scholarly journals Preliminary meta-analysis of the effect of fish oil on body weight and body mass index in overweight and obese subjects does not support a link

2013 ◽  
Vol 72 (OCE4) ◽  
Author(s):  
C. J. Harden ◽  
M. E. Barker ◽  
J. M. Russell ◽  
B. M. Corfe
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Fish Oil ◽  
Body Mass ◽  
Meta Analysis ◽  
Obese Subjects

scholarly journals Seaweed Fucoxanthin Supplementation Improves Obesity Parameters in Mild Obese Japanese Subjects

2017 ◽  
Vol 7 (4) ◽  
pp. 246 ◽  
Author(s):  
Shoketsu Hitoe ◽  
Hiroshi Shimoda
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Placebo Group ◽  
Body Mass ◽  
Subcutaneous Fat ◽  
Abdominal Fat ◽  
Thigh Circumference ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Obese Subjects

Background: Fucoxanthin is a seaweed xanthophyll that has demonstrated an anti-obesity effect in rodents. However, clinical investigations of its influence on mildly obese subjects has not been performed. We conducted a clinical trial of fucoxanthin supplementation in Japanese obese subjects. Methods: We examined the effect of fucoxanthin (1 or 3 mg daily) in a double-blind placebo-controlled study. Capsules containing fucoxanthin or placebo capsules were administered for 4 weeks to male and female Japanese adults with a body mass index (BMI) of more than 25 kg/m2. Before and after treatment, the body weight, body composition, abdominal fat area, and the circumferences of the neck, arm, and thigh were evaluated.Results: There was significant reduction of the relative (ratio versus before treatment) body weight, BMI, and visceral fat area in the 3 mg/day fucoxanthin group compared to the placebo group. Relative values of total fat mass, subcutaneous fat area, waist circumference, and right thigh circumference were also significantly lower in the 1 mg/day fucoxanthin group than the placebo group. A significant decrease of the absolute right thigh circumference was noted in the 1 mg/day fucoxanthin group compared to the placebo group. In the subjects ingesting fucoxanthin, there were no abnormalities of the blood pressure, pulse rate, blood parameters, and urinalysis parameters, which thereby suggests adverse effects. Conclusions: Fucoxanthin reduced body weight, BMI, and abdominal fat by acting on both visceral and subcutaneous fat. Consequently, Fucoxanthin may be able to improve a moderate overweight state in both men and women. Keywords: Randomized, double-blind, placebo-controlled crossover trial; fucoxanthin; body mass index; body weight; subcutaneous fat; adipose tissue

scholarly journals Body Mass Index and Risk of Gastric Cancer in Asian Adults: A Meta-Epidemiological Meta-Analysis of Population-Based Cohort Studies

2020 ◽  
Vol 52 (2) ◽  
pp. 369-373 ◽  
Author(s):  
Jong-Myon Bae
Keyword(s):  
Gastric Cancer ◽  
Body Mass Index ◽  
Body Weight ◽  
Cohort Studies ◽  
Body Mass ◽  
Meta Analysis ◽  
Population Based ◽  
Overweight And Obesity ◽  
Excess Body Weight ◽  
Inverse Association

PurposeA previous meta-analysis (MA) published in 2009 reported that excess body weight was associated with an increased risk of gastric cancer in non-Asians, but not in Asians. The aim was to conduct a meta-epidemiological MA (MEMA) to evaluate association between excess body weight and the risk of gastric cancer in Asian adults with using the proposed classification of weight by body mass index (BMI) in Asian adults.Materials and MethodsThe selection criteria were population-based prospective cohort studies that measured BMI of cohort participants and evaluated a risk of gastric cancer. Overweight group (OW) and obesity group (OB) were defined as 23.0-24.9 and ≥ 25.0, respectively. A group only showing results for BMI over 23.0 was defined as overweight and obesity group (OWB). Random effect model was applied if I<sup>2</sup> value was over 50%.ResultsAfter four new studies were added through citation discovery tools, seven cohort studies with 21 datasets were selected finally for MEMA. The I<sup>2</sup> value of OW, OB, and OWB were 76.1%, 83.5%, and 97.1%, respectively. Only OWB in men had a I<sup>2</sup> value below 50% (22.5%) and showed a statistical significance with inverse association (summary relative risk, 0.79; 95% confidence interval, 0.77 to 0.81).ConclusionThis MEMA supported the hypothesis that OW might be a protective factor in gastric cancer risk in Asian adults. It will be necessary to conduct additional cohort studies with lengthening follow-up periods and re-analyzing the effect of overweight and obesity classified by the Asian criteria.

Effects of Aerobic Plus Resistance Exercise on Body Composition Related Variables in Pediatric Obesity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2015 ◽  
Vol 27 (4) ◽  
pp. 431-440 ◽  
Author(s):  
Antonio García-Hermoso ◽  
Mairena Sánchez-López ◽  
Vicente Martínez-Vizcaíno
Keyword(s):  
Body Mass Index ◽  
Body Composition ◽  
Body Weight ◽  
Resistance Exercise ◽  
Body Mass ◽  
Fat Mass ◽  
Meta Analysis ◽  
Fat Free Mass ◽  
Exercise Interventions ◽  
Obese Youth

The purpose of this meta-analysis of randomized trials was to determine the effectiveness of aerobic plus resistance exercise interventions on body composition related to variables in overweight and obese youth. A computerized search was made of 7 databases. The analysis was restricted to randomized controlled trials that examined the effect of aerobic and resistance exercise on body composition (body weight, body mass index, fat mass, fat-free mass, and waist circumference) in obese youth. Two independent reviewers screened studies and extracted data. Weighted mean differences (WMD) and 95% confidence intervals were calculated. Nine studies were selected for meta-analysis as they fulfilled the inclusion criteria (n = 365). Aerobic plus resistance exercise interventions (8–24 weeks duration) produced a decrease in body weight (WMD=-3.31 kg), body mass index (WMD=-1.05 kg/m2), and fat mass (WMD=-1.93% and 5.05 kg), but changes in fatfree mass and waist circumference were not observed. These changes were accentuated through programs of at least 60 min of exercise per session, generating greater reductions in body weight (WMD=-4.11 kg), fat mass (WMD=-4.07%), and increase in fat-free mass (WMD = 2.45 kg). This meta-analysis provides insight into the effectiveness of short-term aerobic plus resistance exercise interventions for decreasing body weight, body mass index, and fat mass in pediatric obesity.

scholarly journals The effect of women’s body mass index on pelvic organ prolapse: a systematic review and meta analysis

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Chernet Baye Zenebe ◽  
Wagaye Fentahun Chanie ◽  
Aster Berhe Aregawi ◽  
Tamiru Minwuye Andargie ◽  
Muhabaw Shumye Mihret
Keyword(s):  
Systematic Review ◽  
Body Mass Index ◽  
Body Weight ◽  
Pelvic Organ Prolapse ◽  
Body Mass ◽  
Meta Analysis ◽  
Grey Literature ◽  
Experimental Studies ◽  
Pelvic Organ ◽  
Cross Sectional

Abstract Background Pelvic organ prolapse remains the public health challenge globally. Existing evidences report the effect of woman’s weight on the pelvic organ prolapse inconsistently and this urges the need of pooled body weight effect on the pelvic organ prolapse. Although there was a previous work on this regard, it included papers reported before June 18/2015. Thus, updated and comprehensive evidence in this aspect is essential to devise strategies for interventions. Objective This review aimed at synthesizing evidence regarding the pooled effect of body weight on the pelvic organ prolapsed. Methods For this review, we searched all available articles through databases including PubMed, Web of Sciences, CINAHL, JBI library, Cochran library, PsycInfo and EMBASE as well as grey literature including Mednar, worldwide science, PschEXTRA and Google scholar. We included cohort, case–control, cross-sectional and experimental studies which had been reported between March 30, 2005 to March 30, 2020. In the effect analysis, we utilized random model. The heterogeneity of the studies was determined by I2 statistic and the publication bias was checked by Egger’s regression test. Searching was limited to studies reported in the English language. Results A total of 14 articles with 53,797 study participants were included in this systematic review (SR) and meta analysis (MA). The pooled result of this Meta analyses depict that body mass index (BMI) doesn’t have statistical significant association with pelvic organ prolapse. Conclusion This review point out that women’s body mass index has no significant effect on the development of pelvic organ prolapse. However, the readers should interpret the result with cautions due to the presence of considerable limitations in this work. Trial registration The protocol of this systematic review (SR) and meta analysis (MA) has been registered in PROSPERO databases with the Registration number of CRD42020186951

scholarly journals Association between Primary Hyperparathyroidism and Increased Body Weight: A Meta-Analysis

2005 ◽  
Vol 90 (3) ◽  
pp. 1525-1530 ◽  
Author(s):  
Mark J. Bolland ◽  
Andrew B. Grey ◽  
Greg D. Gamble ◽  
Ian R. Reid
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Primary Hyperparathyroidism ◽  
Body Mass ◽  
English Language ◽  
Meta Analysis ◽  
Control Group ◽  
Language Studies ◽  
Standard Mean Difference ◽  
Age And Sex

Although primary hyperparathyroidism is frequently asymptomatic, it has been associated with an increased prevalence of hypertension, insulin resistance, dyslipidemia, cardiovascular mortality, and cancer. Previously we reported that patients with primary hyperparathyroidism are heavier than age-matched controls. Increased body weight could contribute to the association between primary hyperparathyroidism and these extraskeletal complications. We searched MEDLINE for English language studies published between 1975 and 2003 that reported body weight or body mass index in subjects with primary hyperparathyroidism and a healthy age- and sex-comparable eucalcemic control group. Seventeen eligible studies were identified. Subjects with primary hyperparathyroidism were 3.34 kg (95% confidence interval, 1.97–4.71; P &lt; 0.00001) heavier than controls in 13 studies reporting body weight. In four studies reporting body mass index, subjects with primary hyperparathyroidism had an increased body mass index of 1.13 kg/m2 (−0.29 to 2.55; P = 0.12) compared with controls. Standard mean difference analysis showed that subjects with primary hyperparathyroidism had an increased weight or body mass index of 0.3 sd (0.19–0.40; P &lt; 0.00001) compared with controls. We conclude that patients with primary hyperparathyroidism are heavier than their eucalcemic peers, and that increased body weight may contribute to the reported associations between primary hyperparathyroidism and some extraskeletal complications.

Persistence of altered metabolic responses to beta-endorphin after normalization of body weight in human obesity

1991 ◽  
Vol 124 (2) ◽  
pp. 159-165 ◽  
Author(s):  
Dario Giugliano ◽  
Domenico Cozzolino ◽  
Roberto Torella ◽  
Pierre J Lefebvre ◽  
Paul Franchimont ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Body Mass ◽  
Plasma Glucose ◽  
Normal Weight ◽  
Obese Group ◽  
Control Group ◽  
Human Obesity ◽  
C Peptide ◽  
Obese Subjects

Abstract. The responses of plasma glucose, insulin, C-peptide and glucagon to an infusion of human β-endorphin (0.5 mg/h) were studied in 10 formerly obese subjects who had lost 35 kg by dieting (body mass index <25) and compared with those of 10 normal-weight control (body mass index <25) and 10 obese (body mass index >30) subjects. The fasting plasma concentrations of β-endorphin were significantly higher in both the obese and the post-obese group than in the control group. In both obese and post-obese subjects, the infusion of β-endorphin caused significant increases in peripheral plasma glucose, insulin, C-peptide and glucagon concentrations. In the control group, matched for age, sex and weight with the formerly obese group, there was no appreciable change in plasma insulin and C-peptide concentrations during the infusion of β-endorphin, but the rise in plasma glucose was more sustained. Thus, 1. the increased plasma β-endorphin concentrations found in human obesity are not corrected by normalization of body weight; and 2. formerly obese, normal-weight subjects behave as obese subjects in their metabolic and hormonal responses to β-endorphin infusion. The alteration of the opioid system in human obesity may play some role in the predisposition to weight gain.

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