Portugal and Angola: similarities and differences inToxoplasma gondiiseroprevalence and risk factors in pregnant women

SUMMARYIn this study we determined the presence of IgM/IgG antibodies toToxoplasma gondiiin sera of 155 and 300 pregnant women from Lisbon (Portugal) and Luanda (Angola), respectively, and evaluated the potential risk factors associated with this infection. DNA detection was performed by PCR assays targetingT. gondiiregions (RE/B1). Overall, 21·9% (10·9% IgG, 10·9% IgG/IgM) of the Lisbon women and 27·3% (23·7%, IgG, 2% IgM, 1·7% IgG/IgM) of the Luanda women had antibodies toT. gondii. Single variable and binary logistic regression analyses were conducted. Based on the latter, contacts with cats (family/friends), and having more than two births were identified as risk factors forToxoplasmainfection in Lisbon women. In Luanda, the risk factors forT. gondiiinfection suggested by the single variable analysis (outdoor contact with cats and consumption of pasteurized milk/dairy products) were not confirmed by binary logistic regression. This study shows original data from Angola, and updated data from Portugal in the study of infection byT. gondiiin pregnant women, indicating that the prevalence of anti-Toxoplasmaantibodies is high enough to alert the government health authorities and implement appropriate measures to control this infection.

Download Full-text

Seroprevalence and Risk Factors of Toxoplasmosis in Togo

European Scientific Journal ESJ ◽

10.19044/esj.2018.v14n33p56 ◽

2018 ◽

Vol 14 (33) ◽

pp. 56 ◽

Cited By ~ 1

Author(s):

Amivi Tété-Bénissan ◽

Mlatovi Dégbé ◽

Holoud Maman ◽

Abiba K. Banla ◽

Agnon Balogou ◽

...

Keyword(s):

Risk Factors ◽

Toxoplasma Gondii ◽

Pregnant Women ◽

Parasitic Infection ◽

Elisa Method ◽

Health Authorities ◽

Potential Risk Factors ◽

Risks Factors ◽

Young Subjects ◽

Undercooked Meat

Objectives: Toxoplasmosis is caused by Toxoplasma gondii. 50 to 70% of African are contaminated and 60% to 80% in Togo. This parasitic infection involves disorders in immunocompromised persons and pregnant women. The purpose of this study is to evaluate the seroprevalence of toxoplasmosis and the risk factors of contamination in the Togolese population. Methods: Prospective studies from January 2012 to December 2015 concerned 7076 patients. A survey on the risk factors for Toxoplasma gondii contamination has done. The seroprevalence was monitored by examining serological antibodies IgG and IgM using ELISA method. Sampling of 200 excreta of domestic cats were analyzed by coproscopy examinations Results: The average age was 32.61±6.80 years old. The seroprevalence of IgM was 2.85%; and for IgG 59.7%. IgG were high in men (67.0% vs. 58.6%, p<0.0001); IgM were high in women (2.81% vs. 1.85%, p<0.01). In this study, we observed 57.49% immunized subjects. Regarding potential risk factors for contamination, the survey revealed that 80.5% of subjects consume raw garden produce, 65.4% non-potable and 8.3% undercooked meat. In cats, 20.5% of them excreted oocysts of Toxoplasma gondii. Conclusion: The prevalence of the toxoplasmosis was high in the Togolese population because the risks factors were variable and the level of contamination were high too. The country’s health authorities, especially for the pregnant women, should install sensitization and prevention programs on the risks of the contamination of toxoplasmosis. The high proportion of the young subjects affected constitutes a socio-economical danger for the country.

Download Full-text

Risk factors of recurrence after endovascular embolization of posterior communicating artery aneurysms

Interventional Neuroradiology ◽

10.1177/15910199211054715 ◽

2021 ◽

pp. 159101992110547

Author(s):

Degang Wu ◽

Bin Sheng ◽

Xinggen Fang ◽

Zhenbao Li

Keyword(s):

Risk Factors ◽

Logistic Regression ◽

Packing Density ◽

Coil Embolization ◽

Binary Logistic Regression ◽

Endovascular Embolization ◽

Saccular Aneurysm ◽

Posterior Communicating Artery ◽

Binary Logistic Regression Analysis ◽

Potential Risk Factors

Background and objective To determine the risk factors for recurrence after endovascular embolization of posterior communicating artery aneurysms (PcomA). Methods We retrospectively analyzed a cohort of 163 patients harboring 172 PocmAs who were treated with endovascular embolization from January 2019 to December 2020. The patients were divided into recurrence and stable groups depending on outcome. Univariate and logistic regression analyses were performed to determine the potential risk factors of recurrence during follow-up. Results Of the total 163 patients harboring 172 aneurysms, 107 were treated with simple coil occlusion and 65 were treated with stent-assisted coil embolization. There were significant differences in aneurysm sizes and use of non-stent-assisted coil embolizations between the groups (P < 0.05). The incidence of saccular aneurysm and Raymond grade were significantly higher in the recurrent group than in the stable group (P < 0.01). After variable selection, Raymond grade, aneurysm size, saccular aneurysm and non-stent-assisted coil embolization were included in further analysis. Binary logistic regression analysis revealed significant associations with non-stent-assisted coil embolization (P = 0.007), packing density (P < 0.001) and Raymond grades II (P < 0.001) and III (P = 0.002). Conclusion Non-stent-assisted coil embolization, as well as packing density and Raymond grades II grade III are associated with recurrence after endovascular treatment of PcomA.

Download Full-text

The Factors Associated with the Fatal Outcome of Stroke

Serbian Journal of Experimental and Clinical Research ◽

10.2478/sjecr-2019-0014 ◽

2019 ◽

Vol 0 (0) ◽

Author(s):

Andjela Milojevic Samanovic ◽

Dragan Milovanovic ◽

Vladimir Gajic ◽

Aleksandar Raskovic ◽

Dragan Milojevic

Keyword(s):

Risk Factors ◽

Logistic Regression ◽

Fatal Outcome ◽

Case Series ◽

Binary Logistic Regression ◽

Factors Associated ◽

Clinical Center ◽

Neurology Clinic ◽

Potential Risk Factors ◽

Severity Of The Disease

Abstract The aim of this study is to determine the risk factors associated with the fatal outcome of stroke. The research was designed as observational, non-interventional study, conducted by the type of case series, and it included 290 patients hospitalized with a diagnosis of stroke at Neurology Clinic of the Clinical Center Kragujevac during the observed period from 01/02/2013 to 31/01/2014. The data used for the research were: documentation of Neurology Clinic of the Clinical Center Kragujevac, documentation of the Institute of Public Health Kragujevac and patients’ questionnaires. The results of univariate binary logistic regression pointed out a relevant connection between the fatal outcome of stroke and age (p˂ 0.0001), gender (p˂ 0.0001), the severity of the disease (p = 0.002), smoking (p = 0.021), care for the parents’ health (p = 0.018), the concern about business problems (p = 0.018), while the influence of antidepressants was indicative (p = 0.066), whereas using the multivariate binary logistic regression, it was concluded that age (OR=1.096; 95% CI=1.059-1.134; p<0.001), the severity of the disease (OR=4.324; 95% CI=1.256-14.885; p=0.020) and the use of antidepressants (OR=5.578; 95% CI=1.178-26.423; p=0.030) were factors independently associated with the mortality rate. These findings suggest that it would be useful to carry out additional comprehensive research about all potential risk factors for the occurrence of stroke, and also to establish all the steps that can be taken in order to identify and detect risk factors, their elimination or reduction, and, accordingly, to take aggressive measures of primary and secondary prevention.

Download Full-text

Influenza vaccination during pregnancy and influencing factors in Korea: A multicenter questionnaire study of pregnant women and obstetrics and gynecology doctors

BMC Pregnancy and Childbirth ◽

10.1186/s12884-021-03984-2 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Byung Soo Kang ◽

San Ha Lee ◽

Woo Jeng Kim ◽

Jeong Ha Wie ◽

In Yang Park ◽

...

Keyword(s):

Influenza Vaccination ◽

Pregnant Women ◽

Influencing Factors ◽

World Health ◽

Obstetrics And Gynecology ◽

Health Authorities ◽

The Government ◽

Vaccine Information ◽

Health Organization ◽

Maternal Influenza

Abstract Background Although the World Health Organization and health authorities in most countries recommend that pregnant women receive inactivated influenza virus vaccines, coverage remains low. This study aimed to investigate (1) the proportion of pregnant women who received an influenza vaccination and influencing factors and (2) the proportion of obstetrics and gynecology (OBGYN) doctors who routinely recommend influenza vaccination to pregnant women and influencing factors. Methods Two separate, anonymized questionnaires were developed for physicians and pregnant and postpartum women and were distributed to multicenters and clinics in South Korea. The proportions of women who received influenza vaccination during pregnancy and OBGYN doctors who routinely recommend the influenza vaccine to pregnant women were analyzed. Independent influencing factors for both maternal influenza vaccination and OBGYN doctors’ routine recommendations to pregnant women were analyzed using log-binomial regression analysis. Results The proportion of self-reported influenza vaccination during pregnancy among 522 women was 63.2%. Pregnancy-related independent factors influencing maternal influenza vaccination were “(ever) received information about influenza vaccination during pregnancy” (OR 8.9, 95% CI 4.17–19.01), “received vaccine information about from OBGYN doctors” (OR 11.44, 95% CI 5.46–24.00), “information obtained from other sources” (OR 4.38, 95% CI 2.01–9.55), and “second/third trimester” (OR 2.41, 95% CI 1.21–4.82).. Among 372 OBGYN doctors, 76.9% routinely recommended vaccination for pregnant women. Independent factors effecting routine recommendation were “working at a private clinic or hospital” (OR 5.33, 95% CI 2.44–11.65), “awareness of KCDC guidelines” (OR 3.11, 95% CI 1.11–8.73), and “awareness of the 2019 national free influenza vaccination program for pregnant women” (OR 4.88, 95% CI 2.34–10.17). OBGYN doctors most commonly chose ‘guidelines proposed by the government or public health (108, 46%) and academic committees (59, 25%), as a factor which expect to affect the future recommendation Conclusion This study showed that providing information about maternal influenza vaccination, especially by OBGYN doctors, is crucial for increasing vaccination coverage in pregnant women. Closer cooperation between the government and OBGYN academic societies to educate OBGYN doctors might enhance routine recommendations.

Download Full-text

Abstract P249: Incident Sleep-Disordered Breathing is Associated with Obesity: Penn State Child Cohort

Circulation ◽

10.1161/circ.127.suppl_12.ap249 ◽

2013 ◽

Vol 127 (suppl_12) ◽

Author(s):

Edward O Bixler ◽

Alexandros N Vgontzas ◽

Duanping Liao ◽

Susan Calhoun ◽

Julio Fernandez-Mendoza ◽

...

Keyword(s):

Risk Factors ◽

Logistic Regression ◽

Sleep Disordered Breathing ◽

Population Sample ◽

Population Based ◽

Penn State ◽

Potential Risk Factors ◽

State Child ◽

Disordered Breathing

Objectives: To study the epidemiology of sleep-disordered breathing (SDB) in adolescents, which has received little attention. Methods: The Penn State Child Cohort (PSCC) is a representative general population sample of 700 children aged 5-12 years. Our preliminary results are based on an average 8 year follow up of the initial 300 prospective subjects (~43%) from this ongoing cohort study. A logistic regression was used to assess the association between potential risk factors and incident SDB. Results: The mean age at the 8-year follow up examination was 17.2 ± 0.1 years, with an average BMI percentile of 66.6 ± 1.6 and 56.5% boys. At baseline 1.5% of this subsample had SDB, defined by Apnea Hypopnia Index (AHI > 5 /hour). Surprisingly, there was no persistence of SDB. Eight-year incident SDB was 10.5%. The average AHI in those with incident SDB was 12.7 with a maximum of 92.4. Incident SDB was similar for girls (7.8%) and boys (12.7%). Those with SDB were older than those without (18.7 vs 17.0 years, P<0.001) and girls with SDB were older than boys with SDB (20.0 vs 18.0 years, P=0.002). Those with incident SDB tended to have a greater change in BMI percentile (8.2 vs 1.8, P = 0.143) during the follow up and slightly higher minority representation (25.8% vs 21.9%, P=0.655). A logistic regression model identified three variables that were associated with incident SDB, controlling for baseline AHI: age (OR = 1.5 (1.3, 1.9) P<0.001), male (OR= 2.5 (1.11,10.00) P=0.021), and [[Unable to Display Character: ∆]]BMIPCT (OR=1.2(1.02, 1.5) P=0.032). Conclusion: In this population based sample of adolescents, the 8-year incidence of SDB was high (10.5%), whereas childhood SDB did not persist into adolescence. Further, the results indicate that risk factors for incident SDB in adolescents are age, male and the development of obesity.

Download Full-text

Horse-related incidents and factors for predicting injuries to the head

BMJ Open Sport & Exercise Medicine ◽

10.1136/bmjsem-2018-000398 ◽

2018 ◽

Vol 4 (1) ◽

pp. e000398 ◽

Cited By ~ 7

Author(s):

Lauren Meredith ◽

Robert Ekman ◽

Robert Thomson

Keyword(s):

Risk Factors ◽

Logistic Regression ◽

Head Injury ◽

Soft Tissue ◽

Head Injuries ◽

Binary Logistic Regression ◽

Soft Tissue Injuries ◽

Dental Services ◽

Incident Type ◽

Local Healthcare

ObjectivesHead injuries are the leading cause of death in horse-related injury events and, even since the introduction of helmets, represent a sizeable proportion of all horse-related injuries. Falls from horseback and kicks to the head are the most frequent type of incident causing head injuries, but it is unknown whether these incidents are predictors of head injury. This study aimed to investigate head injuries and the association between incident type and head injury.MethodRetrospective review of 7815 horse-related injury events was conducted. Data were gathered from hospitals, local healthcare centres and public dental services in Skaraborg, Sweden. Binary logistic regression was used to analyse the association between the incident type and occurrence of head injury while controlling for risk factors.ResultsApproximately 20% of riders sustained a head injury, mostly soft tissue injuries (56.3%) and concussions (33.4%). A fall from or with the horse was the primary cause of head injury (63.9%). Those who fell from a carriage or other height or who were injured through contact with the horse had no difference in the likelihood of head injury when compared with those that fell from or with the horse. However, those who sustained an injury without any horse contact had lower odd of head injury (OR: 0.640, p<0.00005, 95% CI 0.497 to 0.734). Additionally, the older the rider, the lower the odds of head injury (OR=0.989, p<0.00005, 95% CI 0.985 to 0.993).ConclusionImproved protection for those suffering falls from horseback as well as those who are kicked in the head should be investigated.

Download Full-text

Clinical Significance of CYFRA21-1, AFP, CA-153, CEA, and CA-199 in the Diagnosis of Lung Cancer Ocular Metastasis in Hypertension Population

Frontiers in Cardiovascular Medicine ◽

10.3389/fcvm.2021.670594 ◽

2021 ◽

Vol 8 ◽

Author(s):

Jing Tang ◽

Qian-Min Ge ◽

Rong Huang ◽

Hui-Ye Shu ◽

Ting Su ◽

...

Keyword(s):

Risk Factors ◽

Lung Cancer ◽

Logistic Regression ◽

Sensitivity And Specificity ◽

Cancer Metastasis ◽

Binary Logistic Regression ◽

Diagnostic Value ◽

Ca 125 ◽

Pathological Type ◽

Independent Risk Factors

Purpose: To detect lung metastases, we conducted a retrospective study to improve patient prognosis.Methods: Hypertension patients with ocular metastases (OM group; n = 58) and without metastases (NM group; n = 1,217) were selected from individuals with lung cancer admitted to our hospital from April 2005 to October 2019. The clinical characteristics were compared by Student's t-test and chi-square test. Independent risk factors were identified by binary logistic regression, and their diagnostic value evaluated by receiver operating characteristic curve analysis.Results: Age and sex did not differ significantly between OM and NM groups; There were significant differences in pathological type and treatment. Adenocarcinoma was the main pathological type in the OM group (67.24%), while squamous cell carcinoma was the largest proportion (46.43%) in the NM group, followed by adenocarcinoma (34.10%). The OM group were treated with chemotherapy (55.17%), while the NM group received both chemotherapy (39.93%) and surgical treatment (37.06%). Significant differences were detected in the concentrations of cancer antigen (CA)−125, CA-199, CA-153, alpha fetoprotein (AFP), carcinoembryonic antigen (CEA), cytokeratin fraction 21-1 (CYFRA21-1), total prostate-specific antigen, alkaline phosphatase, and hemoglobin (Student's t-test). Binary logistic regression analysis indicated that CA-199, CA-153, AFP, CEA, and CYRFA21-1 were independent risk factors for lung cancer metastasis. AFP (98.3%) and CEA (89.3%) exhibited the highest sensitivity and specificity, respectively, while CYRFA21-1 had the highest area under the ROC curve value (0.875), with sensitivity and specificity values of 77.6 and 87.0%, respectively. Hence, CYFRA21-1 had the best diagnostic value.

Download Full-text

Retrospective analysis of risk factors of hypotensive bradycardic events during shoulder arthroscopic surgery under interscalene blockade in the sitting position

Korean Journal of Anesthesiology ◽

10.4097/kja.20035 ◽

2020 ◽

Vol 73 (6) ◽

pp. 542-549

Author(s):

Taeha Ryu ◽

Baek Jin Kim ◽

Seong Jun Woo ◽

So Young Lee ◽

Jung A Lim ◽

...

Keyword(s):

Risk Factors ◽

Logistic Regression ◽

Odds Ratio ◽

Arthroscopic Surgery ◽

Sitting Position ◽

Past Medical History ◽

Frequent Adverse Event ◽

Increased Risk ◽

Potential Risk Factors ◽

Independent Risk Factors

Background: Hypotensive bradycardic events (HBEs) are a frequent adverse event in patients who underwent shoulder arthroscopic surgery under interscalene block (ISB) in the sitting position. This retrospective study was conducted to investigate the independent risk factors of HBEs in shoulder arthroscopic surgery under ISB in the sitting position. Methods: A total of 2549 patients who underwent shoulder arthroscopic surgery under ISB and had complete clinical data were included in the study. The 357 patients who developed HBEs were included in the HBEs group, and the remaining 2192 in the non-HBEs group. The potential risk factors for HBEs, such as age, sex, past medical history, anesthetic characteristics, and intraoperative medications were collected and compared between the groups. Statistically significant variables were included in a logistic regression model to further evaluate the independent risk factors for HBEs in shoulder arthroscopic surgery under ISB. Results: The incidence of HBEs was 14.0% (357/2549). Logistic regression analysis revealed that the intraoperative use of hydralazine (odds ratio [OR] 4.2; 95% confidence interval [CI] 2.9–6.3), propofol (OR 2.1; 95% CI 1.3–3.6), and dexmedetomidine (OR 3.9; 95% CI 1.9–7.8) before HBEs were independent risk factors for HBEs in patients who received shoulder arthroscopic surgery under ISB. Conclusions: The intraoperative use of antihypertensives such as hydralazine and sedatives such as propofol or dexmedetomidine leads to increased risk of HBEs during shoulder arthroscopic surgery under ISB in the sitting position.

Download Full-text

A binary logistic regression IN PREDICTING severe influenza in pregnant women

Siberian medical review ◽

10.20333/2500136-2019-4-113-116 ◽

2019 ◽

Vol 4 (4) ◽

pp. 113-116

Author(s):

D.A. Tarbaeva ◽

◽

T.E. Belokrinitskaya ◽

D.M. Serkin ◽

◽

...

Keyword(s):

Logistic Regression ◽

Pregnant Women ◽

Binary Logistic Regression ◽

Severe Influenza

Download Full-text

Binary Logistic Regression Analysis of Variables That Influence Poverty in Central Java

Journal of Intelligent Computing & Health Informatics ◽

10.26714/jichi.v1i1.5381 ◽

2020 ◽

Vol 1 (1) ◽

Author(s):

Sendi Nugraha Nurdiansah ◽

Laelatul Khikmah

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Logistic Regression Analysis ◽

Binary Logistic Regression ◽

Equation Model ◽

Binary Logistic Regression Analysis ◽

Poor People ◽

Regional Government ◽

Central Java ◽

The Government

The phenomenon of poverty is a serious problem faced by almost every country in the world. This is because poverty can affect various aspects of people's lives. One of the causes of poverty is due to lack of income and assets to meet basic needs such as food, clothing, housing, health level and acceptable education. In addition, poverty occurs because of the powerlessness of society to get out of the problems it faces. The Central Java regional government incorporated poverty issues into the Regional Medium-Term Development Plan (RPJMD) because Central Java has a high number of poor people. This was done as an effort by the Central Java government to reduce poverty. Therefore, research is needed to find out the variables that most influence poverty in order to assist the government in developing the RPJMD. To find out what factors influence poverty in Central Java with the dichotomous categorical response variable, binary logistic regression analysis was used. The results showed that based on the analysis conducted did not obtain a logistic regression equation model because there were no significant parameters because there were no variables that had a sig value <0.05. Existing variables are Number of Population, Female Head of Household, Number of Children not in School, Number of Disabled Individuals, Number of Chronic Disease Individuals, Unemployment, Non-Electricity Lighting Sources, Unprotected Drinking Water Sources, Kerosene and Wood Cooking Fuels, Location Facilities Defecation (BAB) Not Available, so there are no variables that affect the level of poverty in Central Java Province.

Download Full-text