scholarly journals Laboratory evaluation of gophacide as a rodenticide for use against Rattus norvegicus and Mus musculus

1975 ◽  
Vol 74 (1) ◽  
pp. 103-108 ◽  
Author(s):  
R. Redfern ◽  
J. H. Greaves ◽  
H. Tinworth

Laboratory tests were carried out to assess the efficacy of gophacide as a rodenticide against the Norway rat (Rattus norvegicus) and the house mouse (Mus musculus). Results of feeding tests with wild animals suggest that the compound would be more useful against mice than rats, and that 0.3% would be a near optimal concentration for field trials for both species.The hazards of using gophacide as a rodenticide are discussed.

1975 ◽  
Vol 74 (3) ◽  
pp. 441-448 ◽  
Author(s):  
M. R. Hadler ◽  
R. Redfern ◽  
F. P. Rowe

SUMMARYThe efficacy of difenacoum as a new anticoagulant rodenticide was evaluated by blood coagulation studies and laboratory feeding tests using warfarin-resistant and non-resistant common rats (Rattus norvegicus), ship rats (R. rattus) and house mice (Mus musculus). Prothrombin assays indicated that the compound had as marked an activity with warfarin-resistant common rats as coumatetralyl had with non-resistant animals. Feeding tests confirmed that 0.005% would be a near-optimal concentration for field use, although there was some evidence of unpalatability.Results with ship rats and house mice were less favourable. Trials with enclosed colonies of warfarin-resistant mice confirmed the laboratory finding that although difenacoum was more effective than all other currently used anticoagulants, it was unlikely to give complete control.It is concluded that difenacoum is a valuable new rodenticide, especially for controlling warfarin-resistant common rats.


Zoology ◽  
2013 ◽  
Vol 116 (5) ◽  
pp. 307-315 ◽  
Author(s):  
Liang-Kong Lin ◽  
Gwo-Chin Ma ◽  
Tze-Ho Chen ◽  
Wen-Hsiang Lin ◽  
Dong-Jay Lee ◽  
...  

1986 ◽  
Vol 96 (3) ◽  
pp. 467-473 ◽  
Author(s):  
A. P. Buckle

SUMMARYThe anticoagulant rodenticide flocoumafen was tested against warfarin-resistant Norway rats (Rattus norvegicus Berk.) infesting farm buildings. Complete control was obtained in 10–21 days (mean 14·2 days) in six treatments in which baits poisoned with 0·005% flocoumafen were maintained, in surplus, until rats ceased to feed from them. A further six treatments, in which the application of poisoned bait was restricted to periodic placements of 50 g, were also completely successful in 15–30 days (mean 21·0 days). Less poisoned bait was used in the restricted flocoumafen treatments than in the unrestricted treatments but the time taken to control the rat infestations was significantly longer.


1980 ◽  
Vol 84 (3) ◽  
pp. 347-354
Author(s):  
B. D. Rentnison ◽  
R. Redfern ◽  
A. C. Dubock ◽  
J. E. Gill ◽  
C. G. J. Richards

SUMMARYLaboratory tests indicated that the optimum concentration for pyriminyl in rat baits was between 1% and 3%. In field trials in which 0·5% pyriminyl (the concentration in commercial use) was compared with 2·5% zinc phosphide for the control of rats on farms, the pyriminyl treatments were significantly less effective than the zinc phosphide even when the poisoned baits were left down for 7 days instead of 1 day after prebaiting. Both poisons were as effective in medium oatmeal bait as they were in medium oatmeal containing 5% corn oil and 5% sugar.


1974 ◽  
Vol 73 (3) ◽  
pp. 353-360 ◽  
Author(s):  
F. P. Rowe ◽  
F. J. Smith ◽  
T. Swinney

SummaryA combination of calciferol (vitamin D2) and warfarin, each at 0·025% in medium oatmeal bait, failed to control six of seven house-mouse (Mus musculus L.) populations infesting urban and farm buildings. In three further treatments with both calciferol and warfarin at 0·05 % in dehusked canary seed bait plus 5% corn oil, mortality, estimated from the consumption of pre- and post-treatment census bait, ranged between 94·2 and 97·4%. Finally, among sixteen treatments done with calciferol at 0·1% and warfarin at 0·025% in various cereal baits, the best results (97·0–100%) were obtained in six treatments where the bait-base was whole canary seed; this was so whether the poison bait was applied directly or after a 3-day pre-baiting period. It is concluded that calciferol at 0·1 % plus warfarin at 0·025 % is an effective combination against house-mice, especially when used with whole canary seed. The role played by warfarin in the poison mixture needs to be investigated further.


1981 ◽  
Vol 87 (2) ◽  
pp. 171-177 ◽  
Author(s):  
F. P. Rowe ◽  
C. J. Plant ◽  
A. Bradfield

SummaryLaboratory and field trials were conducted to determine the efficacy of the anticoagulant rodenticide bromadiolone against the house mouse (Mus musculus). In laboratory feeding tests, family groups of warfarin-resistant mice maintained in pens and conditioned to feeding on plain foods were offered pinhead oatmeal bait containing bromadiolone at 0·005%. Overall mortality in replicated 21-day poison treatments was 55/58 or 94·8%. Six field trials were carried out, using the same poison bait, against mice infesting farm buildings. Treatment success, estimated from the results of census baitings conducted before and after treatment, ranged between 60·4% and 100%, mean 92·4%. In equivalent field trials using difenacoum, another newly developed anticoagulant rodenticide, the control achieved ranged between 70·2% and 100%, mean 96·0%.Five field trials, three involving bromadiolone and two difenacoum, were not completely successful and the surviving mice were removed for laboratory examination. In 21-day toxicity tests, each animal was fed the poison bait offered to it earlier in the field. Bromadiolone and difenacoum gave kills of 12/21 (57·1%) and 9/11 (81·8%) respectively. The possible emergence of mouse populations resistant to these anticoagulants is considered.


2004 ◽  
Vol 70 (11) ◽  
pp. 6944-6947 ◽  
Author(s):  
Eva M�ller Nielsen ◽  
Marianne N. Skov ◽  
Jesper J. Madsen ◽  
Jens Lodal ◽  
J�rgen Br�chner Jespersen ◽  
...  

ABSTRACT Wild animals living close to cattle and pig farms (four each) were examined for verocytotoxin-producing Escherichia coli (VTEC; also known as Shiga toxin-producing E. coli). The prevalence of VTEC among the 260 samples from wild animals was generally low. However, VTEC isolates from a starling (Sturnus vulgaris) and a Norway rat (Rattus norvegicus) were identical to cattle isolates from the corresponding farms with respect to serotype, virulence profile, and pulsed-field gel electrophoresis type. This study shows that wild birds and rodents may become infected from farm animals or vice versa, suggesting a possible role in VTEC transmission.


1982 ◽  
Vol 89 (2) ◽  
pp. 295-301 ◽  
Author(s):  
J. H. Greaves ◽  
D. S. Shepherd ◽  
R. Quy

SUMMARYTrials of rodenticidal baits containing 50 p.p.m. difenacoum, 50 p.p.m. bromadiolone or 20 p.p.m. brodifacoum were carried out on farmsteads against populations of Rattus norvegicus containing difenacoum-resistant individuals. Six difenacoum treatments failed in 14–42 days of baiting. Two treatments with bromadiolone succeeded in 23 and 33 days, but four further treatments lasting 35–56 days failed to eradicate the populations. Brodifacoum gave virtually complete control of six populations in 21–73 days and of the ten residual populations left behind by the other two compounds, after baiting for a further 11–85 days. The performance of both bromadiolone and brodifacoum was well below that reported by previous investigators, indicating the possibility of low-grade resistance to these compounds in the difenacoum-resistant strain.


1974 ◽  
Vol 73 (1) ◽  
pp. 49-52 ◽  
Author(s):  
F. P. Rowe ◽  
T. Swinney ◽  
A. Bradfield

SUMMARYThe performance of the rodenticide 5-p-chlorophenyl silatrane at 0.5% in a wholemeal flour/pinhead oatmeal/corn oil bait was compared with that of zinc phosphide at 3% in the same base in poison treatments carried out against urban infestations of the house mouse (Mus musculus L.). Each poison treatment was conducted for 1 day and after 3 days' pre-baiting. The success of the treatments was assessed from census baitings conducted before and after treatment. Treatment success varied considerably with both poisons used but in general 5-p-chlorophenyl silatrane proved to be at least as effective as zinc phosphide, a commonly used acute rodenticide for the control of mice.


1974 ◽  
Vol 73 (1) ◽  
pp. 39-43 ◽  
Author(s):  
J. H. Greaves ◽  
R. Redfern ◽  
H. Tinworth

SUMMARYThe properties of 5-p-chlorophenyl silatrane as a rodenticide against Rattus norvegicus and Mus musculus were investigated in the laboratory. The high oral toxicity of the compound was confirmed. When the compound was given to laboratory rats and mice by stomach tube at lethal dosages, signs of poisoning were observed within a minute. When caged wild rats and mice were given a choice between plain and poisoned baits the optimum rodenticidal concentration in the bait was about 0.5% for both species, producing 50% mortality in wild rats and 95% mortality in wild mice. The results are discussed in relation to safety in use and the probable effectiveness of the compound as a rodenticide in field conditions.


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