scholarly journals High-resolution two-photon polymerization: the most versatile technique for the fabrication of microneedle arrays

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Zahra Faraji Rad ◽  
Philip D. Prewett ◽  
Graham J. Davies
Keyword(s):  
Additive Manufacturing ◽  
Computer Aided Design ◽  
Fused Deposition Modeling ◽  
Three Dimensional ◽  
Manufacturing Processes ◽  
Two Photon ◽  
Fused Deposition ◽  
Cad Models ◽  
Microneedle Arrays ◽  
Two Photon Polymerization

AbstractMicroneedle patches have received much interest in the last two decades as drug/vaccine delivery or fluid sampling systems for diagnostic and monitoring purposes. Microneedles are manufactured using a variety of additive and subtractive micromanufacturing techniques. In the last decade, much attention has been paid to using additive manufacturing techniques in both research and industry, such as 3D printing, fused deposition modeling, inkjet printing, and two-photon polymerization (2PP), with 2PP being the most flexible method for the fabrication of microneedle arrays. 2PP is one of the most versatile and precise additive manufacturing processes, which enables the fabrication of arbitrary three-dimensional (3D) prototypes directly from computer-aided-design (CAD) models with a resolution down to 100 nm. Due to its unprecedented flexibility and high spatial resolution, the use of this technology has been widespread for the fabrication of bio-microdevices and bio-nanodevices such as microneedles and microfluidic devices. This is a pioneering transformative technology that facilitates the fabrication of complex miniaturized structures that cannot be fabricated with established multistep manufacturing methods such as injection molding, photolithography, and etching. Thus, microstructures are designed according to structural and fluid dynamics considerations rather than the manufacturing constraints imposed by methods such as machining or etching processes. This article presents the fundamentals of 2PP and the recent development of microneedle array fabrication through 2PP as a precise and unique method for the manufacture of microstructures, which may overcome the shortcomings of conventional manufacturing processes.

An Algorithm for Generating 3D Lattice Structures Suitable for Printing on a Multi-Plane FDM Printing Platform

2018 ◽  
Author(s):  
Ismayuzri B. Ishak ◽  
Mark B. Moffett ◽  
Pierre Larochelle
Keyword(s):  
Additive Manufacturing ◽  
Fused Deposition Modeling ◽  
Lattice Structure ◽  
Geometric Model ◽  
Three Dimensional ◽  
Manufacturing Processes ◽  
Lattice Structures ◽  
Fused Deposition ◽  
Structure Generator ◽  
Conventional Machining

Manufacturing processes for the fabrication of complex geometries involve multi-step processes when using conventional machining techniques with material removal processes. Additive manufacturing processes give leverage for fabricating complex geometric structures compared to conventional machining. The capability to fabricate 3D lattice structures is a key additive manufacturing characteristic. Most conventional additive manufacturing processes involve layer based curing or deposition to produce a three-dimensional model. In this paper, a three-dimensional lattice structure generator for multi-plane fused deposition modeling printing was explored. A toolpath for an input geometric model with an overhang structure was able to be generated. The input geometric model was able to be printed using a six degree of freedom robot arm platform. Experimental results show the achievable capabilities of the 3D lattice structure generator for use with the multi-plane platform.

Animal orthosis fabrication with additive manufacturing – a case study of custom orthosis for chicken

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Wiktoria Maria Wojnarowska ◽  
Jakub Najowicz ◽  
Tomasz Piecuch ◽  
Michał Sochacki ◽  
Dawid Pijanka ◽  
...  
Keyword(s):  
Veterinary Medicine ◽  
Additive Manufacturing ◽  
Computer Aided Design ◽  
Three Dimensional ◽  
Fused Deposition Modelling ◽  
Content Type ◽  
Fused Deposition ◽  
Secondary Objective ◽  
Traditional Manufacturing ◽  
Aided Design

Purpose Chicken orthoses that cover the ankle joint area are not commercially available. Therefore, the main purpose of this study is to fabricate a customised temporary Ankle–Foot Orthosis (AFO) for a chicken with a twisted ankle using computer-aided design (CAD) and three-dimensional (3D) printing. The secondary objective of the paper is to present the specific application of Additive Manufacturing (AM) in veterinary medicine. Design/methodology/approach The design process was based on multiple sketches, photos and measurements that were provided by the owner of the animal. The 3D model of the orthosis was made with Autodesk Fusion 360, while the prototype was fabricated using fused deposition modelling (FDM). Evaluation of the AFO was performed using the finite element method. Findings The work resulted in a functional 3D printed AFO for chicken. It was found that the orthosis made with AM provides satisfactory stiffen and a good fit. It was concluded that AM is suitable for custom bird AFO fabrication and, in some respects, is superior to traditional manufacturing methods. It was also concluded that the presented procedure can be applied in other veterinary cases and to other animal species and other parts of their body. AM provides veterinary with a powerful tool for the production of well-fitted and durable orthoses for animals. Research limitations/implications The study does not include the chicken's opinion on the comfort or fit of the manufactured AFO due to communication issues. Evaluation of the final prototype was done by the researchers and the animal owner. Originality/value No evidence was found in the literature on the use of AM for chicken orthosis, so this study is the first to describe such an application of AM. In addition, the study demonstrates the value of AM in veterinary medicine, especially in the production of devices such as orthoses.

Carbon Nanotube Reinforced Fused Deposition Modeling Using Microwave Irradiation

2016 ◽  
Author(s):  
Meng Zhang ◽  
Xiaoxu Song ◽  
Weston Grove ◽  
Emmett Hull ◽  
Z. J. Pei ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Additive Manufacturing ◽  
Microwave Irradiation ◽  
Computer Aided Design ◽  
Fused Deposition Modeling ◽  
Layer By Layer ◽  
Sem Images ◽  
Fused Deposition ◽  
Deposition Modeling

Additive manufacturing (AM) is a class of manufacturing processes where material is deposited in a layer-by-layer fashion to fabricate a three-dimensional part directly from a computer-aided design model. With a current market share of 44%, thermoplastic-based additive manufacturing such as fused deposition modeling (FDM) is a prevailing technology. A key challenge for AM parts (especially for parts made by FDM) in engineering applications is the weak inter-layer adhesion. The lack of bonding between filaments usually results in delamination and mechanical failure. To address this challenge, this study embedded carbon nanotubes into acrylonitrile butadiene styrene (ABS) thermoplastics via a filament extrusion process. The vigorous response of carbon nanotubes to microwave irradiation, leading to the release of a large amount of heat, is used to melt the ABS thermoplastic matrix adjacent to carbon nanotubes within a very short time period. This treatment is found to enhance the inter-layer adhesion without bulk heating to deform the 3D printed parts. Tensile and flexural tests were performed to evaluation the effects of microwave irradiation on mechanical properties of the specimens made by FDM. Scanning electron microscopic (SEM) images were taken to characterize the fracture surfaces of tensile test specimens. The actual carbon nanotube contents in the filaments were measured by conducting thermogravimetric analysis (TGA). The effects of microwave irradiation on the electrical resistivity of the filament were also reported.

vELECTROPLATING POLYMER BASED ADDITIVE MANUFACTURED PARTS FOR ENHANCED STRUCTURAL PERFORMANCE

2021 ◽  
Author(s):  
WARUNA SENEVIRATNE, ◽  
JOHN TOMBLIN ◽  
BRANDON SAATHOFF
Keyword(s):  
Additive Manufacturing ◽  
Fused Deposition Modeling ◽  
Thickness Variation ◽  
Manufacturing Processes ◽  
Fused Deposition ◽  
Aerospace Applications ◽  
Electroplated Coating ◽  
Traditional Manufacturing ◽  
Plastic Parts ◽  
Subtractive Machining

Additive manufacturing has been adopted in many aerospace and defense applications to reduce weight and buy-to-fly ratios of low-volume high- complexity parts. Polymer-based additive manufacturing processes such as Fused Deposition Modeling (FDM) has enabled aerospace manufactures to improve the structural efficiency of parts through generative design or topology optimization. This level of design freedom did not exist in the past due to limitations associated with traditional manufacturing processes such as subtractive machining. Improvements in the material and the maturation of the FDM process has led to the production of many non-structural flightworthy parts used in aircraft today. Polymer-based additive manufacturing can be further leveraged in aerospace applications with the addition of electroplated coatings that act as reinforcement. While many of the commonly known electroplated coating applications involve enhancing the part appearance, electroplated coatings can also improve the strength, stiffness, and durability of plastic parts. Depending on the use case, the thickness of the metallic plating material (combination of copper and nickel) can be tailored to achieve the desired composite properties (metal and polymer). In this research, the tensile and flexural mechanical properties were assessed for Ultem™ 9085 FDM printed specimens and compared to specimens with metallic coating thicknesses of approximately 75-μm, 150-μm, and 300-μm. Non- destructive inspections using x-ray computed tomography were performed prior to mechanical testing to assess the electroplated coating thickness variation and overall quality.

CubeSat Fabrication through Additive Manufacturing and Micro-Dispensing

2011 ◽  
Vol 2011 (1) ◽  
pp. 001021-001027 ◽  
Author(s):  
Cassie Gutierrez ◽  
Rudy Salas ◽  
Gustavo Hernandez ◽  
Dan Muse ◽  
Richard Olivas ◽  
...  
Keyword(s):  
Additive Manufacturing ◽  
Computer Aided Design ◽  
Printed Circuit Boards ◽  
Fused Deposition Modeling ◽  
Integrated Approach ◽  
Layer By Layer ◽  
New Paradigm ◽  
Spatial Gradients ◽  
Fused Deposition ◽  
On Demand

Fabricating entire systems with both electrical and mechanical content through on-demand 3D printing is the future for high value manufacturing. In this new paradigm, conformal and complex shapes with a diversity of materials in spatial gradients can be built layer-by-layer using hybrid Additive Manufacturing (AM). A design can be conceived in Computer Aided Design (CAD) and printed on-demand. This new integrated approach enables the fabrication of sophisticated electronics in mechanical structures by avoiding the restrictions of traditional fabrication techniques, which result in stiff, two dimensional printed circuit boards (PCB) fabricated using many disparate and wasteful processes. The integration of Additive Manufacturing (AM) combined with Direct Print (DP) micro-dispensing and robotic pick-and-place for component placement can 1) provide the capability to print-on-demand fabrication, 2) enable the use of micron-resolution cavities for press fitting electronic components and 3) integrate conductive traces for electrical interconnect between components. The fabrication freedom introduced by AM techniques such as stereolithography (SL), ultrasonic consolidation (UC), and fused deposition modeling (FDM) have only recently been explored in the context of electronics integration and 3D packaging. This paper describes a process that provides a novel approach for the fabrication of stiff conformal structures with integrated electronics and describes a prototype demonstration: a volumetrically-efficient sensor and microcontroller subsystem scheduled to launch in a CubeSat designed with the CubeFlow methodology.

scholarly journals A Review Study on Mechanical Properties of Obtained Products by FDM Method and Metal/Polymer Composite Filament Production

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Ümit Çevik ◽  
Menderes Kam
Keyword(s):  
Mechanical Properties ◽  
Additive Manufacturing ◽  
Polymer Composite ◽  
Fused Deposition Modeling ◽  
Three Dimensional ◽  
Production Method ◽  
Context Analysis ◽  
Fused Deposition ◽  
Composite Filament ◽  
Metal Polymer

In addition to traditional manufacturing methods, Additive Manufacturing (AM) has become a widespread production technique used in the industry. The Fused Deposition Modeling (FDM) method is one of the most known and widely used additive manufacturing techniques. Due to the fact that polymer-based materials used as depositing materials by the FDM method in printing of parts have insufficient mechanical properties, the technique generally has limited application areas such as model making and prototyping. With the development of polymer-based materials with improved mechanical properties, this technique can be preferred in wider application areas. In this context, analysis of the mechanical properties of the products has an important role in the production method with FDM. This study investigated the mechanical properties of the products obtained by metal/polymer composite filament production and FDM method in detail. It was reviewed current literature on the production of metal/polymer composite filaments with better mechanical properties than filaments compatible with three-dimensional (3D) printers. As a result, it was found that by adding reinforcements of composites in various proportions, products with high mechanical properties can be obtained. Thus, it was predicted that the composite products obtained in this way can be used in wider application areas.

A Robust True Direct-Print Technology for Tissue Engineering

2007 ◽  
Author(s):  
B. Li ◽  
T. Dutta Roy ◽  
C. M. Smith ◽  
P. A. Clark ◽  
K. H. Church
Keyword(s):  
Tissue Engineering ◽  
Computer Aided Design ◽  
Fused Deposition Modeling ◽  
Three Dimensional ◽  
Layer By Layer ◽  
Fused Deposition ◽  
Wide Range ◽  
Computer Aided ◽  
Liquid Material ◽  
Print Process

Numerous solid freeform fabrication (SFF) or rapid prototyping (RP) techniques have been employed in the field of tissue engineering to fabricate specially organized three-dimensional (3-D) structures such as scaffolds. Some such technologies include, but are not limited to, laminated object manufacturing (LOM), three-dimensional printing (3-DP) or ink-jet printing, selective laser sintering (SLS), and fused deposition modeling (FDM). These techniques are capable of rapidly producing highly complex 3-D scaffolds or other biomedical structures with the aid of a computer-aided design (CAD) system. However, they suffer from lack of consistency and repeatability, since most of these processes are not fully controlled and cannot reproduce the previous work with accuracy. Also, these techniques (excluding FDM) are not truly direct-print processes. Certain material removing steps are involved, which in turn increases the complexity and the cost of fabrication. The FDM process has good repeatability; however, the materials that can be used are limited due to the high temperature needed to melt the feedstock. Some researchers also reported that the scaffolds fabricated by FDM lack consistency in the z-direction. In this paper, we will present a true direct-print technology for repeatedly producing scaffolds and other biomedical structures for tissue engineering with the aid of our Computer Aided Biological (CAB) tool. Unlike other SFF techniques mentioned above, our direct-print process fabricates scaffolds or other complex 3-D structures by extruding (dispensing) a liquid material onto the substrate with a prescribed pattern generated by a CAD program. This can be a layer-by-layer 2.5 dimension build or a true 3-D build. The dispensed liquid material then polymerizes or solidifies, to form a solid structure. The flexibility in the types of materials that can be extruded ranges from polymers to living cells, encapsulated in the proper material. True 3-D structures are now possible on a wide range of substrates, including even in vivo. Some of the advantages of the process are a) researchers have full control over the patterns to be created; b) it is a true direct-print process with no material removing steps involved; c) it is highly consistent and repeatable; and d) it is highly efficient and cost-effective. This paper will first give a detailed description of the CAB tool. Then, it will present a detailed process for printing polycaprolactone (PCL) into a defined 3-D architecture, where the primary focus for these constructs is for use in tissue engineering applications. Finally, mechanical characterization results of the printed scaffolds will be included in the paper.

3D printing of generative art using the assembly and deformation of direction-specified parts

2016 ◽  
Vol 22 (4) ◽  
pp. 636-644 ◽  
Author(s):  
Yaususi Kanada
Keyword(s):  
3D Printing ◽  
Computer Aided Design ◽  
Fused Deposition Modeling ◽  
Three Dimensional ◽  
3D Models ◽  
Control Technique ◽  
Content Type ◽  
Fused Deposition ◽  
A New Technique ◽  
Printing Direction

Purpose A methodology for designing and printing three-dimensional (3D) objects with specified printing-direction using fused deposition modeling (FDM), which was proposed by a previous paper, enables the expression of natural directions, such as hair, fabric or other directed textures, in modeled objects. This paper aims to enhance this methodology for creating various shapes of generative visual objects with several specialized attributes. Design/methodology/approach The proposed enhancement consists of two new methods and a new technique. The first is a method for “deformation”. It enables deforming simple 3D models to create varieties of shapes much more easily in generative design processes. The second is the spiral/helical printing method. The print direction (filament direction) of each part of a printed object is made consistent by this method, and it also enables seamless printing results and enables low-angle overhang. The third, i.e. the light-reflection control technique, controls the properties of filament while printing with transparent polylactic acid. It enables the printed objects to reflect light brilliantly. Findings The proposed methods and technique were implemented in a Python library and evaluated by printing various shapes, and it is confirmed that they work well, and objects with attractive attributes, such as the brilliance, can be created. Research limitations/implications The methods and technique proposed in this paper are not well-suited to industrial prototyping or manufacturing that require strength or intensity. Practical implications The techniques proposed in this paper are suited for generatively producing various a small number of products with artistic or visual properties. Originality/value This paper proposes a completely different methodology for 3D printing than the conventional computer-aided design (CAD)-based methodology and enables products that cannot be created by conventional methods.

scholarly journals A Review of 3D Printing in Dentistry: Technologies, Affecting Factors, and Applications

Scanning ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-19
Author(s):  
Yueyi Tian ◽  
ChunXu Chen ◽  
Xiaotong Xu ◽  
Jiayin Wang ◽  
Xingyu Hou ◽  
...  
Keyword(s):  
3D Printing ◽  
Computer Aided Design ◽  
Fused Deposition Modeling ◽  
Complex Geometry ◽  
Maxillofacial Surgery ◽  
Three Dimensional ◽  
Oral And Maxillofacial Surgery ◽  
Affecting Factors ◽  
Fused Deposition ◽  
Oral Implantology

Three-dimensional (3D) printing technologies are advanced manufacturing technologies based on computer-aided design digital models to create personalized 3D objects automatically. They have been widely used in the industry, design, engineering, and manufacturing fields for nearly 30 years. Three-dimensional printing has many advantages in process engineering, with applications in dentistry ranging from the field of prosthodontics, oral and maxillofacial surgery, and oral implantology to orthodontics, endodontics, and periodontology. This review provides a practical and scientific overview of 3D printing technologies. First, it introduces current 3D printing technologies, including powder bed fusion, photopolymerization molding, and fused deposition modeling. Additionally, it introduces various factors affecting 3D printing metrics, such as mechanical properties and accuracy. The final section presents a summary of the clinical applications of 3D printing in dentistry, including manufacturing working models and main applications in the fields of prosthodontics, oral and maxillofacial surgery, and oral implantology. The 3D printing technologies have the advantages of high material utilization and the ability to manufacture a single complex geometry; nevertheless, they have the disadvantages of high cost and time-consuming postprocessing. The development of new materials and technologies will be the future trend of 3D printing in dentistry, and there is no denying that 3D printing will have a bright future.

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