scholarly journals Scedosporium Cerebral Abscesses After Extra-Corporeal Membrane Oxygenation

2010 ◽  
Vol 37 (5) ◽  
pp. 671-676 ◽  
Author(s):  
Hosam Al-Jehani ◽  
Marie-Christine Guiot ◽  
Carlos Torres ◽  
Judith Marcoux
Keyword(s):  
Immunocompetent Patient ◽  
Community Acquired Pneumonia ◽  
Scedosporium Apiospermum ◽  
Surgical Interventions ◽  
Therapeutic Challenge ◽  
Membrane Oxygenation ◽  
High Clinical Suspicion ◽  
The Central Nervous System ◽  
Brain Abscesses ◽  
Cerebral Infection

Background:Scedosporial infections are usually encountered in the immunocompromised patients. However, they are now emerging in the immunocompetent population and have an affinity for the central nervous system. They represent a therapeutic challenge, since they are highly resistant to most antifungal medications.Methods:We report the case of an immunocompetent patient with multiple cerebral abscesses secondary to Scedosporium apiospermum following extracorporeal membrane oxygenation (ECMO) and review the literature about this challenging cerebral infection.Results:A previously healthy 33-year-old male admitted to the hospital for a community-acquired pneumonia requiring ECMO subsequently developed multiple cerebral abscesses. He was empirically treated with caspofungin, which was changed to voriconazole once surgical aspiration revealed Scedosporium apiospermum. Despite multiple aspirations, decompressive craniectomy to alleviate intracranial pressure, and an appropriate antifungal agent, the patient did not survive this aggressive infection.Conclusion:Brain abscesses with Scedosporium apiospermum present a therapeutic challenge. High clinical suspicion leading to early appropriate antifungal therapy and combined surgical interventions might improve the prognosis.

A Rare Case of Tuberculous Prostatitis

2016 ◽  
Vol 1 (2) ◽  
pp. 33
Author(s):  
Nurul Yaqeen Mohd Esa ◽  
Mohammad Hanafiah ◽  
Marymol Koshy ◽  
Hilmi Abdullah ◽  
Ahmad Izuanuddin Ismail ◽  
...  
Keyword(s):  
Rare Case ◽  
Correct Diagnosis ◽  
Immunocompetent Patient ◽  
Clinical Suspicion ◽  
Tuberculosis Infection ◽  
Advanced Age ◽  
Immunocompromised Patients ◽  
Prostatic Biopsy ◽  
High Clinical Suspicion

Tuberculous prostatitis is an uncommon form of tuberculosis infection. It is commonly seen in immunocompromised patients and in those of middle or advanced age. The diagnosis is often not straight forward due to the nature of its presentation. We report a case of tuberculous prostatitis in a young, healthy and immunocompetent patient, who initially presented with respiratory features, followed by episodes of seizures and testicular swelling. He was finally diagnosed with tuberculous prostatitis after prostatic biopsy. This case illustrates that in a high TB prevalence environment, when symptoms warrant, there should be a high clinical suspicion coupled with a thorough approach in order to arrive at a correct diagnosis of TB prostatitis.

SURGERY IN A HEMOPHILIAC CHILD WITH INTRACRANIAL HEMORRHAGE

PEDIATRICS ◽  
1961 ◽  
Vol 28 (5) ◽  
pp. 800-804
Author(s):  
John H. Fuerth ◽  
Paul Teng ◽  
Erwin Goldenberg
Keyword(s):  
Los Angeles ◽  
Type A ◽  
Bleeding Tendency ◽  
Laboratory Findings ◽  
Excessive Bleeding ◽  
Surgical Interventions ◽  
Fatal Hemorrhage ◽  
History Of ◽  
System 2 ◽  
The Central Nervous System

THE UNUSUAL bleeding tendency in hemophiliacs has been known since biblical times, and its hazards have been recognized in even such simple surgical procedures as circumcision.1 Perhaps the most dangerous complication of hemophilia is bleeding into the central nervous system.2 It therefore seems worthwhile to report the case of a 2-year-old hemophiliac who survived several intracranial hemorrhages, with two surgical interventions, but who 4 months later had a fourth and fatal hemorrhage. CASE REPORT History D. H. was a 2-year-old hemophiliac with numerous admissions to the Kaiser Foundation Hospital, Los Angeles, for bleeding episodes. He was born at another hospital, was circumcised shortly after birth and had excessive bleeding following this. His first admission was at the age of 1 year for bleeding following a tongue bite. At that time he had an abnormal result of a prothrombin consumption test, with 55% residual prothrombin in the serum. The prothrombin consumption was corrected by fresh normal plasma and barium sulfate adsorbed plasma, but not by serum or plasma from a known hemophiliac type A. The diagnosis of hemophilia type A was thus established. He had two brothers who were investigated and found to be normal. There was no abnormal bleeding tendency on his father's side, but two uncles of his mother and two first cousins were said to be "bleeders." No further details were known. Physical and Laboratory Findings The boy was admitted to the hospital on the evening of October 13, 1957, with a history of vomiting and progressive lethargy of 2 days' duration.

Multiple cortical brain abscesses due toListeria monocytogenesin an immunocompetent patient

2017 ◽  
Vol 48 (2) ◽  
pp. 160-163 ◽  
Author(s):  
Sadia Khan ◽  
Anil Kumar ◽  
Satyajit Kale ◽  
Nitin Kurkure ◽  
Gulsiv Nair ◽  
...  
Keyword(s):  
Immunocompetent Patient ◽  
Brain Abscesses

scholarly journals Photo Quiz: Frontal Brain Abscesses in an Immunocompetent Patient

2016 ◽  
Vol 54 (9) ◽  
pp. 2215-2215
Author(s):  
James Walter Snyder ◽  
Bradley Gibson
Keyword(s):  
Immunocompetent Patient ◽  
Frontal Brain ◽  
Brain Abscesses

scholarly journals Case Report of Disseminated Pseudomonas Infection with Superadded Burkholderia Infection - A Battle Lost!

2021 ◽  
Vol 6 (06) ◽  
pp. 393-397
Author(s):  
Dr Sangita Kamath ◽  
Dr Murari Bharadwaj ◽  
Dr Manish Kumar ◽  
Dr Ashok Sunder
Keyword(s):  
Risk Factors ◽  
Burkholderia Cepacia ◽  
Case Reports ◽  
Immunocompetent Patient ◽  
Community Acquired Pneumonia ◽  
Healthy Individuals ◽  
Nosocomial Pathogen ◽  
Gram Negative ◽  
Pseudomonas Infection ◽  
Progressive Course

Pseudomonas aeruginosa is a gram-negative pathogen, that often causes nosocomial pneumonia in hospitalized patients. Most of these patients have risk factors for pseudomonas infection. Although uncommon, there have been case reports of previously healthy individuals who developed community-acquired pneumonia (CAP) caused by P. aeruginosa. Such cases have often rapidly progressive course and prove fatal. We, hereby, report a case of pseudomonas pneumonia in a 29-year old immunocompetent patient, who developed disseminated infection and superinfection with yet another nosocomial pathogen, Burkholderia cepacia, eventually leading to septic shock and death, despite appropriate antibiotic therapy.

Coccidioidomycosis

2010 ◽  
pp. 1020-1023
Author(s):  
Gregory M. Anstead ◽  
John R. Graybill
Keyword(s):  
Central Nervous System ◽  
United States Of America ◽  
Primary Infection ◽  
Soft Tissues ◽  
Community Acquired Pneumonia ◽  
Immunocompromised Patients ◽  
System Diagnosis ◽  
The Central Nervous System ◽  
Disseminated Disease ◽  
In Pregnancy

Coccidioidomycosis results from inhalation of arthroconidia of Coccidioides spp., which are soil fungi endemic to the south-western United States of America and parts of Latin America. Most infections are asymptomatic, but primary infection may resemble community-acquired pneumonia, sometimes with hypersensitivity manifestations such as erythema nodosum, erythema multiforme, and arthritis. Acute pulmonary infection usually resolves spontaneously, but—especially in immunocompromised patients, African Americans, and Filipinos—it may progress to persistent pulmonary disease or disseminate to skin, soft tissues, the osteoarticular system, and the central nervous system. Diagnosis is by culture, histopathology or serology. Fluconazole and itraconazole are usually the initial drugs of choice, with amphotericin B reserved for severe pulmonary and disseminated disease, and in pregnancy. In refractory cases, posaconazole and voriconazole are alternative antifungal agents....

Scedosporium Apiospermum: Rare Cause of Brain Abscess in an Immunocompetent Patient

2020 ◽  
Vol 68 (4) ◽  
pp. 906
Author(s):  
ChandrashekharE Deopujari ◽  
AmolY Sudke ◽  
SalmanT Shaikh ◽  
AsmitaS Sakle
Keyword(s):  
Brain Abscess ◽  
Immunocompetent Patient ◽  
Scedosporium Apiospermum

scholarly journals Aspergillosis of the central nervous system

1996 ◽  
Vol 114 (5) ◽  
pp. 1274-1277 ◽  
Author(s):  
Valdir Golin ◽  
Sandra Regina Schwarzwalder Sprovieri ◽  
José Eduardo Delfini Cançado ◽  
Jefferson Walter Daniel ◽  
Lycia Maria Jenné Mimica
Keyword(s):  
Unusual Case ◽  
Parietal Lobe ◽  
Fungus Ball ◽  
Intracranial Abscess ◽  
Radiological Images ◽  
The Central Nervous System ◽  
Brain Abscesses ◽  
Initiation Of Therapy ◽  
Anti Fungal ◽  
The Brain

The authors report an unusual case involving a 38 year-old man who developed a intracranial abscess caused by Aspergillus of the parietal lobe. Cerebral aspergilloma of an initial pulmonary origin developed in a patient with "Fungus Ball" secondary to tuberculosis sequelae. The diagnosis was made through the isolation of Aspergillus from the secretion of the brain abscesses. The patient was treated with drainage of the abscesses and Amphotericin B. He presented a progressive regression of the radiological images (brain and pulmonary) over a period of 55 days. This report emphasizes the importance of combined anti-fungal therapy and surgical resection as a treatment for cerebral aspergilloma. Furthermore, an early initiation of therapy should improve the prognosis in such cases.

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