Regulation of extracellular matrix production by chemically synthesized subfragments of type I collagen carboxy propeptide

Biochemistry ◽  
1991 ◽  
Vol 30 (29) ◽  
pp. 7097-7104 ◽  
Author(s):  
Kou Katayama ◽  
Jerome M. Seyer ◽  
Rajendra Raghow ◽  
Andrew H. Kang
Keyword(s):  
Extracellular Matrix ◽  
Type I Collagen ◽  
Type I ◽  
Extracellular Matrix Production ◽  
Matrix Production

scholarly journals A pentapeptide from type I procollagen promotes extracellular matrix production

1993 ◽  
Vol 268 (14) ◽  
pp. 9941-9944
Author(s):  
K. Katayama ◽  
J. Armendariz-Borunda ◽  
R. Raghow ◽  
A.H. Kang ◽  
J.M. Seyer
Keyword(s):  
Extracellular Matrix ◽  
Type I ◽  
Type I Procollagen ◽  
Extracellular Matrix Production ◽  
Matrix Production

Effect of HMG-CoA Reductase Inhibition on Vascular Smooth Muscle Cells Extracellular Matrix Production: Role of RhoA

2016 ◽  
Vol 14 (4) ◽  
pp. 345-352 ◽  
Author(s):  
Rogelio Palomino-Morales ◽  
Sonia Perales ◽  
Carolina Torres ◽  
Ana Linares ◽  
Maria J. Alejandre
Keyword(s):  
Extracellular Matrix ◽  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Muscle Cells ◽  
Extracellular Matrix Production ◽  
Matrix Production ◽  
Coa Reductase

scholarly journals The Dynamic Interaction between Extracellular Matrix Remodeling and Breast Tumor Progression

Cells ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1046
Author(s):  
Jorge Martinez ◽  
Patricio C. Smith
Keyword(s):  
Extracellular Matrix ◽  
Type I Collagen ◽  
Cell Metabolism ◽  
Breast Tumors ◽  
Extracellular Matrix Remodeling ◽  
Type I ◽  
Matrix Remodeling ◽  
Desmoplastic Reaction ◽  
The Impact

Desmoplastic tumors correspond to a unique tissue structure characterized by the abnormal deposition of extracellular matrix. Breast tumors are a typical example of this type of lesion, a property that allows its palpation and early detection. Fibrillar type I collagen is a major component of tumor desmoplasia and its accumulation is causally linked to tumor cell survival and metastasis. For many years, the desmoplastic phenomenon was considered to be a reaction and response of the host tissue against tumor cells and, accordingly, designated as “desmoplastic reaction”. This notion has been challenged in the last decades when desmoplastic tissue was detected in breast tissue in the absence of tumor. This finding suggests that desmoplasia is a preexisting condition that stimulates the development of a malignant phenotype. With this perspective, in the present review, we analyze the role of extracellular matrix remodeling in the development of the desmoplastic response. Importantly, during the discussion, we also analyze the impact of obesity and cell metabolism as critical drivers of tissue remodeling during the development of desmoplasia. New knowledge derived from the dynamic remodeling of the extracellular matrix may lead to novel targets of interest for early diagnosis or therapy in the context of breast tumors.

Dynamics of extracellular matrix production and turnover in tissue engineered cardiovascular structures

2001 ◽  
Vol 81 (2) ◽  
pp. 220-228 ◽  
Author(s):  
Ulrich A. Stock ◽  
Dmitri Wiederschain ◽  
Susan M. Kilroy ◽  
Dominique Shum-Tim ◽  
Philip N. Khalil ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Extracellular Matrix Production ◽  
Matrix Production

Glucosamine sulphate does not increase extracellular matrix production at low oxygen tension

2009 ◽  
Vol 337 (1) ◽  
pp. 103-111 ◽  
Author(s):  
Cheng-Juan Qu ◽  
Teemu Pöytäkangas ◽  
Marjo Jauhiainen ◽  
Seppo Auriola ◽  
Mikko J. Lammi
Keyword(s):  
Extracellular Matrix ◽  
Oxygen Tension ◽  
Low Oxygen ◽  
Low Oxygen Tension ◽  
Extracellular Matrix Production ◽  
Glucosamine Sulphate ◽  
Matrix Production

The influence of oxygen concentration on the extracellular matrix production of human nucleus pulposus cells during isolation-expansion process

2017 ◽  
Vol 105 (6) ◽  
pp. 1575-1582 ◽  
Author(s):  
Shu-Hua Yang ◽  
Ming-Hsiao Hu ◽  
Wan-Yu Lo ◽  
Yuan-Hui Sun ◽  
Chang-Chin Wu ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Nucleus Pulposus ◽  
Oxygen Concentration ◽  
Nucleus Pulposus Cells ◽  
Expansion Process ◽  
Extracellular Matrix Production ◽  
Matrix Production

scholarly journals Laminin-5 activates extracellular matrix production and osteogenic gene focusing in human mesenchymal stem cells

2007 ◽  
Vol 26 (2) ◽  
pp. 106-114 ◽  
Author(s):  
Robert F. Klees ◽  
Roman M. Salasznyk ◽  
Scott Vandenberg ◽  
Kristin Bennett ◽  
George E. Plopper
Keyword(s):  
Stem Cells ◽  
Extracellular Matrix ◽  
Mesenchymal Stem Cells ◽  
Human Mesenchymal Stem Cells ◽  
Laminin 5 ◽  
Extracellular Matrix Production ◽  
Matrix Production ◽  
Osteogenic Gene
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