scholarly journals High animal protein intake linked to long-term weight gain

2011 ◽  
Vol 8 (2) ◽  
pp. 66-66
Author(s):  
Rachel Thompson
Keyword(s):  
Weight Gain ◽  
Protein Intake ◽  
Animal Protein ◽  
High Animal

Long-term high animal protein diet reduces body weight gain and insulin secretion in diet-induced obese rats

2012 ◽  
Vol 92 (13) ◽  
pp. 2638-2643 ◽  
Author(s):  
Haiyan Chen ◽  
Yiling Wang ◽  
Lichuan Ma ◽  
Jiajun Zhao ◽  
Yinyin Li ◽  
...  
Keyword(s):  
Body Weight ◽  
Insulin Secretion ◽  
Weight Gain ◽  
Body Weight Gain ◽  
Animal Protein ◽  
Protein Diet ◽  
High Animal ◽  
Obese Rats

scholarly journals Biochemical and histological assessment of Alkali therapy during high animal protein intake in the rat

Bone ◽  
2009 ◽  
Vol 45 (5) ◽  
pp. 1004-1009 ◽  
Author(s):  
Joseph E. Zerwekh ◽  
Lixian Zou ◽  
Charles Y.C. Pak ◽  
Orson W. Moe ◽  
Patricia A. Preisig
Keyword(s):  
Protein Intake ◽  
Animal Protein ◽  
High Animal ◽  
Histological Assessment ◽  
Alkali Therapy

scholarly journals Diet and Chronic Kidney Disease

2019 ◽  
Vol 10 (Supplement_4) ◽  
pp. S367-S379 ◽  
Author(s):  
Holly Kramer
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Protein Intake ◽  
Fruits And Vegetables ◽  
Disease Incidence ◽  
Normal Serum ◽  
Western Diet ◽  
Animal Protein ◽  
Ammonium Excretion ◽  
High Animal

ABSTRACT Kidney disease affects almost 15% of the US population, and prevalence is anticipated to grow as the population ages and the obesity epidemic continues due to Western dietary practices. The densely caloric Western diet, characterized by high animal protein and low fruit and vegetable content, has fueled the growth of chronic diseases, including chronic kidney disease. The glomerulus or filtering unit of the kidney is very susceptible to barotrauma, and diets high in animal protein impede the glomerulus’ ability to protect itself from hemodynamic injury. High animal protein intake combined with low intake of fruits and vegetables also leads to a high net endogenous acid production requiring augmentation of ammonium excretion in order to prevent acidosis. This higher workload of the kidney to maintain a normal serum bicarbonate level may further exacerbate kidney disease progression. This article reviews the potential mechanisms whereby several key characteristics of the typical Western diet may impact kidney disease incidence and progression. Reducing animal protein intake and egg yolk and increasing intake of fruits and vegetables and fiber may prevent or delay end-stage renal disease, but few clinical trials have examined vegetarian diets for management of chronic kidney disease. More research is needed to determine optimal dietary patterns for the prevention of kidney disease and its progression.

scholarly journals The Effects of High-Protein Diets on Kidney Health and Longevity

2020 ◽  
Vol 31 (8) ◽  
pp. 1667-1679 ◽  
Author(s):  
Gang-Jee Ko ◽  
Connie M. Rhee ◽  
Kamyar Kalantar-Zadeh ◽  
Shivam Joshi
Keyword(s):  
Dietary Protein ◽  
Protein Intake ◽  
Observational Studies ◽  
Animal Protein ◽  
High Protein ◽  
High Protein Intake ◽  
High Protein Diets ◽  
Protein Diets ◽  
Kidney Health

Although high-protein diets continue to be popular for weight loss and type 2 diabetes, evidence suggests that worsening renal function may occur in individuals with—and perhaps without—impaired kidney function. High dietary protein intake can cause intraglomerular hypertension, which may result in kidney hyperfiltration, glomerular injury, and proteinuria. It is possible that long-term high protein intake may lead to de novo CKD. The quality of dietary protein may also play a role in kidney health. Compared with protein from plant sources, animal protein has been associated with an increased risk of ESKD in several observational studies, including the Singapore Chinese Health Study. Potential mediators of kidney damage from animal protein include dietary acid load, phosphate content, gut microbiome dysbiosis, and resultant inflammation. In light of such findings, adopting current dietary approaches that include a high proportion of protein for weight reduction or glycemic control should be considered with care in those at high risk for kidney disease. Given the possibility of residual confounding within some observational studies and the conflicting evidence from previous trials, long-term studies including those with large sample sizes are warranted to better ascertain the effects of high protein intake on kidney health.

Abstract MP55: Protein Intake is Associated With Lower Risk of Type 2 Diabetes in the Framingham Offspring Study

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Richard T Pickering ◽  
Mengjie Yuan ◽  
Martha R Singer ◽  
Laura Lara Castor ◽  
Lynn L Moore
Keyword(s):  
Physical Activity ◽  
Type 2 Diabetes ◽  
Dietary Protein ◽  
Protein Intake ◽  
Animal Protein ◽  
Plant Protein ◽  
Men And Women ◽  
Beneficial Effects

Introduction: Diet and exercise are key prevention strategies for type 2 diabetes (T2DM). Few longitudinal studies have examined separate effects of animal and plant proteins on T2DM risk and results are conflicting. The goal of this study was to evaluate the association between usual intake of dietary protein (total, animal, and plant) and T2DM risk. Methods: Data from middle-aged men and women in the longitudinal Framingham Offspring Study (FOS) with approximately 20 years of follow-up were used. Diet was assessed using three-day diet records (exams 3 and 5); protein intake was adjusted for body weight using the residuals from a linear regression model. Glucose was measured after an overnight fast; impaired fasting glucose (IFG) was defined as a FG >100; diabetes was diagnosed using a standardized and validated FOS protocol. To estimate the hazards ratios) (HR) for IFG or T2DM, Cox proportional hazards models were used to adjust for confounding by age, sex, education level, physical activity, cigarette smoking, height, energy intake, and weight-adjusted carbohydrate intake. Results: Subjects with the highest total protein intakes (≥100 g, men, ≥90 g women) had 34% reduced risks of IFG/T2DM (HR: 0.66; 95% CI: 0.51, 0.85). In this cohort, intakes of animal protein were more than double those of plant protein. The highest intakes of animal protein (≥65 g, men; ≥55 g, women) vs. lower intakes (<55 g, men; <40 g, women) were linked with 33% reduced risks of IFG/T2DM (95% CI: 0.55, 0.82) while intermediate levels of intake were linked with 29% lower risks. In contrast, moderate and higher intakes of plant protein (20-25 g and ≥25 g vs. <20 g) led to non-statistically significant 6-12% risk reductions. Beneficial effects of total protein were stronger for women (HR: 0.53; 95% CI: 0.36, 0.80) than for men (HR: 0.80; 95% CI 0.57, 1.13). In secondary analyses, we evaluated effect modification by other dietary and lifestyle factors. In particular, both men and women with higher intakes of protein and higher levels of physical activity had statistically significant reductions in long-term risk of IFG/T2DM (31%, 39%, and 22% risk reductions among active adults with higher intakes of total, animal, and plant protein, respectively) compared with more sedentary adults who had lower intakes of protein. In contrast, higher physical activity levels alone (among those with lower protein intakes) were associated with non-statistically significant 13-14% lower risks of IFG/T2DM. Conclusions: This prospective study of middle-aged men and women provides important evidence to suggest that dietary protein when combined with an active lifestyle, may be a strategy for lowering long-term risk of diabetes. In this study, animal protein had stronger beneficial effects, but future studies are needed in population groups with higher intakes of plant protein to determine whether these effects would be comparable.

Are low ultraviolet B and high animal protein intake associated with risk of renal cancer?

2006 ◽  
Vol 119 (11) ◽  
pp. 2705-2709 ◽  
Author(s):  
Sharif B. Mohr ◽  
Edward D. Gorham ◽  
Cedric F. Garland ◽  
William B. Grant ◽  
Frank C. Garland
Keyword(s):  
Renal Cancer ◽  
Protein Intake ◽  
Animal Protein ◽  
Ultraviolet B ◽  
High Animal

High animal protein diet and gut microbiota in human health

2021 ◽  
pp. 1-13
Author(s):  
Jie Cai ◽  
Zhongxu Chen ◽  
Wei Wu ◽  
Qinlu Lin ◽  
Ying Liang
Keyword(s):  
Gut Microbiota ◽  
Human Health ◽  
Animal Protein ◽  
Protein Diet ◽  
High Animal
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