FACTORS ASSOCIATED WITH PARTIAL REMISSION IN DEPRESSION

1999 ◽  
Vol 27 (3) ◽  
pp. 215-222 ◽  
Author(s):  
Peter L. Cornwall ◽  
Jan Scott
Keyword(s):  
Partial Remission ◽  
Self Esteem ◽  
Significant Loss ◽  
Clinical Implications ◽  
Major Depressive ◽  
Factors Associated ◽  
Full Remission ◽  
Loss Of Self ◽  
Observer Ratings

We report a subgroup analysis of 24 out of 42 subjects who were hospitalized for non-psychotic major depressive disorder and who agreed to participate in interviews at admission and 2 years afterwards (as reported previously by Domken, Scott, & Kelly, 1994; Bothwell & Scott, 1997). At 2 year follow-up, these 24 subjects were categorized according to established criteria into clients meeting criteria for full remission (FR; n=9) and those meeting criteria for partial remission (PR; n=15). The most striking findings were that, over time, PR subjects showed significant loss of self-esteem and showed greater divergence in self-ratings compared to observer ratings of their depressive symptoms, whilst the same ratings in the FR group changed in the opposite direction. We suggest that the persistence of depression in PR subjects may provide evidence to support Teasdale’s (1988) hypothesis that some individuals “get depressed about being depressed”. The research and clinical implications of the results are noted.

Three- to 5-year prospective follow-up of outcome in major depression

1998 ◽  
Vol 28 (3) ◽  
pp. 731-735 ◽  
Author(s):  
L. VAN LONDEN ◽  
R. P. G. MOLENAAR ◽  
J. G. GOEKOOP ◽  
A. H. ZWINDERMAN ◽  
H. G. M. ROOIJMANS
Keyword(s):  
Major Depression ◽  
Partial Remission ◽  
Psychomotor Retardation ◽  
Major Depressive ◽  
Residual Symptoms ◽  
Full Remission ◽  
Depressive Episodes ◽  
Depressive Patients ◽  
Dutch Cohort

Background. A Dutch cohort of predominantly out-patient DSM-III-R major depressive patients was followed for 3 to 5 years after start of treatment in a psycho-neuro-endocrinological prediction study. The study design permitted description of the course of remissions, relapses and recurrences.Methods. Pharmacological treatment was standardized, psychotherapy was tailored to the needs of the patient, follow-ups were done monthly until 3 years or more after the initial recruitment.Results. After 9 months 49% of the patients had reached full remission and 45% were in partial remission. During the following 3 to 5 years 82% of the patients had reached a period of full remission. Sixteen per cent of the patients needed 2 years or more before full remission. A relapse or recurrence rate of 41% within 5 years was found. Patients with residual symptoms relapsed particularly in the first 4 months after remission, while patients without residual symptoms recurred mainly after 12 months after remission. Previous depressive episodes and psychoticism predicted relapse. Psychomotor retardation at inception predicted a longer time to partial remission.Conclusion. In most cases, major depression is a seriously impairing episodic disease. This is also true for a sample of predominantly out-patients treated at a university clinic.

The influence of adversity and perceived social support on the outcome of major depressive disorder in subjects with different levels of depressive symptoms

2006 ◽  
Vol 36 (6) ◽  
pp. 779-788 ◽  
Author(s):  
ULLA LESKELÄ ◽  
HEIKKI RYTSÄLÄ ◽  
ERKKI KOMULAINEN ◽  
TARJA MELARTIN ◽  
PETTERI SOKERO ◽  
...  
Keyword(s):  
Social Support ◽  
Major Depressive Disorder ◽  
Depressive Symptoms ◽  
Depressive Disorder ◽  
Life Events ◽  
Partial Remission ◽  
Perceived Social Support ◽  
Adverse Life Events ◽  
Major Depressive ◽  
Full Remission

Background. Adverse life events and social support may influence the outcome of major depressive disorder (MDD). We hypothesized that outcome would depend on the level of depressive symptoms present at the outset, with those in partial remission being particularly vulnerable.Method. In the Vantaa Depression Study (VDS), patients with DSM-IV MDD were interviewed at baseline, and at 6 and 18 months. Life events were investigated with the Interview for Recent Life Events (IRLE) and social support with the Interview Measure of Social Relationships (IMSR) and the Perceived Social Support Scale – Revised (PSSS-R). The patients were divided into three subgroups at 6 months, those in full remission (n=68), partial remission (n=75) or major depressive episode (MDE) (n=50). The influence of social support and negative life events during the next 12 months on the level of depressive symptoms, measured by the Hamilton Rating Scale for Depression (HAMD), was investigated at endpoint.Results. The severity of life events and perceived social support influenced the outcome of depression overall, even after adjusting for baseline level of depression and neuroticism. In the full remission subgroup, both severity of life events and subjective social support significantly predicted outcome. However, in the partial remission group, only the severity of events, and in the MDE group, the level of social support were significant predictors.Conclusions. Adverse life events and/or poor perceived social support influence the medium-term outcome of all psychiatric patients with MDD. These factors appear to have the strongest predictive value in the subgroup of patients currently in full remission.

Do Psychosocial Factors Influence Outcome in Severely Depressed Female Psychiatric In-patients?

1993 ◽  
Vol 163 (6) ◽  
pp. 747-754 ◽  
Author(s):  
Bernice Andrew ◽  
Keith Hawton ◽  
Joan Fagg ◽  
David Westbrook
Keyword(s):  
Hospital Admission ◽  
Hospital Discharge ◽  
Psychosocial Factors ◽  
Severe Depression ◽  
Self Esteem ◽  
Short Term ◽  
Factors Associated ◽  
Community Or ◽  
Suicidal Ideas

Fifty-nine women admitted to hospital because of severe depression were studied prospectively during hospital admission and nine months following hospital discharge in order to identify psychosocial and illness factors associated with prognosis. Outcome was measured in terms of both depression scores and recovery at the time of follow-up. In keeping with the findings of other studies, the outcome was often poor, with only 54% having recovered nine months after discharge, poorer outcome being associated with more negative self-esteem measured when the women were depressed and with suicidal ideas. The findings indicate that in severely depressed women likely to be admitted to hospital, psychosocial factors may have less relevance to outcome, at least in the short term, than in less severely depressed patients studied in community or out-patient samples.

scholarly journals Full remission and relapse of obsessive-compulsive symptoms after cognitive-behavioral group therapy: a two-year follow-up

2010 ◽  
Vol 32 (2) ◽  
pp. 164-168 ◽  
Author(s):  
Daniela Tusi Braga ◽  
Gisele Gus Manfro ◽  
Kátia Niederauer ◽  
Aristides Volpato Cordioli
Keyword(s):  
Group Therapy ◽  
Partial Remission ◽  
Protective Factor ◽  
Cognitive Behavioral ◽  
Obsessive Compulsive ◽  
Obsessive Compulsive Symptoms ◽  
Cognitive Behavioral Group Therapy ◽  
Full Remission ◽  
Behavioral Group

OBJECTIVE: The aim of this study was to assess whether the results obtained with 12 sessions of cognitive-behavioral group therapy with obsessive-compulsive patients were maintained after two years, and whether the degree of symptom remission was associated with relapse. METHOD: Forty-two patients were followed. The severity of symptoms was measured at the end of cognitive-behavioral group therapy and at 18 and 24 months of follow-up. The assessment scales used were the Yale-Brown Obsessive-Compulsive Scale, Clinical Global Impression, Beck Depression Inventory, and Beck Anxiety Inventory. RESULTS: The reduction in symptom severity observed at the end of treatment was maintained during the two-year follow-up period (F = 57.881; p < 0.001). At the end of the treatment, 9 (21.4%) patients presented full remission, 22 (52.4%) presented partial remission, and 11 (26.2%) had unchanged scores in the Yale-Brown Obsessive-Compulsive Scale. After two years, 13 patients (31.0%) presented full remission, 20 (47.6%) had partial remission, and 9 (21.4%) had unchanged Yale-Brown Obsessive-Compulsive Scalescores. The full remission of symptoms at the end of the treatment was a protective factor against relapse (χ2 = 4,962; df = 1; p = 0.026). CONCLUSION: Our findings underscore the importance of attaining full remission of obsessive-compulsive symptoms during treatment and the need for new therapeutic strategies to achieve this.

Efficacy of Cognitive Behavioral Therapy With and Without Medication for Adults With ADHD: A Randomized Clinical Trial

2016 ◽  
Vol 24 (6) ◽  
pp. 889-903 ◽  
Author(s):  
Mariya V. Cherkasova ◽  
Lisa R. French ◽  
Cassidy A. Syer ◽  
Lorne Cousins ◽  
Harry Galina ◽  
...  
Keyword(s):  
Cognitive Behavioral Therapy ◽  
Behavioral Therapy ◽  
Self Esteem ◽  
Self Report ◽  
Cognitive Behavioral ◽  
Adhd Symptoms ◽  
Organizational Skills ◽  
Observer Ratings ◽  
Group Cbt

Objective: Recent trials have demonstrated efficacy of cognitive behavioral therapy (CBT) in medicated adults with ADHD. Efficacy of CBT in unmedicated versus medicated adults remains mostly unknown. We evaluated the effects of group CBT alone versus combined with medication on ADHD symptoms and functional outcomes in adult patients. Method: Eighty-eight adults with ADHD received 12 manualized group CBT sessions, accompanied by individual coaching, either without ( n = 46) or with ( n = 42) medication. Treatment effects were evaluated following treatment and 3-month and 6-month follow-up using un-blinded self-report and observer ratings. Results: CBT + medication resulted in greater improvements than CBT alone in ADHD symptoms, organizational skills, and self-esteem. Group differences diminished over follow-up, as the CBT alone group continued improving, while the combined group maintained the gains. Conclusion: CBT + medication outperformed CBT alone for ADHD symptoms, organizational skills, and self-esteem, although its superiority tended to decrease over follow-up.

A 4-year prospective observational follow-up study of course and predictors of course in body dysmorphic disorder

2012 ◽  
Vol 43 (5) ◽  
pp. 1109-1117 ◽  
Author(s):  
K. A. Phillips ◽  
W. Menard ◽  
E. Quinn ◽  
E. R. Didie ◽  
R. L. Stout
Keyword(s):  
Mental Health Treatment ◽  
Partial Remission ◽  
Body Dysmorphic Disorder ◽  
Proportional Hazards ◽  
Cox Proportional Hazards ◽  
Cumulative Probability ◽  
Full Remission ◽  
Kaplan Meier ◽  
Dsm Iv

BackgroundThis report prospectively examines the 4-year course, and predictors of course, of body dysmorphic disorder (BDD), a common and often severe disorder. No prior studies have prospectively examined the course of BDD in individuals ascertained for BDD.MethodThe Longitudinal Interval Follow-Up Evaluation (LIFE) assessed weekly BDD symptoms and treatment received over 4 years for 166 broadly ascertained adults and adolescents with current BDD at intake. Kaplan–Meier life tables were constructed for time to remission and relapse. Full remission was defined as minimal or no BDD symptoms, and partial remission as less than full DSM-IV criteria, for at least 8 consecutive weeks. Full relapse and partial relapse were defined as meeting full BDD criteria for at least 2 consecutive weeks after attaining full or partial remission respectively. Cox proportional hazards regression examined predictors of remission and relapse.ResultsOver 4 years, the cumulative probability was 0.20 for full remission and 0.55 for full or partial remission from BDD. A lower likelihood of full or partial remission was predicted by more severe BDD symptoms at intake, longer lifetime duration of BDD, and being an adult. Among partially or fully remitted subjects, the cumulative probability was 0.42 for subsequent full relapse and 0.63 for subsequent full or partial relapse. More severe BDD at intake and earlier age at BDD onset predicted full or partial relapse. Eighty-eight percent of subjects received mental health treatment during the follow-up period.ConclusionsIn this observational study, BDD tended to be chronic. Several intake variables predicted greater chronicity of BDD.

scholarly journals Prevalence of Orthorexia Nervosa in a Sample of Patients Attending Sligo/Leitrim Mental Health Services with a Diagnosis of Eating Disorder

2020 ◽  
Author(s):  
Ignazio Graffeo ◽  
Mary Harron ◽  
Edmond O'Mahony
Keyword(s):  
Eating Disorder ◽  
Eating Habits ◽  
Self Esteem ◽  
Poor Quality ◽  
Orthorexia Nervosa ◽  
Irish Society ◽  
Loss Of Self ◽  
Clinical Disorders

Abstract Background: The term Orthorexia derives from the Greek “ortho – correct” and “orexis – appetite”; Orthorexia Nervosa is a pathological fixation with healthy eating that, starting with the idea to obtain a maximum health with a proper diet, leads to malnourishment and other medical sequelae, loss of relationships, loss of self-esteem, poor quality of life in general. Orthorexia, despite receiving broad empirical evidence, is not currently included in any psychiatric diagnostic manual. The main aim of this study is to investigate its presence in a sample of patients already diagnosed with a canonical eating disorder and also to understand eventual overlaps with other clinical disorders in order to optimize treatment and follow up. The ORTO-15 questionnaire, developed by an Italian team of researchers in 2005, was used to achieve the above aims: it is a tool comprehensive of 15 questions that assesses eating habits perceived as healthy. Really interesting and fascinating is to comprehend if people with a diagnosis of eating disorder present orthorectic behaviour and how this emerging reality fits in the Irish society with its peculiarities and uniqueness. Results: The Point Prevalence obtained is 17.9%. The expected rates of Orthorexia Nervosa in the general population are between 6.9% and 57.6%, with a peak of 81.8% in specific populations, fact that places our examined sample in the lower side of the prevalence previously considered in other studies.Conclusions: It is very difficult to comprehend and explain the reasons behind this fact and probably this is due to an overshadowing of symptoms with the major eating disorders. It is also significant the absence of correlation found between OCD and ON and also the fact that ON is more linked to Bulimia Nervosa in our sample rather than Anorexia Nervosa. The results obtained from this study give also a clear indication of the profile of the orthorexic patient, considered that the sample was obtained from a population of people with a diagnosis of Eating Disorder:

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