Non-linear relationships in associations of depression and anxiety with alcohol use

2000 ◽  
Vol 30 (2) ◽  
pp. 421-432 ◽  
Author(s):  
B. RODGERS ◽  
A. E. KORTEN ◽  
A. F. JORM ◽  
P. A. JACOMB ◽  
H. CHRISTENSEN ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
General Population ◽  
Negative Affect ◽  
Anxiety Disorders ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Linear Relationships ◽  
Co Morbidity ◽  
Non Linear

Background. Many studies have demonstrated co-morbidity of alcohol abuse/dependence with mood and anxiety disorders but relatively little is known about anxiety and depression across the full continua of alcohol consumption and problems associated with drinking.Methods. Participants from a general population sample (N = 2725) aged 18–80 years completed the Alcohol Use Disorders Identification Test (AUDIT) and four measures of negative affect (two depression and two anxiety symptom scales) included in a self-completion questionnaire.Results. High consumption, AUDIT total score, and AUDIT problems score were associated with high negative affect scores in participants under 60 years old (ORs in the range 1·80–2·83). Graphical and statistical analyses using continuous measures of alcohol use/problems and negative affect identified non-linear relationships where abstainers and occasional drinkers, as well as heavy and problem drinkers, were at risk of high anxiety and depression levels. This pattern, however, was not found in those aged [ges ] 60 years. The U-shaped relationship was not an artefact of abstainers being typical of the general population in their distribution of negative affect.Conclusions. Studies of co-morbidity should acknowledge the possibility of non-linear associations and employ both continuous and discrete measures. Abstainers, as well as heavy drinkers, are at increased risk of symptoms of depression and anxiety disorders. Psychosocial factors may play a role in the U-shaped relationship between alcohol consumption and mortality.

scholarly journals Depression, Anxiety and Depression-anxiety comorbidity amid COVID-19 Pandemic: An online survey conducted during lockdown in Nepal

2020 ◽  
Author(s):  
Anil Sigdel ◽  
Anu Bista ◽  
Navaraj Bhattarai ◽  
Bimal Chandra Pun ◽  
Govind Giri ◽  
...  
Keyword(s):  
Mental Health ◽  
General Population ◽  
Online Survey ◽  
Risk Groups ◽  
Cross Sectional Study ◽  
Mental Wellbeing ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Cross Sectional ◽  
Co Morbidity

AbstractBackgroundLittle is known about the effect of the COVID-19 pandemic on mental health status during the lockdown period. Therefore, this study was conducted to assess prevalence of depression, anxiety and depression-anxiety comorbidity, and associated factors during the COVID-19 lockdown in Nepal.MethodsA quantitative cross-sectional study was conducted among the general population of Nepal. Data was collected from April 9 to April 16, 2020 using an e-questionnaire which was shared through different popular social media. A total of 349 participants were included. Self-reported depression and anxiety were assessed using the Patient Health Questionnaire and Generalized Anxiety tools respectively. Logistic regression analysis was conducted to identify the factors associated with depression, anxiety and depression and anxiety co-morbidity.ResultsThe prevalence rates of depression, anxiety and depression-anxiety co-morbidity were found to be 34.0%, 31.0% and 23.2% respectively. The multi-variate analysis showed that females, those living alone, health professionals and those who spent more time in accessing information about COVID-19 were significantly more likely to have depression, anxiety and depression-anxiety co-morbidity.ConclusionsHigh rates of depression and anxiety and co-morbidity were found to be prevailing among the general population during the COVID-19 pandemic lockdown in Nepal. The results suggest that only the scientific, but contextually appropriate messages about the disease should be disseminated to reduce unnecessary fears and anxiety. Awareness interventions to promote mental wellbeing need to be integrated into the response interventions. Community mental health care should be made accessible to at-risk groups.

scholarly journals Negative Affect, Alcohol Consumption, and Female-to-Male Intimate Partner Violence: A Daily Diary Investigation

Partner Abuse ◽  
2013 ◽  
Vol 4 (3) ◽  
pp. 332-355 ◽  
Author(s):  
Cory A. Crane ◽  
Christopher I. Eckhardt
Keyword(s):  
Intimate Partner Violence ◽  
Alcohol Consumption ◽  
Alcohol Use ◽  
Negative Affect ◽  
Partner Violence ◽  
Male Partner ◽  
Intimate Partner ◽  
College Age ◽  
The Status ◽  
Daily Risk

Although research suggests that both negative affect and alcohol use are related to the risk of intimate partner violence (IPV) in male samples, less is known about the status of these risk factors in female samples. Forty-three college-age females who reported a recent history of IPV perpetration submitted 6 weeks of Online daily reports pertaining to their levels of negative affect, alcohol consumption habits, and the occurrence of both male-to-female partner violence (MFPV) and female-to-male partner violence (FMPV). Results indicated that negative affect significantly predicted increases in the daily risk of FMPV. MFPV also significantly predicted FMPV risk. Alcohol consumption failed to predict FMPV perpetration on both levels of analysis. Results are discussed in terms of prevailing models of alcohol use, negative affect, and IPV.

scholarly journals Sex and Estrous Cycle Effects on Anxiety- and Depression-related Phenotypes in Two-hit Developmental Stress Model

2019 ◽  
Author(s):  
Ivana Jaric ◽  
Devin Rocks ◽  
Heining Cham ◽  
Alice Herchek ◽  
Marija Kundakovic
Keyword(s):  
Anxiety Disorders ◽  
Life Stress ◽  
Early Life ◽  
Early Life Stress ◽  
Anxiety And Depression ◽  
Synergistic Activity ◽  
Stress Model ◽  
Depression And Anxiety ◽  
Developmental Stress ◽  
Behavioral Phenotypes

Stress during sensitive developmental periods can adversely affect physical and psychological development and contribute to later-life mental disorders. In particular, adverse experiences during childhood dramatically increase the risk for the development of depression and anxiety disorders. Although women of reproductive age are twice as likely to develop anxiety and depression than men of the corresponding age, little is known about sex-specific factors that promote or protect against the development of psychopathology. To examine potential developmental mechanisms driving sex disparity in risk for anxiety and depression, we established a two-hit developmental stress model including maternal separation in early life followed by social isolation in adolescence. Our study shows complex interactions between early-life and adolescent stress, between stress and sex, and between stress and female estrogen status in shaping behavioral phenotypes of adult animals. In general, increased locomotor activity and body weight reduction were the only two phenotypes where two stressors showed synergistic activity. In terms of anxiety- and depression-related phenotypes, single exposure to early-life stress had the most significant impact and was female-specific. We show that early-life stress disrupts the protective role of estrogen in females, and promotes female vulnerability to anxiety- and depression-related phenotypes associated with the low-estrogenic state. We found plausible transcriptional and epigenetic alterations in psychiatric risk genes, Nr3c1 and Cacna1c, that likely contributed to the stress-induced behavioral effects. In addition, two general transcriptional regulators, Egr1 and Dnmt1, were found to be dysregulated in maternally-separated females and in animals exposed to both stressors, respectively, providing insights into possible transcriptional mechanisms that underlie behavioral phenotypes. Our findings provide a novel insight into developmental risk factors and biological mechanisms driving sex differences in depression and anxiety disorders, facilitating the search for more effective, sex-specific treatments for these disorders.

scholarly journals Psychological impact of COVID-19 pandemic on mental health of general population of Pakistan

2020 ◽  
Vol 9 (4) ◽  
pp. 256-261
Author(s):  
Muhammad Afzal ◽  
Dr. Hameed Mumtaz Durrani ◽  
Dr. Muhammad Imran Sohail
Keyword(s):  
Mental Health ◽  
General Population ◽  
Psychological Impact ◽  
Depression Score ◽  
Vulnerable Groups ◽  
Anxiety And Depression ◽  
P Value ◽  
Depression And Anxiety ◽  
Comorbid Disease ◽  
The Mean

Objective: To ascertain the psychological impact of COVID-19 pandemic on mental health of general population of Pakistan. Study design: Descriptive Cross-Sectional Study. Place and Duration of study: The participants in the study were selected from community population of Islamabad in a period of two months from 15th May to 15 July 2020. Patients and Methods: A total of 278 participants were selected for this study. All the participants were given structured questionnaire consisting on demographic information HADS scoring system to calculate depression and anxiety. HADS consists of 14 questions, each of which is scored 0–3. The possible scores for depression and anxiety ranged 0-21. Higher scores indicate increased severity of anxiety or depression. A cut off value of 8 or more was used to identify the anxiety and depression.  Results: The mean age was 33.42 ± 9.67 years and 148 (53.2%) were males. Among these participants 238 (85.6%) were resident of urban area, and 167 (60.1%) were married. Most of the participants were graduate 102 (36.7%). Thirty-six (12.9%) participants had a known patient of Covid-19 in their family or friends. Most of the participants 196 (70.5%) had no any comorbid disease. The mean anxiety score was noted to be 6.47 ± 5.51 and mean depression score was 6.65 ± 4.17. History of any comorbid disease showed a highly significant (p-value < 0.01) association with anxiety and depression score. Conclusion: To minimize the effect of Covid-19 pandemic on mental health of general population attention should be given to vulnerable groups like males, middle age adults, less educated and unemployed persons especially the people with chronic comorbid disease. Keywords: Covid-19, Mental health, General population, Anxiety, Depression

scholarly journals Prevalence of anxiety and depression among domestic and foreign medical students in Poland

2020 ◽  
Author(s):  
Aneta Anna Jaroszewska ◽  
Szymon Tyras ◽  
Martyna Dziewit ◽  
Joanna Jaroszewska ◽  
Katarzyna Podhorodecka
Keyword(s):  
Medical Student ◽  
Medical Students ◽  
Anxiety Disorders ◽  
Study Groups ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Student Group ◽  
Significant Difference ◽  
Prevalence Of Depression ◽  
Depression Disorders

Introduction: Depression and anxiety disorders are much more common among medical students than in the general population. Due to additional risk factors, foreign students may be particularly vulnerable. Despite this, there is still an insufficient number of studies analyzing the prevalence of mental disorders among foreign medical students, especially in Poland. Aim: The aim of the study was to assess and compare the prevalence of anxiety and depression disorders between domestic and foreign medical students in Poland. Material and methods: An anonymous internet survey containing questions about socio-demography and the Hospital Anxiety and Depression Scale questionnaire was distributed among students. Based on the field of study and country of origin, participants were divided into 3 groups – Polish medical student group (PMG, n = 214); foreign medical student group (FMG, n = 59) and control group, which were Polish students of other faculties (CG, n = 476). The study groups were compared using the χ2 test. Results and discussion: The prevalence of depression disorders was 30%, 31% and 28% (PMG, FMG and CG, respectively). No statistically significant difference was observed between the study groups (P = 0.77). The prevalence of anxiety disorders was 57%, 90% and 59% (PMG, FMG and CG, respectively). Anxiety disorders were more common among FMG as compared to PMG and CG (P < 0.01 in both cases). Conclusions: The prevalence of depression and anxiety among medical students in Poland is high. Foreign medical students appear to be particularly vulnerable to anxiety disorders.

scholarly journals The impact of relaxed traveller allowances

2018 ◽  
Vol 35 (4) ◽  
pp. 275-287
Author(s):  
Martin Stafström
Keyword(s):  
Panel Data ◽  
Alcohol Consumption ◽  
Alcohol Use ◽  
General Population ◽  
Fixed Effects ◽  
Alcoholic Beverages ◽  
Heavy Alcohol ◽  
Private Person ◽  
Cross Border ◽  
Heavy Alcohol Use

Aim: To analyse to what extent the gradual relaxation of traveller allowances for alcoholic beverages 2001–2004 changed consumer behaviours and subsequent alcohol consumption patterns within a longitudinal panel data population study in Southern Sweden. Methods: General population random sample panel data study with repeated measurements were collected in 1999, in 2005, and in 2010 in the county of Scania. The study analyses answers from 9770 individuals, who in 1999 were 18–80 years old. A fixed-effects modelling was applied to assess the association between consumer behaviour and change in alcohol use across the study period. Results: Cross-border shopping for alcoholic beverages was associated, on average, with a 3.1% ( p < 0.001) increase in alcohol use. Buying imported alcohol from a private person was associated with a mean increase of 2.6% ( p < 0.001), with a total additive effect of 5.7%. Furthermore, when stratified for gender, age, and location, significant fixed effects were found. The magnitude was greater among women, younger and older ages, and in particular in the Northeast and Central regions. Both consumer behaviours – cross-border trading ( OR 1.6, CI 95% 1.28–1.92) and buying alcohol from a private person ( OR 1.4, CI 95% 1.12–1.73) – were significantly associated with heavy alcohol use. Conclusion: The fixed-effects analyses identified significant associations between consumer behaviours and alcohol consumption. The uptake of behaviours that developed because of a relaxation of the Swedish alcohol policy has contributed to an overall long-term increase in alcohol use and higher prevalence of heavy alcohol use within this general population study sample.

Prodromes of Depression and Anxiety

1989 ◽  
Vol 155 (4) ◽  
pp. 490-495 ◽  
Author(s):  
Jane M. Murphy ◽  
Arthur M. Sobol ◽  
Donald C. Olivier ◽  
Richard R. Monson ◽  
Alexander H. Leighton ◽  
...  
Keyword(s):  
General Population ◽  
Anxiety Disorders ◽  
Psychiatric Epidemiology ◽  
Depression And Anxiety ◽  
Longitudinal Investigation ◽  
Incident Cases ◽  
Premonitory Symptoms

A longitudinal investigation of psychiatric epidemiology in a general population (the Stirling County study) has indicated that the incidence of depression and anxiety disorders is low relative to prevalence, because these disorders have long durations. In an average year approximately nine adults among 1000 experience a first-ever episode of one of these disorders. Incident cases over the course of a 16-year follow-up were more likely to have had premonitory symptoms than to have been asymptomatic at the beginning of the study. Among the relatively small number of people who exhibited the clearest prodromal manifestations, incidence was 20 per 1000 annually. It might be possible to intervene before such disorders become fully formed and persistent if the precursors are given attention.

scholarly journals Alcohol Use Disorder Is Differently Associated With Psychotic Symptoms According To Underlying Psychiatric Disorders: A General Population Study

2019 ◽  
Author(s):  
Baptiste Pignon ◽  
Guillaume Sescousse ◽  
Ali Amad ◽  
Imane Benradia ◽  
Guillaume Vaiva ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
General Population ◽  
Anxiety Disorders ◽  
Psychiatric Disorders ◽  
Alcohol Use Disorder ◽  
Psychotic Disorders ◽  
Auditory Hallucinations ◽  
Psychotic Symptoms ◽  
Depression And Anxiety ◽  
General Population Study

Abstract Aims Psychotic symptoms can occur in the general population, and alcohol use disorder (AUD) is an identified vulnerability factor. However, it remains unclear how AUD is associated with psychotic symptoms, depending on the underlying psychiatric condition. We aimed to compare the prevalence of psychotic symptoms among subjects with different types of psychiatric disorders, i.e. unipolar or bipolar disorders, anxiety disorders, psychotic disorders or no psychiatric disorder, depending on whether or not there was an underlying AUD. Methods In a 38,694-subject general population study, we compared the likelihood of occurrence of seven types of psychotic symptoms, depending on the AUD status and the underlying psychiatric disorders, after adjustment for age, sex, marital status, education and income levels. Results In unipolar depression and anxiety disorders, almost all types of psychotic symptoms were found associated with AUD (odds ratios (ORs) between 1.98 and 2.19). In contrast, in bipolar disorder, only auditory hallucinations were associated with AUD (OR = 2.50). In psychotic disorders, only thought broadcasting was more frequent among subjects with AUD (OR = 1.78). Conclusion Our findings in depression and anxiety disorders are in line with the ‘dual diagnosis’ concept, which posits that comorbid psychiatric/addictive disorders form distinctive entities that are more frequently associated with non-specific severity factors, here psychotic symptoms. The co-occurrence of AUD in bipolar/psychotic disorders was not associated with a generalized increased occurrence of psychotic symptoms but altered their manifestations with an increased risk of auditory hallucinations for bipolar disorder and thought broadcasting for psychotic disorders.

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