Some Remarks on the Mortality among Persons with Consumptive Family History

1894 ◽  
Vol 31 (5) ◽  
pp. 375-386
Author(s):  
Harald Westergaard

One of the most interesting questions in mortality statistics is that of hereditary influences, but very little light has hitherto been thrown on this subject. What effect will the good or bad health of the present generation have on that of the future one? In which way will nature eliminate the fatal germs of a family disposition? Will they disappear through a gradual dying out of the persons with such a disposition, or will they in the course of time grow less dangerous till at last they have lost entirely their original character? All these questions have hitherto been left almost unanswered in spite of the great scientific and economic interest attached to them.

Chelovek RU ◽  
2020 ◽  
pp. 18-53
Author(s):  
Sergei Avanesov ◽  

Abstract. The article analyzes the autobiography of the famous Russian philosopher, theologian and scientist Pavel Florensky, as well as those of his texts that retain traces of memories. According to Florensky, the personal biography is based on family history and continues in children. He addresses his own biography to his children. Memories based on diary entries are designed as a memory diary, that is, as material for future memories. The past becomes actual in autobiography, turns into a kind of present. The past, from the point of view of its realization in the present, gains meaning and significance. The au-thor is active in relation to his own past, transforming it from a collection of disparate facts into a se-quence of events. A person can only see the true meaning of such events from a great distance. Therefore, the philosopher remembers not so much the circumstances of his life as the inner impressions of the en-counter with reality. The most powerful personality-forming experiences are associated with childhood. Even the moment of birth can decisively affect the character of a person and the range of his interests. The foundations of a person's worldview are laid precisely in childhood. Florensky not only writes mem-oirs about himself, but also tries to analyze the problems of time and memory. A person is immersed in time, but he is able to move into the past through memory and into the future through faith. An autobi-ography can never be written to the end because its author lives on. However, reaching the depths of life, he is able to build his path in such a way that at the end of this path he will unite with the fullness of time, with eternity.


2021 ◽  
Vol 42 (02) ◽  
pp. 271-283
Author(s):  
Manila Gaddh ◽  
Rachel P. Rosovsky

AbstractVenous thromboembolism (VTE) is a major cause of morbidity and mortality throughout the world. Up to one half of patients who present with VTE will have an underlying thrombophilic defect. This knowledge has led to a widespread practice of testing for such defects in patients who develop VTE. However, identifying a hereditary thrombophilia by itself does not necessarily change outcomes or dictate therapy. Furthermore, family history of VTE by itself can increase an asymptomatic person's VTE risk several-fold, independent of detecting a known inherited thrombophilia. In this article, we will describe the current validated hereditary thrombophilias including their history, prevalence, and association with VTE. With a focus on evaluating both risks and benefits of testing, we will also explore the controversies of why, who, and when to test as well as discuss contemporary societal guidelines. Lastly, we will share how these tests have been integrated into clinical practice and how to best utilize them in the future.


eLife ◽  
2021 ◽  
Vol 10 ◽  
Author(s):  
Michelle F Jacobs

A new software package provides more accurate cancer risk prediction profiles and has the ability to integrate more genes and cancer types in the future.


2019 ◽  
Vol 121 (3) ◽  
pp. 1011-1017 ◽  
Author(s):  
Evan L. Matthews ◽  
Kelly N. Sebzda ◽  
Megan M. Wenner

A positive family history of hypertension (+FH) is a risk factor for the future development of hypertension. Hypertension is associated with reductions in baroreflex sensitivity (BRS). Therefore, we hypothesized that young women with a +FH [ n = 12, 22 ± 1 yr, body mass index (BMI) 21 ± 1 kg/m2, mean arterial pressure (MAP) 79 ± 1 mmHg] would have lower BRS compared with young women without a family history of hypertension (−FH) ( n = 13, 22 ± 1 yr, BMI 21 ± 1 kg/m2, MAP 77 ± 2 mmHg, all P > 0.05 between groups). Continuous measurements of muscle sympathetic nerve activity, blood pressure, and electrocardiogram derived R-R interval were recorded at rest and during a Valsalva maneuver. Both cardiovagal BRS and vascular sympathetic BRS were assessed. Resting cardiovagal BRS was reduced in the +FH women (all sequences: −FH 32.3 ± 3.7 vs. +FH 20.2 ± 2.9 ms/mmHg, P = 0.02). Cardiovagal BRS during phase IV (−FH 16.5 ± 2.7 vs. +FH 7.6 ± 1.3 ms/mmHg, P < 0.01) but not phase II (−FH 5.5 ± 0.9 vs. +FH 5.0 ± 0.8 ms/mmHg, P = 0.67) of the Valsalva maneuver was also lower in the +FH women. Vascular sympathetic BRS at rest (−FH −2.38 ± 0.7 vs. +FH −2.33 ± 0.3 bursts· min−1·mmHg−1, P = 0.58) and during the Valsalva (−FH −0.74 ± 0.23 vs. +FH −0.66 ± 0.18 bursts·15 s−1·mmHg−1, P = 0.79) were not different between groups. These data suggest that healthy young women with a positive family history of hypertension have reduced cardiovagal BRS. This may be one mechanism contributing to the increased incidence of hypertension in this population later in life. NEW & NOTEWORTHY Having a family history of hypertension increases the risk of developing future hypertension. Reductions in baroreflex function have been demonstrated in hypertension and are an important marker for future cardiovascular disease. We show that young women with a family history of hypertension have lower cardiovagal baroreflex sensitivity. This alteration in autonomic function may be one mechanism contributing to the future incidence of hypertension in this patient population.


2018 ◽  
Vol 5 (1) ◽  
pp. 70
Author(s):  
Zailani Zailani

The title of this paper is “The Writing Tradition of Muslim Scientists in the Archipelago Since The Age of Kingdom to Contemporary Period.” How significant is the development of the writing tradition among the scientist in the age of kingdom. What are the things that encourage these scientists to perform the writing activities. Then materially, which subject fields that muslim scientist are interested in. And also in the contemporary era, this is which is discussed in this paper. This paper is intended to discover the uniqueness of scientist in each age. It is also expected to explore whether or not there are similarities and differences between different times. This paper is qualitative type with the library research approach. By studying the history books of the Islamic empires in the Archipelago and the writings related to the work of Muslim scientists. This paper is the way how the present generation and also the future generation to be able to track and respect history, by studying and preserving it. Judul tulisan ini adalah “Tradisi Menulis Ilmuan Muslim Nusantara Sejak Zaman Kerajaan Hingga Masa Kontemporer”. Sudah sampai sejauh mana perkembangan tradisi menulis pada masa Kerajaan. Hal-hal apa saja yang mendorong para ilmuan tersebut untuk melakukan aktivitas di atas. Kemudian secara materi, bidang-bidang apa saja yang diminati oleh ilmuan muslim Nusantara.  Begitu juga pada masa zaman kontemporer, Ini salah satu bagian yang dikaji. Berupaya menemukan kekhasan masing –masing zaman. Juga diharapkan mampu mencari apakah ada atau tidak kesamaan dan perbedaan di antara masa yang berbeda. Tulisan ini  berjenis kualitatif, dengan pendekatan  library research.  Dengan mengkaji buku sejarah kerajaan Islam di Nusantara dan tulisan yang berhubungan dengan karya para ilmuan ilmuan muslim. Tulisan ini merupakan salah satu cara upaya generasi sekarang dan akan datang untuk dapat melacak dan menghormati sejarah, dengan mempelajari dan melestarikannya.


2021 ◽  
pp. 286-321
Author(s):  
E.V. Salnikova ◽  

The article is devoted to the recently found and restored film Algol. The Tragedy of Power (1920) by Hans Werckmeister, combining an adventurous beginning, fantasy, career history and family history. This is one of the earliest stories predicting the processes of globalization. The author examines the visual originality of the picture, which includes both expressionist scenes and out-of-style fragments, dwells in detail on some camera solutions. Analyzes the plot of the film, combining science and unscientific fiction with references to the series of novels (Rougon-Maccara by Zola, The Forsyte Saga by Galsworthy, Buddenbrooks by Thomas Mann) and the myth of Faust. Along with the development of the image of the modern urban environment and the civilization of the future, the images of nature play an important role: nature, included in the technogenic civilization, and self-sufficient nature, which helps the rural working people to survive. The image of the main character, Robert Hern, performed by the outstanding German actor Emil Jannings, is examined in detail. The author reflects on the paradoxical connection between the fantastic world of the film and some motives of Peplum.


2007 ◽  
Vol 58 (1) ◽  
pp. 136-246
Author(s):  
Ove Korsgaard

Debatforum[Forum for debate]In the Forum for debate, readers are invited to respond to issues raised, or to raise new issues relative to the field of Grundtvig studies. Items submitted, preferably in the form of an article, may be of any reasonable length and in any of the languages usually accepted by the journal. Contributions in Grundtvig-Studier 2007 are written by Ove Korsgaard and P.l Bødtker Walstad.Unfortunately, due to a mistake during the editing of Professor, dr. p.d. Ove Korsgaard’s contribution “Hvordan erindres folkehøjskolens historie?” in Grundtvig-Studier 2006, certain sections were misplaced. As this may have caused confusion to the readers, we are reprinting the contribution in its original form. The editors of Grundtvig-Studier 2006 would like to apologise for the misprint. Debatforum: Hvordan erindres folkehøjskolens historie?[Forum for debate: How do we recall the history of the Danish folk highschool?]By Ove KorsgaardIt is a well-recognised phenomenon in the process of historical recall that both deliberate manipulation and less conscious selectivity of what is remembered and what forgotten may distort the true record of events, even though the distorted record may then become the basis upon which the present generation shapes its prospect of the future. A close reexamination of the historical and constantly evolving struggle between competing ideals in the folk-highschools from Grundtvig’s day onwards reveals that unhistorical notions of pure and miscegenated educational models have established themselves. This distortion of the true history of the evolution of these schools may now be obstructing the clear-headed and pragmatic reassessment of its future that the folk-highschool movement is currently having to confront.


1965 ◽  
Vol 69 (658) ◽  
pp. 692-698
Author(s):  
A. E. Russell

We have heard that the SST project is the largest and most expensive project ever undertaken. It is fairly large and it is expensive. When making comparisons, however, it is important to remember that major developments in aviation have rarely been cheap. For some civil projects the subsidy has been indirect. For example, the present generation of successful American long range air liners, notably the Boeing 707, has succeeded to a large family of military progenitors and thereby enjoyed its massive inheritance. Even so, funds spent on the 707 development must have been substantial, for many hundreds of aircraft needed to be sold before the break-even point was reached. Those firms in the USA, lacking the advantage of a military ancestor, must have seen the prospect of profitability in the civil field, in straight competition with those better placed, as an illusive difference between two very large sums—launching expenditure and prospective income.Now, and in the future, all civil projects everywhere must fight for existence without benefit of feed-back from a related defence project.The question is whether to fight at all in this remorseless arena. Presumably nearly all at a meeting of the Royal Aeronautical Society would not agree that this country should reject the challenge.


2015 ◽  
Vol 37 (3) ◽  
pp. 102-127 ◽  
Author(s):  
Jerome de Groot

This article argues for the importance of genealogy and family history to contemporary understanding and experience of the past. Through looking at various ways that genealogy might be undertaken and imagined, the article argues that this important area needs to be further conceptualized and studied by public historians. The article looks at the implications inherent in the broad shift to global online genealogy and family history. The argument is interrogative and assertive in order to provoke debate amongst public historians about how we might investigate, theorize, and interrogate genealogy and family history further in the future.


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