Chemoenzymatic Preparation of Novel Cyclic Imine Sugars and Rapid Biological Activity Evaluation Using Electrospray Mass Spectrometry and Kinetic Analysis

1997 ◽  
Vol 119 (35) ◽  
pp. 8146-8151 ◽  
Author(s):  
Shuichi Takayama ◽  
Richard Martin ◽  
Jiangyue Wu ◽  
Karen Laslo ◽  
Gary Siuzdak ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Biological Activity ◽  
Kinetic Analysis ◽  
Electrospray Mass Spectrometry ◽  
Activity Evaluation

Analysis of Trace Level Perchlorate in Drinking Water and Ground Water by Electrospray Mass Spectrometry

1998 ◽  
Author(s):  
Rebecca A. Clewell ◽  
Wayne T. Brashear ◽  
David T. Tsui ◽  
Sanwat Chaudhuri ◽  
Rachel S. Cassady
Keyword(s):  
Mass Spectrometry ◽  
Drinking Water ◽  
Ground Water ◽  
Electrospray Mass Spectrometry ◽  
Trace Level

Neocryptolepine: A Promising Indoloisoquinoline Alkaloid with Interesting Biological Activity. Evaluation of the Drug and its Most Relevant Analogs

2015 ◽  
Vol 15 (17) ◽  
pp. 1683-1707 ◽  
Author(s):  
Enrique Larghi ◽  
Andrea Bracca ◽  
Abel Arroyo Aguilar ◽  
Daniel Heredia ◽  
Jorgelina Pergomet ◽  
...  
Keyword(s):  
Biological Activity ◽  
Activity Evaluation

scholarly journals The regio-selective synthesis of 10-hydroxy camptothecin norcantharidin conjugates and their biological activity evaluation in vitro

2018 ◽  
Vol 5 (6) ◽  
pp. 172317 ◽  
Author(s):  
Chang K. Zhao ◽  
Chan Li ◽  
Xian H. Wang ◽  
Yu J. Bao ◽  
Fu H. Yang ◽  
...  
Keyword(s):  
Biological Activity ◽  
Cell Growth ◽  
Cancer Treatment ◽  
Cancer Cell ◽  
Therapeutic Potential ◽  
Selective Synthesis ◽  
Cancer Cell Growth ◽  
Activity Evaluation ◽  
Moderate Yield

A series of conjugates of 10-hydroxy camptothecin (HCPT) with functionalized norcantharidin derivatives were regio-selectively synthesized in the condition of (3-dimethylaminopropyl) ethyl-carbodiimide monohydrochloride in a moderate yield. The synthesized conjugate HCPT pro-drugs can also suppress cancer cell growth in vitro . These conjugated pro-drug constructs possess therapeutic potential as novel bi-functional conjugate platforms for cancer treatment.

Determination of the endogenous phosphorylation state of B-50/GAP-43 and neurogranin in different brain regions by electrospray mass spectrometry

FEBS Letters ◽  
1996 ◽  
Vol 389 (3) ◽  
pp. 309-313 ◽  
Author(s):  
Monica Di Luca ◽  
Lucia Pastorino ◽  
Vittorio Raverdino ◽  
Pierre N.E. De Graan ◽  
Antonio Caputi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Mass Spectrometry ◽  
Brain Regions ◽  
Phosphorylation State
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