scholarly journals The Early Motor Repertoire in Preterm Infancy and Cognition in Young Adulthood: Preliminary Findings

2022 ◽  
pp. 1-12
Author(s):  
Sahar Salavati ◽  
Anne E. den Heijer ◽  
Maraike A. Coenen ◽  
Janneke L.M. Bruggink ◽  
Christa Einspieler ◽  
...  
Keyword(s):  
Information Processing ◽  
Executive Function ◽  
Young Adulthood ◽  
Information Processing Speed ◽  
Cognitive Domains ◽  
Speed Of Information Processing ◽  
Preterm Born ◽  
Cognitive Problems

Abstract Objective: Preterm birth poses a risk to cognition during childhood. The resulting cognitive problems may persist into young adulthood. The early motor repertoire in infancy is predictive of neurocognitive development in childhood. Our present aim was to investigate whether it also predicts neurocognitive status in young adulthood. Method: We conducted an explorative observational follow-up study in 37 young adults born at a gestational age of less than 35 weeks and/or with a birth weight below 1200 g. Between 1992 and 1997, these individuals were videotaped up until 3 months’ corrected age to assess the quality of their early motor repertoire according to Prechtl. The assessment includes general movements, fidgety movements (FMs), and a motor optimality score (MOS). In young adulthood, the following cognitive domains were assessed: memory, speed of information processing, language, attention, and executive function. Results: Participants in whom FMs were absent in infancy obtained lower scores on memory, speed of information processing, and attention than those with normal FMs. Participants with aberrant FMs, that is, absent or abnormal, obtained poorer scores on memory, speed of information processing speed, attention, and executive function compared to peers who had normal FMs. A higher MOS was associated with better executive function. Conclusions: The quality of the early motor repertoire is associated with performance in various cognitive domains in young adulthood. This knowledge may be applied to enable the timely recognition of preterm-born individuals at risk of cognitive dysfunctions.

Abstract 248: Baseline Cognitive Impairment a Predictor of Mortality in Cardiovascular Disease

2012 ◽  
Vol 111 (suppl_1) ◽  
Author(s):  
Antonio D Lassaletta ◽  
Frank W Sellke ◽  
Ronald A Cohen
Keyword(s):  
Cardiovascular Disease ◽  
Executive Function ◽  
Cognitive Function ◽  
Cognitive Dysfunction ◽  
Independent Living ◽  
Cognitive Domains ◽  
The Relationship

Objective: Few longitudinal studies have examined outcomes of patients with cardiovascular disease (CVD) in relation to earlier, baseline cognitive function, or examined the relationship between specific cognitive domains and mortality. This study attempted to clarify the relationship between cognitive function and long-term outcomes, particularly mortality, in patients with cardiovascular disease. Methods: One hundred seventy seven participants between 55 and 85 years of age with an established history CVD were recruited from healthcare institutions. A comprehensive neurophysiological test battery was administered to all patients at baseline assessing 4 cognitive domains: language, visual-spatial, memory, and attention-executive function. Composite scores were calculated by averaging z-scores of all component measures. At 6-year the follow-up, of the 136 patients who were still enrolled, the 116 who were still alive were contacted by phone for assessment of level of independent living, and subjective assessment of cognitive function, and quality of life.Results were corrected for age. Results: At follow-up, participants who were deceased had significantly lower baseline attention-executive function (M=-0.51, SD=0.78 vs. M=0.06, SD=0.54 in survivors, p < 0.01). Poorer memory performance at baseline was associated with a greater degree of cognitive dysfunction at follow-up (p = 0.085). No significant relationships were found between baseline cognitive performance and independent living status or quality of life. Conclusion: Impaired executive function was predictive of poorer outcomes, specifically, 6-year mortality. This finding reinforces the frontal nature of vascular cognitive impairments, especially in regard to the long term sequelae of cognitive dysfunction in patients with CVD. The higher mortality observed in patients with baseline executive domain impairment may be due to behaviors such as impaired self-care, treatment adherence and rehab participation or functional impairments that exacerbate health problems, resulting in death. Patients with cardiovascular disease and executive function impairment should be identified and measures taken to address these potential problems.

scholarly journals Cognitive functioning in patients with classical galactosemia: a systematic review

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Merel E. Hermans ◽  
Mendy M. Welsink-Karssies ◽  
Annet M. Bosch ◽  
Kim J. Oostrom ◽  
Gert J. Geurtsen
Keyword(s):  
Information Processing ◽  
Social Cognition ◽  
Executive Functioning ◽  
Processing Speed ◽  
Cognitive Impairments ◽  
Information Processing Speed ◽  
Classical Galactosemia ◽  
Cognitive Domains ◽  
Attention Memory

Abstract Background Patients with the metabolic disorder classical galactosemia suffer from long-term complications despite a galactose-restricted diet, including a below average intelligence level. The aim of the current review was to investigate the incidence and profile of cognitive impairments in patients with classical galactosemia. Method MEDLINE, EMBASE and PsychINFO were searched up to 23 October 2018 for studies examining information processing speed, attention, memory, language, visuospatial functioning, executive functioning and social cognition in patients with confirmed classical galactosemia utilizing standardized neuropsychological tests. Data synthesis followed a narrative approach, since the planned meta-analysis was not possible due to large variability between the neuropsychological assessments. Results Eleven studies were included, including case-studies. The quality of most studies was moderate to low. As a group, patients with classical galactosemia exhibit below average to low scores on all cognitive domains. A large proportion of the patients perform on an impaired level on attention, memory and vocabulary. Evidence for impairments in information processing speed, language, visuospatial functioning and aspects of executive functioning was limited due to the small number of studies investigating these cognitive functions. Social cognition was not examined at all. Conclusions Given the moderate to low quality of the included studies and the limited evidence in many cognitive domains, the incidence of cognitive impairment in patients with classical galactosemia is not yet clear. Both clinicians and researchers encountering patients with classical galactosemia need to be aware of possible cognitive impairments. Future well-designed studies are needed to determine the cognitive profile of classical galactosemia. This can be the basis for the development of intervention strategies.

scholarly journals Cerebral small-vessel disease and decline in information processing speed, executive function and memory

Brain ◽  
2005 ◽  
Vol 128 (9) ◽  
pp. 2034-2041 ◽  
Author(s):  
Niels D. Prins ◽  
Ewoud J. van Dijk ◽  
Tom den Heijer ◽  
Sarah E. Vermeer ◽  
Jellemer Jolles ◽  
...  
Keyword(s):  
Information Processing ◽  
Executive Function ◽  
Processing Speed ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Information Processing Speed ◽  
Vessel Disease

Difficulties in Planning Among Patients with Multiple Sclerosis: A Relative Consequence of Deficits in Information Processing Speed

2013 ◽  
Vol 19 (5) ◽  
pp. 613-620 ◽  
Author(s):  
Emily M. Owens ◽  
Douglas R. Denney ◽  
Sharon G. Lynch
Keyword(s):  
Multiple Sclerosis ◽  
Information Processing ◽  
Processing Speed ◽  
Healthy Controls ◽  
Problem Difficulty ◽  
Sufficient Time ◽  
Information Processing Speed ◽  
Tower Of London ◽  
Planning Ability

AbstractPrevious studies show that MS patients take longer than healthy controls to plan their solutions to Tower of London (TOL) problems but yield conflicting results regarding the quality of their solutions. The present study evaluated performance under untimed or timed conditions to assess the possibility that differences in planning ability only occur when restrictions in solution times are imposed. MS patients (n = 39) and healthy controls (n = 43) completed a computerized version of the TOL under one of two conditions. In the untimed condition, participants were allowed as much time as needed on each problem. In the timed condition, limits were imposed on solution times and time remaining was displayed with each problem. Patients exhibited longer planning times than controls, and the disparity between groups increased with problem difficulty. Planning performance depended upon condition. In the untimed condition, patients and controls performed equally well. When solution times were restricted, however, patients solved fewer problems than controls. MS patients’ planning ability is intact when permitted sufficient time to formulate the required plan. Deficiencies in planning are only evident when time is restricted, and, therefore, are more accurately considered a relative consequence of disease-related problems in information processing speed. (JINS, 2013, 19, 1–8)

Effect of Mood and Food Cues on Information Processing in Women with Bulimia Nervosa and Controls

1997 ◽  
Vol 14 (2) ◽  
pp. 113-120 ◽  
Author(s):  
Frances A. Carter ◽  
Cynthia M. Bulik ◽  
Rachel H. Lawson ◽  
Patrick F. Sullivan ◽  
Jenny S. Wilson
Keyword(s):  
Information Processing ◽  
Bulimia Nervosa ◽  
Processing Speed ◽  
Cue Reactivity ◽  
Information Processing Speed ◽  
Food Cues ◽  
Speed Of Information Processing ◽  
Food Body ◽  
Body Concerns ◽  
And Control

Information-processing speed and cue reactivity were evaluated in women with bulimia nervosa and controls in response to neutral, mood, and food cues in isolation, and mood and food cues in combination. Significant differences were consistently observed between women with bulimia nervosa and control women on information-processing speed for food/body-related words, but not for words unrelated to food/body concerns. As expected, women with bulimia nervosa demonstrated slower processing of information related to food/body concerns. In addition, the presentation of mood and food cues affected speed of information processing. Especially for women with bulimia nervosa, information processing was slowest when either mood or food cues were presented in isolation. Significant cue reactivity was also observed, again especially for women with bulimia nervosa. In conclusion, both transient and more enduring subject characteristics affected information-processing speed. Moreover, the way transient factors were presented significantly affected speed of information processing. This suggests a more complex relationship between cue presentation and information processing than was anticipated.

Cognitive performance and the course of depressive symptoms over 7 years of follow-up: the SMART-MR study

2014 ◽  
Vol 45 (8) ◽  
pp. 1741-1750 ◽  
Author(s):  
M. Kooistra ◽  
N. P. A. Zuithoff ◽  
A. M. Grool ◽  
M. Zinsmeester ◽  
G. J. Biessels ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Cognitive Performance ◽  
Estimating Equation ◽  
Multiple Time ◽  
Information Processing Speed ◽  
Cognitive Domains ◽  
Interaction Terms ◽  
Multiple Time Points ◽  
Mr Study

BackgroundDepressive symptoms and cognitive impairment often co-occur, but their interactive relationship is complex and the direction of causation is still a topic of research. We examined the influence of cognitive performance on the course of depressive symptoms during 7 years of follow-up in patients with vascular disease.MethodWithin the SMART-MR study, 736 patients (mean age 62 ± 10 years) had neuropsychological assessment on four cognitive domains at baseline [memory (MEM), working memory (WMEM), executive functioning (EXEC), and information processing speed (SPEED)]. Depressive symptoms were assessed with the Patient Health Questionnaire-9 (PHQ-9) at baseline and every 6 months during 7 years of follow-up. Generalized Estimating Equation (GEE) models were used to assess the association between cognitive performance with depressive symptoms at multiple time points during follow-up. Interaction terms between the respective cognitive domains and time was included to examine if the course of depressive symptoms differed according to baseline cognitive performance.ResultsThe GEE analyses showed no significant interactions between the respective cognitive domains and time indicating no different course of depressive symptoms according to baseline cognitive performance. Lower MEM, EXEC or SPEED, but not WMEM performance, was significantly associated with more depressive symptoms during follow-up per z score decrease: MEM [B = 0.70, 95% confidence interval (CI) 0.35–1.05]; EXEC (B = 0.88, 95% CI 0.41–1.36), and SPEED (B = 0.57, 95% CI 0.21–0.92).ConclusionsPoorer cognitive performance on the domains MEM, EXEC and SPEED, but not WMEM, was associated with higher levels of depressive symptoms over 7 years of follow-up, but not with a different course of depressive symptoms over time.

scholarly journals Associations of the Lifestyle for Brain Health Index With Structural Brain Changes and Cognition: Results From the Maastricht Study

Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000012572
Author(s):  
Irene S Heger ◽  
Kay Deckers ◽  
Miranda T Schram ◽  
Coen DA Stehouwer ◽  
Pieter C Dagnelie ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Information Processing ◽  
Executive Function ◽  
White Matter ◽  
Processing Speed ◽  
Grey Matter ◽  
White Matter Hyperintensities ◽  
Information Processing Speed ◽  
Brain Health ◽  
Dementia Risk

Background and Objectives:Observational research has shown that a substantial proportion of all dementia cases worldwide is attributable to modifiable risk factors. Dementia risk scores might be useful to identify high-risk individuals and monitor treatment adherence. The objective of this study was to investigate whether a dementia risk score, the LIfestyle for BRAin health (LIBRA) index, is associated with MRI markers and cognitive functioning/impairment in the general population.Methods:Cross-sectional data was used from the observational population-based cohort of The Maastricht Study.. The weighted compound score of LIBRA (including twelve dementia risk and protective factors, e.g. hypertension, physical inactivity) was calculated, with higher scores indicating higher dementia risk. Standardized volumes of white matter, grey matter, CSF (as proxy for general brain atrophy), white matter hyperintensities, and presence of cerebral small vessel disease were derived from 3T MRI. Cognitive functioning was tested in three domains: memory, information processing speed, and executive function and attention. Values ≤1.5 SD below the average were defined as cognitive impairment. Multiple regression analyses and structural equation modelling were used, adjusted for age, sex, education, intracranial volume and type-2 diabetes.Results:Participants (n=4,164; mean age 59y; 49.7% men) with higher LIBRA scores (mean=1.19, range=-2.7 to +9.2), denoting higher dementia risk, had higher volumes of white matter hyperintensities (β=0.051, p=.002), and lower scores on information processing speed (β=-0.067, p=.001) and executive function and attention (β=-0.065, p=.004). Only in men, associations between LIBRA and volumes of grey matter (β=-0.093, p<.001), CSF (β=0.104, p<.001) and memory (β=-0.054, p=.026) were found. White matter hyperintensities and CSF volume partly mediated the association between LIBRA and cognition.Discussion:Higher health- and lifestyle-based dementia risk is associated with markers of general brain atrophy, cerebrovascular pathology and worse cognition, suggesting that LIBRA meaningfully summarizes individual lifestyle-related brain health. Improving LIBRA factors on an individual level might improve population brain health. Sex differences in lifestyle-related pathology and cognition need to be further explored.Classification of Evidence:This study provides Class II evidence that higher LIBRA scores are significantly associated with lower scores on some cognitive domains and a higher risk of cognitive impairment.

Relationships Between University Students’ Gender and Physical Activity (PA) and Their Exercise Self-Schemas, Processing of PA-Related Information, and PA Decision-Making

2021 ◽  
pp. 003151252110601
Author(s):  
In Kyoung Park ◽  
Youngho Kim
Keyword(s):  
Physical Activity ◽  
Decision Making ◽  
Information Processing ◽  
Reaction Time ◽  
University Students ◽  
Information Processing Speed ◽  
Exercise Interventions ◽  
Speed Of Information Processing ◽  
Future Behavior ◽  
Self Schema

In the current study, we investigated the effects of gender and regular physical activity (PA) on PA decision-making and speed of information processing. We enrolled 110 university students ( Mage = 20.91, SD =2.28 years) in an experiment involving two tasks and a questionnaire. One of the two tasks assessed how much participants agreed with presented PA words and phrases and the other task predicted behavior and responses to future situations. We collected and measured the participants’ choices and the time they took to make them. The questionnaire, the International Physical Activity Questionnaire (IPAQ), consisted of exercise self-schema and PA questions. We conducted a 2 (gender: male or female) ×2 (regular PA or not) multivariate analysis of variance (MANOVA) and found statistically significant differences between variables as a function of participants’ gender (λ = .66, p < .001) and regular PA engagement (λ = .51, p < .001). In a regression analysis, we also found gender differences [males showed relationships between agreement with PA information and information processing speed for decisions on future behavior ( R 2 = .31, F = 12.50); females showed relationships between their exercise self-schema ( R 2 = .26, F = 18.18) and regular PA such that, in the non-regular PA group, exercise self-schema was related to reaction time in making decisions on future behavior ( R 2 = .29, F = 11.23), and in the regular PA group, agreement with PA information was related to reaction time for PA-related words, and agreement with non-PA information ( R 2 = .29, F = 8.91)]. These results highlight the need to consider participant characteristics when designing exercise interventions, and we present supplementary data regarding exercise self-schemas, decision-making, and the speed of processing PA information.

Comparison of Two Reaction-Time Tasks and Their Relation to Intelligence

1987 ◽  
Vol 65 (3) ◽  
pp. 867-870 ◽  
Author(s):  
Mark A. Small ◽  
J. F. Raney ◽  
Terry J. Knapp
Keyword(s):  
College Students ◽  
Information Processing ◽  
Reaction Time ◽  
Processing Speed ◽  
Reaction Time Task ◽  
Information Processing Speed ◽  
Time Task ◽  
Speed Of Information Processing ◽  
Time Parameters

Two reaction time tasks were compared as measures of information-processing speed. A multiple R between the WAIS—R Full, Performance, and Verbal scales and several reaction time parameters was calculated for 28 college students. Results indicate that the reaction-time task used in exploring the relationships between speed of information processing and IQ can be less complex than those used to date.

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