Determination of the Chemical Composition and Antioxidant Activity of the Essential Oil ofArtemisia dracunculusand of the Antifungal and Antibacterial Activities of TurkishArtemisiaabsinthium,A. dracunculus,Artemisia santonicum, andArtemisia spicigeraEssential Oils

2005 ◽  
Vol 53 (24) ◽  
pp. 9452-9458 ◽  
Author(s):  
Saban Kordali ◽  
Recep Kotan ◽  
Ahmet Mavi ◽  
Ahmet Cakir ◽  
Arzu Ala ◽  
...  
2020 ◽  
Vol 11 (1) ◽  
pp. 7912-7920

The present study was dedicated to the study of the chemical composition and the antioxidant activity of the essential oils from the sawdust of Tetraclinis articulata in Morocco (from Khemisset region). The yield of the essential oil obtained by hydrodistillation from sawdust was 2.19%. The determination of the chemical composition of Tetraclinis articulata essential oils (TAEO) was carried out by GC-SM analysis. The results that 22 volatile compounds were identified in the sawdust part of T. articulata, representing 87.25% of the total composition. The study of TAEO antioxidant activity was assessed by three different methods: the trapping of free radical DPPH, bleaching assay ABTS, and the reduction of iron (FRAP). The results of DPPH test showed that TAEO (IC50=0.0144 mg/mL) has a very interesting antioxidant activity compared to the ascorbic acid used as reference (IC50=0.0184 mg/mL). These results reveal promising prospects for the future exploitation of TAEO as a potential source of natural antioxidant substances that may be used for future investigations.


Agronomy ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 362
Author(s):  
Hamza Zine ◽  
Manar Ibrahimi ◽  
Souad Loqman ◽  
Eleni G. Papazoglou ◽  
Soukaina Ouhaddou ◽  
...  

Atriplex semibaccata R.Br. is a perennial halophyte that has received much attention for studies of revegetation of marginal lands in arid and semi-arid environments. It was, recently, demonstrated that there are no risks in terms of contamination of essential oil (EO) from growing plant on such land. Interest in exploring the antibacterial and antioxidant potential of A. semibaccata EO has consequently been renewed. The objective of this study was to investigate the chemical composition, as well as the antioxidant and antibacterial activities of A. semibaccata EO. The antibacterial activity was evaluated against native (drug-sensitive) and multidrug-resistant (MDR) bacteria by testing the EO alone and in combination with conventional antibiotics. The chemical composition of EO was analyzed by gas chromatography/mass spectrometry, 52 chemical compounds were identified, and 2-Methoxy-4-vinyl phenol (48.9%), benzaldehyde (6.7%), and benzyl alcohol (6.3%) were found to be the main constituents of EO. Furthermore, the antioxidant activity was evaluated using a 2,2-diphenyl-1-picrylhydrazyl reducing–scavenging test. The EO from this species possessed high antioxidant activity (938.65 μg TE/g EO). The antibacterial test demonstrated an inhibitory effect on six native and MDR bacterial strains. We found that Staphylococcus aureus (Gram+), Klebsiella pneumoniae (Gram−), and Escherichia coli (Gram−) were more sensitive than MDR strains, with an inhibition zone ranging from 11.16 mm to 12 mm. Moreover, the minimum inhibitory concentration ranged from 3.12 mg/mL to 6.25 mg/mL. The combination of gentamicin and EO revealed a high synergistic effect. The effect on S. aureus and K. pneumoniae showed lower fractional inhibitory concentration indices of 0.39 and 0.27, respectively. The results also revealed that A. semibaccata EO contained compounds with antibacterial potential against MDR bacteria, with antioxidant properties, and with a moderate synergistic effect in combination with gentamicin. The EO from A. semibaccata could be considered a new and potential source of natural antioxidant and antibacterial agents. These findings make A. semibaccata an excellent choice for the revegetation of marginal lands with the subsequent use of biomass for the production of EO with significant potential in the control of microbial infection.


Author(s):  
Azadeh Foroughi ◽  
Pouya Pournaghi ◽  
Fariba Najafi ◽  
Akram Zangeneh ◽  
Mohammad Mahdi Zangeneh ◽  
...  

Medicinal plants are considered modern resources for producing agents that could act as alternatives to antibiotics in demeanor of antibiotic-resistant bacteria. The aim of the study was to evaluate the chemical composition and antibacterial activities of essential oil of Foeniculum vulgare (FV) against Pseudomonas aeruginosa and Bacillus subtilis. Gas chromatography mass spectrometry was done to specify chemical composion. As a screen test to detect antibacterial properties of the essential oil, agar disk and agar well diffusion methods were employed. Macrobroth tube test was performed to determinate MIC. The results indicated that the most substance found in FV essential oil was Trans-anethole (47.41 %), also the essential oil of FV with 0.007 g/ml concentration has prevented P. aeruginosa and with 0.002 g/ml concentration has prevented B. subtilis from the growth. Thus, the research represents the antibacterial effects of the medical herb on test P. aeruginosa and B. subtilis. We believe that the article provide support to the antibacterial properties of the essential oil. The results indicate the fact that the essential oil from the plant can be useful as medicinal or preservatives composition.


Antioxidants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1081
Author(s):  
Matilda Rădulescu ◽  
Călin Jianu ◽  
Alexandra Teodora Lukinich-Gruia ◽  
Marius Mioc ◽  
Alexandra Mioc ◽  
...  

The investigation aimed to study the in vitro and in silico antioxidant properties of Melissa officinalis subsp. officinalis essential oil (MOEO). The chemical composition of MOEO was determined using GC–MS analysis. Among 36 compounds identified in MOEO, the main were beta-cubebene (27.66%), beta-caryophyllene (27.41%), alpha-cadinene (4.72%), caryophyllene oxide (4.09%), and alpha-cadinol (4.07%), respectively. In vitro antioxidant properties of MOEO have been studied in 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging, and inhibition of β-carotene bleaching assays. The half-maximal inhibitory concentration (IC50) for the radical scavenging abilities of ABTS and DPPH were 1.225 ± 0.011 μg/mL and 14.015 ± 0.027 μg/mL, respectively, demonstrating good antioxidant activity. Moreover, MOEO exhibited a strong inhibitory effect (94.031 ± 0.082%) in the β-carotene bleaching assay by neutralizing hydroperoxides, responsible for the oxidation of highly unsaturated β-carotene. Furthermore, molecular docking showed that the MOEO components could exert an in vitro antioxidant activity through xanthine oxidoreductase inhibition. The most active structures are minor MOEO components (approximately 6%), among which the highest affinity for the target protein belongs to carvacrol.


2019 ◽  
Vol 22 (2) ◽  
pp. 347-355 ◽  
Author(s):  
Larissa Sousa Santos ◽  
Cassia Cristina Fernandes Alves ◽  
Elisângela Barbosa Borges Estevam ◽  
Carlos Henrique Gomes Martins ◽  
Thayná de Souza Silva ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (10) ◽  
pp. 2888
Author(s):  
Carmen M. S. Ambrosio ◽  
Gloria L. Diaz-Arenas ◽  
Leidy P. A. Agudelo ◽  
Elena Stashenko ◽  
Carmen J. Contreras-Castillo ◽  
...  

Essential oils (EOs) from Citrus are the main by-product of Citrus-processing industries. In addition to food/beverage and cosmetic applications, citrus EOs could also potentially be used as an alternative to antibiotics in food-producing animals. A commercial citrus EO—Brazilian Orange Terpenes (BOT)—was fractionated by vacuum fractional distillation to separate BOT into various fractions: F1, F2, F3, and F4. Next, the chemical composition and biological activities of BOT and its fractions were characterized. Results showed the three first fractions had a high relative amount of limonene (≥10.86), even higher than the whole BOT. Conversely, F4 presented a larger relative amount of BOT’s minor compounds (carvone, cis-carveol, trans-carveol, cis-p-Mentha-2,8-dien-1-ol, and trans-p-Mentha-2,8-dien-1-ol) and a very low relative amount of limonene (0.08–0.13). Antibacterial activity results showed F4 was the only fraction exhibiting this activity, which was selective and higher activity on a pathogenic bacterium (E. coli) than on a beneficial bacterium (Lactobacillus sp.). However, F4 activity was lower than BOT. Similarly, F4 displayed the highest antioxidant activity among fractions (equivalent to BOT). These results indicated that probably those minor compounds that detected in F4 would be more involved in conferring the biological activities for this fraction and consequently for the whole BOT, instead of the major compound, limonene, playing this role exclusively.


Heliyon ◽  
2021 ◽  
pp. e07244
Author(s):  
Olubunmi A. Wintola ◽  
Aderonke A. Olajuyigbe ◽  
Anthony J. Afolayan ◽  
Roger M. Coopoosamy ◽  
Olufunmiso O. Olajuyigbe

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