scholarly journals A study of bacterial pathogens and antibiotic susceptibility patterns in chronic suppurative otitis media

2017 ◽  
Vol 132 (1) ◽  
pp. 41-45 ◽  
Author(s):  
M R Mofatteh ◽  
F Shahabian Moghaddam ◽  
M Yousefi ◽  
M H Namaei
Keyword(s):  
Otitis Media ◽  
Antibiotic Susceptibility ◽  
Chronic Suppurative Otitis Media ◽  
Bacterial Isolates ◽  
Suppurative Otitis Media ◽  
Microbiological Methods ◽  
Significant Difference ◽  
Antibiotic Susceptibility Patterns ◽  
Periodic Evaluation ◽  
Susceptibility Patterns

AbstractObjective:To assess the frequency of bacterial agents in chronic suppurative otitis media and the antibiotic susceptibility patterns of isolates among patients.Methods:A total of 185 patients clinically diagnosed with chronic suppurative otitis media were interviewed and middle-ear effusion samples were collected using sterile swabs. All bacterial isolates were identified by conventional microbiological methods. Antibiotic susceptibility patterns of the isolates were determined by Kirby–Bauer disc diffusion.Results:Staphylococci spp. (64.9 per cent) were the most prevalent bacteria isolated, followed by Klebsiella spp. (12.9 per cent) and Pseudomonas aeruginosa (10.3 per cent). The most effective antibiotic for treatment of bacterial chronic suppurative otitis media was ciprofloxacin. Statistical analysis showed no significant difference in bacterial infestations among chronic suppurative otitis media patients and the antimicrobial susceptibility patterns of the bacterial isolates based on gender and age (p > 0.05).Conclusion:Our findings highlight the importance of a continuous and periodic evaluation of the bacteriological profile and antibiotic susceptibility patterns in chronic suppurative otitis media patients for efficacious treatment of the infection.

scholarly journals Bacteriological profile and their antibiotic susceptibility pattern in chronic suppurative otitis media (TTD) in a tertiary care hospital

2019 ◽  
Vol 5 (4) ◽  
pp. 871
Author(s):  
Sriram Govindaraj ◽  
Jinu Vadakkanethu Iype ◽  
Srinivasa V. ◽  
Jayendiran S.
Keyword(s):  
Otitis Media ◽  
Antimicrobial Susceptibility ◽  
Antibiotic Susceptibility ◽  
Chronic Suppurative Otitis Media ◽  
Care Hospital ◽  
Bacterial Isolates ◽  
Susceptibility Pattern ◽  
Suppurative Otitis Media ◽  
Antimicrobial Susceptibility Pattern ◽  
The Common

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media (CSOM) is one of the common infective conditions which can cause many complications if not treated properly. Improper use of antibiotic among the common population has led to many drug resistant organisms; therefore it is necessary to study the antimicrobial susceptibility pattern before treating the patient with CSOM. Aim of the study was to identify the bacterial isolates causing CSOM in tubo tympanic disease and to study their antimicrobial susceptibility pattern.</p><p class="abstract"><strong>Methods:</strong> The study was carried out in ENT department in Vinayaka Mission Medical College, Karaikal from July 2018 till December 2018 for six months. 60 patients of CSOM (TTD) with ear discharge attending the ENT Out Patient Department were included in the study. Swabs were collected for culture and sensitivity. Bacterial isolates were identified using standard methods and antibiotic susceptibility testing were done.  </p><p class="abstract"><strong>Results:</strong> Pseudomonas species was the most predominant organism, which was seen in 19 patients (38%) followed by <em>Escherichia coli</em> (22%), <em>Staphylococcus aureus</em> (18%), <em>Klebsiella species</em> (10%).</p><p class="abstract"><strong>Conclusions:</strong> A continuous and periodic evaluation of microbiological pattern and their antibiotic sensitivity pattern prevalent in local area, helps in prescribe proper antibiotics for successful treatment of CSOM and thus minimizing its complications and emergence of resistant strains.</p><p class="abstract"> </p>

Perbedaan sensitivitas tetes telinga antibiotik terhadap Pseudomonas aeruginosa pada otitis media supuratif kronik

2012 ◽  
Vol 42 (2) ◽  
Author(s):  
Anton Budhi Darmawan ◽  
Dwi Utami Anjarwati
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Chronic Suppurative Otitis Media ◽  
Test Results ◽  
Sectional Study ◽  
Suppurative Otitis Media ◽  
Number Of Patients ◽  
Significant Difference ◽  
Cochran Test ◽  
Post Hoc

Background: Chronic suppurative otitis media (CSOM) is one infectious disease of the middle ear, most commonly caused by Pseudomonas aeruginosa. A high number of patients come to the ENT outpatient clinic with active benign type of CSOM. The bacteria Pseudomonas aeruginosa is capable of producing biofilm which protects itself from penetration of antibiotics, and therefore creates resistance towards antibiotics and difficult to eradicate. Objective: The aim of this study was to compare the sensitivity levels of chloramphenicol, polymyxin-neomycin, cyprofloxacin and ofloxacine against Pseudomonas aeruginosa in patients with active benign type CSOM in ENT clinic. Method: The method used was across sectional study on 25 patients, from August 2010 until December 2010. Samples were taken withear swab and then put on sensitivity test to chloramphenicol, polymyxin-neomycin, cyprofloxacin andofloxacine using the diffusion disc method. The analysis used in this study was Cochran test. Results: Results showed a significant difference in sensitivity among chloramphenicol (38,70%), polymyxinneomycin(83,87%),cyprofloxacin(90,32%)andofloxacin(58,06%)withp=0,000(p<0,05).PostHocanalysisusing the Mc Nemar indicated that there were significant differences in sensitivity betweenpolymyxin-neomycin to chloramphenicol with p=0,000 (p<0,05), ciprofloxacin to chloramphenicol andciprofloxacin to ofloxacine with p= 0,002, but there were no significant differences between cyprofloxacinto polymyxin-neomycin with p=0,687, polymyxin-neomycin to ofloxacin p=0.057 and ofloxacin tochloramphenicol p=0,109.   There were significant differences in antibiotic ear dropssensitivity to Pseudomonas aeruginosa in patients with active benign type of CSOM. Cyprofloxacin andpolymyxin-neomycin were more sensitive than ofloxacin and chloramphenicol. Keywords: Pseudomonas aeruginosa, active benign type of chronic suppurative otitis media, antibioticear drops.  Abstrak :  Latar belakang: Otitis media supuratif kronik (OMSK) merupakan penyakit infeksi kronik telinga tengah yang sering dijumpai di klinik THT. Penyebab tersering OMSK adalah bakteri Pseudomonasaeruginosa. Pseudomonas aeruginosa mempunyai kemampuan untuk membentuk biofilm yangmelindunginya dari penetrasi antibiotik sehingga menimbulkan resistensi terhadap antibiotik dan sulituntuk eradikasinya. Tujuan: Untuk mengetahui perbandingan tingkat sensitivitas kloramfenikol,polimiksin-neomisin, ciprofloksasin dan ofloksasin terhadap isolat Pseudomonas aeruginosa padapasien OMSK benigna aktif di klinik THT RSMS. Metode: Metode yang digunakan adalah crosssectional terhadap 29 pasien OMSK di klinik THT RSMS periode bulan Agustus 2010 - Desember2010. Pengambilan sampel dilakukan dengan swab telinga. Uji sensitivitas terhadap kloramfenikol,polimiksin-neomisin, ciprofloksasin dan ofloksasin dilakukan dengan metode cakram secara difusi.Analisis yang digunakan dalam penelitian ini adalah Cochran dan analisis post hoc. Hasil: Didapatkansensitivitas kloramfenikol sebesar 38,70%, polimiksin-neomisin sebesar 83,87%, ciprofloksasin sebesar90,32% dan ofloksasin sebesar 58,06% dengan p=0,01 (P<0,05), yang menunjukkan adanya perbedaansensitivitas yang bermakna antara kloramfenikol, polimiksin-neomisin, ciprofloksasin dan ofloksasinterhadap Pseudomonas aeruginosa. Analisis post hoc menggunakan Mc Nemar menunjukkan bahwaterdapat perbedaan sensitivitas yang bermakna antara tetes telinga polimiksin-neomisin terhadapkloramfenikol, dan ciprofloksasin terhadap kloramfenikol p=0,000 (p<0,05), serta terdapat perbedaanyang bermakna antara tetes telinga ciprofloksasin terhadap ofloksasin, p=0,002, tetapi tidak terdapatperbedaan yang bermakna antara ciprofloksasin terhadap polimiksin-neomisin, p=0,687, polimiksinneomisinterhadap ofloksasin p=0,057, dan kloramfenikol terhadap ofloksasin p=0,109. Kesimpulan:Terdapat perbedaan sensitivitas yang bermakna tetes telinga antibiotik terhadap Pseudomonas aeruginosa pada pasien OMSK benigna aktif. Ciprofloksasin dan polimiksin-neomisin tetes telinga mempunyai sensitivitas yang lebih baik dibanding ofloksasin dan kloramfenikol. Kata kunci: Pseudomonas aeruginosa, otitis media supuratif kronik, tetes telinga antibiotik 

Therapeutic Management of Chronic Suppurative Otitis Media with Otic Drops

1993 ◽  
Vol 109 (1) ◽  
pp. 77-82 ◽  
Author(s):  
David O. Merifield ◽  
Nancy J. Parker ◽  
Nannette C. Nicholson
Keyword(s):  
Otitis Media ◽  
Human Subjects ◽  
Bone Conduction ◽  
Chronic Suppurative Otitis Media ◽  
Suppurative Otitis Media ◽  
Hearing Sensitivity ◽  
Significant Difference ◽  
Before And After ◽  
Ventilation Tubes ◽  
Bone Conduction Hearing

The use of potentially ototoxic topical drugs is controversial. Few experimental reports of audiometric data from human subjects exist. The purpose of this study is to determine if a significant difference between bone conduction hearing sensitivity before and after otic drop treatment for children with chronic suppurative otitis media and patent ventilation tubes exists. A statistical analysis of sensorineural threshold status after treatment of chronic suppurative otitis media with otic drops is presented.

Effect of aerobic bacteriology on the clinical presentation and treatment results of chronic suppurative otitis media

1996 ◽  
Vol 110 (4) ◽  
pp. 315-318 ◽  
Author(s):  
Eero Vartiainen ◽  
Jukka Vartiainen
Keyword(s):  
Surgical Treatment ◽  
Otitis Media ◽  
Clinical Presentation ◽  
Chronic Suppurative Otitis Media ◽  
Long Term Results ◽  
Treatment Results ◽  
Suppurative Otitis Media ◽  
Hearing Results ◽  
Significant Difference

AbstractThe effect of aerobic bacteriology on the clinical presentation, complications of the disease and long-term results of surgical treatment was assessed in a cohort of 368 patients with chronic suppurative otitis media. Bacteriological findings showed no significant difference between child and adult patients. Staphylococcus aureus was isolated in cholesteatoma ears more frequently than Pseudomonas aeruginosa, in chronic ears without cholesteatoma the situation was reversed. Bacteriological findings had no significant effect on the incidence of complications caused by the disease. Failures after surgical treatment were most common in Pseudomonas ears. The bacteriology had no significant effect on pre-operative hearing levels nor postoperative hearing results. It was concluded that, in order to improve results of chronic ear sugery, more attention should be paid to pre-operative conservative treatment of chronically discharging ears, especially those infected by P. aeruginosa.

Sign in / Sign up

Export Citation Format

Share Document