IVF “add-ons.” However, these “optional extras” have faced growing criticism, especially when they have often come at additional financial cost to the patient and have little evidence supporting their efficacy to improve pregnancy or birth rates. Despite this, according to the latest national patient survey by the Human Fertilisation and Embryology Authority, three quarters of patients who had fertility treatment in the United Kingdom in the past two years had at least one type of treatment add-on highlighting the growing demand for these interventions. This article uses a psychosocial perspective to consider the motivations behind patient and clinician behavior along with the wider societal and economic factors that may be impacting upon the increase in the use of adjuvant treatments in fertility clinics more widely. It suggests the reasons fertility patients use unproven “optional extras” are complex, with interpersonal, psychological, and social factors intertwining to generate an increase in the use of IVF add-ons.

scholarly journals Faith in Rights: the Struggle Over Same- Sex Adoption in the United Kingdom

2011 ◽  
Vol 17 (1, 2 & 3) ◽  
pp. 2008
Author(s):  
Carl F. Stychin
Keyword(s):  
United Kingdom ◽  
Sexual Orientation ◽  
Same Sex ◽  
Labour Government ◽  
The Past ◽  
The United Kingdom

Over the past decade of Labour government in the United Kingdom (U.K.), the regulation of sexual orientation through law has frequently been explained by its supporters through a nar- rative of progress and even emancipation. The most recent junction in this journey came in 2007, with the coming into force of the Equality Act (Sexual Orientation) Regulations on 30 April 2007.1 These Regulations contain measures pro- hibiting discrimination on grounds of sexual orientation in the provision of goods, facilities and services, education, the use and disposal of premises, and the exercise of public functions.

The cereal grain trade in the United Kingdom: the problem of cereal variety

1984 ◽  
Vol 304 (1120) ◽  
pp. 395-407 ◽  
Keyword(s):  
United Kingdom ◽  
Major Constituent ◽  
Variety Identification ◽  
Starch Gel Electrophoresis ◽  
Current Frequency ◽  
Growth Environment ◽  
The United Kingdom ◽  
Cereal Grain ◽  
Wide Range ◽  
The Impact

The production of cereals in the United Kingdom has increased steadily over recent years from 12.6 million tonnes in 1964 to 21.8 million tonnes in 1982. During this period, the United Kingdom’s accession to the E.E.C. in 1973 caused a reverse in the milling industry’s policy of including only a small proportion of home-grown wheat with imported wheat in breadmaking grists. Home-grown wheat is now the major constituent of mass produced bread. Since the passing of the Plant Varieties Rights Act in 1964, plant breeders have been able to collect royalties on the sale of seed of their varieties; this led within a decade to a large number of high yielding varieties on offer to the farmer. Thus during the period of adjustment to home-grown wheat after 1973, the milling industry had to select from a wide range of varieties of different milling and baking qualities. Selection was aided by the offer of a ‘premium’ (extra payment) for wheat of the right variety. The millers’ problem then was to be able to check that the wheat received was of the variety claimed by the supplier. Investigations of the heterogeneity ofgliadins by electrophoresis had been conducted by several workers, but a refined procedure was developed that used starch gel electrophoresis that was able to distinguish most varieties of wheat grown in France and the E.E.C. Different electrophoretic patterns were obtained from individual grains of different varieties: grains of the same variety gave similar patterns irrespective of growth environment. Subsequent developments of variety identification by electrophoresis have improved the resolution and time of analysis. Use of electrophoresis to check the varietal composition of grain being supplied to a British miller revealed that contracts that specified varietal content were usually, but not always, complied with. It was found that the miller was able to seek financial reimbursement from his supplier to compensate for the poorer grade of wheat received in about one in eight deliveries from France; and in about one in seven deliveries from the British farmer. Farmers have now adjusted to growing, storing and supplying varieties separately, such that the current frequency of erroneous grain delivery is about one in 50. The impact of variety identification by electrophoresis in barley trading has been less than in wheat trading. This is partly because it is sometimes possible to verify a purchase through examination of grain morphology, and partly because the alternative electrophoretic analysis is often impractical, because of frequently large numbers of barley varieties carrying identical hordein proteins.

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