scholarly journals Increase in searches for erectile dysfunction during winter: seasonal variation evidence from Google Trends in the United States

2021 ◽  
Author(s):  
Belén Mora Garijo ◽  
Jonathan E. Katz ◽  
Aubrey Greer ◽  
Mia Gonzalgo ◽  
Alejandro García López ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
United States ◽  
Erectile Dysfunction ◽  
Seasonal Variation ◽  
Kidney Stones ◽  
Seasonal Pattern ◽  
The United States ◽  
Google Trends ◽  
Internet Search ◽  
Search Volume

AbstractSeveral diseases associated with erectile dysfunction (ED), such as type 2 diabetes mellitus (T2DM) and coronary artery disease (CAD), are known to have seasonal variation, with increased incidence during winter months. However, no literature exists on whether this chronological-seasonal evolution is also present within ED symptomatology. We hypothesized ED would follow the seasonal pattern of its lifestyle-influenced comorbid conditions and exhibit increased incidence during winter months. In order to investigate the seasonal variation of ED in the United States between 2009 and 2019, Internet search query data were obtained using Google Trends. Normalized search volume was determined during the winter and summer seasons for ED, other diseases known to be significantly associated with ED (T2DM and CAD), kidney stones (positive control), and prostate cancer (negative control). There were significantly more internet search queries for ED during the winter than during the summer (p = 0.001). CAD and T2DM also had significantly increased search volume during winter months compared to summer months (p < 0.001 and p = 0.011, respectively). By contrast, searches for kidney stones were significantly increased in the summer than in the winter (p < 0.001). There was no significant seasonal variation in the relative search frequency for prostate cancer (p = 0.75). In conclusion, Google Trends internet search data across a ten-year period in the United States suggested a seasonal variation in ED, which implies an increase in ED during winter. This novel finding in ED epidemiology may help increase awareness of ED’s associated lifestyle risk factors, which may facilitate early medical evaluation and treatment for those at risk of both ED and cardiovascular disease.

scholarly journals Estimating the Outpatient Burden of Venous Thromboembolism in the United States: An Analysis of Google Trends Data from 2004 to 2015

Blood ◽  
2015 ◽  
Vol 126 (23) ◽  
pp. 4453-4453 ◽  
Author(s):  
Adeel M Khan ◽  
Alok A. Khorana
Keyword(s):  
United States ◽  
Venous Thromboembolism ◽  
Varicose Veins ◽  
Blood Clot ◽  
Seasonal Pattern ◽  
The United States ◽  
Google Trends ◽  
Internet Search ◽  
Advisory Committees ◽  
Search Terms

Abstract Background: Analysis of internet search traffic has provided a new proxy measure into the trends and patterns of patients' diseases and their information-seeking behaviors. In recent years, Google Trends has become a data resource of interest given its status as the largest internet search provider in the world with publicly-viewable, passively-collected, and expansive data on any searchable term or combination of terms. For instance, search terms related to influenza (e.g. fever) predicted influenza spread faster than standard surveillance as shown by Ginsberg et al in Nature 2009. The true outpatient burden and incidence of venous thromboembolism (VTE) has long been debated. Extant VTE data are limited to cases that present to medical attention, thus missing any cases that do not come to an emergency department or clinic. We hypothesized that Google Trends analysis offers potential insight into the general populations' blood clot burden and awareness. This study aimed to explore general trends of VTE-related terms and seasonal variation in searches. Methods: Google Trends was utilized to obtain relative search engine traffic values (defined as search volume indices, SVIs) for terms related to DVT in the United States from summer 2004 - winter 2015. Terms related to LEG SWELLING, CALF PAIN, VARICOSE VEINS, and LEG CLOT were used and combined with Boolean operators to combine similar terms. A separate search occurred for BLOOD CLOT and related terms to investigate awareness of VTEs. Analysis was performed in R (V3.1.1) in accordance with previously published Google Trends investigations. Results: The average relative volume of searches was highest for VARICOSE VEINS and lowest for LEG SWELLING by approximately 3.2 fold. A seasonal pattern was seen with summer months (May-Aug) having higher SVIs than winter months (Nov-Feb) for all terms in the 11 year study period except for BLOOD CLOT. Using a Wilcoxon signed rank test, mean SVI difference comparing summer to winter for LEG SWELLING showed W = 66 (p = 0.004), for CALF PAIN W = 66 (p = 0.003), for VARICOSE VEINS W = 67 (p = 0.004), and for LEG CLOT W = 65 (p = 0.005). For BLOOD CLOT, a gradual increase in SVIs was seen and characterized by a Mann-Kendall test as having a significant positive trend, S = 898, p = 0.024. Conclusions: Search terms related to VTE in the United States show a strong seasonal pattern with greater search activity in summer months compared to winters months. These data suggest a higher incidence and burden of VTE in the summer. This challenges previous notions of a weakly higher incidence of VTE in winter months, calculated as a relative risk of 1.143 by Dentali et al in 2011. The gradual increase in relative search traffic for BLOOD CLOT terms reflects a likely rising awareness and/or true rise in the incidence of VTEs in the United States from 2004-2015. Further studies should investigate whether internet search traffic correlates directly with total yearly DVT incidence rates. Keywords: Population, venous thromboembolism, incidence Figure 1. Figure 1. Figure 2. Figure 2. Disclosures Khorana: Leo Pharma: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Janssen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Daiichi Sankyo: Consultancy, Honoraria; sanofi: Consultancy, Honoraria; Pfizer: Consultancy, Honoraria; Boehringer-Ingelheim: Consultancy, Honoraria.

scholarly journals Population-Level Interest and Telehealth Capacity of US Hospitals in Response to COVID-19: Cross-Sectional Analysis of Google Search and National Hospital Survey Data (Preprint)

2020 ◽  
Author(s):  
Young-Rock Hong ◽  
John Lawrence ◽  
Dunc Williams Jr ◽  
Arch Mainous III
Keyword(s):  
United States ◽  
Health Care ◽  
Population Level ◽  
The United States ◽  
Health Care Facilities ◽  
Care Providers ◽  
Internet Search ◽  
American Hospital ◽  
Search Volume ◽  
Google Search

BACKGROUND As the novel coronavirus disease (COVID-19) is widely spreading across the United States, there is a concern about the overloading of the nation’s health care capacity. The expansion of telehealth services is expected to deliver timely care for the initial screening of symptomatic patients while minimizing exposure in health care facilities, to protect health care providers and other patients. However, it is currently unknown whether US hospitals have the telehealth capacity to meet the increasing demand and needs of patients during this pandemic. OBJECTIVE We investigated the population-level internet search volume for telehealth (as a proxy of population interest and demand) with the number of new COVID-19 cases and the proportion of hospitals that adopted a telehealth system in all US states. METHODS We used internet search volume data from Google Trends to measure population-level interest in telehealth and telemedicine between January 21, 2020 (when the first COVID-19 case was reported), and March 18, 2020. Data on COVID-19 cases in the United States were obtained from the Johns Hopkins Coronavirus Resources Center. We also used data from the 2018 American Hospital Association Annual Survey to estimate the proportion of hospitals that adopted telehealth (including telemedicine and electronic visits) and those with the capability of telemedicine intensive care unit (tele-ICU). Pearson correlation was used to examine the relations of population search volume for telehealth and telemedicine (composite score) with the cumulative numbers of COVID-19 cases in the United States during the study period and the proportion of hospitals with telehealth and tele-ICU capabilities. RESULTS We found that US population–level interest in telehealth increased as the number of COVID-19 cases increased, with a strong correlation (<i>r</i>=0.948, <i>P</i>&lt;.001). We observed a higher population-level interest in telehealth in the Northeast and West census region, whereas the proportion of hospitals that adopted telehealth was higher in the Midwest region. There was no significant association between population interest and the proportion of hospitals that adopted telehealth (<i>r</i>=0.055, <i>P</i>=.70) nor hospitals having tele-ICU capability (<i>r</i>=–0.073, <i>P</i>=.61). CONCLUSIONS As the number of COVID-19 cases increases, so does the US population’s interest in telehealth. However, the level of population interest did not correlate with the proportion of hospitals providing telehealth services in the United States, suggesting that increased population demand may not be met with the current telehealth capacity. Telecommunication infrastructures in US hospitals may lack the capability to address the ongoing health care needs of patients with other health conditions. More practical investment is needed to deploy the telehealth system rapidly against the impending patient surge.

Vardenafil in Erectile Dysfunction: The Evidence of Its Therapeutic Value

2010 ◽  
Vol 2 ◽  
pp. CMT.S3787
Author(s):  
Kevin R. Rice ◽  
Robert C. Dean
Keyword(s):  
Prostate Cancer ◽  
United States ◽  
Erectile Dysfunction ◽  
Therapeutic Efficacy ◽  
The United States ◽  
Oral Medication ◽  
Phosphodiesterase 5 Inhibitors ◽  
Therapeutic Value ◽  
Primary Literature ◽  
Phosphodiesterase 5

Erectile dysfunction (ED) is a condition that affects approximately 18 million American men. Phosphodiesterase-5 inhibitors (PDE5i's) have revolutionized the treatment of erectile dysfunction by providing the first highly-effective oral medication. Vardenafil is one of 3 PDE5i's commercially available for the treatment of ED in the United States. It has demonstrated therapeutic efficacy in the management of uncomplicated ED as well as more refractory cases associated with diabetes and surgery for prostate cancer. The physiology, pharmacokinetics, pharmacodynamics, and primary literature evaluating vardenafil are reviewed.

scholarly journals Breast Cancer Awareness Month: The Impact of Even the Most Successful Campaigns Fades

2020 ◽  
Author(s):  
Frédéric Lapostolle ◽  
Lisa Weisslinger ◽  
Charles Durand ◽  
Frédéric Adnet
Keyword(s):  
Breast Cancer ◽  
United States ◽  
Public Information ◽  
The United States ◽  
Google Trends ◽  
Cancer Awareness ◽  
Search Volume ◽  
Breast Cancer Awareness ◽  
Internet Searches ◽  
The Impact

Abstract BackgroundFor over 35 years the ‘Breast Cancer Awareness Month’ (BCAM) has worked to increase public information about breast cancer and to raise funds for research. The aim of this study was to analyze how the interest generated by this campaign evolved over time, in the US and other countries.MethodsWe investigated the Google Trends® according to previously recommended methods. The study was based on Internet searches using the term ‘’breast cancer’’ worldwide and in the United-States. Google Trends® gives the relative search volume of every request as an index on a scale from 0 to 100, (100 corresponding to the maximum number of requests during the studied period). We compared the relative searches index using the term ‘’breast cancer’’ during October, the breast cancer awareness month, and the rest of the of the year avec a 10 years period.Results120 months were analyzed including 10 October months. Median index for worldwide searches on ‘’breast cancer’’ during the 110 months was 35 (34-39). It didn’t significantly change during the study period (R2=0,3). Median index of the 10 peaks was 83 (64-92) (p<0,001 vs 110 months). The peak index linearly decreased (R2=0,88) during the study period. It reached 100 in 2012 and 64 in 2020. In the United-States, median index for searches during the 110 months was 28 (26-32). It didn’t significantly change during the study period (R2=0,3). Median index of the 10 peaks was 83 (63-92) (p<0,001 vs 110 months). The peak index linearly decreased (R2=0,73) during the study period. It reached 100 in 2012 and 64 in 2020.ConclusionsThis internet activity study shows that the impact of the ‘Breast Cancer Awareness Month’ seems to be slowly decreasing. The number of Internet searches generated by the campaign has been reduced by almost 40% in both the United-States and worldwide.

scholarly journals Research Interest and Public Interest in Melanoma: A Bibliometric and Google Trends Analysis

2021 ◽  
Vol 11 ◽  
Author(s):  
Hanlin Zhang ◽  
Yuanzhuo Wang ◽  
Qingyue Zheng ◽  
Keyun Tang ◽  
Rouyu Fang ◽  
...  
Keyword(s):  
Seasonal Variation ◽  
Public Interest ◽  
Treatment Options ◽  
The United States ◽  
Research Interest ◽  
Google Trends ◽  
Diagnostic Tools ◽  
Search Volume ◽  
Trends Analysis ◽  
Relative Search Volume

IntroductionMelanoma is a severe skin cancer that metastasizes quickly. Bibliometric analysis can quantify hotspots of research interest. Google Trends can provide information to address public concerns.MethodsThe top 15 most frequently cited articles on melanoma each year from 2015 to 2019, according to annual citations, were retrieved from the Web of Science database. Original articles, reviews, and research letters were included in this research. For the Google Trends analysis, the topic “Melanoma” was selected as the keyword. Online search data from 2004 to 2019 were collected. Four countries (New Zealand, Australia, the United States and the United Kingdom) were selected for seasonal analysis. Annual trends in relative search volume and seasonal variation were analyzed, and the top related topics and rising related topics were also selected and analyzed.ResultsThe top 15 most frequently cited articles each year were all original articles that focused on immunotherapy (n=8), omics (n=5), and the microbiome (n=2). The average relative search volume remained relatively stable across the years. The seasonal variation analysis revealed that the peak appeared in summer, and the valley appeared in winter. The diseases associated with or manifestations of melanoma, treatment options, risk factors, diagnostic tools, and prognosis were the topics in which the public was most interested. Most of the topics revealed by bibliometric and Google Trends analyses were consistent, with the exception of issues related to the molecular biology of melanoma.ConclusionThis study revealed the trends in research interest and public interest in melanoma, which may pave the way for further research.

Abstract 17380: Can Understanding of National Search Engine Queries Inform Heart Failure Prevention? National Internet Search Engine Queries Correlates With CHF Prevalence but Not Outcomes

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
adebayo atanda ◽  
Olajide Buhari ◽  
Mohammed Alarfaj ◽  
Hassan Khalil ◽  
Alberto Batresh ◽  
...  
Keyword(s):  
United States ◽  
Heart Failure ◽  
Congestive Heart Failure ◽  
Search Engine ◽  
The United States ◽  
Mortality Rates ◽  
Google Trends ◽  
Diagnostic Tools ◽  
Internet Search ◽  
Google Search

Introduction: Congestive heart failure (CHF) remains an epidemic with rising prevalence and a contributing cause of 1 in 9 deaths in the United States. An understanding of internet search engines for congestive heart failure as informational and initial diagnostic tools may enable targeted education strategies. Hypothesis: There is a correlation between CHF google search and outcomes. Methods: We used google trends, a publicly available google tool, to identify search frequency for CHF and related terms like early signs of heart failure, congestive heart failure facts over a 2 year period from 2014-2016 across regions of the United States. We then evaluated the prevalence of hospitalization and mortality rates among Medicare beneficiaries based on Center for Disease Control (CDC) data. Utilizing Pearson correlation (R) test, we determined the association between relative search frequency (RSF) in various states versus CHF hospitalization and mortality rates. Results: Across the 50 states in United States, there were 25 searches related to the search terms. There was a moderate positive correlation (R 0.4-0.7) between CHF hospitalization (R= 0.43) and mortality (R=0.51) with relative search frequency in google trends. Conclusions: We demonstrated a correlation between internet search and CHF prevalence and hospitalization. The emergence of data analytics in CHF care may enable greater understanding of patient questions in CHF to better target education and prevention.

Abstract 51: Seasonal Variation in Out-of-Hospital Cardiac Arrest

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Awani Deshmukh ◽  
Nileshkumar J Patel ◽  
Abhishek Deshmukh ◽  
Neil Patel ◽  
Achint Patel ◽  
...  
Keyword(s):  
United States ◽  
Cardiac Arrest ◽  
Seasonal Variation ◽  
Seasonal Pattern ◽  
The United States ◽  
Annual Number ◽  
Inhospital Mortality ◽  
Nationwide Inpatient Sample Database ◽  
The Mean ◽  
Hospital Cardiac Arrest

Introduction: Heart Disease and Stroke Statistics_2014 Update suggests more than 424,000 people suffer out of hospital cardiac arrest (OHCA) in the United States. Hypothesis: We assessed seasonal variation in OHCA from a large national hospitalisation database in the past decade. Methods: The Nationwide Inpatient Sample database was used to estimate the annual number of hospitalisations with from 2000-2011. Identification of out of hospital cardiac arrest related hospitalisations was based on the designation of the International Classification of Diseases (9th Edition) Clinical Modification (ICD-9-CM) diagnosis code 427.5 (OHCA) as the principal discharge diagnosis. The frequency of hospitalisation for each month cumulative over 11 years was calculated and divided by number of days in that month to obtain the mean hospitalisations per day for each month. All calculations were carried out using the weighted estimates approximating nationwide population estimates. Results: An estimated 93,209 hospitalisations with primary diagnosis of OHCA occurred in the United States from the beginning of the calendar year 2000 to the end of the calendar year 2011. The number of hospitalisations per day in each month is shown in Figure 1.The number of hospitalisation was maximum in the winter months and minimum in summer months. Specifically, the mean number of hospitalisation each day (averaged over 11 years) was least in August (242). There was a rising trend from August to January. The average number of hospitalisation was highest in January (310); thereafter, the hospitalisation rate dropped to a nadir in August. There was however no seasonal pattern in inhospital mortality. Conclusions: We identified for the first time in United States an impressive pattern of seasonal variation in hospitalisations for OHCA. Further efforts must be made to identify triggers and methods to prevent OHCA and reduce its burden on health care system.

scholarly journals Population-Level Interest and Telehealth Capacity of US Hospitals in Response to COVID-19: Cross-Sectional Analysis of Google Search and National Hospital Survey Data

10.2196/18961 ◽  
2020 ◽  
Vol 6 (2) ◽  
pp. e18961 ◽  
Author(s):  
Young-Rock Hong ◽  
John Lawrence ◽  
Dunc Williams Jr ◽  
Arch Mainous III
Keyword(s):  
United States ◽  
Health Care ◽  
Population Level ◽  
The United States ◽  
Health Care Facilities ◽  
Care Providers ◽  
Internet Search ◽  
American Hospital ◽  
Search Volume ◽  
Google Search

Background As the novel coronavirus disease (COVID-19) is widely spreading across the United States, there is a concern about the overloading of the nation’s health care capacity. The expansion of telehealth services is expected to deliver timely care for the initial screening of symptomatic patients while minimizing exposure in health care facilities, to protect health care providers and other patients. However, it is currently unknown whether US hospitals have the telehealth capacity to meet the increasing demand and needs of patients during this pandemic. Objective We investigated the population-level internet search volume for telehealth (as a proxy of population interest and demand) with the number of new COVID-19 cases and the proportion of hospitals that adopted a telehealth system in all US states. Methods We used internet search volume data from Google Trends to measure population-level interest in telehealth and telemedicine between January 21, 2020 (when the first COVID-19 case was reported), and March 18, 2020. Data on COVID-19 cases in the United States were obtained from the Johns Hopkins Coronavirus Resources Center. We also used data from the 2018 American Hospital Association Annual Survey to estimate the proportion of hospitals that adopted telehealth (including telemedicine and electronic visits) and those with the capability of telemedicine intensive care unit (tele-ICU). Pearson correlation was used to examine the relations of population search volume for telehealth and telemedicine (composite score) with the cumulative numbers of COVID-19 cases in the United States during the study period and the proportion of hospitals with telehealth and tele-ICU capabilities. Results We found that US population–level interest in telehealth increased as the number of COVID-19 cases increased, with a strong correlation (r=0.948, P<.001). We observed a higher population-level interest in telehealth in the Northeast and West census region, whereas the proportion of hospitals that adopted telehealth was higher in the Midwest region. There was no significant association between population interest and the proportion of hospitals that adopted telehealth (r=0.055, P=.70) nor hospitals having tele-ICU capability (r=–0.073, P=.61). Conclusions As the number of COVID-19 cases increases, so does the US population’s interest in telehealth. However, the level of population interest did not correlate with the proportion of hospitals providing telehealth services in the United States, suggesting that increased population demand may not be met with the current telehealth capacity. Telecommunication infrastructures in US hospitals may lack the capability to address the ongoing health care needs of patients with other health conditions. More practical investment is needed to deploy the telehealth system rapidly against the impending patient surge.

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