scholarly journals Vitamin B12serostatus in Colombian children and adult women: results from a nationally representative survey

2014 ◽  
Vol 18 (5) ◽  
pp. 836-843 ◽  
Author(s):  
Oscar F Herrán ◽  
Julia B Ward ◽  
Eduardo Villamor
Keyword(s):  
Pregnant Women ◽  
Household Head ◽  
Serum Vitamin ◽  
Vitamin B ◽  
Adult Women ◽  
Representative Survey ◽  
Cross Sectional ◽  
Multivariable Analyses ◽  
Nationally Representative ◽  
Colombian Women

AbstractObjectiveVitamin B12 deficiency is associated with many adverse health outcomes and is highly prevalent worldwide. The present study assesses the prevalence of vitamin B12 deficiency and marginal deficiency in Colombian children and women and examines the sociodemographic correlates of serum vitamin B12 concentrations in these groups.DesignCross-sectional, nationally representative survey.SettingColombia.SubjectsChildren <18 years old (n 7243), pregnant women (n 1781), and non-pregnant women 18–49 years old (n 499).ResultsThe overall prevalence of vitamin B12 deficiency (serum vitamin B12<148 pmol/l) and marginal deficiency (serum vitamin B12=148–221 pmol/l) was, respectively, 6·6 % (95 % CI 5·2 %, 8·3 %) and 22·5 % (95 % CI 21·1 %, 23·9 %). Pregnant women had the highest prevalence of deficiency (18·9 %; 95 % CI 16·6 %, 21·5 %) compared with non-pregnant adult women (18·5 %; 95 % CI 4·4 %, 53·1 %) and children (2·8 %; 95 % CI 2·3 % %, 3·3 %). In multivariable analyses among children, mean serum vitamin B12 was positively associated with female sex (12 pmol/l higher compared with males; P=0·004), secondary or higher education of the household head (12 pmol/l higher compared with primary or less; P=0·009) and food security (21 pmol/l higher compared with severe food insecurity; P=0·003). In multivariable analyses among pregnant women, mean serum vitamin B12 was positively associated with education of the household head and inversely associated with living in the National territories, Eastern or Pacific regions.ConclusionsThe prevalence of vitamin B12 deficiency and marginal deficiency in Colombian women and children is substantial. The burden falls largely on adult women, those with lowest education and those living in the poorest, most rural regions of the country.

scholarly journals An Increased Adverse Fetal Outcome Has Been Observed among Teen Pregnant Women in Rural Eastern Ethiopia: A Comparative Cross-Sectional Study

2021 ◽  
Vol 8 ◽  
pp. 2333794X2199915
Author(s):  
Haymanot Mezmur ◽  
Nega Assefa ◽  
Tadesse Alemayehu
Keyword(s):  
Pregnant Women ◽  
Fetal Outcome ◽  
Cross Sectional Study ◽  
World Health ◽  
Adult Women ◽  
Sectional Study ◽  
Fetal Outcomes ◽  
Cross Sectional ◽  
Eastern Ethiopia ◽  
Adverse Fetal Outcome

Background: According to the World Health Organization, teenage pregnancies are high-risk due to increased risks of fetal and infant morbidity and mortality. This study compares adverse fetal outcomes between teen and adult pregnant women from rural Eastern Ethiopia. Methods: Institutional-based cross-sectional study was conducted among women visiting maternity units from surrounding rural areas. A total of 481 teenagers (13-19 years old) and 481 adults (20-34 years old) women with a singleton pregnancy were included in the study. Two hospitals and 3 health centers were selected in Eastern Hararghe Zone, Eastern Ethiopia. Comparative analysis was carried out using the log-binomial regression model to identify factors associated with adverse fetal outcomes in both categories. The results are reported in adjusted prevalence ratios with 95% confidence intervals. Results: High proportion of adverse fetal outcome was observed among teenage women than adult (34.9% vs 21%). Statistically significant difference ( P < .05) in the proportion of low birth weight (21.1% vs 9.3%), preterm birth (18.7% vs 10.6%), APGAR score at 5th minute (9.3% vs 4%) were found in teenagers compared to adult women. Antenatal care attendance (APR = 0.44; 95% CI: 0.23, 0.86); eclampsia (APR = 1.96; 95% CI: 1.26, 3.06); pre-eclampsia (APR = 1.73; 95% CI: 1.12, 2.67); and wealth index (rich) (APR = 0.55; 95% CI: 0.32, 0.94) were significantly associated with adverse fetal outcomes among the teenage women. Whereas intimate partner violence (APR = 2.22; 95% CI: 1.26, 3.90); preeclampsia (APR = 3.05; 95% CI: 1.61, 5.69); antepartum hemorrhage (APR = 2.77; 95% CI: 1.73, 4.46); and hyperemesis gravderm (APR = 1.75; 95% CI: 1.09, 2.79) were significantly associated with adverse fatal outcomes among the adult women. Conclusion: teenage pregnancy is associated with a high rate of adverse fetal outcomes. Early identification and treatment of problems during antenatal follow-up should be the mainstay to avert the massive adverse fetal effects.

scholarly journals Total Usual Dietary Intakes of Pregnant Women in the United States, 2001-2014 (FS08-01-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Regan Bailey ◽  
Susan Pac ◽  
Victor Fulgoni ◽  
Kathleen Reidy
Keyword(s):  
At Risk ◽  
Folic Acid ◽  
Pregnant Women ◽  
Critical Dimension ◽  
The United States ◽  
Dietary Intakes ◽  
Dietary Recommendations ◽  
Cross Sectional ◽  
Excessive Consumption ◽  
Nationally Representative

Abstract Objectives Nutrition during pregnancy is a critical dimension not only for women’s heath, but also for the offspring’s lifelong health. Very limited national data exist on the usual dietary intakes of pregnant women. The objective of this study was to estimate total usual nutrient intakes (from foods and dietary supplements) of pregnant women in the U.S. Methods Cross-sectional analysis of a nationally-representative sample of pregnant U.S. women, ages 20-40 years (n = 1,003) from NHANES 2001-2014. Total usual dietary intakes were estimated using the National Cancer Institute (NCI) method to adjust 2, 24-hour dietary recalls for within-person variation. Adherence with the Dietary Reference Intakes were used to assess the proportion at risk of inadequacy by the Estimated Average Requirement (%< EAR), assumed to be adequate by the Adequate Intake (% >AI), and at risk of excess by the Tolerable Upper Intake Level (% >UL). Results About 70% of pregnant women use a dietary supplement. Less than 5% of pregnant women have usual diets that are at risk for inadequate intakes of riboflavin (3%), niacin (1%), vitamin B12 (1%), iron (2%), phosphorus (< 0.5%), and selenium (< 0.5%). More pregnant women have usual intakes < EAR for vitamins A (15%), B6 (11%), folate (16%), C (11%), D (46%), E (43%), and minerals including copper (5%), calcium (13%), magnesium (47%) and zinc (11%). Few pregnant females have usual intakes >AI for potassium (2%) and choline (8%), whereas only 48% have vitamin K intakes >AI. The majority of pregnant women (95%) exceed the UL for sodium, while folic acid (34%), iron (28%), calcium (3%), and zinc (7%) were also of concern for intakes >UL. Conclusions Many U.S. pregnant women ( >10% < EAR or < 10% >AI) do not consume enough of key nutrients during pregnancy specifically vitamins A, C, D, E, K, B6, folate, and choline and minerals including potassium, calcium, magnesium, and zinc, while almost all are at risk of excessive consumption of sodium, and many at risk of excessive consumption of folic acid and iron. Improved dietary guidance to help pregnant women meet and not exceed dietary recommendations is warranted. Funding Sources Nestle Nutrition.

scholarly journals TO STUDY OF ASSOCIATION OF CLINICAL PROFILE WITH SERUM VITAMIN B12 AND FOLATE LEVEL IN CHILDREN WITH INFANTILE TREMOR SYNDROME

2021 ◽  
pp. 118-120
Author(s):  
Dinesh Kumar ◽  
Mahesh Kumar Gupta ◽  
Sunil Gothwal ◽  
Umesh Gurjar ◽  
Kailash Kumar Meena ◽  
...  
Keyword(s):  
Serum Vitamin ◽  
Psychomotor Retardation ◽  
Clinical Profile ◽  
Vitamin B ◽  
Folate Level ◽  
Cross Sectional ◽  
Medical College ◽  
Mother And Child Health ◽  
Mother And Child ◽  
And Child Health

Background-We planned the present study with objective of to find out correlation in vitamin B and folate levels with 12 clinical profile in children with ITS Methods- This Hospital based cross sectional observational study was conducted in, Sir Padampat Mother and Child Health Institute (SPMCHI),SMS Medical College,Jaipur. Results- Vitamin B and folate were reduced in children with generalized tremors, psychomotor retardation, delayed 12 milestones,presence of hepatomegaly and splenomegaly. Conclusion- All children with Infantile Tremor Syndrome should be screened for vitamin B and folate levels,high risk 12 children should be supplemented B and folic acid.

Depression — a common disorder across a broad spectrum of neurological conditions: a cross-sectional nationally representative survey

2015 ◽  
Vol 37 (6) ◽  
pp. 507-512 ◽  
Author(s):  
Andrew G.M. Bulloch ◽  
Kirsten M. Fiest ◽  
Jeanne V.A. Williams ◽  
Dina H. Lavorato ◽  
Sandra A. Berzins ◽  
...  
Keyword(s):  
Broad Spectrum ◽  
Representative Survey ◽  
Cross Sectional ◽  
Common Disorder ◽  
Neurological Conditions ◽  
Nationally Representative

scholarly journals Interpretation of vitamin B-12 and folate concentrations in population-based surveys does not require adjustment for inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project

2020 ◽  
Vol 111 (4) ◽  
pp. 919-926 ◽  
Author(s):  
Melissa F Young ◽  
Junjie Guo ◽  
Anne Williams ◽  
Kyly C Whitfield ◽  
Sabiha Nasrin ◽  
...  
Keyword(s):  
Survey Design ◽  
Serum Vitamin ◽  
Correlation Coefficients ◽  
Population Based ◽  
Reproductive Age ◽  
Serum Folate ◽  
Vitamin B ◽  
Cross Sectional ◽  
Population Prevalence ◽  
Vitamin B 12

ABSTRACT Background Vitamin B-12 and folate deficiencies in women and children have important public health implications. However, the evidence is conflicting and limited on whether the influence of inflammation on biomarker concentrations may be sufficiently and consistently influenced by inflammation to require adjustment for interpreting concentrations or estimating population prevalence of deficiencies. Objective We examined correlations between concentrations of the inflammation biomarkers C-reactive protein (CRP) and α1-acid glycoprotein (AGP) and serum vitamin B-12 and serum and RBC folate among nonpregnant women of reproductive age (WRA; 15–49 yr) and preschool children (PSC; 6–59 mo). Methods We analyzed cross-sectional data from 16 nationally representative nutrition surveys conducted in WRA (n = 32,588) and PSC (n = 8,256) from the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia project. Spearman correlations between CRP or AGP and vitamin B-12 or folate concentrations were examined, taking into account complex survey design effects. Results Correlations between inflammation and vitamin B-12 or folate were weak, with no clear pattern of association in either WRA or PSC. Correlation coefficients between CRP and vitamin B-12 for WRA and PSC ranged from −0.25 to 0.16, and correlations between AGP and vitamin B-12 ranged between −0.07 and 0.14. Similarly, correlations between CRP and serum folate ranged from −0.13 to 0.08, and correlations between AGP and serum folate between −0.21 and 0.02. Only 3 surveys measured RBC folate, and among them, correlations for WRA ranged from −0.07 to 0.08 for CRP and −0.04 for AGP (1 country). Conclusions Based on the weak and inconsistent correlations between CRP or AGP and vitamin B-12 or folate biomarkers, there is no rationale to adjust for inflammation when estimating population prevalence of vitamin B-12 or folate deficiencies in WRA or PSC.

scholarly journals VITAMIN D DEFICIENCY;

2012 ◽  
Vol 19 (02) ◽  
pp. 208-213
Author(s):  
MUHAMMAD ASLAM ◽  
ZAHID MASOOD ◽  
Abdul SATTAR ◽  
Maria Qudsia
Keyword(s):  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Sampling Technique ◽  
Reproductive Age ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Vitamin D 3

Objective: To study the Prevalence of Vitamin D deficiency in pregnant women. Study Design: A Cross-sectional analyticalstudy through convenient sampling technique. Setting and duration: At a private Clinic located at East Canal Road Faisalabad, from March2011 to June 2011. Material and method: The study included consecutive 61 pregnant women of reproductive age and non-pregnant womenwere excluded. Blood samples were taken in morning i.e. overnight fasting samples, by venepuncture by disposable syringes sample weretaken and samples were stored at -20 degree centigrade till they were analyzed. Our interest was in age and serum Vitamin D 3 levels. Results:Out of 61 pregnant women results showed that 87.0% pregnant women were having Vitamin D deficiency, 10.0% were having Vitamin Dinsufficiency, 3.0% had Vitamin D sufficiency and none shows Vitamin D intoxication. Vitamin D deficiency was more prevalent in pregnantwomen of younger age group. Furthermore prevalence was higher among the pregnant mothers with high parity. Moreover, 65% women werenot exposed to sunlight properly, 60% women had muscle cramps and bony aches. 90% women never were tested for tested Vitamin D levelsbefore. Conclusions: Prevalence of Vitamin D deficiency is significant in pregnant women. It is also important for its effects on various organsand systems of body as well as on pregnancy and neonate. The different aspects of study led to conclusion to emphasize that Health educationbe imparted to pregnant women and their families in terms of diet, proper sunlight exposure and taking Vitamin D supplements in pregnancy. It isthus recommended to perform Vitamin D levels in every pregnant woman.

scholarly journals Association between Food Behaviour of Pregnant Women and Status of Serum Vitamin B12 and Neonatal Outcome – A Cross-Sectional Study

2019 ◽  
Vol 7 (1-2) ◽  
pp. 84-91
Author(s):  
Rowshan Afrooz ◽  
Lipika Ghosh ◽  
Abul Kalam Md Faruq ◽  
Mitheel Ibna Islam
Keyword(s):  
Birth Weight ◽  
Vitamin B12 ◽  
Pregnant Women ◽  
Serum Vitamin ◽  
Cross Sectional Study ◽  
Normal Serum ◽  
Urban Resident ◽  
Sectional Study ◽  
Cross Sectional ◽  
Low Serum

Background & objective: To find the association between serum vitamin B12 and food behavior of the pregnant women and its influence on perinatal outcome. Methods: This cross-sectional study was conducted in the Department of Obstetrics & Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka between June 2012 to July 2013. A total of 102 uncomplicated pregnant women attending at the Obstetrics & Gynaecology Department of BSMMU, Dhaka were the study population. Plasma vitamin B12 was measured by Abbott Axsym System using a Enzyme Immuno Assay Technique with the blood collected in a plain test tube. A serum vitamin B12 level of < 200 pg/mL was considered as low serum vitamin B12 level. The outcome variables were birth weight, small-for-date, neural tube defects and other congenital malformations. Result: The selected pregnant women were housewife (74.5%) from low socioeconomic strata. They were generally urban resident (90.2%) with mean age being 26.4 years. In terms of education 17.6% were primary level, 30.4% SSC level, 31.4% HSC level and 20.6% graduate and higher level educated. Majority (90.2%) was urban resident with average monthly family income being Taka 29460. One-third (33.3%) was overweight and 6.9% obese. Two-thirds (66.7%) were at 37-39 weeks of gestation and nullipara. More than 60% received ANC (antenatal care) aregularly. Over one-third (35.3%) had low serum vitamin B12 (< 200 pg/mL). The food behaviour of the women was found to be associated with vitamin B12 deficiency. The pregnant women with low serum vitamin B12 (< 200 pg/ml) had significantly lower weekly consumption of fishes and eggs which are the rich source of vitamin B12. The weekly fish, eggs and amount of milk consumed by the pregnant women with low serum vitamin B12 were much lower than those consumed by the pregnant women with normal serum vitamin B12. The pregnant women with low serum vitamin B12 were more likely to carry a higher risk of adverse perinatal outcome. The incidences of low-birth weight and small-for-dates were staggeringly higher in women with low serum vitamin B12 (33.3% and 27.8% respectively) compared to those in women with normal serum vitamin B12. Conclusion: The study concluded that pregnant women with low serum vitamin B12 are accustomed to taking low fish and eggs in their daily diet compared to those who have normal serum vitamin B12. The incidence of low birth weight and small-for-date babies are more prevalent in the pregnant women with subclinical deficiency of vitamin B12. Ibrahim Card Med J 2017; 7 (1&2): 84-91

TO ESTIMATE VITAMIN B LEVEL AND FOLATE IN CHILDREN WITH INFANTILE 12 TREMOR SYNDROME

2021 ◽  
pp. 160-161
Author(s):  
Dinesh Kumar ◽  
Mahesh Kumar Gupta ◽  
Sunil Gothwal ◽  
Umesh Gurjar ◽  
Kailash Kumar Meena ◽  
...  
Keyword(s):  
Hospital Admissions ◽  
Age Groups ◽  
Serum Vitamin ◽  
Serum Folate ◽  
Vitamin B ◽  
Folate Level ◽  
Cross Sectional ◽  
Medical College ◽  
Mother And Child ◽  
The Mean

BACKGROUND- Exact incidence of ITS is not known but it was accounted for 0.2 to 2% pediatric hospital admissions in 1962 and reduced to 0.2% currently in India. Aims of this study to estimate Vitamin B level 12 and folate in children with Infantile Tremor Syndrome METHODS- This Hospital based cross sectional observational study was conducted in, Sir Padampat Mother and Child Health Institute (SPMCHI), SMS Medical College, Jaipur. RESULTS- The mean serum B level was highest in children aged 13-18 months (117.40 pg/ml) and was lowest in children aged 12 6-12 months (67.90 pg/ml). This difference in B level in different age groups was statistically not signicant (p>0.05). The mean 12 serum folate level was highest in children aged 6-12 months (17.32 ng/ml) followed by children aged 13-18 months (15.53 ng/ml) and was lowest in children aged >18 months (13.70 ng/ml). This difference in folate level in different age groups was statistically not signicant (p>0.05). CONCLUSION- Present study ndings suggest that serum vitamin B and folate levels are decreased in children with Infantile 12 Tremor Syndrome.

scholarly journals Associations of Circulating Methylmalonic Acid and Vitamin B-12 Biomarkers Are Modified by Vegan Dietary Pattern in Adult and Elderly Participants of the Adventist Health Study 2 Calibration Study

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Ella H Haddad ◽  
Karen Jaceldo-Siegl ◽  
Keiji Oda ◽  
Gary E Fraser
Keyword(s):  
Dietary Pattern ◽  
Methylmalonic Acid ◽  
Serum Vitamin ◽  
Health Study ◽  
Vitamin B ◽  
Limited Information ◽  
Cross Sectional ◽  
Fortified Food ◽  
Vitamin B 12 ◽  
Adventist Health Study

ABSTRACT Background Elevated plasma methylmalonic acid (MMA) is a functional biomarker of vitamin B-12 status but limited information is available on its prevalence in US vegetarians. Objectives The study examines the prevalence of plasma MMA ≥0.27 µmol/L in those consuming vegetarian diets, its associations with vitamin B-12 intake and biomarkers, and the modifying effect of vegetarian patterns on these associations. Methods In this cross-sectional study (n = 785), concentrations of MMA, vitamin B-12, holotranscobalamin (holoTC), and homocysteine (Hcy) were determined in participants of the calibration substudy of the Adventist Health Study 2 (AHS-2). Vitamin B-12 intake from food, fortified food, and supplements was assessed by six 24-h recalls. Regression models were used to estimate ORs of having high MMA as related to vitamin B-12 status biomarkers, vitamin B-12 intake, and dietary pattern. Results The prevalence of low vitamin B-12 status defined by serum vitamin B-12 &lt;148 pmol/L, holoTC &lt;35 pmol/L, MMA ≥0.27 and ≥0.37 μmol/L, or Hcy ≥15 μmol/L, and the OR of having high MMA did not differ by dietary pattern, possibly due to intake from fortified food and supplements. Total daily vitamin B-12 intake in the second tertile range of 4.4–14.5 μg/d reduced the likelihood of elevated MMA by 69%; and a doubling of vitamin B-12 intake was associated with a 4.3% decrease in plasma MMA. The association between log plasma MMA and biomarkers was modified by diet, with the vegan pattern showing an ∼3-fold stronger association with log serum vitamin B-12 and Hcy than did the nonvegetarian pattern. Conclusions The prevalence of vitamin B-12 intake &lt;2.0 μg/d was 15.2% in vegans, 10.6% in lacto-ovo-vegetarians, and 6.5% in nonvegetarians. Given the irreversible neurological consequences of vitamin B-12 inadequacy, the importance of regular supplemental vitamin B-12 intake in adult and elderly individuals is stressed.

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