Phenolic Composition of Vinegars over an Accelerated Aging Process Using Different Wood Species (Acacia, Cherry, Chestnut, and Oak): Effect of Wood Toasting

2014 ◽  
Vol 62 (19) ◽  
pp. 4369-4376 ◽  
Author(s):  
Ana B. Cerezo ◽  
M. Antonia Álvarez-Fernández ◽  
Ruth Hornedo-Ortega ◽  
Ana M. Troncoso ◽  
M. Carmen García-Parrilla
Keyword(s):  
Wood Species ◽  
Aging Process ◽  
Accelerated Aging ◽  
Phenolic Composition

scholarly journals Largely accelerated arterial aging in rheumatoid arthritis is associated with inflammatory activity and smoking in the early stage of the disease

2020 ◽  
Author(s):  
Nikolett Mong ◽  
Zoltan Tarjanyi ◽  
Laszlo Tothfalusi ◽  
Andrea Bartykowszki ◽  
Aniko Ilona Nagy ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Cardiovascular Events ◽  
Aging Process ◽  
Reference Group ◽  
Early Stage ◽  
Accelerated Aging ◽  
Contributing Factors ◽  
Atherosclerosis Progression ◽  
Arterial Aging

Abstract Background: Rheumatoid arthritis (RA) patients have a shorter life expectancy than the general population primarily due to cardiovascular comorbidities.Objectives: To characterize arterial aging in RA.Patients and methods: Coronary calcium scores (CCS) were available from 112 RA patients; out of these patients, follow-up CCS were measured of 54 randomly selected individuals. Control CCS were obtained from the MESA database (includes 6000< participants); arterialage was calculated from CCS.Results: RA patients were significantly older (10.45±18.45 years, p<0.001) in terms of the arterial age compared to the age, gender and race matched controls. The proportion of RA patients who had zero CCS was significantly less (p<0.01) than in the MESA reference group. Each disease year contributed an extra 0.395 years (p<0.01) on the top of the normal aging process. However, the rate of the accelerated aging is not uniform, in the first years of the disease it is apparently faster. Smoking (p<0.05), previous cardiovascular events (p<0.05) and high blood pressure (p<0.05) had additional significant effect on the aging process. In the follow-up study, inflammatory disease activity (CRP>5 mg/L, p<0.05) especially in smokers and shorter than 10 years disease duration (p=0.05) had the largest impact.Conclusions: Arterial aging is faster in RA patients compared to control subjects, particularly in the first 10 years of the disease. Inflammation, previous cardiovascular events and smoking are additional contributing factors to the intensified coronary atherosclerosis progression. These data support that optimal control of inflammation is essential to attenuate the cardiovascular risk in RA.

Effect of Accelerated Aging Process on Seed Quality and Biochemical Changes in Sweet Pepper (Capsicum annuum Linn.) Seeds

2011 ◽  
Vol 10 (2) ◽  
pp. 175-182 ◽  
Author(s):  
P. Kaewnaree ◽  
S. Vichitphan ◽  
P. Klanrit ◽  
B. SIRI ◽  
K. Vichitphan
Keyword(s):  
Capsicum Annuum ◽  
Aging Process ◽  
Seed Quality ◽  
Accelerated Aging ◽  
Sweet Pepper ◽  
Biochemical Changes

scholarly journals Physical Property Changes in Plutonium Observed from Accelerated Aging using Pu-238 Enrichment

2006 ◽  
Vol 986 ◽  
Author(s):  
Brandon W. Chung ◽  
Bill Choi ◽  
Cheng Saw ◽  
Stephen Thompson ◽  
Conrad Woods ◽  
...  
Keyword(s):  
Ultimate Strength ◽  
Tensile Property ◽  
Aging Process ◽  
Accelerated Aging ◽  
Physical Property ◽  
Tensile Tests ◽  
Weight Percent ◽  
Volume Increase ◽  
Property Changes ◽  
Weapons Grade Plutonium

AbstractWe present changes in volume, immersion density, and tensile property observed from accelerated aged plutonium alloys. Accelerated alloys (or spiked alloys) are plutonium alloys enriched with approximately 7.5 weight percent of the faster-decaying 238Pu to accelerate the aging process by approximately 17 times the rate of unaged weapons-grade plutonium. After sixty equivalent years of aging on spiked alloys, the dilatometry shows the samples at 35°C have swelled in volume by 0.15 to 0.17 % and now exhibit a near linear volume increase due to helium in-growth. The immersion density of spiked alloys shows decrease in density, similar normalized volumetric changes (expansion) for spiked alloys. Tensile tests show increasing yield and engineering ultimate strength as spiked alloys are aged.

Lamin A-linked progerias: is farnesylation the be all and end all?

2010 ◽  
Vol 38 (1) ◽  
pp. 281-286 ◽  
Author(s):  
Dawn T. Smallwood ◽  
Sue Shackleton
Keyword(s):  
Clinical Trials ◽  
Aging Process ◽  
Gene Mutations ◽  
Accelerated Aging ◽  
Membrane Dynamics ◽  
Lamin A ◽  
Farnesyltransferase Inhibitors ◽  
C Terminus ◽  
Progeria Syndrome ◽  
Hutchinson Gilford Progeria Syndrome

HGPS (Hutchinson–Gilford progeria syndrome) is a severe childhood disorder that appears to mimic an accelerated aging process. The disease is most commonly caused by gene mutations that disrupt the normal post-translational processing of lamin A, a structural component of the nuclear envelope. Impaired processing results in aberrant retention of a farnesyl group at the C-terminus of lamin A, leading to altered membrane dynamics. It has been widely proposed that persistence of the farnesyl moiety is the major factor responsible for the disease, prompting clinical trials of farnesyltransferase inhibitors to prevent lamin A farnesylation in children afflicted with HGPS. Although there is evidence implicating farnesylation in causing some of the cellular defects of HGPS, results of several recent studies suggest that aberrant lamin A farnesylation is not the only determinant of the disease. These findings have important implications for the design of treatments for this devastating disease.

scholarly journals Possible role of tetracyclines on decreasing the accelerated aging process of well-controlled HIV patients on antiretroviral therapy

2015 ◽  
Vol 14 (4) ◽  
pp. 133-137
Author(s):  
Martin Gnoni ◽  
Diana Otero ◽  
Scott Friedstrom ◽  
Steven Blatt ◽  
Julio Ramirez
Keyword(s):  
Antiretroviral Therapy ◽  
Aging Process ◽  
Accelerated Aging ◽  
Hiv Patients

scholarly journals Accelerated aging of bio-oil from lignin conversion in subcritical water

TAPPI Journal ◽  
2017 ◽  
Vol 16 (03) ◽  
pp. 123-141 ◽  
Author(s):  
Huyen Nguyen Lyckeskog ◽  
Cecilia Mattsson ◽  
Lars Olausson ◽  
Sven-Ingvar Andersson ◽  
Lennart Vamling ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Aging Process ◽  
Subcritical Water ◽  
Accelerated Aging ◽  
Weight Fraction ◽  
Hydrothermal Liquefaction ◽  
Bio Oil ◽  
Nuclear Magnetic

Accelerated aging of bio-oil derived from lignin was investigated at different aging temperatures (50°C and 80°C) and times (1 hour, 1 day, 1 week, and 1 month). The bio-oil used was produced by the hydrothermal liquefaction of kraft lignin, using phenol as the capping agent, and base (potassium carbonate and potassium hydroxide) and zirconium dioxide as the catalytic system in subcritical water. Elemental composition, molecular weight (by using gel permeation chromatography), and chemical composition (by using gas chromatography–mass spectrometry and 2D nuclear magnetic resonance [18.8 T, DMSO-d6]) of the bio-oil were measured to gain better understanding of the changes that occurred after being subjected to an accelerated aging process. The ligninderived hydrothermal liquefaction bio-oil was quite stable compared with biomass-pyrolysis bio-oil. The yield of the low molecular weight fraction (light oil) decreased from 64.1% to 58.1% and that of tetrahydrofuran insoluble fraction increased from 16.5% to 22.2% after aging at 80°C for 1 month. Phenol and phenolic dimers (Ar–CH2–Ar) had high reactivity compared with other aromatic substituents (i.e., methoxyl and aldehyde groups); these may participate in the polymerization/condensation reactions in the hydrothermal liquefaction bio-oil during accelerated aging. Moreover, the 2D heteronuclear single quantum coherence nuclear magnetic resonance spectra of the high molecular weight fraction (heavy oil) in the aged raw oil in the aromatic region showed that the structure of this fraction was a combination of phenol-alkyl patterns, and the guaiacol cross-peaks of Ar2, Ar5, and Ar6 after aging indicate that a new polymer was formed during the aging process.

Psychological Stress and Cellular Aging

2017 ◽  
Author(s):  
Idan Shalev ◽  
Waylon J. Hastings
Keyword(s):  
Stress Response ◽  
Aging Process ◽  
Physiological Activity ◽  
Accelerated Aging ◽  
Cellular Level ◽  
Cellular Aging ◽  
Biological Stress ◽  
Short Term Exposure ◽  
Chronic Stressors ◽  
Different Types

Stress is a multistage process during which an organism perceives, interprets, and responds to threatening environmental stimuli. Physiological activity in the nervous, endocrine, and immune systems mediates the biological stress response. Although the stress response is adaptive in the short term, exposure to severe or chronic stressors dysregulates these biological systems, promoting maladaptive physiology and an accelerated aging phenotype, including aging on the cellular level. Two structures implicated in this process of stress and cellular aging are telomeres, whose length progressively decreases with age, and mitochondria, whose respiratory activity becomes increasingly inefficient with advanced age. Stress in its various forms is suggested to influence the maintenance and stability of these structures throughout life. Elucidating the interrelated connection between telomeres and mitochondria and how different types of stressors are influencing these structures to drive the aging process is of great interest. A better understanding of this subject can inform clinical treatments and intervention efforts to reduce (or even reverse) the damaging effects of stress on the aging process.

Accelerated Aging Tests of HTPB-Based Propellants

2018 ◽  
pp. 246-271
Author(s):  
Roberta Jachura Rocha
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Crosslink Density ◽  
Aging Process ◽  
Low Cost ◽  
Accelerated Aging ◽  
Solid Propellants ◽  
Launch Vehicles ◽  
Late Twentieth ◽  
Late Twentieth Century

In the late twentieth century, liquid and solid propulsion technologies have been integrated into hybrid engines currently apllied in propulsion launch vehicles and missiles. The reaction of polyol (HTPB) and diisocyanate (IPDI) provides the most versatile of the binders in the production of solid propellants due to its ability to withstand high loads combined with low cost and ease of processing. A propellant based on HTPB obtained in this study was submitted to natural and accelerated aging tests, seeking to evaluate the modifications of mechanical properties as tensile strength, elongation and hardness up to 360 days. The mechanism considered in the aging process is the increase of crosslink density by breaking the double bond contained in the HTPB molecule, which causes the instability of the propellant, increasing its handling risk. Samples of these propellants subjected to aging presented variations in their properties that match the values available in the literature.

Evolution of phenolic composition and sensory properties in red wine aged in contact with Portuguese and French oak wood chips

OENO One ◽  
2006 ◽  
Vol 40 (1) ◽  
pp. 25 ◽  
Author(s):  
G. De Coninck ◽  
António Manuel Jordão ◽  
Jorge Manuel Ricardo-da-Silva ◽  
Olga Laureano
Keyword(s):  
Wood Species ◽  
Red Wine ◽  
Wood Chip ◽  
Quercus Petraea ◽  
Sensory Properties ◽  
Wood Chips ◽  
Taste Intensity ◽  
Quercus Pyrenaica ◽  
Phenolic Composition ◽  
Oak Wood

<p style="text-align: justify;">A red wine was matured in contact with 4 g/L of oak wood chips from Portuguese (Quercus pyrenaica Willd.), French (Quercus petraea L.) and a mixture (50:50) of this two oak wood species, during 13 weeks, in order to evaluate the effects of these different oak wood chip species (specially Portuguese oak wood) on the phenolic composition evolution of the wine and in their sensory properties. In general, for the phenolic compounds studied, it wasn't possible to detect remarkable differences between the control wine (aged without oak wood chips) and the wines aged in contact with the two oak wood chips species used. However, for non-flavonoid phenols, the presence of oak wood chips contributed to an increase of these compounds in red wines. The influence of oak wood chips in anthocyanins evolution were similar for all wines, except for malvidin-3-glucoside, which decrease was more evident for the wine aged in contact with oak wood chips. The oak wood chips species and the chips concentration used in this study, didn't affect the proanthocyanidin contents in the wines during the time considered.</p><p style="text-align: justify;">Sensory results showed that, the wines aged in contact with Portuguese and French oak wood chips and the mixture of this two oak wood species, differed significantly from the control wine in several sensorial characteristics. The wines aged in contact with wood chips showed a higher punctuation values for intensity, toasted, wood and vanillin aroma, taste intensity and global appreciation. This positive effect was more evident for wines aged with Portuguese oak wood chips. Probably this results, suggest that the Portuguese oak wood samples species (Quercus pyrenaica Willd.) used could be considered suitable for barrel production because it has a positively effect in sensorial red wine attributes. Thus with this study we tried to contribute for understand the Portuguese oak wood role in red wine characteristics.</p>

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