Personality and risk for depression in a birth cohort of 70-year-olds followed for 15 years

2008 ◽  
Vol 38 (5) ◽  
pp. 663-671 ◽  
Author(s):  
P. R. Duberstein ◽  
S. P. Pálsson ◽  
M. Waern ◽  
I. Skoog
Keyword(s):  
Older Adults ◽  
Confidence Interval ◽  
Mood Disorder ◽  
Birth Cohort ◽  
Late Life Depression ◽  
Survival Analyses ◽  
Point Increase ◽  
Significant Depression ◽  
Clinically Significant

BackgroundThe association between personality traits and the first lifetime onset of clinically significant depression has not been studied in older adults.MethodExperienced psychiatrists conducted interviews and chart reviews at baseline and throughout the 15-year follow-up period. Survival analyses were conducted on the presence/absence of a DSM-III-R mood disorder at follow-up.ResultsThere were 59 cases of first lifetime episodes of depression. Analyses showed that Neuroticism [hazard ratio (HR) per one point increase in the Maudsley Personality Inventory (MPI)=1.05, 95% confidence interval (CI) 1.02–1.08] but not Extroversion (HR 1.02, 95% CI 0.97–1.06) amplified risk for mood disorder.ConclusionsThis prospective study on a randomly sampled birth cohort of older adults showed that Neuroticism confers risk for a first lifetime episode of clinically significant depression. Findings have implications for understanding the etiology of late-life depression (LLD) and could also aid in the identification and treatment of people at risk.

A Randomized Controlled Trial Assessing the Evolution of the Weight-Bearing Ankle Dorsiflexion Range of Motion Over 6 Sessions of Talus Mobilizations in Older Adults

2020 ◽  
Vol 100 (4) ◽  
pp. 645-652
Author(s):  
David Hernández-Guillén ◽  
José-María Blasco
Keyword(s):  
Older Adults ◽  
Confidence Interval ◽  
Range Of Motion ◽  
Weight Bearing ◽  
Ankle Dorsiflexion ◽  
Community Dwelling ◽  
Ankle Mobility ◽  
Healthy Community ◽  
Community Dwelling Older Adults

Abstract Background Ankle range of motion declines with age, affecting mobility and postural control. Objective The objective of this study was to investigate the effects of a talus mobilization-based intervention among healthy community-dwelling older adults presenting with limited weight-bearing ankle dorsiflexion range of motion and determine how ankle mobility evolved over the treatment. Design This was a randomized clinical trial. Setting This study was conducted in an outpatient clinic. Participants Community-dwelling, older adults over 60 years of age who had limited ankle mobility participated in this study. Interventions The experimental intervention consisted of 6 sessions of manual therapy applied in the ankle joint. The control group received the same volume of sham treatment. Measurements The primary outcome was the weight-bearing ankle dorsiflexion range of motion as measured using the lunge test. Data were collected at 9 time points: baseline, after each session, and follow-up. Results A total of 36 participants were analyzed. A single session of mobilization increased ankle range of motion by 8 degrees (95% confidence interval = 6 to 11). At the end of the sixth session, this effect had increased slightly to 11 degrees (95% confidence interval = 9 to 13). Significant between-group differences were found throughout the intervention. Limitations Optimal dose and effects from follow-up evaluations for treatment volumes of fewer than 6 sessions remain unknown. Conclusions Six sessions of a talus mobilization-based intervention in healthy community-dwelling older adults found that the greatest mobility gain in terms of the weight-bearing ankle dorsiflexion range of motion is produced after the first session. Additional sessions produce smaller improvements with a slight upward trend. Importantly, the restoration of joint mobility is enhanced over time after the end of the intervention.

Arthritis, Depression, and Falls Among Community-Dwelling Older Adults: Evidence From the Health and Retirement Study

2016 ◽  
Vol 37 (9) ◽  
pp. 1133-1149 ◽  
Author(s):  
Lien T. Quach ◽  
Jeffrey A. Burr
Keyword(s):  
Older Adults ◽  
Health Care Providers ◽  
Community Dwelling ◽  
Health And Retirement Study ◽  
Depression Symptoms ◽  
Care Providers ◽  
Significant Depression ◽  
Nationally Representative ◽  
Clinically Significant ◽  
Retirement Study

The aims of this study were to examine the association between different types of arthritis and falls and to investigate whether clinically significant depression symptoms (CSDS) moderate these relationships. The study used nationally representative data from the 2008 Health and Retirement Study ( n = 7,715, M age = 75, 62% female, and 90% White). Among the respondents, 42% experienced at least one fall during the previous 2 years. About one third had some form of arthritis: 22% osteoarthritis (OA), 4.8% rheumatoid arthritis (RA), 2.3% both OA and RA, and 7.9% with other arthritis types. About one fifth of respondents had CSDS. OA and CSDS are associated with the odds of falling (17% and 29%, respectively), adjusting for socio-demographic characteristics, lifestyle, health conditions, and psychiatric medications. There was no statistically significant interaction between types of arthritis and CSDS. Health care providers should pay attention to managing arthritis, especially OA, and CSDS to prevent falls among older adults.

Relationship Between Insomnia, Depression, and Mortality: A 12-Year Follow-Up of Older Adults in the Community

2000 ◽  
Vol 12 (3) ◽  
pp. 295-306 ◽  
Author(s):  
Lena Mallon ◽  
Jan-Erik Broman ◽  
Jerker Hetta
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Natural History ◽  
Confidence Interval ◽  
Odds Ratio ◽  
Death Rate ◽  
Mortality Data ◽  
Total Death ◽  
History Of

The purpose of the study was to investigate the natural history of insomnia and its association with depression and mortality. In 1983, 1,870 randomly selected subjects aged 45–65 years answered a questionnaire on sleep and health. Of the 1,604 survivors in 1995, 1,244 (77.6%) answered a new questionnaire with almost identical questions. Mortality data were collected for the 266 subjects that had died during the follow-up period. Chronic insomnia was reported by 36.0% of women and 25.4% of men (χ2 = 9.7; p < .01). About 75% of subjects with insomnia at baseline continued to have insomnia at follow-up. Insomnia in women predicted subsequent depression (odds ratio [OR] = 4.1; 95% confidence interval [CI] 2.1–7.2) but was not related to mortality. In men, insomnia predicted mortality (OR = 1.7; 95% CI 1.2–2.3), but after adjustment for an array of possible risk factors, this association was no longer significant. Men with depression at baseline had an adjusted total death rate that was 1.9 times higher than in the nondepressed men (95% CI: 1.2–3.0).

Origins of depression in later life

2005 ◽  
Vol 35 (9) ◽  
pp. 1241-1252 ◽  
Author(s):  
DAN G. BLAZER ◽  
CELIA F. HYBELS
Keyword(s):  
Older Adults ◽  
Stressful Life Events ◽  
Cognitive Distortions ◽  
Late Life ◽  
Later Life ◽  
Late Life Depression ◽  
Younger Adults ◽  
Social Risks ◽  
Clinically Significant ◽  
The Many

Background. Despite the burden of depression in late life, its origins present a paradox to investigators and clinicians alike.Method. We review biological (genetics and heredity factors, neurotransmitter dysfunction, endocrine changes, vascular disorders, and medical co-morbidities), psychological (personality attributes, neuroticism, cognitive distortions, and the lack of emotional control and self-efficacy) and social (stressful life events, bereavement, chronic stress or strain, socio-economic disadvantage and impaired social support) origins of late-life depression based upon an extensive though not exhaustive review of the extant literature. In addition, modifying psychological and social factors are discussed.Results. Older adults appear to be at greater risk for major depression biologically, such as depression resulting from vascular changes, yet the frequency of depression is lower compared to younger adults. Older adults may be protected psychologically due to factors such as socio-emotional selectivity and wisdom, compared to younger adults, and perhaps relatively protected from social risks.Conclusions. A biopsychosocial approach to evaluating the origins of late-life depression is heuristically valuable, a continual reminder of the many factors that contribute to the onset and persistence of clinically significant symptoms in late life.

Chronic subsyndromal depression and risk of dementia in older adults

2020 ◽  
pp. 000486742097276
Author(s):  
Dae Jong Oh ◽  
Ji Won Han ◽  
Jong Bin Bae ◽  
Tae Hui Kim ◽  
Kyung Phil Kwak ◽  
...  
Keyword(s):  
Older Adults ◽  
Confidence Interval ◽  
Late Onset ◽  
Population Based ◽  
Hazard Ratio ◽  
Cognitively Normal ◽  
Subsyndromal Depression ◽  
Poor Outcomes ◽  
Korean Elderly

Objectives: Subsyndromal depression is prevalent and associated with poor outcomes in late life, but its effect on the risk of dementia has barely been investigated. This study is aimed to investigate the effect of subsyndromal depression on dementia risk in cognitively normal older adults and patients with mild cognitive impairment. Methods: Data were collected from a nationwide, population-based, prospective cohort study on a randomly sampled Korean elderly population aged 60 years or older, which has been followed every 2 years. Using 6-year follow-up data of 4456 non-demented elderly, the authors examined the risk of dementia associated with late-onset subsyndromal depression using multivariate Cox proportional hazard models. After standardized diagnostic interviews, subsyndromal depression and dementia were diagnosed by the operational diagnostic criteria and Diagnostic and Statistical Manual of Mental Disorders, 4th edition criteria, respectively. Results: Subsyndromal depression tripled the risk of dementia in non-demented elderly individuals (hazard ratio = 3.02, 95% confidence interval = [1.56, 5.85], p < 0.001). In subgroup analyses, subsyndromal depression was associated with the risk of dementia in cognitively normal participants only (hazard ratio = 4.59, 95% confidence interval = [1.20, 17.54], p = 0.026); chronic/recurrent subsyndromal depression with increasing severity during the follow-up period was associated with the risk of dementia (hazard ratio = 15.34, 95% confidence interval = [4.19, 56.18], p < 0.001). Conclusion: Late-onset subsyndromal depression is a potential predictor of incident dementia when it is chronic or recurrent with increasing severity in cognitively normal older adults.

scholarly journals Seven-year survival analysis of the Global® CAP® (Conservative Anatomic Prosthesis) shoulder resurfacing

2017 ◽  
Vol 10 (2) ◽  
pp. 87-92
Author(s):  
Helen Ingoe ◽  
Philip Holland ◽  
Emma Tindall ◽  
Raymond Liow ◽  
James L Mcvie ◽  
...  
Keyword(s):  
Survival Analysis ◽  
Confidence Interval ◽  
Medium Term ◽  
Survival Analyses ◽  
Oxford Shoulder Score ◽  
The Mean ◽  
Shoulder Arthroplasties ◽  
Quick Dash ◽  
Shoulder Score

Background Shoulder resurfacings represent approximately one-third of shoulder arthroplasties and have the highest revision rates of any shoulder arthroplasty. We present a survival analysis of the Global CAP hemi-resurfacing implanted by multiple surgeons with up to 10 years of follow-up. Methods A life-table survival analysis of the Global CAP hemi-resurfacing was undertaken in a single site with multiple surgeons. Two survival analyses were performed; first, where failure was defined as component exchange and, second, where failure was defined as re-operation for any reason. Postoperative functional outcome was quantified using the Quick Disability Arm Hand and Shoulder Score (Quick DASH) and Oxford Shoulder Score (OSS). Results Eighty-seven Global CAPs were implanted in 75 patients. At a mean (SD) follow-up of 5.4 years (2.5 years) (range 0.9 years to 10 years), five patients had revision surgery and three patients underwent a reoperation for any reason. Survival at year 7 with component exchange as the endpoint was 80% (95% confidence interval = 93 to 65) and survival with re-operation for any reason as the end point was 62% (95% confidence interval = 82 to 50). The mean OSS and Quick DASH were 35 and 27.6, respectively. Conclusions The Global CAP has similar survivorship in the short to medium term and produces similar clinical outcomes compared to other shoulder resurfacings.

The outcome of antenatal ultrasound diagnosed anomalies of the kidney and urinary tract in a large Danish birth cohort

2016 ◽  
Vol 101 (9) ◽  
pp. 819-824 ◽  
Author(s):  
Liv Andrés-Jensen ◽  
Finn Stener Jørgensen ◽  
Jorgen Thorup ◽  
Julie Flachs ◽  
Jan Lysgaard Madsen ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Birth Cohort ◽  
University Hospital ◽  
Lower Probability ◽  
Threshold Values ◽  
Antenatal Ultrasound ◽  
Healthy Infants ◽  
Long Term Follow Up ◽  
Clinically Significant

ObjectiveAntenatal ultrasound diagnosed anomalies of the kidney and urinary tract (AUDAKUT) are reported in 0.3%–5% on prenatal ultrasound (US) and 0.3%–4.5% on postnatal US. The anterior-posterior diameter of the renal pelvis (APD) is an essential measurement. Series with low threshold values of APD prenatally and postnatally will include healthy infants. It is important to avoid follow-up of such infants.InterventionsIn 2006, new Danish guidelines for AUDAKUT were introduced.Aim of studyInvestigations of incidences and type of AUDAKUT based on Danish guidelines, including long-term follow-up.DesignCohort study.SettingCopenhagen University Hospital Hvidovre and Copenhagen University Hospital Rigshospitalet, Denmark.PatientsConsecutive cases with AUDAKUT in the second and third trimesters, which were either terminated before 22 completed weeks of gestation or born in the 8-year period January 2006–December 2013. Patients were followed until June 2014.Results50 193 live born children and 24 terminated fetuses (0.05%) were included. The prevalence of AUDAKUT was only 0.39% prenatally, 0.29% at first postnatal US and 0.22% at the end of follow-up, including terminated cases. The greater the prenatal and postnatal APD, the higher risk of febrile urinary tract infection (fUTI) and surgical intervention, and lower probability of resolution. 25% of the identified patients had fUTI and/or surgery.ConclusionsWe recommend threshold values of APD at least 10 mm in the third trimester and in general at least 12 mm at first postnatal US for intensive follow-up. In this largest to date unselected birth cohort of AUDAKUT, the incidences of clinically significant AUDAKUT were in the lowest range of those previously published.

scholarly journals Chew and spit (CHSP) in bariatric patients: a case series

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Phillip Aouad ◽  
Kristin Stedal ◽  
Gro Walø-Syversen ◽  
Phillipa Hay ◽  
Camilla Lindvall Dahlgren
Keyword(s):  
Bariatric Surgery ◽  
Weight Loss ◽  
Disordered Eating ◽  
Weight Loss Surgery ◽  
Eating Pathology ◽  
Post Surgery ◽  
Significant Depression ◽  
Bariatric Patients ◽  
Clinically Significant

Abstract Background Studies into the disordered eating behaviour of chew and spit have alluded to several cohorts more likely to engage in the behaviour, one such group being bariatric surgery candidates and patients. Weight-loss surgery candidates have received little to no attention regarding engaging in chew and spit behaviour. Changes in pre- and post- surgery eating pathology related to chew and spit behaviour has yet to be explored and described in academic literature. Case presentation The current study reports on three cases of individual women, aged 30, 35, and 62 respectively, who indicated engagement in chew and spit. All three cases underwent bariatric surgery (two underwent gastric bypass, one underwent vertical sleeve gastrectomy). Eating pathology—including chew and spit behaviour, anxiety and depression, and adherence to the Norwegian nutritional guidelines were examined pre-operatively and post-operatively (one and two-year follow-up). At baseline (pre-surgery), two participants reported that they engaged in chew and spit, compared to one patient post-surgery. All three cases reported that they, to at least some extent, adhered to dietary guidelines post-surgery. Subjective bingeing frequency appeared to be relatively low for all three cases, further declining in frequency at one-year follow-up. At baseline, one participant reported clinically significant depression and anxiety, with no clinically significant depression or anxiety reported at follow-ups in participants that chew and spit. Conclusions The current study provides a starting point for the exploration of chew and spit as a pathological symptom of disordered eating in bariatric patients. It highlights the need to further explore chew and spit before and after weight-loss surgery.

scholarly journals The association of late-life depression with all-cause and cardiovascular mortality among community-dwelling older adults: systematic review and meta-analysis

2019 ◽  
Vol 215 (2) ◽  
pp. 449-455 ◽  
Author(s):  
Jingkai Wei ◽  
Ruixue Hou ◽  
Xiaotao Zhang ◽  
Huiwen Xu ◽  
Liyang Xie ◽  
...  
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Cardiovascular Mortality ◽  
Meta Analysis ◽  
Late Life ◽  
Community Dwelling ◽  
Late Life Depression ◽  
Prospective Cohort Studies ◽  
Community Dwelling Older Adults

BackgroundLate-life depression has become an important public health problem. Available evidence suggests that late-life depression is associated with all-cause and cardiovascular mortality among older adults living in the community, although the associations have not been comprehensively reviewed and quantified.AimTo estimate the pooled association of late-life depression with all-cause and cardiovascular mortality among community-dwelling older adults.MethodWe conducted a systematic review and meta-analysis of prospective cohort studies that examine the associations of late-life depression with all-cause and cardiovascular mortality in community settings.ResultsA total of 61 prospective cohort studies from 53 cohorts with 198 589 participants were included in the systematic review and meta-analysis. A total of 49 cohorts reported all-cause mortality and 15 cohorts reported cardiovascular mortality. Late-life depression was associated with increased risk of all-cause (risk ratio 1.34; 95% CI 1.27, 1.42) and cardiovascular mortality (risk ratio 1.31; 95% CI 1.20, 1.43). There was heterogeneity in results across studies and the magnitude of associations differed by age, gender, study location, follow-up duration and methods used to assess depression. The associations existed in different subgroups by age, gender, regions of studies, follow-up periods and assessment methods of late-life depression.ConclusionLate-life depression is associated with higher risk of both all-cause and cardiovascular mortality among community-dwelling elderly people. Future studies need to test the effectiveness of preventing depression among older adults as a way of reducing mortality in this population. Optimal treatment of late-life depression and its impact on mortality require further investigation.Declaration of interestNone.

scholarly journals Neighborhood Resources Associated With Active Travel in Older Adults—A Cohort Study in Six European Countries

2020 ◽  
Vol 28 (6) ◽  
pp. 920-933
Author(s):  
Erja Portegijs ◽  
Erik J. Timmermans ◽  
Maria V. Castell ◽  
Elaine M. Dennison ◽  
Florian Herbolsheimer ◽  
...  
Keyword(s):  
Older Adults ◽  
Cohort Study ◽  
Confidence Interval ◽  
Travel Time ◽  
Public Transportation ◽  
Active Travel ◽  
European Countries ◽  
Response Options

Objectives: To study associations between perceived neighborhood resources and time spent by older adults in active travel. Methods: Respondents in six European countries, aged 65–85 years, reported on the perceived presence of neighborhood resources (parks, places to sit, public transportation, and facilities) with response options “a lot,” “some,” and “not at all.” Daily active travel time (total minutes of transport-related walking and cycling) was self-reported at the baseline (n = 2,695) and 12–18 months later (n = 2,189). Results: Reporting a lot of any of the separate resources (range B’s = 0.19–0.29) and some or a lot for all four resources (B = 0.22, 95% confidence interval [0.09, 0.35]) was associated with longer active travel time than reporting none or fewer resources. Associations remained over the follow-up, but the changes in travel time were similar, regardless of the neighborhood resources. Discussion: Perceiving multiple neighborhood resources may support older adults’ active travel. Potential interventions, for example, the provision of new resources or increasing awareness of existing resources, require further study.

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