Chronogenetics. Its Foundations, Scope, and Impact

1974 ◽  
Vol 23 (S1) ◽  
pp. 131-143
Author(s):  
L. Gedda ◽  
G. Brenci
Keyword(s):  
Preventive Medicine ◽  
Animal Species ◽  
Higher Plants ◽  
Cosmic Time ◽  
Future Perspective ◽  
Fourth Dimension ◽  
Biological Time ◽  
Normal Human ◽  
Object Of Study ◽  
The Relationship

Many chronological correlations in different plant and animal species, in populations, in human families, and between cotwins, prove the existence of characteristic biological times. Some such times also tend to be related to cosmic time, in which they develop and from which they are induced, resulting in peculiar composite times, such as the daily, monthly, or annual rhythms, that are the object of study of chronobiology.Beyond these examples of exogenous chronological induction, the existence of a hereditary biological time is postulated, as the basic phenomenon in the relationship between time and life. The newborn scientific branch of “chronogenetics” is devoted to the study of the fundamental, endogenous genetic time, with its theoretical and practical, normal and pathologic implications. To explain and interpret the mechanisms of the hereditary biological time, the authors have developed a model based on the concepts of “ergon” (i.e., stability of the gene) and “chronon” (i.e., lifespan of the information). This Ergon/Chronon System is related to the gene, bringing into focus the fourth dimension and the dynamic aspects of unit of inheritance.The applications of chronogenetics extend to every expression of life, from the most primitive unicellular to the higher plants and animals. In the area of normal human traits, the study of the hereditary biological time contributes significantly to the interpretation of such phenomena as development, reproduction, homeostasis, and senescence. In the area of medicine, chronogenetics interpretes, unifies, and develops the temporal phenomena of inheritance. In a future perspective, chronogenetics appears to be fundamental for eugenics, preventive medicine, and prognosis.

Chronogenetics. Its Foundations, Scope, and Impact

1973 ◽  
Vol 22 (1) ◽  
pp. 3-17 ◽  
Author(s):  
L. Gedda ◽  
G. Brenci
Keyword(s):  
Preventive Medicine ◽  
Animal Species ◽  
Higher Plants ◽  
Cosmic Time ◽  
Future Perspective ◽  
Fourth Dimension ◽  
Biological Time ◽  
Normal Human ◽  
Object Of Study ◽  
The Relationship

SummaryMany chronological correlations in different plant and animal species, in populations, in human families, and between cotwins, prove the existence of characteristic biological times. Some such times also tend to be related to cosmic time, in which they develop and from which they are induced, resulting in peculiar composite times, such as the daily, monthly, or annual rhythms, that are the object of study of chronobiology.Beyond these examples of exogenous chronological induction, the existence of a hereditary biological time is postulated, as the basic phenomenon in the relationship between time and life. The newborn scientific branch of chronogenetics is devoted to the study of the fundamental, endogenous genetic time, with its theoretical and practical, normal and pathologic implications. To explain and interpret the mechanisms of the hereditary biological time, the authors have developed a model based on the concepts of ergon (i.e., stability of the gene) and chronon (i.e., lifespan of the information). This Ergon/Chronon System is related to the gene, bringing into focus the fourth dimension and the dynamic aspects of the unit of inheritance.The applications of chronogenetics extend to every expression of life, from the most primitive unicellular to the higher plants and animals. In the area of normal human traits, the study of the hereditary biological time contributes significantly to the interpretation of such phenomena as development, reproduction, homeostasis, and senescence. In the area of medicine, chronogenetics interpretes, unifies, and develops the temporal phenomena of inheritance. In a future perspective, chronogenetics appears to be fundamental for eugenics, preventive medicine, and prognosis.

Chronogenetics: A Meeting Point for Medicine and Twin Research

1984 ◽  
Vol 33 (3) ◽  
pp. 343-347
Author(s):  
Luigi Gedda
Keyword(s):  
Preventive Medicine ◽  
Genetic Information ◽  
Time Schedule ◽  
Twin Research ◽  
Meeting Point ◽  
Biological Time ◽  
Object Of Study ◽  
Natural Test ◽  
Mz Twins ◽  
Modern Perspective

AbstractThe program of any individual's vital cycle encoded in the genetic information is executed according to a time schedule that is the object of study of Chronogenetics. MZ twins provide the best evidence of the existence of this hereditary biological time and they represent, therefore, the natural test of Chronogenetics. Twin research can thus serve medicine in developing its most modern perspective, individual preventive medicine. Moreover, through approaches such as the Twins-Living-Apart Test, twin research can help to identify the influences of the environment on the health of man.

Actor Relations in Interregional Cooperation Policy Dynamics Case Study: The Banjar Bakula Metropolitan Area Development Program in South Kalimantan Province

2018 ◽  
Vol 2 (2) ◽  
pp. 115
Author(s):  
Taufik Abrain
Keyword(s):  
Regional Cooperation ◽  
Development Program ◽  
Policy Dynamics ◽  
Interregional Cooperation ◽  
Object Of Study ◽  
Relationship Of ◽  
The Relationship ◽  
Area Development ◽  
Cooperation Policy

Several studies have shown that the success of interregional cooperation may be influenced by coordination, commitment, participation, variance of cooperation, structure, format of cooperation, and political will. Nevertheless, these factors do not stand alone since actor relations as a determining aspect is capable of driving those factors effectively. This article aims to examine the aspect of actor relations as a contributing factor that determines successful cooperation among regions. This is a qualitative research with the policy of inter-regional cooperation of the Banjarbakula Program, South Kalimantan Province from February 2017 to February 2018, set as its object of study. The result of this study states that the success of inter-regional cooperation is influenced by the relationship of actors in development factors as suggested by previous experts. The actors involved in the inter-regional cooperation examined in this case had become triggers of coordination, commitment, and participation toward success and failure, as well as the effectiveness of regional cooperation policy. Structural obstacles, ego-centric character, minimum budget availability, and non-visionary planning could be overcome as long as actor relations were properly managed.

Cell loss from human, canine and guinea-pig gastric mucosa measured by DNA radioimmunoassay

1984 ◽  
Vol 66 (6) ◽  
pp. 701-708 ◽  
Author(s):  
B. C. Hurst ◽  
W. D. W. Rees ◽  
A. Garner
Keyword(s):  
Guinea Pig ◽  
Animal Species ◽  
Colorimetric Assay ◽  
Cell Loss ◽  
Mucosal Cell ◽  
Normal Human ◽  
Dna Loss ◽  
Guinea Pig Stomach ◽  
Pavlov Pouch ◽  
Stimulation Of

1. A DNA radioimmunoassay, sensitive in the range 25–1000 ng, has been developed to measure gastric mucosal cell loss. Validity of the assay was based on antibody specificity, absence of interference from gastric contents, parallel tracer displacement by dilutions of gastric and standard DNA, and crossover with colorimetric assay. 2. With this assay, gastric DNA shedding was examined in two animal species and man. In the guinea-pig stomach, DNA loss was 20–100 pg/h and in the canine Pavlov pouch, 260–580pg/h. In the canine Pavlov pouch stimulation of acid secretion by histamine and exposure to exogenous acid increased DNA output. In the normal human stomach DNA loss was 544 k 175 pg/h and in duodenal ulcer patients, 649 k 225 pg/li. 3. DNA radioimmunoassay provides a sensitive and reproducible measure of cell exfoliation from the stomach and may be a useful tool for studying aspects of gastric mucosal defence.

Antenatal corticosteroid therapy and blood pressure at 14 years of age in preterm children

2000 ◽  
Vol 98 (2) ◽  
pp. 137-142 ◽  
Author(s):  
L. W. DOYLE ◽  
G. W. FORD ◽  
N. M. DAVIS ◽  
C. CALLANAN
Keyword(s):  
Blood Pressure ◽  
Corticosteroid Therapy ◽  
Animal Species ◽  
Antenatal Corticosteroid ◽  
Antenatal Corticosteroids ◽  
Preterm Children ◽  
Clinical Hypertension ◽  
Blood Pressures ◽  
The Relationship ◽  
Mercury Sphygmomanometer

Antenatal corticosteroid therapy substantially improves the survival rate of preterm infants, with few side effects. Higher blood pressure in adulthood has been described in several animal species after exposure to antenatal corticosteroids, but there are no similar reports in humans. The objective of the present study was to determine the relationship between exposure to antenatal corticosteroid therapy and blood pressure at 14 years of age. This was a cohort study of 210 preterm survivors with birthweights of < 1501 g born in the Royal Women's Hospital, Melbourne, between 1 January 1977 and 31 March 1982. Blood pressure was measured in 177 subjects (84.3%) at 14 years of age with a standard mercury sphygmomanometer. Children exposed to antenatal corticosteroids (n = 89) had higher systolic and diastolic blood pressures than those not exposed to corticosteroids (n = 88) [mean difference (95% confidence interval) (mmHg): systolic, 4.1 (0.1–8.0); diastolic, 2.8 (0.05–5.6)]. However, few had blood pressure in the hypertensive range. It is concluded that antenatal corticosteroid therapy is associated with higher systolic and diastolic blood pressures in adolescence, and might lead to clinical hypertension in survivors well beyond birth.

Size Effect on Mechanical Properties of LVL

2014 ◽  
Vol 887-888 ◽  
pp. 824-829
Author(s):  
Qing Fang Lv ◽  
Ji Hong Qin ◽  
Ran Zhu
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Compressive Strength ◽  
Size Effect ◽  
Tensile Test ◽  
Compression Test ◽  
Test Results ◽  
Laminated Veneer Lumber ◽  
Object Of Study ◽  
The Relationship

Laminated veneer lumber is taken as an object of study, and use LVL specimens of different sizes for compression test and tensile test. The goal of the experiment is to investigate the size effect on compressive strength and tensile strength as well as the influence of the secondary glued laminated face, which appears in the secondary molding processes. The results show that both compressive strength and tensile strength have the size effect apparently and the existence of the secondary glued laminated face lower the compressive strength of LVL specimens. Afterwards, the relationship between compressive strength and volume along with tensile strength and area are obtained by the test results.

Regression Analysis on Influences of Hem Parameters on Flare Sagging of Semi-Circular Skirt

2011 ◽  
Vol 331 ◽  
pp. 594-598
Author(s):  
Hong Ni
Keyword(s):  
Regression Analysis ◽  
Statistical Analysis ◽  
Measured Data ◽  
Silk Fabric ◽  
Linear Regression Equation ◽  
Analysis Software ◽  
Wool Fabrics ◽  
Object Of Study ◽  
The Relationship ◽  
Statistical Analysis Software

Select 45 pieces of silk, cotton and wool fabrics in total, with semi-circular skirt modeling as object of study, investigate the relationship between flare sagging in straight & inclined grains of skirt pieces and fabric types, analyze the influence of hem parameters on flare sagging of semi-circular skirt and obtain multiple linear regression equation by disposing the measured data with SPSS statistical analysis software. The study result shows that the skirt hem of silk fabric is sagging more significantly than that of cotton and wool fabrics and there is a multi-linear relationship between semi-circular flare sagging and parameters.The research of this subject has both theoretical value and practical value.

scholarly journals Behavioral Disturbances in Dementia and Beyond: Time for a New Conceptual Frame?

2019 ◽  
Vol 20 (15) ◽  
pp. 3647 ◽  
Author(s):  
Ambrogio ◽  
Martella ◽  
Odetti ◽  
Monacelli
Keyword(s):  
Common Ground ◽  
Psychological Symptoms ◽  
Future Perspective ◽  
Mixed Dementia ◽  
Behavioral Disturbances ◽  
Clinical Issue ◽  
Common Causes ◽  
History Of ◽  
The Relationship ◽  
Prevalent Form

Alzheimer’s disease and vascular dementia are estimated to be the most common causes of dementia, although mixed dementia could represent the most prevalent form of dementia in older adults aged more than 80 years. Behavioral disturbances are common in the natural history of dementia. However, so far, there is a paucity of studies that investigated the causal association between behavioral psychological symptoms of dementia and dementia sub-types, due to the high heterogeneity of methodology, study design and type of clinical assessment. To understand the scant evidence on such a relevant clinical issue, it could be hypothesized that a new shifting paradigm could result in a better identification of the relationship between behavioral disturbances and dementia. This narrative review provides an update of evidence on the behavioral patterns associated with different dementia sub-types and offers a potential future perspective as common ground for the development of new translational studies in the field of behavioral disturbances in dementia and the appropriateness of psychoactive treatments.

scholarly journals Corrupção e violência no sistema penitenciário de São Paulo / Corruption and Violence at São Paulo's Penitenciary Prison

2016 ◽  
Vol 5 (1) ◽  
pp. 207-220
Author(s):  
Marisol de Paula Reis
Keyword(s):  
Social Representations ◽  
Pierre Bourdieu ◽  
Sao Paulo ◽  
São Paulo ◽  
Illegal Activity ◽  
Professional Category ◽  
The Social ◽  
Object Of Study ◽  
Relationship Of ◽  
The Relationship

ABSTRACTThe present work has as object of study the Penitentiary Security ex-Agent (ex-ASP) who is in prison regime by the crime of passive corruption (Article 317 - Brazilian Penal Code). The study answered the following questions: 1) What do staffs and ex-staffs think on the practice of corruption exercised between institutional staffs and some prisoners inside the Sao Paulo's Prisons? 2) What are the representations for the conduct of the ASP's? 3) How do these representations explain the inclusion of some staffs in illegal activity by way of corruption? What is the relationship between corruption and violence? This is a qualitative research with questionnaires and interviews script sticking to the viewpoint of those involved in acts of corruption (the ex-ASP's) and the speeches of the staffs in the exercises of function. The social representations was used as theoretical and methodological axes to present the explanatory elements (material and symbolic) that guide the conduct of this professional category about the corruption and the relationship of this practice with the intramural violence. Authors such as Pierre Bourdieu, Michel Wieviorka, Alves-Mazzoti, Denise Jodelet and Campos Coelho contributed to the discussion proposed.RESUMOO presente trabalho tem como objeto de estudo o ex-Agente de Segurança Penitenciária (ex-ASP) que se encontra em regime de prisão pela prática do crime de corrupção passiva (artigo 317 - Código Penal Brasileiro). O estudo respondeu às seguintes preocupações: 1) O que pensam Agentes Penitenciários e ex-ASP´s sobre a prática da corrupção exercida entre agentes institucionais e alguns presos no interior das prisões de São Paulo? 2) Quais são as representações para tal conduta dos ASP’s? 3) Como essas representações explicam a inserção de alguns agentes penitenciários na atividade ilegal pela via da corrupção? Qual a relação entre corrupção e violência? Trata-se de pesquisa qualitativa, com aplicação de questionários e roteiro de entrevistas, atendo-se ao ponto de vista dos sujeitos envolvidos em atos de corrupção (os ex-ASP´s), e às falas dos agentes de segurança penitenciária em exercício da função. Utilizou-se as representações sociais como eixos teórico e metodológico, para apresentar os elementos explicativos (materiais e simbólicos) que orientam a conduta desta categoria profissional sobre a corrupção, e a relação desta prática com a violência intramuros. Autores como Pierre Bourdieu, Michel Wieviorka, Alves-Mazzoti, Denise Jodelet e Campos Coelho contribuíram para a discussão proposta.

scholarly journals CODE SWITCHING USED BY PUBLIC FIGURES IN DEDDY CORBUZIER'S PODCAST: SOCIOLINGUISTICS APPROACH

JURNAL BASIS ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. 31
Author(s):  
Rika Fiorensera ◽  
Nurma Dhona Handayani
Keyword(s):  
Social Media ◽  
Mutual Influence ◽  
Scientific Discipline ◽  
Code Switching ◽  
Multicultural Environment ◽  
Public Figures ◽  
The Social ◽  
Object Of Study ◽  
The Relationship ◽  
And Linguistics

Sociolinguistics is a joint scientific discipline between sociology and linguistics which means the relationship between society and language. In this case, sociolinguistics is the relationship and mutual influence between language behavior and social behavior. A language is an object of study of the social structures in society as means of communication and group identity. The ability of each human being in the language is different. Some people use two languages in their daily life which is called bilingual. most people like to switch languages with their interlocutors as needed. In sociolinguistics, there is code-switching which is related to bilingualism. Code-switching refers to a kind of code to switch between two languages of the same language at the same time. Code-switching here is a necessary ability to build in an ever-evolving multicultural environment. From social media, people can learn many languages ​​and explore various languages ​​used by others. Almost everyone uses social media. One famous artist who has a YouTube channel with many subscribers is Deddy Corbuzier. In Deddy Corbuzier's podcast, Deddy Corbuzier tends to switch Indonesian English with the other public figures. Therefore, this research aims to describe the types of code-switching using in Deddy Corbuzier podcast. There are three types such as tag switching, intersentential switching, and intrasentential switching. The data was analyzed by using Stockwell (2002) theory. The researchers used descriptive qualitative research methods to research by using (Sudaryanto, 2015). The results of this research, researchers found 3 data for tag switching, 1 data for intersentential switching, and 5 data for intrasentential switching.

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