Cannabidiol-Mediated Green Synthesis, Characterization, and Cytotoxicity of Metal Nanoparticles in Human Keratinocyte Cells

Nanosized particles, with a size of less than 100 nm, have a wide variety of applications in various fields of nanotechnology and biotechnology, especially in the pharmaceutical industry. Metal nanoparticles [MNPs] have been synthesized by different chemical and physical procedures. Still, the biological approach or green synthesis [phytosynthesis] is considered as a preferred method due to eco-friendliness, nontoxicity, and cost-effective production. Various plants and plant extracts have been used for the green synthesis of MNPs, including biofabrication of noble metals, metal oxides, and bimetallic combinations. Biomolecules and metabolites present in plant extracts cause the reduction of metal ions into nanosized particles by one-step preparation methods. MNPs have remarkable attractiveness in biomedical applications for their use as potential antioxidant, anticancer and antibacterial agents. The present review offers a comprehensive aspect of MNPs production via top-to-bottom and bottom-to-top approach with considerable emphasis on green technology and their possible biomedical applications. The critical parameters governing the MNPs formation by plant-based synthesis are also highlighted in this review.

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Ficus: A Potent Genus in the Green Synthesis of Metal Nanoparticles

International Journal of Pharma and Bio Sciences ◽

10.22376/ijpbs.2020.11.4.p29-36 ◽

2020 ◽

Vol 11 (4) ◽

Author(s):

Naser P. T. N. ◽

Thoppil J. E.

Keyword(s):

Green Synthesis ◽

Metal Nanoparticles

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Nanobiotechnology: Nature-inspired silver nanoparticles towards green synthesis

Energy & Environment ◽

10.1177/0958305x21989883 ◽

2021 ◽

pp. 0958305X2198988

Author(s):

Nur Syakirah Rabiha Rosman ◽

Noor Aniza Harun ◽

Izwandy Idris ◽

Wan Iryani Wan Ismail

Keyword(s):

Electrical Conductivity ◽

Silver Nanoparticles ◽

Green Synthesis ◽

Metal Nanoparticles ◽

Current Trend ◽

Biological Properties ◽

Noble Metal Nanoparticles ◽

Current Application ◽

Physical Chemical ◽

Physical And Chemical

The emergence of technology to produce nanoparticles (1 nm – 100 nm in size) has drawn significant researchers’ interests. Nanoparticles can boost the antimicrobial, catalytic, optical, and electrical conductivity properties, which cannot be achieved by their corresponding bulk. Among other noble metal nanoparticles, silver nanoparticles (AgNPs) have attained a special emphasis in the industry due to their superior physical, chemical, and biological properties, closely linked to their shapes, sizes, and morphologies. Proper knowledge of these NPs is essential to maximise the potential of biosynthesised AgNPs in various applications while mitigating risks to humans and the environment. This paper aims to critically review the global consumption of AgNPs and compare the AgNPs synthesis between conventional methods (physical and chemical) and current trend method (biological). Related work, advantages, and drawbacks are also highlighted. Pertinently, this review extensively discusses the current application of AgNPs in various fields. Lastly, the challenges and prospects of biosynthesised AgNPs, including application safety, oxidation, and stability, commercialisation, and sustainability of resources towards a green environment, were discussed.

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Microwave assisted green synthesis and characterizations of noble metal nanoparticles and their roles as catalysts in organic reduction reactions and anticancer agent

Materials Research Express ◽

10.1088/2053-1591/aaba0c ◽

2018 ◽

Vol 5 (4) ◽

pp. 045032 ◽

Cited By ~ 1

Author(s):

Sijo Francis ◽

Ebey P Koshy ◽

Beena Mathew

Keyword(s):

Green Synthesis ◽

Metal Nanoparticles ◽

Noble Metal ◽

Anticancer Agent ◽

Noble Metal Nanoparticles ◽

Reduction Reactions ◽

Microwave Assisted

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The Multifunctional Roles of Chitosan in the Formation of Flower-Shaped Palladium Nanoparticles

Materials Proceedings ◽

10.3390/iec2m-09256 ◽

2021 ◽

Vol 3 (1) ◽

pp. 18

Author(s):

Thi Tuong Vy Phan

Keyword(s):

Green Synthesis ◽

Metal Nanoparticles ◽

Human Health ◽

Palladium Nanoparticles ◽

Pd Nanoparticles ◽

The Novel ◽

Natural Polymers ◽

Green Method ◽

Harmful Effects

The chemical and physical routes are usually used to synthesize metal nanoparticles. However, the harmful effects on the environment and human health has turned scientists into finding greener methods. We have developed the novel green method for the synthesis of flower Pd nanoparticles based on the chitosan (CS) polymer. In this method, CS can work as a stabilizer, a shape-directing agent, and a size-controllable agent for the synthesis of these nanoparticles. This study provides pioneer evidence about the multifunctional roles of natural polymers in the preparation of metal nanoparticles. Deep and extensive studies should be conducted to explore the great benefits of natural polymers in the green synthesis of metal nanoparticles.

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Application of biosynthesized metal nanoparticles in electrochemical sensors

Journal of the Serbian Chemical Society ◽

10.2298/jsc200521077d ◽

2021 ◽

pp. 77-77

Author(s):

Totka Dodevska ◽

Dobrin Hadzhiev ◽

Ivan Shterev ◽

Yanna Lazarova

Keyword(s):

Green Synthesis ◽

Metal Nanoparticles ◽

Electrochemical Sensors ◽

Dynamic Range ◽

Limit Of Detection ◽

Cost Effective ◽

Electrochemical Sensing ◽

Synthesis Methods ◽

Range Limit ◽

Wide Range

Recently, the development of eco-friendly, cost-effective and reliable methods for synthesis of metal nanoparticles has drawn a considerable attention. The so-called green synthesis, using mild reaction conditions and natural resources as plant extracts and microorganisms, has established as a convenient, sustainable, cheap and environmentally safe approach for synthesis of a wide range of nanomaterials. Over the past decade, biosynthesis is regarded as an important tool for reducing the harmful effects of traditional nanoparticle synthesis methods commonly used in laboratories and industry. This review emphasizes the significance of biosynthesized metal nanoparticles in the field of electrochemical sensing. There is increasing evidence that green synthesis of nanoparticles provides a new direction in designing of cost-effective, highly sensitive and selective electrode-catalysts applicable in food, clinical and environmental analysis. The article is based on 157 references and provided a detailed overview on the main approaches for green synthesis of metal nanoparticles and their applications in designing of electrochemical sensor devices. Important operational characteristics including sensitivity, dynamic range, limit of detection, as well as data on stability and reproducibility of sensors have also been covered. Keywords: biosynthesis; green synthesis; nanomaterials; nanotechnology; modified electrodes

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