scholarly journals Antidepressant use and depressive symptomatology among older people from the Australian Longitudinal Study of Ageing

2010 ◽  
Vol 22 (3) ◽  
pp. 437-444 ◽  
Author(s):  
Ying Zhang ◽  
Veronica Chow ◽  
Agnes I. Vitry ◽  
Philip Ryan ◽  
Elizabeth E. Roughead ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Longitudinal Study ◽  
Health Status ◽  
Depressive Symptomatology ◽  
Depression Scale ◽  
Epidemiologic Studies ◽  
Self Report ◽  
Perceived Health Status ◽  
Australian Longitudinal Study ◽  
Antidepressant Use

ABSTRACTBackground:Depression is one of the leading contributors to the burden of non-fatal diseases in Australia. Although there is an overall increasing trend in antidepressant use, the relationship between use of antidepressants and depressive symptomatology is not clear, particularly in the older population.Methods:Data for this study were obtained from the Australian Longitudinal Study of Ageing (ALSA), a cohort of 2087 people aged over 65 years at baseline. Four waves of home interviews were conducted between 1992 and 2004 to collect information on sociodemographic and health status. Depressive symptoms were measured by the Center for Epidemiologic Studies – Depression Scale. Use of antidepressants was based on self-report, with the interviewer able to check packaging details if available. Longitudinal analysis was performed using logistic generalized estimating equations to detect if there was any trend in the use of antidepressants, adjusting for potential confounding factors.Results:The prevalence of depressive symptoms was 15.2% in 1992 and 15.8% in 2004 (p> 0.05). The prevalence of antidepressant users increased from 6.5% to 10.9% (p< 0.01) over this period. Among people with depressive symptoms, less than 20% were taking antidepressants at any wave. Among people without depressive symptoms, the prevalence of antidepressant use was 5.2% in 1992 and 12.0% in 2004 (p< 0.01). Being female (OR = 1.67, 95%CI: 1.25–2.24), having poor self-perceived health status (OR = 1.17, 95%CI: 1.04–1.32), having physical impairment (OR = 1.48, 95%CI: 1.14–1.91) and having depressive symptoms (OR = 1.62, 95%CI: 1.24–2.13) significantly increased the use of antidepressants, while living in community (OR = 0.51, 95%CI: 0.37–0.71) reduced the risk of antidepressant use.Conclusions:Use of antidepressants increased, while depressive symptoms remained stable, in the ALSA over a 12-year period. Use of antidepressants was low for people with depressive symptoms.

scholarly journals Duration of depressive symptoms and mortality risk: The English Longitudinal Study of Ageing (ELSA)

2016 ◽  
Vol 208 (4) ◽  
pp. 337-342 ◽  
Author(s):  
James White ◽  
Paola Zaninotto ◽  
Kate Walters ◽  
Mika Kivimäki ◽  
Panayotes Demakakos ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Longitudinal Study ◽  
Mortality Risk ◽  
Depression Scale ◽  
Epidemiologic Studies ◽  
Symptom Duration ◽  
Functional Impairments ◽  
Hazard Ratios ◽  
And Gender ◽  
English Longitudinal Study

BackgroundThe relationship between the duration of depressive symptoms and mortality remains poorly understood.AimsTo examine whether the duration of depressive symptoms is associated with mortality risk.MethodData (n = 9560) came from the English Longitudinal Study of Ageing (ELSA). We assessed depressive symptom duration as the sum of examinations with an eight-item Center for Epidemiologic Studies Depression Scale score of ⩾3; we ascertained mortality from linking our data to a national register.ResultsRelative to those participants who never reported symptoms, the age- and gender-adjusted hazard ratios for elevated depressive symptoms over 1, 2, 3 and 4 examinations were 1.41 (95% CI 1.15–1.74), 1.80 (95% CI 1.44–2.26), 1.97 (95% CI 1.57–2.47) and 2.48 (95% CI 1.90–3.23), respectively (P for trend <0.001). This graded association can be explained largely by differences in physical activity, cognitive function, functional impairments and physical illness.ConclusionsIn this cohort of older adults, the duration of depressive symptoms was associated with mortality in a dose–response manner.

Extent of depressive symptomatology among patients seeking care in prepaid group practice

1983 ◽  
Vol 13 (1) ◽  
pp. 121-129 ◽  
Author(s):  
Janet R. Hankin ◽  
Ben Z. Locke
Keyword(s):  
Internal Medicine ◽  
Mental Health ◽  
Depressive Symptoms ◽  
Depressive Symptomatology ◽  
Depression Scale ◽  
Epidemiologic Studies ◽  
Adult Patients ◽  
Group Practice ◽  
Health Practitioner ◽  
Health Practitioners

SynopsisA total of 1921 consecutive adult patients seen in the Departments of Internal Medicine and Obstetrics–Gynaecology at a prepaid group practice completed a self-administered depressive symptomatology questionnaire, the Centre for Epidemiologic Studies Depression Scale (CES-D). New health practitioners and physicians, who were not mental health specialists, blindly judged the presence or absence of depressive symptomatology. Twenty-one per cent of the patients suffered from depressive symptoms according to the CES-D, but only 15% of these were judged to be depressed by their physician or new health practitioner. The variables which predict the recognition of depressive symptomatology are discussed.

PREVALENCE AND CORRELATES OF THE PREMENSTRUAL SYNDROME IN ADOLESCENCE

PEDIATRICS ◽  
1994 ◽  
Vol 93 (2) ◽  
pp. 302-302
Author(s):  
Shyamala Nada Raja ◽  
Michael Feehan ◽  
Warren R. Stanton ◽  
Rob McGee
Keyword(s):  
Mental Health ◽  
Longitudinal Study ◽  
Health Status ◽  
Premenstrual Syndrome ◽  
Self Report ◽  
Maternal Influence ◽  
Physical And Mental Health ◽  
Perceived Health Status ◽  
Health And Development ◽  
Old Females

In a longitudinal study of their health and development, 384 15-year-old females reported their experience of symptoms indicative of premenstrual syndrome (PMS). The prevalence of these symptoms is reported and a group of adolescents is identified with the syndrome (14%). PMS was associated with current self-reported anxiety, inattention, and poor health. Preadolescent self-report and maternal ratings of physical and mental health did not significantly predict adolescent PMS. The results suggest that the experience of PMS in adolescence may be mediated by perceived health status; the roles of mental health and maternal influence in the development of adolescent PMS may be minimal.

scholarly journals Onset of depressive symptomatology in a sample of university students

2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Omar Enzo Santangelo ◽  
Sandro Provenzano ◽  
Dario Piazza ◽  
Alberto Firenze
Keyword(s):  
Health Status ◽  
Informed Consent ◽  
Depressive Symptomatology ◽  
Self Report ◽  
High Grade ◽  
Perceived Health Status ◽  
Online Questionnaire ◽  
Independent Variables ◽  
Increased Risk ◽  
The University

The aim of the study was to evaluate depressive symptomatology within the student population of the University of Palermo (Italy). An anonymous online questionnaire was provided to the students of the University of Palermo. The first section investigated demographic and social data, while in the second section the QIDSSR16 (Quick Inventory of Depressive Symptomatology Self-Report) test was administered. 539 students (68.3% female) gave informed consent and completed the questionnaire. Considering as a dependent variable: Depressive symptomatology moderate- severe-very severe, the statistically significant independent variables associated are I don’t live with my family (aOR 1.63, 95% CI 1.01-2.63, P=0.043), I currently smoke (aOR 1.55, 95% CI 1.01-2.39, P=0.048) and Low perceived health status (aOR 4.14, 95% CI 2.73-6.28, P<0.001). Smoking is associated with an increased risk of developing a high-grade depressive symptomatology. Family plays a crucial role in decreasing the risk of moderate, severe or very severe symptoms.

scholarly journals Onset of depressive symptomatology in a sample of university students

2018 ◽  
Vol 10 (1) ◽  
pp. 8-11
Author(s):  
Omar Enzo Santangelo ◽  
Sandro Provenzano ◽  
Dario Piazza ◽  
Alberto Firenze
Keyword(s):  
Health Status ◽  
Informed Consent ◽  
Depressive Symptomatology ◽  
Self Report ◽  
High Grade ◽  
Perceived Health Status ◽  
Online Questionnaire ◽  
Independent Variables ◽  
Increased Risk ◽  
The University

The aim of the study was to evaluate depressive symptomatology within the student population of the University of Palermo (Italy). An anonymous online questionnaire was provided to the students of the University of Palermo. The first section investigated demographic and social data, while in the second section the QIDSSR16 (Quick Inventory of Depressive Symptomatology Self-Report) test was administered. 539 students (68.3% female) gave informed consent and completed the questionnaire. Considering as a dependent variable: Depressive symptomatology moderate-severe-very severe, the statistically significant independent variables associated are I don't live with my family (aOR 1.63, 95% CI 1.01-2.63, P=0.043), I currently smoke (aOR 1.55, 95% CI 1.01-2.39, P=0.048) and Low perceived health status (aOR 4.14, 95% CI 2.73-6.28, P<0.001). Smoking is associated with an increased risk of developing a high-grade depressive symptomatology. Family plays a crucial role in decreasing the risk of moderate, severe or very severe symptoms.

The Chronicity of Depressive Symptoms in Mothers of Children With Asthma

2017 ◽  
Vol 40 (11) ◽  
pp. 1581-1597 ◽  
Author(s):  
Joan Kub ◽  
Melissa H. Bellin ◽  
Arlene Butz ◽  
Mary Elizabeth Bollinger ◽  
Cassia Lewis-Land ◽  
...  
Keyword(s):  
Social Support ◽  
Depressive Symptoms ◽  
Growth Curve ◽  
Low Income ◽  
Depressive Symptomatology ◽  
Depression Scale ◽  
Asthma Severity ◽  
Epidemiologic Studies ◽  
Psychological State ◽  
Growth Curve Analysis

Depression can disproportionately affect low-income women. The purpose of this study was to explore the chronicity of depressive symptoms in a sample of 276 low-income inner-city mothers of children with high-risk asthma. The aims were to identify factors (asthma health status, stress, social support) associated with change in depressive symptomatology over 12 months as well as to ascertain what factors are most consistently associated with depressive symptoms. Using latent growth curve analysis, demographic variables, asthma severity, stress, and social support failed to explain changes in depressive symptomatology. The growth curve models, however, were predictive of Center for Epidemiologic Studies–Depression Scale (CES-D) scores at distinct time points indicating that higher daily stress and lower social support were associated with increased depressive symptoms. Our data highlight the chronic nature of depressive symptoms in low-income mothers of children with poorly controlled asthma. Integrating questions about caregiver psychological state across all clinical encounters with the family may be indicated.

scholarly journals The Impact of Transitions in Caregiving Status on Depressive Symptoms among Older Family Caregivers: Findings from the Korean Longitudinal Study of Aging

2020 ◽  
Vol 18 (1) ◽  
pp. 42
Author(s):  
Kyungduk Hurh ◽  
Hin Moi Youn ◽  
Yoon Sik Park ◽  
Eun-Cheol Park ◽  
Sung-In Jang
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Longitudinal Study ◽  
Family Caregivers ◽  
Depression Scale ◽  
Estimating Equation ◽  
Epidemiologic Studies ◽  
Equation Model ◽  
Significant Difference ◽  
The Impact

This study identifies the effects of transitions in caregiving status on depressive symptoms among middle-aged or older adults who care for family members with limitations in activities of daily living (ADL). Data were collected from the 2006–2018 Korean Longitudinal Study of Aging. A total of 7817 subjects were included. On the basis of their caregiving status transition, participants were categorized into four groups: started caregiving, continued caregiving, stopped caregiving, and noncaregivers. Depressive symptoms were measured using the 10 item Center for Epidemiologic Studies Depression Scale. Analysis using a generalized estimating equation model and subgroup analyses were conducted. Compared to noncaregivers, women who started caregiving showed more depressive symptoms in the following year (β 0.761, p < 0.0001). Regardless of sex, older adults who continued caregiving had more depressive symptoms than noncaregivers did (β 0.616, p < 0.0277 in men, and β 1.091, p < 0.0001 in women). After relinquishing caregiving responsibilities to other caregivers, participants’ depressive symptoms in the following year showed no statistically significant difference from that of noncaregivers. Thus, starting or continuing caregiving was associated with increased depressive symptoms, and those symptoms could be normalized by stopping caregiving. Intervention strategies to reduce family caregivers’ depressive symptoms are needed.

scholarly journals Antidepressants strongly influence the relationship between depression and heart rate variability: findings from The Irish Longitudinal Study on Ageing (TILDA)

2014 ◽  
Vol 45 (3) ◽  
pp. 623-636 ◽  
Author(s):  
C. O'Regan ◽  
R. A. Kenny ◽  
H. Cronin ◽  
C. Finucane ◽  
P. M. Kearney
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Longitudinal Study ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Linear Regression Analysis ◽  
Depression Scale ◽  
Low Frequency ◽  
Antidepressant Medication ◽  
Epidemiologic Studies ◽  
Self Report

BackgroundHeart rate variability (HRV) is known to be reduced in depression; however, is unclear whether this is a consequence of the disorder or due to antidepressant medication.MethodsWe analysed data on 4750 participants from the first wave of The Irish Longitudinal Study on Ageing (TILDA). Time [standard deviation of normal to normal intervals (SDNN ms2)] and frequency domain [low frequency (LF) and high frequency (HF)] measures of HRV were derived from 3-lead surface electrocardiogram records obtained during 10 min of supine rest. Depression was assessed using the Center for Epidemiologic Studies – Depression scale.ResultsParticipants on antidepressants [with (n = 80) or without depression (n = 185)] differed significantly from controls (not depressed and not taking antidepressants n = 4107) on all measures of HRV. Depressed participants not taking antidepressants (n = 317) did not differ from controls on any measures of HRV. In linear regression analysis adjusted for relevant factors all antidepressants were associated with lower measures HRV. Participants on selective serotonin reuptake inhibitors (SSRIs) had higher measures of HRV relative to participants on tricyclic antidepressants or serotonin–norepinephrine reuptake inhibitors respectively.ConclusionsOur results suggest that reductions in HRV observed among depressed older adults are driven by the effects of antidepressant medications. SSRIs have less impact on HRV than other antidepressants but they are still associated with lower measures of HRV. Study limitations include the use of a self-report measure of depression and floor effects of age on HRV could have limited our ability to detect an association between HRV and depression.

scholarly journals Low vitamin B12 but not folate is associated with incident depressive symptoms in community-dwelling older adults: a 4 year longitudinal study

2021 ◽  
pp. 1-22
Author(s):  
Eamon Laird ◽  
Aisling M. O’Halloran ◽  
Anne M Molloy ◽  
Martin Healy ◽  
Belinda Hernandez ◽  
...  
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Longitudinal Study ◽  
Regression Models ◽  
Plasma Concentrations ◽  
Depression Scale ◽  
Community Dwelling ◽  
Vitamin B ◽  
Folate Status ◽  
Antidepressant Use

Abstract The objective was to examine the prospective relationship between folate and vitamin B12 (B12) status and incident depressive symptoms in a representative cohort of community-dwelling older people. This was a longitudinal study utilising the Irish Longitudinal Study on Aging (n =3,849 aged ≥50 years) and investigated the relationship between blood plasma folate and B12 levels at baseline (wave 1) and incident depressive symptoms at 2 and 4 years (waves 2 and 3). Participants with depression at wave 1 were excluded. A score ≥9 on the Center for Epidemiologic Studies Depression Scale-8 at wave 2 or 3 was indicative of incident depressive symptoms. Plasma B12 and folate concentrations were determined by microbiological assay. B12 status profiles (pmol/l) were defined as: <185, deficient-low; 185 - <258, low normal; >258 - 601, normal and >601 high. Folate status profiles (nmol/l) were defined as: ≤10.0, deficient-low; >10 - 23.0, low normal; >23.0 - 45.0, normal; >45.0, high. Logistic regression models reporting odds ratios were used to analyse the longitudinal association of B-vitamin categories with incident depression. Both B12 and folate plasma concentrations were lower in the group with incident depressive symptoms vs. non depressed (folate: 21.4 vs. 25.1 nmol/L; P=0.0003); (B12: 315.7 vs. 335.9 pmol/L; P=0.0148). Regression models demonstrated that participants with deficient-low B12 status at baseline had a significantly higher likelihood of incident depression four years later (odds ratio 1.51, 95% CI 1.01-2.27, P=0.043). This finding remained robust after controlling for relevant covariates including physical activity, chronic disease burden, vitamin D status. cardiovascular disease and antidepressant use. No associations of folate status with incident depression were observed. Older adults with deficient-low B12 status had a 51% increased likelihood of developing depressive symptoms over 4 years. Given the high rates of B12 deficiency, these findings are important and highlight the need to further explore the low cost benefits of optimising vitamin B12 status for depression in older adults.

scholarly journals Impact of measurement frequency on self-reported depressive symptoms: An experimental study in a clinical setting

2020 ◽  
Author(s):  
Nicole Geschwind ◽  
Martijn van Teffelen ◽  
Elin Hammarberg ◽  
Arnoud Arntz ◽  
M.J.H. Huibers ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Symptoms ◽  
Depressive Symptom ◽  
Depressive Disorder ◽  
Depressive Symptomatology ◽  
Depression Scale ◽  
Self Report ◽  
Major Depressive ◽  
Measurement Frequency ◽  
Symptom Scores

Background: Previous research suggests a relationship between measurement frequency of self-reported depressive symptoms and change in depressive symptom scores for the Beck Depression Inventory II (BDI-II). The goal of the current study was to investigate the differential effects of weekly and monthly completion of the BDI-II and Quick Inventory of Depressive Symptomatology self-report (QIDS-SR). Methods: Seventy individuals diagnosed with major depressive disorder (MDD) waiting for treatment were randomly assigned to either completing BDI-II weekly, BDI-II monthly, QIDS-SR weekly, or QIDS-SR monthly for a duration of nine weeks. After nine weeks participants also completed the Zung depression scale once. Mixed multilevel regression modelling and Bayesian Statistical Analysis were used to test the relationship between the measurement frequency and depression scores, and to compare scores of the repeatedly completed instruments with the instrument completed only in week nine.Results: Measurement frequency was not related to BDI-II, QIDS-SR or Zung scores. However, depression scores declined in the weekly and monthly QIDS-SR (but not BDI-II) conditions, while Bayesian analyses indicated moderate support for equal depression scores on the Zung SDS.Limitations: Lack of a clinician-rated depression scale at week nine in addition to the self-report measure. Conclusion: In contrast to previous studies in non-clinical samples, our findings suggest that measurement frequency does not have an impact on scores of the BDI-II. Implications for clinical studies monitoring depressive symptom scores with self-report scales are discussed. Keywords: major depressive disorder; retest effects; measurement error; measurement frequency; Beck Depression Inventory; Quick Inventory of Depressive Symptomatology

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