Supplementation with Riboflavin (Vitamin B2) for Migraine Prophylaxis in Adults and Children: A Review

2015 ◽  
Vol 85 (1-2) ◽  
pp. 79-87 ◽  
Author(s):  
Nazli Namazi ◽  
Javad Heshmati ◽  
Ali Tarighat-Esfanjani
Keyword(s):  
Side Effects ◽  
Key Words ◽  
English Language ◽  
Migraine Prophylaxis ◽  
Vitamin B ◽  
Vitamin B2 ◽  
Insufficient Evidence ◽  
Positive Role ◽  
Migraine Pathogenesis ◽  
Adults And Children

Abstract. Background and Aim: Migraine is a unilateral and pulsating headache associated with nausea, photophobia, vomiting, and sensitivity to light. Low vitamin B2 can lead to mitochondrial dysfunction and may have an effect on migraine pathogenesis. The aim of the present study was to carry out a review of existing evidence regarding the effects of riboflavin (vitamin B2) supplementation on migraine prophylaxis in adults and children. Material and Methods: We searched the databases of PubMed, Science Direct, Google Scholar, and Springer between 1990 and December 2013. Key words included vitamin B2, riboflavin, migraine, vomiting headache, and prevention. We limited our search to human studies in the English language. Review articles and abstracts from symposiums and conferences were excluded. Results: Finally, eleven eligible articles were found: seven involved studies with adults and four involved studies with children. The results indicated that supplementation with vitamin B2 in adults can play a positive role in reducing the frequency and duration of migraine attacks with no serious side effects. Conclusions: It seems that riboflavin is a safe and well-tolerated option for preventing migraine symptoms in adults, however, there is insufficient evidence to make recommendations regarding vitamin B2 as an adjunct therapy in adults and children with migraine.

scholarly journals What Is the Evidence that Riboflavin Can Be Used for Migraine Prophylaxis?

2016 ◽  
Vol 27 (1) ◽  
pp. 7 ◽  
Author(s):  
Tracey N. Liebman ◽  
Sara C. Crystal
Keyword(s):  
Side Effects ◽  
Adverse Effects ◽  
Mitochondrial Dysfunction ◽  
Symptomatic Treatment ◽  
Oxygen Metabolism ◽  
Migraine Prophylaxis ◽  
Vitamin B2 ◽  
Double Blind ◽  
Prophylactic Agent

Individuals with migraine often have recurrent, painful symptoms, and symptomatic treatments have detrimentalside effects and do not prevent further attacks. Studies indicate that riboflavin can be used to decrease headachefrequency and lessen the need for symptomatic treatment. Mitochondrial dysfunction may play a role in migrainepathogenesis by interfering with oxygen metabolism. Daily doses of riboflavin, vitamin B2, may improve mitochondrialfunction by increasing the reserve of brain mitochondrial energy, and there are minimal side effects with dailytreatment. However, there is a need for further randomized, double-blind controlled studies to determine the effectivedose. Although riboflavin may not fully eliminate migraine nor take effect for several months, riboflavin is apromising prophylactic agent with minimal adverse effects that may significantly reduce the frequency of migraine.

The Impact of Anglicizing Former German-Language Psychology Journals on Authorship and Citation Frequencies

2012 ◽  
Vol 17 (3) ◽  
pp. 190-198 ◽  
Author(s):  
Günter Krampen ◽  
Thomas Huckert ◽  
Gabriel Schui
Keyword(s):  
Side Effects ◽  
English Language ◽  
General Trend ◽  
Native Language ◽  
Impact Factors ◽  
German Language ◽  
Journal Articles ◽  
Number Of Citations ◽  
The Impact ◽  
Number Of Authors

Exemplary for other than English-language psychology journals, the impact of recent Anglicization of five former German-language psychology journals on (1) authorship (nationality, i.e., native language, and number of authors, i.e., single or multiple authorships), (2) formal characteristics of the journal (number of articles per volume and length of articles), and (3) number of citations of the articles in other journal articles, the language of the citing publications, and the impact factors (IF) is analyzed. Scientometric data on these variables are gathered for all articles published in the four years before anglicizing and in the four years after anglicizing the same journal. Results reveal rather quick changes: Citations per year since original articles’ publication increase significantly, and the IF of the journals go up markedly. Frequencies of citing in German-language journals decrease, citing in English-language journals increase significantly after the Anglicization of former German-language psychology journals, and there is a general trend of increasing citations in other languages as well. Side effects of anglicizing former German-language psychology journals include the publication of shorter papers, their availability to a more international authorship, and a slight, but significant increase in multiple authorships.

Means Of Reproduction Of Communicative Semantics In Synchronous Translation Of English-Language And Chinese-Language Economic And Political Texts In Ukrainian

2019 ◽  
Vol 26 (27) ◽  
pp. 30-41
Author(s):  
Maryna Baklanova ◽  
Oleksandra Popova
Keyword(s):  
Key Words ◽  
English Language ◽  
Chinese Language ◽  
Time Frame ◽  
Contrastive Analysis ◽  
Linguistic Features ◽  
Simultaneous Translation

This article is devoted to the problem dealing with the reproduction of communicative semantics while translating English, Chinese economic and political texts into Ukrainian. The content and structure of simultaneous translation were analysed. A contrastive analysis of the linguistic features of the English, Chinese and Ukrainian communicative semantics was made. Some tactics enabling the reproduction of the texts under research into the Ukrainian language within simultaneous translation were specified. Key words: simultaneous translation, transformations, the Chinese language, the English language, the Ukrainian language, speech tempo, time frame.

EFFECTS OF “HOE HOA TAN II” REMEDY IN THE TREATMENT OF INTERNAL HAEMORROHIDS GRADE I, II AND III

2015 ◽  
pp. 80-85
Author(s):  
Van Anh Nguyen ◽  
Van Nhan Le ◽  
Nguyen Nhu Phuong Phan
Keyword(s):  
Side Effects ◽  
Key Words ◽  
Patient Group ◽  
Controlled Study ◽  
Therapeutic Effects ◽  
Radix Angelicae Sinensis ◽  
Randomised Controlled Study ◽  
Citrus Deliciosa ◽  
Randomised Controlled ◽  
Angelicae Sinensis

Objectives: To investigate and evaluate the therapeutic effects of Hoe hoa tan II in the treatment of internal haemorroids grade I, II and III. Ingredients of the remedy include: Hoe Hoa (Styphonolonium japonicum), Chi xac (Fructus citri Aurantii), Hau phac (Magnolia offinalis), Tran bi (Citrus deliciosa Tenore), Thuong thuat (Atractylodes lancea), O mai (Armeniaca vulgaris Lamk), Cam thao (Clycyrrhiza uralensis), Duong quy (Radix Angelicae Sinensis). Subjects and methods: Randomised controlled study (RCT) has been conducted on 60 patients which were divided into two groups, i.e. the first 30 patient group were treated with Hoe hoa tan II remedy 20 g, and the second 30 patient group were treated with Daflon 500 mg in the course of 14 days. Results: Study showed that Hoe hoa tan II has helped improve symptoms of internal haemorroids grade I, II and III such as bleeding, anal exudation, pain, reducing the size of the haemorroid tissues. The remedy has been shown to have the most significant effect on relieving constipation which is typical in haemorroids. The study also revealed no unwanted effects caused by this formula. Conclusion: Hoe hoa tan II can be therapeutically used to treat internal haemorroids grade I, II and III without causing any serious side effects. Key words: Hoe hoa tan II, internal haemorroids grade I, II, III.

EFFICACY OF TENOFOVIR IN PATIENTS OF HBV-RELATED CIRRHOSIS

2016 ◽  
pp. 25-29
Author(s):  
Van Huy Tran ◽  
Thi Huyen Thuong Nguyen
Keyword(s):  
Side Effects ◽  
Serum Creatinine ◽  
Key Words ◽  
Tenofovir Disoproxil Fumarate ◽  
Hbv Dna ◽  
Treatment Side Effects ◽  
Background Data ◽  
Key Words Cirrhosis

Background: Data about efficacy of Tenofovir in patients of HBV –related cirrhosis in Vietnam was still limited. This study is aimed at: - evaluating the clinical, biochemical, virological and Child-Pugh score responses 3,6,9 months after Tenofovir therapy; - assessing possible side effects of tenofovir. Patients and methods: 40 patients with HBV-related cirrhosis were enrolled. All has received Tenofovir disoproxil fumarate 300mg/day. Follow-up after 3,6 and 9 months. Results: Anorexia, oedema and ascites were significantly improved after treatment. HBV DNA became undetectable in 92.5%, 94.55 and 100% after 3,6 and 9 months, respectively. Child- Pugh score was improved after treatment (5.94±0.22 after treatment vs 7.47±0.28 before treatment). Side effects were minors (nausea, vomiting). No case of increase in serum creatinine was found. Conclusion: Tenofovir showed effective and safe in patients of HBV-related cirrhosis. Key words: Cirrhosis, tenofovir, HBV. Key words: cirrhosis, tenofovir, HBV

Use hormonal contraception in women with overweight

2017 ◽  
pp. 120-122
Author(s):  
N.V. Avramenko ◽  
◽  
I.B. Gridina ◽  
Keyword(s):  
Side Effects ◽  
Reproductive Health ◽  
Key Words ◽  
Mucous Membrane ◽  
Clinical Supervision ◽  
Hormonal Contraception ◽  
Negative Influence ◽  
Modern Medicine ◽  
Excessive Weight ◽  
Important Direction

Maintenance of reproductive health and decision of problem of safe contraception women with excessive weight have the issue of the day of present time and it is confessed by important direction of modern medicine. The objective: to define influence of hormonal contraception on the mucous membrane of neck of uterus for women with surplus mass of body. Patients and methods. In 90 women with excessive weight influence of hormonal contraception is studied on the mucous membrane of neck of uterus. Results. It is set that a modern hormonal contraception does not have a negative influence on the state of mucous membrane of neck of uterus for women with surplus mass of body. Conclusion. Women with excessive weight and can effectively and safely to use a modern hormonal contraception. But it is necessary to carry out a clinical supervision for the step of that additional elucidations are possible about the features of application of hormonal contraception for patients with excessive mass of body. Key words: contraception, overweight, side effects.

Reducing pain in certain forms of obstetric pathology: nonsteroidal anti-inflammatory drugs (Сlinical lecture)

2017 ◽  
pp. 9-14
Author(s):  
L. Nazarenko ◽  
Keyword(s):  
Preterm Birth ◽  
Side Effects ◽  
Key Words ◽  
Clinical Efficacy ◽  
Premature Birth ◽  
Pain Syndrome ◽  
Inflammatory Drug ◽  
Threatened Abortion ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

The article discusses the pathogenetic basis for the use of non-steroidal anti-inflammatory drugs (NSPVP) in obstetric practice for the treatment of pain syndrome in women with threatened abortion and pathological preliminary period. Provided with modern views on the mechanisms of analgesic clinical efficacy, side effects NSPVP. Provides information about the place of NSPVP during pregnancy, the risks to the fetus, the positive aspects in the conduct of women at risk of preterm birth, the pathological preliminary period. Key words: nonsteroidal anti-inflammatory drug, pain, premature birth, preliminary period.

LASER 532-NM ND:YAG PICOSECOND IN TREATMENT OF SOLAR LENTIGO AND EPHELIDES

2020 ◽  
pp. 72-77
Author(s):  
Ha Bui Manh ◽  
Thanh Le Thai Van
Keyword(s):  
Side Effects ◽  
Key Words ◽  
Descriptive Study ◽  
Patient Evaluation ◽  
High Efficacy ◽  
Mild Pain ◽  
Solar Lentigo ◽  
Pre Treatment ◽  
532 Nm

Aims: To evaluate the efficacy, side effects of laser 532-nm Nd:YAG picosecond in treating solar lentigo and ephelides at HCMC hospital of dermato-venereology. Objectives and Method: Prospective - descriptive study. There were 43 patients dealing with solar lentigo and ephelides treated with laser 532-nm Nd:YAG picosecond. Each patient went through 3 treatments with one month interval, three months follow up for delayed side effects and recurrent. Evaluating the treatment by MI, VLCS, self-patient evaluation with 5 grades scale. Evaluating side effects of the treatment by 5 grade Wong-Baker scale. Collected data were analysed with SPSS.20.0. Results: Based on MI at the end of the study, the effectiveness of the treatment gained 81.4% good, 16.3% average and 2.3% bad. Self-patient evaluation revealed 76.7% good, 20.9% average and 2.3% bad. VLCS of post-treatment reduced 7.44 ± 2.14 unit compares with of pre-treatment. Recently after treatment, 100% patients had erythema and mild pain in 5 grade Wong-Baker scale, 20.9% had mild edema, 2.3% had post imflammatory hyperpigmentation (PIH). Two ephelides cases recurred 3 months after treatment (4.6%). Conclusions: Laser 523-nm Nd:YAG picosecond has high efficacy and less side effects in treating solar lentigo and ephelides. Key words: solar lentigo, ephelides, laser 532-nm Nd:YAG picosecond

Changes in the organ of vision in children and adults with confirmed COVID-19 and anti-epidemic measures

2021 ◽  
pp. 44-53
Author(s):  
V.V. Brzheskiy ◽  
◽  
O.A. Konikova ◽  
N.N. Sadovnikova ◽  
E.L. Efimova ◽  
...  
Keyword(s):  
Side Effects ◽  
Key Words ◽  
Dry Eye ◽  
Personal Protective Equipment ◽  
Protective Equipment ◽  
Symptomatic Therapy ◽  
Medical Work ◽  
Medical Department ◽  
Ocular Manifestations ◽  
Acute Conjunctivitis

The COVID-19 pandemic revealed several aspects of the problems directly related to the Ophthalmologists: damage to the eyes of patients with the SARS-CoV-2 virus; organization of medical work in a pandemic, including in a medical department redesigned to treat patients infected with SARS-CoV-2; side effects of personal protective equipment usage and anti-epidemic measures aimed to protect the organ of vision. Ocular manifestations were noted in 15–23% of children and 4–31% of adults with COVID-19. They were usually limited to acute conjunctivitis with «clear» discharge, hyperemia, edema and folliculosis of the conjunctiva, which reduced in 7–14 days without any treatment or on symptomatic therapy. The presence of SARS-CoV-2 in the tear and epithelium of the conjunctiva does not always correlated with the presence and severity of conjunctivitis and therefore had no clinical significance. There were also other problems associated with anti-epidemic measures (dry eye syndrome when wearing personal protective equipment, computer visual syndrome, etc.), which also requires attention of Ophthalmologists. Key words: COVID-19, SARS-CoV-2, ocular manifestations in children and adults.

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