Cervical lymphadenopathy secondary to atypical mycobacteria in children

1996 ◽  
Vol 110 (1) ◽  
pp. 48-51 ◽  
Author(s):  
R. Benson-Mitchell ◽  
G. Buchanan
Keyword(s):  
Differential Diagnosis ◽  
Lymph Node ◽  
Malignant Disease ◽  
Cervical Lymphadenopathy ◽  
Surgical Excision ◽  
Definitive Diagnosis ◽  
Atypical Mycobacteria ◽  
Complete Surgical Excision ◽  
Immunocompromised Child

AbstractNon-tuberculous mycobacterial (NTM) infections usually present as an enlarged lymph node in the neck of a non-immunocompromised child. The differential diagnosis includes bacterial adenitis, malignant disease and tuberculosis. The definitive diagnosis relies upon isolating the organisms in culture. The treatment is complete surgical excision with, or without, anti-tuberculous chemotherapyTen cases of NTM infections are presented with a discussion of the aetiology and treatment of this condition.

scholarly journals Rosai-Dorfman disease mimicking images of meningiomas: Two case reports and literature review

2021 ◽  
Vol 12 ◽  
pp. 292
Author(s):  
Rafael Trindade Tatit ◽  
Paulo Eduardo Albuquerque Zito Raffa ◽  
Giovana Cassia de Almeida Motta ◽  
André Alexandre Bocchi ◽  
Júlia Loripe Guimaraes ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Reports ◽  
Central Nervous System Involvement ◽  
Cervical Lymphadenopathy ◽  
Surgical Excision ◽  
Definitive Diagnosis ◽  
Rosai Dorfman Disease ◽  
Intracranial Involvement ◽  
Radiological Images ◽  
The Central Nervous System

Background: Rosai-Dorfman disease (RDD) is a rare non-Langerhans cell histiocytic proliferative disorder classically as a massive cervical lymphadenopathy. However, over the years, extranodal locations were confirmed with the central nervous system involvement in less than 5% of cases, which is marked as a significant differential diagnosis of meningiomas, with which they are widely confused due to the similarity of their radiological images. Case Description: We report a 37-year-old man and 45-year-old man who were diagnosed with intracranial RDD but whose radiological images mimic meningiomas, requiring anatomopathological and tumor’s immunohistochemistry for definitive diagnosis. Moreover, a review of 184 publications with 285 cases of intracranial involvement of this disease was also performed, comparing these findings with those brought in the previous studies. Conclusion: Intracranial Rosai-Dorfman tumors should always be remembered as differential diagnosis of meningiomas since they are similar radiologically and macroscopically. Once remembered and diagnosed, the lesion must be treated following the same pattern of resection done in meningiomas and, treatment’s differences will not occur in the surgical excision technique, but in complementary chemotherapy implementation, radiotherapy, and even with radiosurgery aid, depending on the case. Thus, it is possible to obtain better results than with just the isolated surgical procedure.

scholarly journals Extensive parapharyngeal and skull base neuroglial ectopia; a challenge for differential diagnosis and treatment: case report

2010 ◽  
Vol 128 (5) ◽  
pp. 302-305 ◽  
Author(s):  
Giulianno Molina de Melo ◽  
Gabrielle do Nascimento Holanda Gonçalves ◽  
Ricardo Antenor de Souza e Souza ◽  
Danilo Anunciatto Sguillar
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Skull Base ◽  
Infratemporal Fossa ◽  
Newborn Infants ◽  
Surgical Excision ◽  
Neck Mass ◽  
Oral Feeding ◽  
Feeding Difficulties ◽  
Complete Surgical Excision

CONTEXT: Neuroglial ectopia has been defined as a mass composed of differentiated neuroectodermal tissue isolated from the spinal canal or cranial cavity and remains rare. This lesion has to be considered in the differential diagnosis among newborn infants with classical symptoms of respiratory distress, neck mass and feeding difficulties. We present a rare case of extensive parapharyngeal and skull base neuroglial ectopia in 6-month-old girl who presented respiratory and feeding obstruction at birth. CASE REPORT: A six-month-old girl who presented upper respiratory and feeding obstruction at birth and was using tracheostomy and gastrostomy tubes was referred to our institution. Complete surgical excision of the mass consisted of a transcervical-transparotid approach with extension to the infratemporal fossa by means of a lateral transzygomatic incision, allowing preservation of all vital neurovascular structures. The anatomopathological examination showed a solid mass with nests of neural tissue, with some neurons embedded in poorly encapsulated fibrovascular stroma, without mitotic areas, and with presence of functioning choroid plexus in the immunohistochemistry assay. Neurovascular function was preserved, thus allowing postoperative decannulation and oral feeding. Despite the large size of the mass, the child has completed one year and six months of follow-up without complications or recurrence. Neuroglial ectopia needs to be considered in diagnosing airway obstruction among newborns. Surgical treatment is the best choice and should be performed on clinically stable patients. An algorithm to guide the differential diagnosis and improve the treatment was proposed.

scholarly journals Angioleiomyoma of the Larynx: A Case Report and Literature Review

2020 ◽  
Vol 99 (10) ◽  
pp. 658-663
Author(s):  
Federica Perardi ◽  
Giuseppe Abbate ◽  
Leonardo R. Iannuzzelli ◽  
Rossella Contini ◽  
Manuela De Munari ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Differential Diagnosis ◽  
Smooth Muscle ◽  
Case Report ◽  
Gold Standard ◽  
Carbon Dioxide Laser ◽  
Standard Treatment ◽  
Surgical Excision ◽  
Laser Technology ◽  
Complete Surgical Excision

Angioleiomyoma is a benign smooth muscle and vessel tumor; laryngeal localization is extremely rare with only 24 cases described in the literature; moreover, it should be considered in the differential diagnosis of laryngeal mass. Endoscopic complete surgical excision with dissection along capsule is now considered the gold-standard treatment for small and well-circumscribed laryngeal angioleiomyoma. We present a case of laryngeal angioleiomyoma successfully treated with carbon dioxide laser technology which resulted in a bleeding reduction and adequate hemostasis with less tissue damage and good functional outcome.

The Nasolabial Cyst-Nasal Hamartoma

1987 ◽  
Vol 96 (3) ◽  
pp. 268-272 ◽  
Author(s):  
Daniel B. Kuriloff
Keyword(s):  
New York ◽  
Differential Diagnosis ◽  
Nasal Obstruction ◽  
Maxillary Sinusitis ◽  
Surgical Excision ◽  
Odontogenic Cysts ◽  
Facial Deformity ◽  
Developmental Origin ◽  
Complete Surgical Excision

The nasolabial cyst is an uncommon midfacial cyst. Twenty-six patients with nasolabial cysts were treated at the New York Eye and Ear infirmary from 1969 to 1986. Most of these lesions manifested facial deformity, unilateral nasal obstruction, and pain when infected. The nasolabial cyst is often unrecognized or confused with other intranasal masses, or fissural and odontogenic cysts. Infection of these lesions—which occurred in 50% of the patients—may mimic facial cellulitis, periodontal abscess, acute maxillary sinusitis, or nasal furuncies. This cyst is considered to be a hamartoma because of its developmental origin from entrapped epithelium in an embryonic fusion plane. Simple aspiration invariably leads to recurrence, and complete surgical excision is the accepted treatment. The nasolabial cyst should be considered in the differential diagnosis of intranasal masses, midface infections, and swelling in the nasolabial area.

A LARGE SCALP MYXOID NEUROFIBROMA AN UNUSUAL PRESENTATION IN A MIDDLE- AGED PATIENT: A RARE CASE REPORT

2021 ◽  
pp. 18-20
Author(s):  
Subhabrata Das ◽  
Mala Mistri ◽  
Sukanta Sikdar
Keyword(s):  
Differential Diagnosis ◽  
S100 Protein ◽  
Surgical Excision ◽  
Fluctuation Test ◽  
Complete Surgical Excision ◽  
Rare Case Report ◽  
Choice Of Treatment ◽  
The Face ◽  
Scalp Location ◽  
Giant Size

The transformed cells in a neoplasm, whether benign or malignant, often resemble each other, as though all had been derived from a single progenitor, consistent with the monoclonal origin of the tumor. Myxoid neurobroma (MN) is a benign tumor of perineural origin, which is demonstrated by positive immunohistochemical staining for S100 protein. The most common locations are the face, shoulder, anus, periungual, and feet. To our knowledge, this is the first report of an MN in the scalp, which is a very rare location that has been reported earlier. The differential diagnosis of the tumor at this location MN should be kept in mind. This 56 years old male who presented with a large swelling in the scalp (occipital region) which extended to the nape of nack for last 3 years which is gradually increasing in size along with heaviness, intermittent severe pain in the head. Clinically (25x20) cm size swelling in the occipital area and extending to the nape of the neck. The swelling is nontender. It is ovoid in shape . Soft cystic in consistency, the surface is smooth, margins are well dened, the mobility is absent. Fluctuation test is negative but the swelling is brilliantly transilluminant. CONCLUSION: We report this case because of the rarity of both the tumor and its scalp location and also a giant size and to provide a review of the literature. This case study illustrates that any slowly progressing swelling in an unusual location should have been properly investigated and complete surgical excision is the preferred choice of treatment for future recurrence. The MN should be included in the differential diagnosis of tumors at this location.

scholarly journals Conjunctival keratoacanthoma

2004 ◽  
Vol 59 (3) ◽  
pp. 135-137 ◽  
Author(s):  
Fernanda Braga Perdigão ◽  
Paulo de Tarso P. Pierre-Filho ◽  
Renato José Mendonça Natalino ◽  
Roberto Caldato ◽  
Marcelo Torigoe ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Differential Diagnosis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Safety Margin ◽  
Surgical Excision ◽  
Complete Surgical Excision ◽  
Rare Differential Diagnosis

Keratoacanthoma generally occurs on the skin; it is rarely found in the conjunctiva. A case of a 34-year-old woman with a rapidly growing conjunctival mass is reported. The tumor was excised with a safety margin to exclude squamous cell carcinoma. Histopathologically it was crateriform and consistent with atypical keratoacanthoma. There has been no recurrence in 2 years of follow-up. Conjunctival keratoacanthoma is rare; differential diagnosis of conventional squamous cell carcinoma and keratoacanthoma can be difficult. We recommend complete surgical excision and careful follow-up of crateriform squamous proliferations.

scholarly journals Castleman's Disease: A Case Report of the Unicentric Type

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
J. Gomez-Ramirez ◽  
M. Posada ◽  
L. Sanchez-Urdazpal ◽  
E. Martin-Perez ◽  
L. Del Campo ◽  
...  
Keyword(s):  
Lymph Node ◽  
Castleman’S Disease ◽  
Surgical Excision ◽  
Castleman's Disease ◽  
Angiofollicular Lymph Node Hyperplasia ◽  
Human Herpes Virus 8 ◽  
Complete Surgical Excision ◽  
Immunodeficiency Virus ◽  
Generalized Lymphadenopathy ◽  
Aggressive Clinical Course

Castleman's disease, or angiofollicular lymph node hyperplasia, is a relatively rare disorder characterized by the benign proliferation of lymphoid tissue related to the chronic human herpes virus 8 (HHV-8) infection and the human immunodeficiency virus (HIV). Two clinical entities have been described: a unicentric presentation with the disease confined to a single anatomic lymph node and a multicentric presentation characterized by generalized lymphadenopathy and a more aggressive clinical course. Also, three histopathological subtypes have been described: hyaline-vascular, plasma cell, and a mixed variant. Preoperative diagnosis of hyaline-vascular Castleman's disease is difficult, and the definitive result is based on postoperative pathological findings. The gold standard therapy is the complete surgical excision.

Mycobacterium marches back

1995 ◽  
Vol 109 (1) ◽  
pp. 5-13 ◽  
Author(s):  
R. Gareth Williams ◽  
Tony Douglas-Jones
Keyword(s):  
Differential Diagnosis ◽  
Hiv Infection ◽  
Drug Treatment ◽  
Head And Neck ◽  
World Wide ◽  
Cervical Lymphadenopathy ◽  
Atypical Mycobacteria ◽  
Recent Advances

AbstractThe resurgence of tuberculosis world-wide and its association with HIV infection means a greater likelihood of otolaryngologists encountering the disease in one form or another. In this review the features of primary and secondary tuberculosis in various head and neck sites are described, and recent advances in diagnosis are discussed. For the otolaryngologists other important aspects such as infections with atypical mycobacteria, the differential diagnosis of cervical lymphadenopathy in HIV-infected patients, recently recognized problems in drug treatment, and the role of surgery in head and neck tuberculosis are also discussed.

scholarly journals Tislelizumab Combination With Chemotherapy Successfully Converted Unresectable Advanced Penile Cancer Into Complete Surgical Excision: a Case Report and Literature Review

2021 ◽  
Author(s):  
Xiang-Yu Long ◽  
Shuang Zhang ◽  
Lian-sha Tang ◽  
Xiang Li ◽  
Jiyan Liu
Keyword(s):  
Lymph Node ◽  
Inguinal Lymph Node ◽  
Locally Advanced ◽  
Surgical Excision ◽  
Complete Response ◽  
Conversion Therapy ◽  
Inguinal Lymph Node Dissection ◽  
Complete Surgical Excision ◽  
Neoadjuvant Immunotherapy ◽  
Penile Squamous Cell Carcinoma

Abstract Background: Locally advanced Penile squamous cell carcinoma (PSCC) with unresectable inguinal lymph nodes has a poor prognosis, and benefits from surgical treatment alone. Effective conversion therapy regimens are urgently needed.Case Presentation: We report a locally advanced PSCC patient with bulky, fixed inguinal lymph node metastasis complicated within genial skin ulcers, who completed inguinal lymph node dissection and achieved pathologically complete response via conversion therapy by immunotherapy plus chemotherapy.Conclusion: For unresectable locally advanced PSCC, neoadjuvant immunotherapy combined with chemotherapy is a potential treatment approach. Biomarkers of immune efficacy need to be explored. At the same time, clinical trials are needed to test the notions.

scholarly journals A rare presentation of small diaphragmatic epidermoid cyst with extremely elevated serum CA19-9 level

2020 ◽  
Vol 102 (2) ◽  
pp. e23-e25
Author(s):  
M El-Khoury ◽  
A Bohlok ◽  
YA Sleiman ◽  
P Loi ◽  
E Coppens ◽  
...  
Keyword(s):  
Epidermoid Cyst ◽  
Elevated Serum ◽  
Surgical Excision ◽  
Definitive Diagnosis ◽  
The Body ◽  
Intraluminal Pressure ◽  
En Bloc ◽  
Rare Presentation ◽  
Epidermoid Cysts ◽  
Complete Surgical Excision

Epidermoid cysts are rare lesions that can occur anywhere in the body. They are associated with elevated serum levels of CA 19-9. The spleen represents the most common site of intra-abdominal localisation. Only two cases of diaphragmatic epidermoid cyst are reported in the literature. We present the case of a 61-year-old woman with a small suprasplenic subdiaphragmatic cyst discovered during the investigation of left flank pain. The establishment of an adequate diagnosis was challenging due to the difficulty in specifying the exact localisation of the cyst, the extremely elevated CA 19-9 level of 19,000 and the high uptake on 18-fluoro-2-deoxy-D-glucose positron emission tomography. The definitive diagnosis followed complete surgical excision. Intra-abdominal epidermoid cysts are usually discovered incidentally on imaging for another reason. The cyst is lined by squamous epithelium responsible for the secretion of CA 19-9. The elevation of serum CA 19-9 is due to small rupture or increased intraluminal pressure followed by diffusion to the bloodstream. Surgery with en-bloc resection represents the optimal treatment to avoid any risk of recurrence. The definitive diagnosis is established by demonstrating positive immunohistopathological staining of epithelial cell to CA 19.9.

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