scholarly journals Vitamin D status and its relationship with metabolic syndrome risk factors among adolescent girls in Boukan, Iran

2013 ◽  
Vol 17 (4) ◽  
pp. 803-809 ◽  
Author(s):  
Maryam Rafraf ◽  
Saadat Karimi Hasanabad ◽  
Mohammad Asghari Jafarabadi

AbstractObjectiveTo investigate vitamin D status and its association with components of the metabolic syndrome (MetS) in adolescent girls attending high school in Boukan, Iran during winter 2012.DesignA cross-sectional study.SettingHigh schools of Boukan city, Iran.SubjectsA sample of 216 girls aged 14–17 years was selected by multistage random sampling from four districts of Boukan. Weight, height, waist circumference, blood pressure, daily energy intake, physical activity and serum 25-hydroxyvitamin D (25(OH)D), fasting blood glucose, TAG and HDL-cholesterol levels of all participants were evaluated. Serum 25(OH)D level <20 ng/ml was defined as vitamin D deficiency.ResultsMean serum 25(OH)D was 7·26 (sd 2·81) ng/ml and 96 % of the participants had vitamin D deficiency. According to age-modified definitions of the National Cholesterol Education Program Adult Treatment Panel III, MetS was diagnosed in 10·6 % of the participants. In multivariable regression analysis after adjustment for BMI, energy intake and physical activity level, serum 25(OH)D was inversely associated with fasting blood glucose (β = −0·143, P = 0·04). No significant relationship was found between serum 25(OH)D and other components of MetS.ConclusionsThe high prevalence of vitamin D deficiency warrants national polices and interventions towards improving this major health problem among adolescent girls. Low 25(OH)D level was significantly associated with increased fasting blood glucose. Prospective studies are needed to determine the effects of vitamin D deficiency on the development of MetS and related metabolic diseases in adolescent girls.

2018 ◽  
Vol 72 (3) ◽  
pp. 223-230 ◽  
Author(s):  
Janet M. Chiang ◽  
Frank Z. Stanczyk ◽  
Alka M. Kanaya

Background/Aims: Asian Indians have a high prevalence of vitamin D deficiency and metabolic syndrome. Vitamin D deficiency is associated with an increased risk of cardiovascular disease and diabetes. Methods: We performed a cross-sectional study of 150 Asian Indians (50% male) from the San Francisco Bay Area. We assessed the association between 25-OH vitamin D (25-OHD) levels and vitamin D deficiency with body composition (anthropometric and radiographic measures) and metabolic outcomes. Results: In both men and women, the presence of vitamin D deficiency was associated with higher systolic (p = 0.004) and diastolic (p = 0.01) blood pressure, and fasting glucose (p = 0.01). Only in women, vitamin D deficiency status was associated with higher body mass index (BMI), waist-to-hip ratio, visceral fat area, and hepatic fat content after adjusting for age, income, and physical activity level. In women, 25-OHD was also associated with fasting glucose after adjusting for age, income, and physical activity and further adjusting for BMI and waist circumference (β –2.1, 95% CI –0.86 to –0.01, p = 0.04). This association between vitamin D deficiency and metabolic parameters was not significant in men. Conclusions: A lower level of 25-OHD and vitamin D deficiency were associated with higher levels of metabolic factors among Asian Indians. Our findings suggest that 25-OHD metabolism may differ by the distribution of adipose tissue and involve previously unexplored pathways accounting for the variability in the role of vitamin D in cardiovascular disease.


2021 ◽  
Vol 32 (1) ◽  
pp. 31-38
Author(s):  
Quazi Tarikul Islam ◽  
Md Alimur Reza ◽  
Md Khalilur Rahman ◽  
AFM Nazmul Islam ◽  
Saiyeedur Rahman ◽  
...  

Introduction: Vitamin D deficiency has been linked to a whole spectrum of diseases including osteoporosis, cancer, diabetes, and cardiovascular and immune disorders. Though Bangladesh is low latitude country, vitamin D Deficiency is serious and wide spread problem in Bangladesh. Physicians of Bangladesh are more vulnerable to low vitamin D status due to long indoor work hours and lack of sunlight exposure in both government & private institute. So, the aim of this study to evaluate vitamin D status among the physicians working around the Bangladesh. Methods: This was a cross-sectional, multicenter study where we enrolled 1112 doctors from 9 different areas of Bangladesh from May 2018 to June 2019. A Blood sample was collected from all participants to measure Serum 25(OH)D and various patient data such as age, gender, BMI, physical activity level during leisure time, use of vitamins and medications, sunlight exposure time, tea/coffee drinking, smoking, H/O comorbidities etc. was collected. Results: Of the 1112 doctors assessed in the study,794 (71.4%) was male and 318 (28.6%) was female. Mean age of the participants was 45.5±11.1 Years. Vitamin D deficiency and insufficiency was found in 734 (65.8%) and 105 (9.4%) participants respectively. Mean vitamin D level was 18.9 ng/ml (±8.6 ng/ml). Less than 5% of participants of Rajshahi, Rangpur, Dhaka, Bogura and Sylhet had sufficient vitamin D level. Vitamin D deficiency was significantly associated with age, obesity, sunlight exposure, physical inactivity, hypertension and vitamin D supplementation. Conclusion: Vitamin D deficiency is very common among physicians of all over Bangladesh. The high prevalence of vitamin D deficiency in the present study points towards urgent need of an integrated approach to detect vitamin D deficiency among health care professionals and treat appropriately. Bangladesh J Medicine January 2021; 32(1) : 31-38


2021 ◽  
Author(s):  
Yingyi Luo ◽  
Chunbo Qu ◽  
Rui Zhang ◽  
Jingyi Zhang ◽  
Dan Han ◽  
...  

Abstract Background: Vitamin D deficiency is a major public health problem in China while there are seldom reports about vitamin D nutrition status in Chinese college students. The purpose of this study is to explore the vitamin D status of the college freshmen who came from different provinces of China and to comprehensive analyze the effects of diet, physical activity, and UV protection on serum vitamin D levels. Methods: Totally 1,667 freshmen who came from 26 provinces, autonomous districts or municipalities, were recruited into this study. An online questionnaire was used to collect the information including demographic status, diet habit, physical activity, and UV protection of the participants. Serum 25(OH)D3 concentrations were measured using a liquid chromatograph mass spectrometer. Multivariate linear regression analyses were used to explore the comprehensive influence of diet, physical activity, and UV protection on serum 25(OH)D3 levels. Results: The average age of the subjects was18.55±0.90 years, with 23.0% male and 77.0% female. The mean serum 25(OH)D3 was 18.06±6.34ng/mL and the proportion of vitamin D deficiency and insufficiency was 67.5% and 27.8%, respectively. Multivariate linear regression indicated that milk and yogurt intake≥200mL/d, calcium or vitamin D supplements and average time of outdoor activity ≥60 min/day were positively linked to higher serum vitamin D while sweets intake ≥10g/d and higher UV protection index were negatively influenced serum vitamin D after adjusted for age, gender, students’ original residence, latitudes and longitude. Conclusions: Vitamin D deficiency is an important health problem in Chinese college students. Milk and yogurt intake and outdoor activity should be encouraged while sweets intake should be limited for preventing vitamin D deficiency. Public health policies should consider well-balanced guidelines on UV protection and vitamin D food fortification or supplementation.


2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
M. R. Lopes ◽  
Paula A. B. Ribeiro ◽  
Priscila Ledur ◽  
Gabriela C. Souza ◽  
Nadine Clausell ◽  
...  

Vitamin D deficiency is frequent among patients with heart failure (HF) and diabetes, disorders associated with exercise intolerance and muscle weakness. This study aims to search for associations between vitamin D sufficiency and physical function indexes in patients with HF and diabetes. A cross-sectional study of 146 HF patients, 39.7% with diabetes, at a Brazilian tertiary outpatient clinic was performed. Patients underwent clinical evaluation, 6-minute walk test (6 MWT), handgrip strength, physical activity level (IPAQ), and biochemical evaluations including serum 25-hydroxyvitamin D. Classification was done according to vitamin D status (≥30 ng/dL, sufficient) and presence/absence of diabetes in vitamin sufficient, no diabetes (DS-C,n=25), vitamin sufficient, diabetes (DS-DM,n=18), vitamin deficient, no diabetes (DD-C,n= 63), and vitamin deficient, diabetes (DD-DM,n=40). Patients age was 55.4 ± 8 yrs; 70.5% had vitamin D deficiency. Clinical characteristics were similar among groups. Total time expended in physical activity was similar among groups(P=0.26). DS-C covered higher distances in the 6 MWT (392 ± 60 m)versusDD-DM (309 ± 116 m);P=0.024. Handgrip strength was similar among groups but tended to lower levels in DD-DM(P=0.074)even after being adjusted to physical activity(P=0.069). Vitamin D deficiency can influence physical function in HF diabetic patients.


2019 ◽  
Vol 11 (1) ◽  
pp. 42-7
Author(s):  
Mona Hmoud AlSheikh ◽  
Shayma Ibrahim Almubayadh

BACKGROUND: Vitamin D is an essential nutrient requirement for adults and children for normal metabolism and maintenance of healthy bones. Its deficiency may disrupt homeostasis and contribute to systemic diseases, especially in obese patients. This study aimed to examine the effect of vitamin D on insulin, fasting blood glucose (FBG) and waist-hip ratio (WHR) in young and obese Saudi females with pre-existing hypovitaminosis D.METHODS: The results of this study were based on prospective parallel randomised controlled clinical trial conducted at King Fahd University Hospital in which 30 obese Saudi young females aging 18-23 years with preexisting vitamin D deficiency contributed. Participants were randomly assigned to either vitamin D supplementation group (experimental) or placebo group (control). Subjects of vitamin D group received 50,000 IU/week of cholecalciferol drops and placebo group received 10 mL of normal saline drops for 12 weeks.RESULTS: The results of multivariate repeated measures analysis showed a change in serum 25-Hydroxycholecalciferol levels after vitamin D supplementation (F=296.132, p<0.05). There was also an indication of difference between the vitamin D group and placebo group. The only significant relationship was found between vitamin D and FBG (p<0.05). Supplementation of vitamin D improved FBG but did not contribute to improving insulin level. There was no association between vitamin D supplementation and WHR.CONCLUSION: This study concludes that supplementation of vitamin D improves FBG, but it has no contribution in improving insulin level. No association exists between vitamin D supplementation and WHR. The insignificant correlation of vitamin D intake with WHR and insulin can be attributed to the small sample size, therefore, further research is suggested with large sample size.KEYWORDS: vitamin D, fasting blood glucose, body mass index, waist hip ratio, hypovitaminosis D


2017 ◽  
Vol 6 (4) ◽  
pp. 285
Author(s):  
Nur Rochmah ◽  
Enny Probosari ◽  
Fillah Fithra Dieny

Background : Vitamin D and calcium have metabolic functions in the cells and insufficient intake has been proven to increase the risk factor for many chronic diseases, such as diabetes mellitus. Vitamin D and calcium both contribute in raising insulin secretion by regulating extracelullar calcium concentration and fluxing through cell membranes facilitated by calcium-sensing receptor. This study aimed to determine correlation between vitamin D and calcium intake with blood glucose levels in obese woman aged 45-55 years.Methods : Observational study with cross sectional design. Sixty subjects were selected using consecutive sampling. Food intakes were assessed by Semi Quantitative Food Frequency Questionnaire, fasting blood glucose levels were measured by Glucose Oxidation method, and physical activities were determined by Long International Physical Activity Questionnaire. The data were analyzed using r Pearson and Rank-Spearman test. Results : Mean of fasting blood glucose levels was 90,4±37,22 mg/dL with average vitamin D was 4,1 ±2,23 μg, whereas calcium was 547,7±316,24 mg. All subjects had low vitamin D intake; 88,3% subjects had low calcium intake; 88,3% subjects had normal fasting blood glucose; and 11,7% subjects had hyperglycemia. There was no correlation between vitamin D (p = 0,295) and calcium  (p = 0,295) intake with fasting blood glucose levels. Intake of energy, carbohydrate, fat, protein, fiber  and physical activity also showed no corerelation with fasting blood glucose levels. Conclusion : There was no correlation of vitamin D and calcium intake with fasting blood glucose levels in obese woman aged 45-55 years.


2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Linda Ahenkorah Fondjo ◽  
Samuel Asamoah Sakyi ◽  
William K. B. A. Owiredu ◽  
Edwin Ferguson Laing ◽  
Eddie-Williams Owiredu ◽  
...  

Background. Type 2 Diabetes Mellitus (T2DM) and menopause are associated with vitamin D status. Oestrogen decline during menopausal stages promotes hypovitaminosis D. However, the interplay between vitamin D, menopause, lifestyle, and T2DM cannot be overlooked. This study assessed vitamin D status among pre- and postmenopausal T2DM women and determined its association with glycemic control and influence of lifestyle habits on hypovitaminosis D.Methods. This cross-sectional study was conducted at the Komfo Anokye Teaching Hospital, Kumasi, Ghana. Structured questionnaires were administered to 192 T2DM women; blood samples were collected for estimation of 25(OH) D and insulin using ELISA. Fasting blood glucose (FBG), lipid profile, glycated haemoglobin (HbA1c), and calcium were measured. Statistical analyses were performed using Graphpad Prism 6.Results. The prevalence of vitamin D inadequacy was 92.2%. Hypovitaminosis D was more prevalent among the postmenopausal T2DM women (63.8% versus 58.2%). Hypovitaminosis D significantly associated with insulin [R2=0.01760,p=0.0008], HbA1c [R2=0.3709,p=<0.0001], and FBG [R2=0.3465,p=0.0001] in only the postmenopausal women.Conclusion. Vitamin D deficiency is prevalent in pre- and postmenopausal T2DM but higher among postmenopausal women. Adequate vitamin D levels in both groups were associated with improved glucose control while hypovitaminosis D in the postmenopausal women was related to poorer glucose control. Vitamin D screening should be incorporated into management plan for T2DM to serve as an early tool for prevention of vitamin D deficiency.


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